Gene

KWMTBOMO14887  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012182

Annotation

PREDICTED:_T-complex_protein_1_subunit_eta_isoform_X2_[Papilio_xuthus]

Location

Bomo_Chr24(-):17097716-17111810      View in EpiBrowser

Full name

T-complex protein 1 subunit eta      

Alternative Name

CCT-eta

Location in the cell

Cytoplasmic   Reliability : 3.352

CDS

ATGCAACCGCAAATACTTTTACTGAGAGAGGGAACGGACCAGACGCAGGGCAAGCCCCAGCTCGTCTCCAACATCAATGCCTGTCAACTTGTTGTCGATGCGGTCAGAACCACCCTGGGTCCCCGTGGTATGGACAAGCTGATTGTAGATCACAATGGAAAGGCGGTTATATCAAACGATGGTGCAACGATCATGAAGCTACTGGATATCATTCACCCTGCCGCTAAAACTCTTGTGGATATTGCAAAGTCTCAAGATGCCGAGGTTGGCGATGGAACCACCTCGGTAGTGATATTGGCCGGTGAAATTCTGAAGAGGTTGAAGCCGTTTGTTGAAGAAGGTGTTCACCCTCGTGTTCTGATCAGAGCAGTCAGAACAGCGTCAAGACTGGCCATTGAGAAAATCAAGGAGCAAGCTGTGAAAATTGATAATAAGTCGCCTGAGGAACAAAGAGATCTCCTATTGAAGTGTGCATCAACAGCGATGTCATCGAAACTGATTCATCAACAGAAGGATCACTTCTCTAAGATTGTTGTTGATGCTGTCCTGTCTTTGGACACTCCACTTCTGCCTCTCGACATGATTGGAATCAAGAAGGTTCCCGGTGGAGCTCTTGAAGATTCGTTCCTGGTTCCCGGAGTGGCGTTCAAGAAAACTTTCAGTTACGCTGGCTTTGAGATGCAGCCGAAGACATACAAAGACTGCAAGATCGCACTCCTCAATATTGAGCTGGAATTGAAAGCTGAAAGAGACAATGCCGAGGTTCGAGTAAACAACGTGAGGGAATATCAGAAGGTGGTGGATGCTGAGTGGCAGATCTTATACGAGAAGCTCGCCGCTTTGCATGCTAGCGGAGCAAATGTGGTCCTCAGCAAGCTGCCCATCGGAGATGTTGCCACACAATACTTTGCGGACCGAGATATGTTCTGCGCTGGACGAGTGCCCGAGGAAGACATGCGGCGTACGGCGCGCGCTTGCGGGGGAGCCGTACTCGCCTCAACGAGGGACCTCACGCCTCAAGTTCTAGGTCACACGGCGCTCTTCACGGAGAAACAGCTTGGAGCTGACAGATACAACTTCTTTACTGGCTGTCCGGGTGCCAAGACATGTACATTGATCCTGCGAGGTGGTGCGGAACAGTTCTTGGAGGAGACGGAGCGTTCCCTGCACGATGCCATCATGATAGTCCGGAGAACGATCAAGAATGATGCTGTAGTGGCTGGCGGAGGAGCAGTAGACATGCAAATCTCTGCCCATCTCCGGTCTCACTCTCTACAACTGGCTGGCAAGGAGCAGTTGGCTGTAGCGGCAGTGGCCCGAGCCTTTGAGGCCATCCCTCGTCAGCTGGCAGACAATGCAGGCCTGGACGGGACCGGACTCCTCAATAAACTAAGGCAGAAGCACGCCGCTGGGGAGCACACGCACGGTGTGGACGTTATCAGTGGAGAGGTGGTGGATAACTTTGCGAAGTGCGTGTGGGAGCCGGCCCTCGTCAAGCTTAACGCCGTGAGTGCCGCCTGCGAGGCCACCGCTCAGATTCTATCAGTGGATGAGACCATCAAGAATGTCAAGGGCGGTGAAGAGGCGCAGATGCCTGGTCGCGGCATGGGCCGCCCTCGTATGGGATAG

Protein

MQPQILLLREGTDQTQGKPQLVSNINACQLVVDAVRTTLGPRGMDKLIVDHNGKAVISNDGATIMKLLDIIHPAAKTLVDIAKSQDAEVGDGTTSVVILAGEILKRLKPFVEEGVHPRVLIRAVRTASRLAIEKIKEQAVKIDNKSPEEQRDLLLKCASTAMSSKLIHQQKDHFSKIVVDAVLSLDTPLLPLDMIGIKKVPGGALEDSFLVPGVAFKKTFSYAGFEMQPKTYKDCKIALLNIELELKAERDNAEVRVNNVREYQKVVDAEWQILYEKLAALHASGANVVLSKLPIGDVATQYFADRDMFCAGRVPEEDMRRTARACGGAVLASTRDLTPQVLGHTALFTEKQLGADRYNFFTGCPGAKTCTLILRGGAEQFLEETERSLHDAIMIVRRTIKNDAVVAGGGAVDMQISAHLRSHSLQLAGKEQLAVAAVARAFEAIPRQLADNAGLDGTGLLNKLRQKHAAGEHTHGVDVISGEVVDNFAKCVWEPALVKLNAVSAACEATAQILSVDETIKNVKGGEEAQMPGRGMGRPRMG

Description

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

Subunit

Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

Similarity

Belongs to the TCP-1 chaperonin family.

Uniprot

H9JRM2   A0A2A4KB20   A0A212EJW0   A0A0N1I5L4   A0A0L0C7B5   A0A1L8DUA7   + More
U5EYW9   A0A1Y9H2B3   A0A0A1WZV3   A0A182F992   A0A2M3ZGM4   W8B7A3   B4KDM5   A0A182Y3V9   W5JAM7   A0A034VMZ5   A0A2M4A661   A0A2M4BJF5   T1DGV8   A0A182UQ34   T1PDA9   A0A182U284   A0A182XIU0   Q7PGM0   A0A182VZP9   A0A1B6LLS6   A0A182HTH9   A0A182QWQ4   A0A084VWM2   A0A0K8WKZ7   A0A182P504   A0A1L8ECI8   B4LWV7   A0A1B6F0B1   A0A182JW05   A0A1I8NV51   B3LXX7   A0A232F081   A0A1Q3F8H6   Q9VHL2   A0A182M116   A0A023EUT4   A0A1W4W2H7   B4NB31   A0A1B0CJ02   A0A336LHQ7   Q17P27   E0V947   A0A1B6CDI9   B4PTW7   B3P4R8   D3TLV7   A0A182J8C4   A0A0M3QYN8   A0A0A9Y855   A0A1W4X638   B0WFH0   A0A182RSY3   A0A1Y1K9S1   A0A1J1IYW5   A0A3B0JP67   D0QWN5   J3JWM9   Q294I9   A0A0P6IC77   A0A164VFC7   B4GL19   E9FX08   A0A023F4G7   A0A0V0G3V3   A0A0P6AN96   A0A069DV50   A0A0P5BTH5   A0A224XHV4   V5G6I1   A0A151J6G8   A0A0P4VTR7   A0A1S3I1C0   D6WBZ5   T1IDR0   A0A385L3J3   J9PNK3   V5RDK5   A0A195FJ69   A0A026W0P5   A0A0P4WFK2   A0A195C9J2   F4WX99   A0A151WMY4   A0A3L8DNN7   A0A158NU49   A0A2J7PBY2   A0A1B6ENH8   T1FNQ7   Q95V46   A0A0P5B6L9   E2B249   E9IQ54   A0A0J7L5X5   A0A293LGP1  

Pubmed

19121390    22118469    26354079    26108605    25830018    24495485    + More
17994087    25244985    20920257    23761445    25348373    12364791    14747013    17210077    24438588    28648823    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24945155    26483478    17510324    20566863    17550304    20353571    25401762    26823975    28004739    19859648    22516182    23537049    15632085    21292972    25474469    26334808    27129103    18362917    19820115    22903032    24508170    21719571    30249741    21347285    23254933    20798317    21282665   

EMBL

BABH01031739    NWSH01000005    PCG80993.1    AGBW02014393    OWR41761.1    KQ458863    + More
KPJ04730.1    JRES01000819    KNC28136.1    GFDF01004063    JAV10021.1    GANO01001768    JAB58103.1    GBXI01010374    JAD03918.1    GGFM01006892    MBW27643.1    GAMC01009490    JAB97065.1    CH933806    EDW13859.1    ADMH02002035    ETN59839.1    GAKP01014276    JAC44676.1    GGFK01002899    MBW36220.1    GGFJ01004065    MBW53206.1    GAMD01002616    JAA98974.1    KA645918    KM215141    AFP60547.1    AIU39614.1    AAAB01008859    EAA44880.4    GEBQ01015285    JAT24692.1    APCN01000533    AXCN02000034    ATLV01017659    ATLV01017660    ATLV01017661    KE525181    KFB42366.1    GDHF01000476    JAI51838.1    GFDG01002341    JAV16458.1    CH940650    EDW66678.1    GECZ01026164    JAS43605.1    CH902617    EDV42833.1    NNAY01001420    OXU24035.1    GFDL01011199    JAV23846.1    AE014297    AY122201    AAF54292.2    AAM52713.1    AXCM01000485    JXUM01138996    JXUM01138997    JXUM01138998    GAPW01000856    KQ568825    JAC12742.1    KXJ68873.1    CH964232    EDW80995.1    AJWK01013934    AJWK01013935    AJWK01013936    AJWK01013937    UFQS01000011    UFQT01000011    SSW97178.1    SSX17564.1    CH477194    EAT48473.1    DS234988    EEB09903.1    GEDC01025784    JAS11514.1    CM000160    EDW96578.2    CH954181    EDV49862.1    CCAG010001926    CCAG010001927    CCAG010001928    EZ422409    ADD18685.1    CP012526    ALC48003.1    GBHO01015250    GBRD01014563    GDHC01011610    JAG28354.1    JAG51263.1    JAQ07019.1    DS231918    EDS26238.1    GEZM01092928    JAV56425.1    CVRI01000064    CRL05343.1    OUUW01000008    SPP84024.1    FJ821033    ACN94734.1    BT127647    KB632375    AEE62609.1    ERL93864.1    CM000070    EAL28975.2    GDIQ01006672    JAN88065.1    LRGB01001361    KZS12267.1    CH479185    EDW38243.1    GL732526    EFX87987.1    GBBI01002287    JAC16425.1    GECL01003477    JAP02647.1    GDIP01032593    JAM71122.1    GBGD01001089    JAC87800.1    GDIP01184479    JAJ38923.1    GFTR01007038    JAW09388.1    GALX01002776    JAB65690.1    KQ979854    KYN18814.1    GDKW01001223    JAI55372.1    KQ971309    EEZ99111.1    ACPB03005390    MH492355    AYA22349.1    HQ668094    AET34921.1    KF621129    AHB33465.1    KQ981522    KYN40705.1    KK107503    EZA49598.1    GDRN01052970    JAI66213.1    KQ978143    KYM96783.1    GL888423    EGI61148.1    KQ982926    KYQ49234.1    QOIP01000006    RLU21896.1    ADTU01026217    NEVH01027073    PNF13845.1    GECZ01030291    JAS39478.1    AMQM01007697    KB097656    ESN92287.1    AF427597    AAL27405.1    GDIP01188779    JAJ34623.1    GL445059    EFN60224.1    GL764659    EFZ17306.1    LBMM01000647    KMQ97894.1    GFWV01002299    MAA27029.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000037069    UP000075884    + More
UP000069272    UP000009192    UP000076408    UP000000673    UP000075903    UP000075902    UP000076407    UP000007062    UP000075920    UP000075840    UP000075886    UP000030765    UP000075885    UP000008792    UP000075881    UP000095300    UP000007801    UP000215335    UP000000803    UP000075883    UP000069940    UP000249989    UP000192221    UP000007798    UP000092461    UP000008820    UP000009046    UP000002282    UP000008711    UP000092444    UP000075880    UP000092553    UP000192223    UP000002320    UP000075900    UP000183832    UP000268350    UP000030742    UP000001819    UP000076858    UP000008744    UP000000305    UP000078492    UP000085678    UP000007266    UP000015103    UP000078541    UP000053097    UP000078542    UP000007755    UP000075809    UP000279307    UP000005205    UP000235965    UP000015101    UP000000311    UP000036403   

PRIDE

H9JRM2   

Pfam

PF00118   Cpn60_TCP1        + More
PF02944   BESS
PF00147   Fibrinogen_C

Interpro

IPR027409   GroEL-like_apical_dom_sf        + More
IPR027413   GROEL-like_equatorial_sf       
IPR002194   Chaperonin_TCP-1_CS       
IPR012720   Chap_CCT_eta       
IPR017998   Chaperone_TCP-1       
IPR027410   TCP-1-like_intermed_sf       
IPR002423   Cpn60/TCP-1       
IPR004210   BESS_motif       
IPR006578   MADF-dom       
IPR019594   Glu/Gly-bd       
IPR036056   Fibrinogen-like_C       
IPR014715   Fibrinogen_a/b/g_C_2       
IPR014716   Fibrinogen_a/b/g_C_1       
IPR002181   Fibrinogen_a/b/g_C_dom       
IPR020837   Fibrinogen_CS       

SUPFAM

SSF48592   SSF48592        + More
SSF54849   SSF54849       
SSF52029   SSF52029       
SSF56496   SSF56496       

Gene 3D

1.10.560.10     3.30.260.10     3.50.7.10     3.90.215.10     4.10.530.10    

CDD

cd03340  TCP1_eta
cd00087  FReD

ProteinModelPortal

H9JRM2   A0A2A4KB20   A0A212EJW0   A0A0N1I5L4   A0A0L0C7B5   A0A1L8DUA7   + More
U5EYW9   A0A1Y9H2B3   A0A0A1WZV3   A0A182F992   A0A2M3ZGM4   W8B7A3   B4KDM5   A0A182Y3V9   W5JAM7   A0A034VMZ5   A0A2M4A661   A0A2M4BJF5   T1DGV8   A0A182UQ34   T1PDA9   A0A182U284   A0A182XIU0   Q7PGM0   A0A182VZP9   A0A1B6LLS6   A0A182HTH9   A0A182QWQ4   A0A084VWM2   A0A0K8WKZ7   A0A182P504   A0A1L8ECI8   B4LWV7   A0A1B6F0B1   A0A182JW05   A0A1I8NV51   B3LXX7   A0A232F081   A0A1Q3F8H6   Q9VHL2   A0A182M116   A0A023EUT4   A0A1W4W2H7   B4NB31   A0A1B0CJ02   A0A336LHQ7   Q17P27   E0V947   A0A1B6CDI9   B4PTW7   B3P4R8   D3TLV7   A0A182J8C4   A0A0M3QYN8   A0A0A9Y855   A0A1W4X638   B0WFH0   A0A182RSY3   A0A1Y1K9S1   A0A1J1IYW5   A0A3B0JP67   D0QWN5   J3JWM9   Q294I9   A0A0P6IC77   A0A164VFC7   B4GL19   E9FX08   A0A023F4G7   A0A0V0G3V3   A0A0P6AN96   A0A069DV50   A0A0P5BTH5   A0A224XHV4   V5G6I1   A0A151J6G8   A0A0P4VTR7   A0A1S3I1C0   D6WBZ5   T1IDR0   A0A385L3J3   J9PNK3   V5RDK5   A0A195FJ69   A0A026W0P5   A0A0P4WFK2   A0A195C9J2   F4WX99   A0A151WMY4   A0A3L8DNN7   A0A158NU49   A0A2J7PBY2   A0A1B6ENH8   T1FNQ7   Q95V46   A0A0P5B6L9   E2B249   E9IQ54   A0A0J7L5X5   A0A293LGP1  

PDB

4B2T     E-value=0,     Score=1814

KEGG

101735319    K09499 T-complex protein 1 subunit eta | (RefSeq) T-complex protein 1 subunit eta

GO

GO:0051082   GO:0005524   GO:0006457   GO:0005737   GO:0003677   GO:0005634   GO:0005832   GO:0004970   GO:0016021   GO:0005829   GO:0003676   GO:0016701   GO:0006355   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR11353:SF22  

Subcellular location

Cytoplasm  
Nucleus  

Length:

542

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0038

Exp number, first 60 AAs:

0.00266

Total prob of N-in:

0.00070

outside

1  -  542

 

 

Pi

227.310728

Theta

159.67381

Tajima's D

1.934459

CLR

0.157258

CSRT

0.869306534673266

Interpretation

Uncertain