Gene

KWMTBOMO14918  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000774

Annotation

carboxyl/cholinesterase_6_precursor_[Bombyx_mori]

Location

Bomo_Chr25(-):415532-424742      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 2.134

CDS

ATGATAAGACTGGGTCTGGTGATGCTGTTCCTAATACCTGGAACAGAACAGAATGTAATCAGTATAGCTCAGGGGAAGATACGGGGACGCGTCAGAGATGGTTACGTGACGTATGGCGGTATACCTTATGGATCTCTGATGCTTAAGGGGAGATTTAAGCAAGCCGGCATAGCTCCCGTTTGGCCTAACATACGAGAGTTCCACGAATCTCGCTGTTCAACAACTTCCGCCGCCGAGGAGTGTCTGCAGCTCGACGTCAACGTGCCCACGTCGGCTGCTCCAACGTGGCCTGTACTAGTCTGGGTCACAGGTTCAGACGGAAGTTATCACTCTGGACAACTGGTCAAGAAGGGAGTTATTGTAGTCATTGTGCGTCACAGGTTAGGCGCCCCTGGATTCTTATGCTACGAAAGAGATATACCAGGAAACGCAGGCGCAAAAGACGTTATAGCAGCATTACACTGGGTCAGAGACAACATAATTGCTTTCAAAGGAAACCCGGCAAGAGTTGTCGTCGCGGGCCAGGGTTTTGGAGCTGCCATGGTGGAAGCATTAACACTTACCCCAATGGCTGAAGGACTGTTCCACGGTGTTATATTGCAAAGCGGCAGCATATTAGCTCCGTGGGCTTTCAACTATGATGCCAAAGACAGGGCCAAAGTTATCGGAGAGCGTTTAGACAAAAAACGAGATTATGTCGATGTTTTTTTAAATGCCACAATGGAAGAATTATTTATTAAATCAAGTGAATCGAACACGCCATATTTCTCTTTTGGCCTTTGTCTGGAAGAACCACTGAAGAATGAGGAGCGGTTTTTCTTGGAGACGCCTTACGATTTGTTCGTGACAAAGAAGTCTAAATCTGTTCCAATGATAATCGGCTACAATAGTGATGAAGCGTATATATTCTCATCACTACTAAAGGAGTTTAAGGTTATTAATAAATTAACTAAAGATATTAGCTTTTTACTGCCATACGAGTTGCAATTTTTAAATAGTAGAGAAATGAATCAAGTTTCTCGACAAATCGAGGACATTTACTTCAGAAGAAATCGTACAATGACTGCTCTGCTGGCTTACCACAGGGACGTATACTTTTTAAGCCATGTTTATCGAAGTGCCAGTTATCACGCCGCGGTGTCATCCCTTGTCTACTTCTACACGTTTTCACACCTTGGAGAAGTCGGCGTTCAAAAAGAACCTGGAATCCAGAAAAGCGGAGCCGCTCATTCAGATGAACTTGCATATCTATTTTCTGGGCGAAATCTGGATAAAGAAGACGGCCTTGTCCAAGACCTTTTGGTACGATTTTGGGTCAACTTCGTGATACATTTAAATCCAACTCACCGACAACCACTTGACTGGGATCCAATGAATTACGAAAACCCTCGCCTACTCGATATAGGCGTTGAACCTAAGATGATCGACTACCCTTACGAGAAGACTTCAAAATTTTGGGAAGAAATTTATGACAATTCAGTTACCCTGATTTTAATTGGTTCAGCGATATATGCAGAGTCCTTCACTAAAAAATGTGATGTGCTGGTGAAGTTAGACTCGGGACCTGTGTGCGGGAGAGAGGAGAGCGCAAACAAAAATACCAAATACTTCAGTTTCCAGGGCATTCCGTATGCGAAGCCACCCGTAGGCGCCAGAAGATTTTCTGAACTGGAGCCACTTGAGCCATGGTCTGAACCGTTCTACGCTTACGAAGAAGGGCCGGCCTGTCCGTCGAGAGATATTACTTACGGCAGTATTACCGTCAAACGCAAAGGAATGAGTGAAAACTGTATTTATGCTAATGTATTTGTACCGGCGTCTGCGACTCTGAACAGCGATGAACTTTGCGAAGACAATTCACTGCCCATATTGGTGAATATCCACGGTGGTGGGTTCCAAACAGGATCTGGCAATAGAGATTTGCATGGACCGGAATTGTTGATGTTAAAAGATGTCATTGTAGTAAATTTTAATTACAGATTGGCCATTTTCGGATACTTGTCTCTTGCTTCTCATAAGATTCCTGGTAATAATGGACTGCGAGACATGGTGACGCTGCTAAAGTGGGTGCAGAGAAATGCAAAAGTATTCGGGGGAGACCCTAAGCGAGTGACAATACTCGGAGAAAGTGCTGGAGCAGCATCAGTACACCTTCTCATGTTGTCTCGGGCCTCCAAAGGACTATTCAACAAAGCTATTATAATGAGTGGTACCGCTATACCAAACTTCTATAGCTCGTCCCCAATATATGCCAAATACATCTCCGACATGTTTCTCGGAGAACTAGGTTTAAACTCTACCGAGTTAACGTCTGATGAAATTCATCAGACTTTAACTGAATTACCGTTAGATGATATTATGAGAGCCAATGACGTTGTGCAATACAGAGCGGGTTTAACTTCGTTCGTTCCGGTTGTAGAGAAAGAGGGTCATGATTATACCAGGATCATTGACGATGATCCGATTACTTTAATTAATCAAGGTGTGGGCAAGGACATTCCCTTACTAATGGGTTTCAATAAGGATGAAGGTGAATATTTCAAATGGATAATCACTATTTACAATATTGTGGACCGTTATAAAAGTAATCCGGCAGTTATTTTATCGCCAAGACTGGCGTACGAGTTGCCCCCACAAGAAGCTTCAGCCAAAGGAATATTCGTGGGGAAAAGATATTTTGACGGTGAGCCCACAGTGGATGGATTCGTAAAAAGCGTGACGGATATTTACTTTCAATATCCTATGATCAAACTGGCACAATGGAGAATACTTTTGAATTCGGCGCCGACATATTTTTACGAATTTTCGTATGAAAGCGACTTCAGCATTACAAAGAGAGCCAACTGGTTAAGCTACAAAGGAACTGCTCATGTCGAGGATCTGACGTACGTGTTCCACACTACCACGTTTCTCGGAAGTCAAGTGTCAGTGCCTCCTAAAACCAGAGATGACCAAATGAGGGATTGGATGTCTACTTTATTCAGTAACTACGTAAGATGCAATAATCCTACATGCAATAAGCGTGATGATCCTCGGTGGCCTCCCATTAACGAAGAAGAGTTAATGTTTCAAGTTATCAAAGAGCCCAATGTTTATAAGATGTCTTCATTACCAAAGCAGTTGGAGGACATGGTGGAATTCCATGACGGTGTAGACGATCAAGTCAGGATGCAGTCAGAAATCCTTAAGGAGCAAAAAAAGAAACATAGTATGTACCAGTAA

Protein

MIRLGLVMLFLIPGTEQNVISIAQGKIRGRVRDGYVTYGGIPYGSLMLKGRFKQAGIAPVWPNIREFHESRCSTTSAAEECLQLDVNVPTSAAPTWPVLVWVTGSDGSYHSGQLVKKGVIVVIVRHRLGAPGFLCYERDIPGNAGAKDVIAALHWVRDNIIAFKGNPARVVVAGQGFGAAMVEALTLTPMAEGLFHGVILQSGSILAPWAFNYDAKDRAKVIGERLDKKRDYVDVFLNATMEELFIKSSESNTPYFSFGLCLEEPLKNEERFFLETPYDLFVTKKSKSVPMIIGYNSDEAYIFSSLLKEFKVINKLTKDISFLLPYELQFLNSREMNQVSRQIEDIYFRRNRTMTALLAYHRDVYFLSHVYRSASYHAAVSSLVYFYTFSHLGEVGVQKEPGIQKSGAAHSDELAYLFSGRNLDKEDGLVQDLLVRFWVNFVIHLNPTHRQPLDWDPMNYENPRLLDIGVEPKMIDYPYEKTSKFWEEIYDNSVTLILIGSAIYAESFTKKCDVLVKLDSGPVCGREESANKNTKYFSFQGIPYAKPPVGARRFSELEPLEPWSEPFYAYEEGPACPSRDITYGSITVKRKGMSENCIYANVFVPASATLNSDELCEDNSLPILVNIHGGGFQTGSGNRDLHGPELLMLKDVIVVNFNYRLAIFGYLSLASHKIPGNNGLRDMVTLLKWVQRNAKVFGGDPKRVTILGESAGAASVHLLMLSRASKGLFNKAIIMSGTAIPNFYSSSPIYAKYISDMFLGELGLNSTELTSDEIHQTLTELPLDDIMRANDVVQYRAGLTSFVPVVEKEGHDYTRIIDDDPITLINQGVGKDIPLLMGFNKDEGEYFKWIITIYNIVDRYKSNPAVILSPRLAYELPPQEASAKGIFVGKRYFDGEPTVDGFVKSVTDIYFQYPMIKLAQWRILLNSAPTYFYEFSYESDFSITKRANWLSYKGTAHVEDLTYVFHTTTFLGSQVSVPPKTRDDQMRDWMSTLFSNYVRCNNPTCNKRDDPRWPPINEEELMFQVIKEPNVYKMSSLPKQLEDMVEFHDGVDDQVRMQSEILKEQKKKHSMYQ

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Uniprot

A0A212EHB0   A0A0L7LFI0   A0A1W4XHU4   A0A194Q3V9   A0A1W4WJL4   A0A084VDQ2   + More
A0A182Y3T5   A0A139WDB1   A0A182PSI4   A0A182VZM5   A0A139WFF6   A0A182JU79   A0A182NRT3   A0A2A3E5C0   A0A0L7L5N8   A0A1I8NLU5   A0A1B0G6N0   A0A0L7KNG8   A0A182WIA7   A0A182K2F0   A0A2H1VCP1   A0A182X1A6   A0A182FFU4   A0A182K987   A0A194QY63   A0A182FHW9   A0A182N7N5   A0A194RIH0   A0A1B0G4Z5   A0A0L7L9I4   A0A2H1WPZ4   A0A195EV77   A0A2A4JAV9  

Pubmed

22118469    26227816    26354079    24438588    25244985    18362917    + More
19820115   

EMBL

AGBW02014918    OWR40860.1    JTDY01001282    KOB74303.1    KQ459586    KPI98095.1    + More
ATLV01011649    ATLV01011650    KE524705    KFB36096.1    KQ971360    KYB25958.1    KQ971352    KYB26710.1    KZ288364    PBC26890.1    JTDY01002769    KOB70767.1    CCAG010009612    JTDY01007971    KOB64827.1    ODYU01001848    SOQ38618.1    KQ461154    KPJ08516.1    KQ460205    KPJ17125.1    CCAG010019794    JTDY01002125    KOB72049.1    ODYU01010136    SOQ55032.1    KQ981965    KYN31797.1    NWSH01002285    PCG68674.1   

Proteomes

UP000007151    UP000037510    UP000192223    UP000053268    UP000030765    UP000076408    + More
UP000007266    UP000075885    UP000075920    UP000075881    UP000075884    UP000242457    UP000092444    UP000076407    UP000069272    UP000053240    UP000078541    UP000218220   

Pfam

PF00135   COesterase        + More
PF00246   Peptidase_M14

Interpro

IPR002018   CarbesteraseB        + More
IPR029058   AB_hydrolase       
IPR019826   Carboxylesterase_B_AS       
IPR019819   Carboxylesterase_B_CS       
IPR002168   Lipase_GDXG_HIS_AS       
IPR008969   CarboxyPept-like_regulatory       
IPR000834   Peptidase_M14       

SUPFAM

SSF53474   SSF53474        + More
SSF49464   SSF49464       

Gene 3D

3.40.50.1820    

ProteinModelPortal

A0A212EHB0   A0A0L7LFI0   A0A1W4XHU4   A0A194Q3V9   A0A1W4WJL4   A0A084VDQ2   + More
A0A182Y3T5   A0A139WDB1   A0A182PSI4   A0A182VZM5   A0A139WFF6   A0A182JU79   A0A182NRT3   A0A2A3E5C0   A0A0L7L5N8   A0A1I8NLU5   A0A1B0G6N0   A0A0L7KNG8   A0A182WIA7   A0A182K2F0   A0A2H1VCP1   A0A182X1A6   A0A182FFU4   A0A182K987   A0A194QY63   A0A182FHW9   A0A182N7N5   A0A194RIH0   A0A1B0G4Z5   A0A0L7L9I4   A0A2H1WPZ4   A0A195EV77   A0A2A4JAV9  

PDB

2FJ0     E-value=1.04847e-128,     Score=1182

KEGG

100500760    no KO assigned | (RefSeq) cce-6, Bmcce-6; carboxyl/cholinesterase 6

GO

GO:0016787   GO:0005615   GO:0052689   GO:0004181   GO:0008270   GO:0016021  

SignalP

Position:   1 - 17,         Likelihood:  0.933011

 

 

Length:

1073

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.1068

Exp number, first 60 AAs:

0.02084

Total prob of N-in:

0.00187

outside

1  -  1073

 

 

Pi

223.815181

Theta

170.664725

Tajima's D

1.109655

CLR

0.169576

CSRT

0.687215639218039

Interpretation

Uncertain