Gene

KWMTBOMO14915

Pre Gene Modal

BGIBMGA000777

Annotation

PREDICTED:_esterase_FE4-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr25(-):373491-381952      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 2.331

CDS

ATGCACGGTGGAATACTTTTTATATTAGTTGTCACTGCCACTACCGTAGCAGGACTCGAATTGACAATTGACGACTTGCTTCAACAACAGTCCCCAGAGTTAATAACAGACAGTACCAGCTCTCCTCGACCAGACGATGGAGCGATTAGCACACCAAGCGGGAACATGGGCAGCACTGATGACGTAGTCACGACTACTGAAGTTGAAACAACTATAAAACCCTCAGTTACTGACGAAAACGTTTCTATCACCACCTTGAGGATAGAAACGGAAGCACCAACCACTGGTCTCACGGATAGAACCGAGAGTGAGGCACCTAGTATGGAACAGAACAACCTGATCGAGACTACACACGGTTTAGTTAGGGGATTTGAATGGCACACCACGGGGGACATTATCAGCTACATCGACATACCTTATGCAAAATACACTAAGTATTTTGAGGAACCAAAGTCTTCCAATGCTTGGGAAACGACGCATGAAGTCCGAGAACACAAGTCTCGATGCCCACAATTACAAGGAGAATCAGTTGTGGGTAGTCAAGATTGCTTGACTTTGAGTATCTTTGCACCGACTAATGCCGAAAATGTCAGTGTTTTATTCCATATACACGAAAGTAACTTTGTCCAGGGCAGTGCTGACCCAGCTCTATACGGTCCGGAGTACTTAGTGTCCAAAGGGCTCATATTAGTTCTACCAAACTATAGATTGGGCCCATTGGGATTTTTGTGTTTAAGAAACACAATGGCTCCAGGTAACGCAGCTCTTAAGGATTTAAGTATGGCTCTACAGTGGATAAAGAATAACATTGCAAAATTTGGGGGGAATCCTGATACTATTGTGGTTAGTGGTGAGGGGACTTCTGGTGCGTTGATAGGCTTTTTGGCCTTGTCGTCTTCTTCAAGGAACTATTTTGATAAAGCTATAACAGAGAGCGGATCAGTTCTTTCGTATTGGGCTTTAGACCGAAATCCCGCATTGACTGGCGAAAAACTAACCGAAGCATTGACCAAAATAGACAACAGTCTTAATTTGGAAACTGCCGATATTCTGACAATATTAAGAGCTGCACAAAACATTCATTTCCGACCTTGTATTGAGAAAGGCAATAATCCTTTTATGACTCAAACTCCATGGGGAATGATACGAGAACAGGAAGTCAATATAACTTTTATGATTGGATCGGCAAACTACGCTGGCTTGAACGAGGCCTTAGATCAGAACGAAGCGAGCATTGAGCAGTTAAATGATGATTTTGCAACTCTGCTACCGGACGATTTGGCATTTGGTAGTGATATAGAAAGACAAAACGTAGTGAGAAACGTTAGATCTCAGTATTTTATAGAAAATAAGCCGATCACGTTAGAAGACCACATAGAAGGACTTTCACTGTGCTTTACTGATTCCTGTTTCTTAGGGCCAGCCATCAGAACTGCCAGATCTTTGGCTAATGCGGGAGCTAAAGTCTATTTCTACGAATTCAGTTTTACAGAATTAATTTCAGAATCGCATACTGTAGACAGACCAGTGGAAGGAGCGGTTCGCGGTGATATCAGAAACTACGTGTTCACTCAGGATGGCAGAATATTGACTGAAGGAACTGCTGAAAGGGAGGTCGTTGATATAATGGTCGATACGTGGTTTACTTTTATTGAAAACGGAAATCCAGTAGCGAACGAGACGGATTGGAACCGACTAACTGTGACCGTTCCAGCACAAGAAGAATGGATGCAGCTCGGTCCTGAAATCGGCTTAAAACAAGGACTGCACTTGAGCAGATTAAATTTATGGACTAACATCTACAACAACTATTTCATCGAAATGCGTAATAACGCGCCCAAGCCTCCTCCTCGGTGGGATGGAGTCTTCGAAGCAACGCATCGCGTAAAGTGCCCCCAGTTGGACATCGGAGATGAAAACTGTCTCGTTATTAACATATTCACTCCAGAAGTGAGTAATAACTTACCAGTCCTTGTTCATGTCCATGGAGGGGACTATCAGAATGGATGGGGATTTCATCAACCACCTATAAACCTAATTAACAAAGGTATCATAATAGTAACTTTTAACTACCGTATTGGTGTACTCGGTTTCCTATGCCTCGGAATTCCAGCAGCTCCCGGAAATGTAGGTTTGAAAGACCAGGTTGCTGCTCTTTACTGGATCCAACAAAATATAAAGAGATTTGGAGGTGATCCTAATGATGTTACATTGTATGGAACTGAGGCTGGTTCAATATCAATACAGTTGCTTTTACAAGCACGTCTCATGATGGGATTTCACAAAGTCATCTTGGAATCTGGGTCAATTTTGTCTCCTACAGCTTTGACCTACAATCCCATAGCTGATGCATTTGCAATCGGAGAACAATTAGGATATAATGACACAAATAACTCACATAAATTGCTGAAATACTTGCGGAAGCTTTCTGTAACAGTACTCTTGGATGCACATAAAATTTCCCTGCCTTGTGTTGAGAGTGTAAATAATGCTGAAAGTCTAATTGATAAAGATCCACTGCAACTACTGAAAGACGGACCAATTGACAATATCCCAATGCTTGTATCATATACTAGATTAAAATTAAGACATAATTCAGAAAAATTAAAAACAGTGCCAGAAGATTTTGTTGATTTACTTCCAAGCAACTTAGAATTTACCAATGATGGAATTAGATATAAGATTTCAGAATTAATTAAAGATTTTTACTTCTTTAAAGACATTGACACTTCTAGCAGTTATGAGAATTATTTAAATGATGTCTTAATGGTGTACCCAACTGTTAAATATGCTGTTCTTTATGCTACGAAAAATTATTTTAATGTATATCTTATGAACTTTAATTATGAGGCAGATGCTGATGTCTTGTCTGAACAAAATAAGAAATTAGTTGATTTCATTTTTGGGGAAAATGACCTAAATTACAATAAGAACAATGAAGCTATACAAAAATTAACAAATTTATTTAGCAATTTTATTAAATTAGGGTGA

Protein

MHGGILFILVVTATTVAGLELTIDDLLQQQSPELITDSTSSPRPDDGAISTPSGNMGSTDDVVTTTEVETTIKPSVTDENVSITTLRIETEAPTTGLTDRTESEAPSMEQNNLIETTHGLVRGFEWHTTGDIISYIDIPYAKYTKYFEEPKSSNAWETTHEVREHKSRCPQLQGESVVGSQDCLTLSIFAPTNAENVSVLFHIHESNFVQGSADPALYGPEYLVSKGLILVLPNYRLGPLGFLCLRNTMAPGNAALKDLSMALQWIKNNIAKFGGNPDTIVVSGEGTSGALIGFLALSSSSRNYFDKAITESGSVLSYWALDRNPALTGEKLTEALTKIDNSLNLETADILTILRAAQNIHFRPCIEKGNNPFMTQTPWGMIREQEVNITFMIGSANYAGLNEALDQNEASIEQLNDDFATLLPDDLAFGSDIERQNVVRNVRSQYFIENKPITLEDHIEGLSLCFTDSCFLGPAIRTARSLANAGAKVYFYEFSFTELISESHTVDRPVEGAVRGDIRNYVFTQDGRILTEGTAEREVVDIMVDTWFTFIENGNPVANETDWNRLTVTVPAQEEWMQLGPEIGLKQGLHLSRLNLWTNIYNNYFIEMRNNAPKPPPRWDGVFEATHRVKCPQLDIGDENCLVINIFTPEVSNNLPVLVHVHGGDYQNGWGFHQPPINLINKGIIIVTFNYRIGVLGFLCLGIPAAPGNVGLKDQVAALYWIQQNIKRFGGDPNDVTLYGTEAGSISIQLLLQARLMMGFHKVILESGSILSPTALTYNPIADAFAIGEQLGYNDTNNSHKLLKYLRKLSVTVLLDAHKISLPCVESVNNAESLIDKDPLQLLKDGPIDNIPMLVSYTRLKLRHNSEKLKTVPEDFVDLLPSNLEFTNDGIRYKISELIKDFYFFKDIDTSSSYENYLNDVLMVYPTVKYAVLYATKNYFNVYLMNFNYEADADVLSEQNKKLVDFIFGENDLNYNKNNEAIQKLTNLFSNFIKLG

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Uniprot

H9IU47   A0A0L7KU98   A0A194RI01   A0A194PGI6   A0A194PL79   A0A0L7L9I4   + More
A0A3S2TIN6   A0A2H1X3E8   A0A0L7L5N8   A0A0L7L1R0   A0A084VDQ2   A0A182WL96   B3NYP5   A0A1A9ZUL9   N6THW8   A0A195EV77   A0A1B0G6N0   A0A195B0I4   A0A336M3D7   A0A336M2B4   A0A232ET76   A0A0L0BN74   A0A2C9KB77   A0A182IXU7  

Pubmed

19121390    26227816    26354079    24438588    17994087    23537049    + More
28648823    26108605    15562597   

EMBL

BABH01034169    BABH01034170    JTDY01005778    KOB66636.1    KQ460205    KPJ17064.1    + More
KQ459604    KPI92143.1    KQ459602    KPI93489.1    JTDY01002125    KOB72049.1    RSAL01000111    RVE47056.1    ODYU01013095    SOQ59778.1    JTDY01002769    KOB70767.1    JTDY01003509    KOB69443.1    ATLV01011649    ATLV01011650    KE524705    KFB36096.1    CH954181    EDV48158.1    APGK01026030    APGK01026031    KB740612    ENN80004.1    KQ981965    KYN31797.1    CCAG010009612    KQ976691    KYM77971.1    UFQS01000292    UFQT01000292    SSX02543.1    SSX22917.1    UFQS01000360    UFQT01000360    SSX03135.1    SSX23501.1    NNAY01002318    OXU21558.1    JRES01001621    KNC21467.1   

Proteomes

UP000005204    UP000037510    UP000053240    UP000053268    UP000283053    UP000030765    + More
UP000075920    UP000008711    UP000092445    UP000019118    UP000078541    UP000092444    UP000078540    UP000215335    UP000037069    UP000076420    UP000075880   

PRIDE

H9IU47   

Pfam

PF00135   COesterase        + More
PF08238   Sel1

Interpro

IPR002018   CarbesteraseB        + More
IPR029058   AB_hydrolase       
IPR019826   Carboxylesterase_B_AS       
IPR019819   Carboxylesterase_B_CS       
IPR006597   Sel1-like       
IPR002168   Lipase_GDXG_HIS_AS       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9IU47   A0A0L7KU98   A0A194RI01   A0A194PGI6   A0A194PL79   A0A0L7L9I4   + More
A0A3S2TIN6   A0A2H1X3E8   A0A0L7L5N8   A0A0L7L1R0   A0A084VDQ2   A0A182WL96   B3NYP5   A0A1A9ZUL9   N6THW8   A0A195EV77   A0A1B0G6N0   A0A195B0I4   A0A336M3D7   A0A336M2B4   A0A232ET76   A0A0L0BN74   A0A2C9KB77   A0A182IXU7  

PDB

5TYM     E-value=5.90124e-38,     Score=399

KEGG

101737440    K12298 bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13] | (RefSeq) esterase FE4-like

PATHWAY

00100    Steroid biosynthesis - Bombyx mori (domestic silkworm)
00561    Glycerolipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016787   GO:0016021  

SignalP

Position:   1 - 18,         Likelihood:  0.985943

 

 

Length:

996

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.17451000000001

Exp number, first 60 AAs:

2.81012

Total prob of N-in:

0.14148

outside

1  -  996

 

 

Pi

206.273281

Theta

189.609769

Tajima's D

0.493782

CLR

0.56291

CSRT

0.514174291285436

Interpretation

Uncertain