Gene

KWMTBOMO14908

Pre Gene Modal

BGIBMGA000783

Annotation

PREDICTED:_protein_serrate_[Bombyx_mori]

Location

Bomo_Chr25(-):17975-29995      View in EpiBrowser

Full name

Delta-like protein      

Location in the cell

Extracellular   Reliability : 2.74

CDS

ATGCGGGCGCGGTGTGTGCGGCGCGCGCCGCTGCTGCTCCTCCTCGCCCTCGCCTGCACGCTGCGTTGCGCGGCGGGGGCGGGCGTGTTCGAGCTTCAAATACTGGAATTTAGCAACTATCGGCTGGAGGTGGGGGCGGGCGGATGCTGCGGGGGCGGCGGTCCGAGGGGCGCGGGAGCGGCGGCCTGCTCGCATCCCTGCCGCACCAGGTTTACGCTCTGCCTCAAGGAGTACCAGTCGGCGGCCGCGCCCGGCGGGAGCTGCTCCTTCGGGCGCGCCGCCTCCCCCGTCCTCGGCACTGACTCCTTCACTCTGGCTGAGCCTCTCTACACCCTCGCACTGCCCTTCAGCTTCCGATGGACGCGTTCGTTCACGTTGATCCTGCAGGCGTATGACGACTACGAATACTCCGAGCCCGAAGCGGGGCTCATCGAGGAGGCGTGGTGGTCCGGGATCGTGGAGCCGAGCGCGGAGTGGCACGCGCTGCGCCACGCGGGCGCCGCGGCTGCCGTCGCGTACCGCGTGCGGGTGCTCTGTCAGCCCAACTACTACAATACGACCTGCACCACGTTTTGCCGGCCCAGGGACGACAAGTTCGGCCACTACTCGTGCACGCCCGACGGCGACAAGCACTGCCTGCCGGGCTGGCAGGGGGACAACTGCGAGAAACCTGTTTGTAAGGAAGGCTGTCACCCGACTCACGGACGTTGCGATCGGCCCGGGGACTGCGATTGTCGACCGGGATGGAGAGGTGAACTGTGTTCTCAGTGTCAGCCGTATCCGGGGTGTAAACACGGCTACTGCAACGGTTCCTCCTGGGACTGCACCTGCGACACGAACTGGGGCGGGATACTTTGTGACCAAGATTTAAACTACTGCGGCACCCACGAGCCATGTCAGCACGGAGGCACCTGTGAGAACACCGCGCCGGATCAGTACTTCTGTCGGTGCGCCGAGGGCTTCTCCGGGGTGGACTGCGAGCGCGTCGACAACCCGTGCGCGCCGCAGCCCTGCGCTCATGGCACGTGCTCCCTCGCCGGCACGACGCGAGGCTTCACGTGCACGTGCGACCGCGGCTGGGGCGGGCTGCTCTGCGACACCGACCTCGACGACTGCGCCAGCGGGCCCTGCCTGCACGGCGCGTCCTGCAGGGACCACCTCGACGGCTTCACCTGCGAATGCGCAGACGGCTGGACCGGGCCAGCCTGCGCCGAAGACGTCGACGAGTGCTCGGGTCGAAGCATGACGGAGGGCGCGCTGGGTCCGTGCGTGAACGCGGCGGCCTGCAACAACACGGCGGGCGGGTACTCGTGCGCCTGTCTGGCGGGCTGGACCGGCCGGGACTGCGAGACCAACGTGGACGACTGCACGGGACAGTGCCTGCACGGCGCCACCTGCATCGACCTGGTGGACGACTTCCACTGCGCCTGCGCGGCGGGCTACGCGGGCCGCACGTGTTCGCTGGACGTGGACGACTGCGCCCCCCGCCCTTGCACCAACGGCGGCGAGTGCGTCGACCTGCTCAACGCTTACCGCTGCATCTGCCCCGTCGGCTTCTCCGGCACCAACTGCGAGGACGACCGCGACCACTGCGCCGGCTCTCCGTGCGGCAACGGCGCCGCCTGCTACACCGCGCAGAGCGACTACTACTGCCACTGCGCGCCCGGCTGGACCGGCAAGAACTGCACGCAGCGAGCTGCCAGGGACCAGGTGAGCCGCTGCAGCCCCAGCCCCTGCCGCAACAACGCCTCCTGCGTGGAGTCCGCTGCCGACGTCACCTGCGTGTGTCGCGACGGCTACACAGGTAAAACCTGCTCAGTACTTGTAGAAGAGAGCGAGCGCTGTGCGGAAGGAATGTGCGCGAACGGAGGCACTTGTGTGCGCGAGGAGGGGTCCTGGCGCTGTCTGTGCGCTGCGGGTTGGGGGGGCGGCGCCTGTGACTCCCTGCTGCCGCTCGCGCCCGCAGCTCCTCCGCCGTGCCCGTGCCAGGCGGGGGGGACGTGTCTGCCGTCCGCACTGCCTCCCGGCTGGGCTTGCGGGTGCAGAGAAGGTCGTACCGGAGCCTTGTGCGAACTGTCCCTGGATCTCTGTGGCTCTTCGCCTTGTCGTAACGGCGGTCGGTGCGTCGGTGGCTCGGGGTGGTGGATGTGCGAATGTGTGGCGGGCTGGACCGGAGAGACTTGTGCAGTGCGAGTGTCCGCCCCGCCCCTCCTGTGCTCCCCGCCCTGTCCCGCCCCCGCTGCCTGCGTCGCCGACCCCGCACGTCCCTCTTCCACCCGGTGTCTCTGTCCGGCGCCGCCGCAGCGTGCTGCTAGACGCTGCCTCGAGACTGTTGCCGGCTTGGAAGCAGAGGGCGATGACGTAGACGTTCTACAAAACGACAACCATGGAGTGTACAACCGACCAGACCCGAACGTGGGCGACGGACCGGGAGCGTGCGGCGTCGCTAACGGCACCTGGTGGTGGGGATGTAACGCATGTTGGTGTAGTGGGGGGGTGCCAACCTGCACTCGACTGTGGTGCGGCCTGCCGGACTGCCTAGCTCCTAACGCACAACCCTGCCGAACCGATGAAGTGTGTGTACCGGCGGCACCAGCACTGTGCTTGCGTGCTCCATGTGCCGCACTGGGGGAGTGCCGGCGGGTGTCTGGACGACGTGTGGAGCCCCCCGCCCTCCCGGCACCCCCCGCGTGCTGGCCGGGAGCCCGCTCCCCCGCTCCCCCCGCCCTCTGTGCTCGTGCTCAGCTGCAGCTCGCGAGGGAGCGGCTGGGACCGGGCGCGCACGTGGAGCGTGCCTGTGGAGCTCTGCGACGAGCGTTGGCTGCCGCTCTTGCCGTTCAAGACCCTCCGCCCCCACCACTGGCGTTACTTTGTGATCTCGCACCGGATGATGATGACGCCCTCGATCTCGCTTTGTGGATCGGAGACGAAGTGGGTTCAGACGGAGCCTCCGGTGCAGCGGCGCTTGGAACTGCAGTGCGGGCTCTCGGAGAGCTTGTGTCGCGTCGGCGGCTGGCCCGTCACGCCCTGCTCGGGGCAGTGCTGCGACTCCGCATGCCGCCAATAGCGCCGCCGGCCTCAGAGCCATCGACAGCGCCGGCGACCACTATCGCGGTCGGTCTACCGGTGGTGCTGCTAGTAGTGGCCGCGGCCATTGGCGCCTTCCTGTTCGTGCGGAGGAGACGTGTGGCGGCAGCGGAACGGTCACGGCGCTGCGACGAAGAGAAGTCTAACAACCTTCAAAACGAGGAGAACTTGCGGCGGTACGCAAACCCCCTGCGCGAGGAGCGTGGCGGGACCCGCGGCGAGGACCTGCCTCGGGCCCATTCGCTGTACAAGGCGCAGAACGCGGACGCGCGGAACGACACGCCGCCGCGGGACAAGGAGCTCACCCTCCGCGCCCTGCCGCCCCCCGAGCCGCCGCCCCCCGCGCGCCACCCGCCGCCCGAGCGACTCACTGTACTCGTGTGA

Protein

MRARCVRRAPLLLLLALACTLRCAAGAGVFELQILEFSNYRLEVGAGGCCGGGGPRGAGAAACSHPCRTRFTLCLKEYQSAAAPGGSCSFGRAASPVLGTDSFTLAEPLYTLALPFSFRWTRSFTLILQAYDDYEYSEPEAGLIEEAWWSGIVEPSAEWHALRHAGAAAAVAYRVRVLCQPNYYNTTCTTFCRPRDDKFGHYSCTPDGDKHCLPGWQGDNCEKPVCKEGCHPTHGRCDRPGDCDCRPGWRGELCSQCQPYPGCKHGYCNGSSWDCTCDTNWGGILCDQDLNYCGTHEPCQHGGTCENTAPDQYFCRCAEGFSGVDCERVDNPCAPQPCAHGTCSLAGTTRGFTCTCDRGWGGLLCDTDLDDCASGPCLHGASCRDHLDGFTCECADGWTGPACAEDVDECSGRSMTEGALGPCVNAAACNNTAGGYSCACLAGWTGRDCETNVDDCTGQCLHGATCIDLVDDFHCACAAGYAGRTCSLDVDDCAPRPCTNGGECVDLLNAYRCICPVGFSGTNCEDDRDHCAGSPCGNGAACYTAQSDYYCHCAPGWTGKNCTQRAARDQVSRCSPSPCRNNASCVESAADVTCVCRDGYTGKTCSVLVEESERCAEGMCANGGTCVREEGSWRCLCAAGWGGGACDSLLPLAPAAPPPCPCQAGGTCLPSALPPGWACGCREGRTGALCELSLDLCGSSPCRNGGRCVGGSGWWMCECVAGWTGETCAVRVSAPPLLCSPPCPAPAACVADPARPSSTRCLCPAPPQRAARRCLETVAGLEAEGDDVDVLQNDNHGVYNRPDPNVGDGPGACGVANGTWWWGCNACWCSGGVPTCTRLWCGLPDCLAPNAQPCRTDEVCVPAAPALCLRAPCAALGECRRVSGRRVEPPALPAPPACWPGARSPAPPALCARAQLQLARERLGPGAHVERACGALRRALAAALAVQDPPPPPLALLCDLAPDDDDALDLALWIGDEVGSDGASGAAALGTAVRALGELVSRRRLARHALLGAVLRLRMPPIAPPASEPSTAPATTIAVGLPVVLLVVAAAIGAFLFVRRRRVAAAERSRRCDEEKSNNLQNEENLRRYANPLREERGGTRGEDLPRAHSLYKAQNADARNDTPPRDKELTLRALPPPEPPPPARHPPPERLTVLV

Description

Putative Notch ligand involved in the mediation of Notch signaling.

Feature

chain  Delta-like protein

Uniprot

D5MTP3   H9IU53   A0A212EGY1   A0A3S2NP98   A0A2H1W4B0   A0A194PHG0   + More
A0A088AB52   A0A3L8D3C4   A0A0P5G595   A0A0P6FHQ5   A0A0P5YQ59   A0A0P6HRY5   A0A0P6AQ88   A0A0P6FP37   A0A0P5G192   A0A0P5LW75   A0A0P5XBJ3   A0A0P5HXM2   A0A0P6D7T9   A0A090AX49   A0A0N8B203   A0A0P6HK79   A0A0L7QMA8   E9GFT9   E2BHS1   K7J250   G3X2B1   A0A383YRF8  

Pubmed

22752911    19121390    22118469    26354079    30249741    21292972    + More
20798317    20075255    21709235   

EMBL

AB559580    BAJ07614.2    BABH01034140    BABH01034141    BABH01034142    AGBW02014998    + More
OWR40736.1    RSAL01000958    RVE41021.1    ODYU01006226    SOQ47878.1    KQ459604    KPI92149.1    QOIP01000014    RLU14890.1    GDIQ01250877    JAK00848.1    GDIQ01048253    JAN46484.1    GDIP01055330    JAM48385.1    GDIQ01030609    JAN64128.1    GDIP01026444    JAM77271.1    GDIQ01044743    JAN49994.1    GDIQ01248130    GDIQ01248129    GDIQ01248128    GDIQ01229874    JAK03596.1    GDIQ01198394    GDIQ01164297    GDIQ01164296    GDIQ01132865    GDIQ01132864    GDIQ01098571    JAK87428.1    GDIP01074481    JAM29234.1    GDIQ01221530    JAK30195.1    GDIQ01089328    JAN05409.1    AB851456    BAP63965.1    GDIQ01220635    JAK31090.1    GDIQ01018921    JAN75816.1    KQ414894    KOC59684.1    GL732542    EFX81699.1    GL448324    EFN84754.1    AEFK01030049    AEFK01030050    AEFK01030051   

Proteomes

UP000005204    UP000007151    UP000283053    UP000053268    UP000005203    UP000279307    + More
UP000053825    UP000000305    UP000008237    UP000002358    UP000007648   

PRIDE

D5MTP3    H9IU53   

Pfam

PF12661   hEGF        + More
PF07657   MNNL
PF00008   EGF
PF01414   DSL
PF07645   EGF_CA

Interpro

IPR000152   EGF-type_Asp/Asn_hydroxyl_site        + More
IPR000742   EGF-like_dom       
IPR018097   EGF_Ca-bd_CS       
IPR013032   EGF-like_CS       
IPR026219   Jagged/Serrate       
IPR009030   Growth_fac_rcpt_cys_sf       
IPR001774   DSL       
IPR011651   Notch_ligand_N       
IPR001881   EGF-like_Ca-bd_dom       
IPR001007   VWF_dom       
IPR033108   Jag2       

SUPFAM

SSF57184   SSF57184       

ProteinModelPortal

D5MTP3   H9IU53   A0A212EGY1   A0A3S2NP98   A0A2H1W4B0   A0A194PHG0   + More
A0A088AB52   A0A3L8D3C4   A0A0P5G595   A0A0P6FHQ5   A0A0P5YQ59   A0A0P6HRY5   A0A0P6AQ88   A0A0P6FP37   A0A0P5G192   A0A0P5LW75   A0A0P5XBJ3   A0A0P5HXM2   A0A0P6D7T9   A0A090AX49   A0A0N8B203   A0A0P6HK79   A0A0L7QMA8   E9GFT9   E2BHS1   K7J250   G3X2B1   A0A383YRF8  

PDB

4XBM     E-value=1.18461e-81,     Score=777

KEGG

101737017    K06052 jagged-1 | (RefSeq) protein serrate

PATHWAY

04330    Notch signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0007219   GO:0005509   GO:0005112   GO:0016021   GO:0007275   GO:0005886   GO:0045746   GO:0005515   GO:0016705   GO:0007154   GO:0016020   GO:0015930  

PANTHER

PTHR24049:SF18  

Subcellular location

Membrane  

SignalP

Position:   1 - 26,         Likelihood:  0.994418

 

 

Length:

1156

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

43.54429

Exp number, first 60 AAs:

20.82603

Total prob of N-in:

0.94975

POSSIBLE N-term signal

sequence

inside

1  -  11

TMhelix

12  -  34

outside

35  -  1035

TMhelix

1036  -  1058

inside

1059  -  1156

 

 

Pi

303.639936

Theta

232.033685

Tajima's D

0.749953

CLR

0.429209

CSRT

0.592620368981551

Interpretation

Uncertain