Gene

KWMTBOMO14848  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012193

Annotation

PREDICTED:_glycerol-3-phosphate_acyltransferase_4_isoform_X3_[Papilio_xuthus]

Location

Bomo_Chr24(-):16291522-16297590      View in EpiBrowser

Full name

Glycerol-3-phosphate acyltransferase 3      

Alternative Name

1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9
Acyl-CoA:glycerol-3-phosphate acyltransferase 3
Lysophosphatidic acid acyltransferase theta

Location in the cell

Mitochondrial   Reliability : 1.442 PlasmaMembrane   Reliability : 1.555

CDS

ATGATAATCACAACGACGCTGGTCAGCACGCTACCGTCTGGTAGGGTGAGGCGTTACCTCGGCGCTGTCTCCTACAAAATCTCCATCCGCGTACTGATAAGGAGTCTGTCGTGCGTGATAACGTTCCACGACCAGCAGCACATGCCGAAATCGAACGGCTTCTGTGTCGCCAATCACACGAGCCCGATCGATGTGGCCATCGTCAGCGTGAACACGTGCTTCTCATTGATTGGACAGAGGCACGGAGGATTCCTCGGTCTCCTACAGAGGGCTCTCGCGAGGGCGTCCCCTCACATTTGGTTCGAGAGGTCGGAGGTTAAAGACAGGCACGCCGTCGCGAGGAGACTAAAAGAACACATATCGGTTGCCGACAATCCTCCTATACTGATATTTCCCGAAGGCACCTGCATAAATAACACGTCGGTGATGCAGTTCAAGAAGGGCAGCTTCGAAGTCGGCGGCACTGTCTACCCAGTGGCAATCAAGTGA

Protein

MIITTTLVSTLPSGRVRRYLGAVSYKISIRVLIRSLSCVITFHDQQHMPKSNGFCVANHTSPIDVAIVSVNTCFSLIGQRHGGFLGLLQRALARASPHIWFERSEVKDRHAVARRLKEHISVADNPPILIFPEGTCINNTSVMQFKKGSFEVGGTVYPVAIK

Description

May transfer the acyl-group from acyl-coA to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Also transfers the acyl-group from acyl-coA to the sn-2 position of 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid, or LPA), forming 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid, or PA).

Catalytic Activity

an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA
a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA

Similarity

Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Keywords

Acyltransferase   Complete proteome   Endoplasmic reticulum   Lipid biosynthesis   Lipid metabolism   Membrane   Phospholipid biosynthesis   Phospholipid metabolism   Phosphoprotein   Reference proteome   Transferase   Transmembrane   Transmembrane helix  

Feature

chain  Glycerol-3-phosphate acyltransferase 3

Uniprot

A0A2A4J561   A0A1E1W253   W8C971   A0A0A1X8M2   A0A0K8V513   A0A2A4J4L5   + More
A0A0L7LGZ1   A0A0K8UU81   A0A1L8EDX2   A0A1L8EDT9   V5GTI7   A0A291P138   A0A291P129   V5GHQ3   A0A2W1BJQ5   A0A1I8M243   A0A2J7PWA8   A0A1I8Q8N5   A0A0R3NTV1   A0A3B0J2H0   A0A1Y1LA95   A0A0N1IAB6   A0A0P0EA76   A0A1V0M890   A0A088M9A3   A0A194Q131   A0A0Q9X8X4   Q9W1B5   B4PAT5   A0A0J9RK61   B3NQ72   A0A1W4UMC0   B3MDX1   A0A1W4XCD5   A0A0C9QPY2   B4LPD3   A0A3S2N4Q7   A0A1L8DY55   W5J2T7   A0A212F2Q5   A0A1B6ECR7   A0A1L8DYS0   A0A2P8YTM3   E0VSI7   A0A1B6HSN4   A0A1Y1LAC1   A0A1Y1LG56   A0A0C9QCN7   A0A1W7R898   A0A224XPG7   A0A154PMK4   A0A1B0FK30   A0A1B0C1H5   A0A067QT47   A0A2J7PWA6   A0A1B6GNX9   A0A1A9VKM6   A0A0L7QVJ6   A0A023ET90   A0A232FLL4   A0A1A9XAC6   K7IT41   A0A1A9ZVJ6   A0A0V0G3F7   D6WBN5   T1IW46   A0A0U3BIT0   A0A060YX47   A0A0M9ACA5   T1HC21   A0A1S4EVW1   G1KKZ9   A0A2D4KFS3   A0A0T6AZD4   U3FCN4   E2A055   T1P9H1   A0A2A3EJP6   A0A088AGA7   A0A182GZ08   A0A1Q3FVU1   A0A250YI92   A0A1Q3FVT2   B0W6P5   A0A151P208   A0A0B8RXL7   A0A1U7SBP5   A0A3L8DI46   A0A0J7L5L0   G3IK30   A0A1Q3FW83   A0A1Y1LF29   A0A1Q3FVT1   A0A1Q3FVU0   A0A1Q3FWB7   Q17P93   A0A146KKN9   A0A1S3FHJ5   K7GAT1   Q8C0N2  

EC Number

2.3.1.15

Pubmed

24495485    25830018    26227816    28986331    28756777    25315136    + More
15632085    17994087    28004739    26354079    26445454    28349297    26385554    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    22936249    20920257    23761445    22118469    29403074    20566863    24845553    24945155    28648823    20075255    18362917    19820115    24755649    23915248    20798317    26483478    28087693    22293439    25476704    30249741    21804562    17510324    26823975    17381049    16141072    15489334    17170135    17242355    18630941    19144319    21183079   

EMBL

NWSH01003180    PCG66818.1    GDQN01010040    JAT81014.1    GAMC01006896    JAB99659.1    + More
GBXI01006638    JAD07654.1    GDHF01018292    JAI34022.1    PCG66819.1    JTDY01001227    KOB74476.1    GDHF01022226    JAI30088.1    GFDG01001933    JAV16866.1    GFDG01001932    JAV16867.1    GALX01004913    JAB63553.1    MF706175    ATJ44602.1    MF687643    ATJ44569.1    GALX01004912    JAB63554.1    KZ150102    PZC73497.1    NEVH01020936    PNF20613.1    CM000071    KRT02243.1    OUUW01000001    SPP73233.1    GEZM01061280    JAV70572.1    KQ460396    KPJ15331.1    KT261717    ALJ30257.1    KU755496    ARD71206.1    KJ579236    AIN34712.1    KQ459580    KPI99261.1    CH933808    KRG04891.1    AE013599    BT072873    AAF47157.2    ACN63495.1    CM000158    EDW92475.2    CM002911    KMY96251.1    CH954179    EDV56945.2    CH902619    EDV37516.2    GBYB01005709    JAG75476.1    CH940648    EDW61192.2    RSAL01000568    RVE41378.1    GFDF01002738    JAV11346.1    ADMH02002129    ETN58607.1    AGBW02010693    OWR48025.1    GEDC01001611    JAS35687.1    GFDF01002642    JAV11442.1    PYGN01000366    PSN47586.1    DS235751    EEB16343.1    GECU01030036    JAS77670.1    GEZM01061279    JAV70574.1    GEZM01061277    JAV70576.1    GBYB01012183    JAG81950.1    GEHC01000271    JAV47374.1    GFTR01006373    JAW10053.1    KQ434980    KZC13082.1    CCAG010017210    JXJN01024053    KK852969    KDR13114.1    PNF20614.1    GECZ01005635    JAS64134.1    KQ414726    KOC62640.1    GAPW01001058    JAC12540.1    NNAY01000061    OXU31399.1    AAZX01006711    GECL01003497    JAP02627.1    KQ971311    EEZ98897.2    JH431607    KT328600    ALT07197.1    FR925089    CDQ96306.1    KQ435706    KOX80219.1    ACPB03008412    ACPB03008413    ACPB03008414    IACL01056014    LAB07571.1    LJIG01022464    KRT80440.1    GAEP01000617    JAB54204.1    GL435551    EFN73188.1    KA644810    AFP59439.1    KZ288235    PBC31406.1    JXUM01021838    JXUM01021839    JXUM01021840    JXUM01021841    JXUM01021842    JXUM01021843    KQ560612    KXJ81628.1    GFDL01003326    JAV31719.1    GFFW01001522    JAV43266.1    GFDL01003324    JAV31721.1    DS231849    EDS36876.1    AKHW03001358    KYO42735.1    GBSH01001173    JAG67852.1    QOIP01000007    RLU19996.1    LBMM01000472    KMQ98257.1    JH003478    EGW11247.1    GFDL01003319    JAV31726.1    GEZM01061278    JAV70575.1    GFDL01003331    JAV31714.1    GFDL01003321    JAV31724.1    GFDL01003332    JAV31713.1    CH477193    EAT48539.1    GDHC01021940    JAP96688.1    AGCU01005067    AGCU01005068    AGCU01005069    AGCU01005070    AGCU01005071    AK030171    AK160261    AK138410    BC096769    BC138228    BC145669   

Proteomes

UP000218220    UP000037510    UP000095301    UP000235965    UP000095300    UP000001819    + More
UP000268350    UP000053240    UP000053268    UP000009192    UP000000803    UP000002282    UP000008711    UP000192221    UP000007801    UP000192223    UP000008792    UP000283053    UP000000673    UP000007151    UP000245037    UP000009046    UP000076502    UP000092444    UP000092460    UP000027135    UP000078200    UP000053825    UP000215335    UP000092443    UP000002358    UP000092445    UP000007266    UP000193380    UP000053105    UP000015103    UP000001646    UP000000311    UP000242457    UP000005203    UP000069940    UP000249989    UP000002320    UP000050525    UP000189705    UP000279307    UP000036403    UP000001075    UP000008820    UP000081671    UP000007267    UP000000589   

PRIDE

Q9W1B5    G3IK30    Q8C0N2   

Pfam

PF01553   Acyltransferase

Interpro

IPR002123   Plipid/glycerol_acylTrfase       

ProteinModelPortal

A0A2A4J561   A0A1E1W253   W8C971   A0A0A1X8M2   A0A0K8V513   A0A2A4J4L5   + More
A0A0L7LGZ1   A0A0K8UU81   A0A1L8EDX2   A0A1L8EDT9   V5GTI7   A0A291P138   A0A291P129   V5GHQ3   A0A2W1BJQ5   A0A1I8M243   A0A2J7PWA8   A0A1I8Q8N5   A0A0R3NTV1   A0A3B0J2H0   A0A1Y1LA95   A0A0N1IAB6   A0A0P0EA76   A0A1V0M890   A0A088M9A3   A0A194Q131   A0A0Q9X8X4   Q9W1B5   B4PAT5   A0A0J9RK61   B3NQ72   A0A1W4UMC0   B3MDX1   A0A1W4XCD5   A0A0C9QPY2   B4LPD3   A0A3S2N4Q7   A0A1L8DY55   W5J2T7   A0A212F2Q5   A0A1B6ECR7   A0A1L8DYS0   A0A2P8YTM3   E0VSI7   A0A1B6HSN4   A0A1Y1LAC1   A0A1Y1LG56   A0A0C9QCN7   A0A1W7R898   A0A224XPG7   A0A154PMK4   A0A1B0FK30   A0A1B0C1H5   A0A067QT47   A0A2J7PWA6   A0A1B6GNX9   A0A1A9VKM6   A0A0L7QVJ6   A0A023ET90   A0A232FLL4   A0A1A9XAC6   K7IT41   A0A1A9ZVJ6   A0A0V0G3F7   D6WBN5   T1IW46   A0A0U3BIT0   A0A060YX47   A0A0M9ACA5   T1HC21   A0A1S4EVW1   G1KKZ9   A0A2D4KFS3   A0A0T6AZD4   U3FCN4   E2A055   T1P9H1   A0A2A3EJP6   A0A088AGA7   A0A182GZ08   A0A1Q3FVU1   A0A250YI92   A0A1Q3FVT2   B0W6P5   A0A151P208   A0A0B8RXL7   A0A1U7SBP5   A0A3L8DI46   A0A0J7L5L0   G3IK30   A0A1Q3FW83   A0A1Y1LF29   A0A1Q3FVT1   A0A1Q3FVU0   A0A1Q3FWB7   Q17P93   A0A146KKN9   A0A1S3FHJ5   K7GAT1   Q8C0N2  

PDB

5KYM     E-value=0.042898,     Score=81

KEGG

101736437    K13506 glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] | (RefSeq) glycerol-3-phosphate acyl

GO

GO:0016746   GO:0016021   GO:0012505   GO:0102420   GO:0004366   GO:0005789   GO:0019432   GO:0032006   GO:0003841   GO:0005783   GO:0016024   GO:0008152   GO:0006396   GO:0006508   GO:0016701   GO:0006355   GO:0003824   GO:0016491   GO:0015930  

Subcellular location

Endoplasmic reticulum membrane  

Length:

162

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.28611

Exp number, first 60 AAs:

0.18551

Total prob of N-in:

0.18761

outside

1  -  162

 

 

Pi

295.179009

Theta

211.616803

Tajima's D

0.72689

CLR

120.617031

CSRT

0.584220788960552

Interpretation

Uncertain