Gene

KWMTBOMO14788  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012217

Annotation

hemolymph_protein_14_[Bombyx_mori]

Location

Bomo_Chr24(+):15110826-15126065      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 4.103

CDS

ATGTCCAGATGCCAGAGCAATTGGTTCCGCTGTACGTATGGCGCGTGCGTGGATGGTACGGCGCCCTGCAACGGAATCCAGGAGTGCGCCGATAACTCTGATGAGCTGCTACCTCAGTGTCGGGGGAATGAGGTCGCGGACGCGACGAACTTGAGAGACAAGTTCAAGTGTGCTGACGGTAACGTTATACCGGCCACCGCGTTCTGTGACGGCGTAGCCGACTGCCCGGACGGGTCTGACGAGACGGTCCAGGCGTGCGCGGGCAGGACGTGCCCGGCGTACTTGTTCCAGTGCGCGTATGGAGCTTGCGTAGACGCCGGATCAGACTGTAACGGGATAAAAGAATGCGCTGACGGCTCGGATGAGTCGGACGAGCTCTGTGATAGAGTCCTGTCCGGGAAGCCGACGCAAAAGCCTTCAGCATCAGGCGGATGCGTCCTGCCCCAGTACCCAGCTCACGGCTCGTACGTGGTCCTGAACACGCCGAACGCTACTCCCGGCCAGACCTTCGACTCGATCCAAGTGAACGTGACCTGCAAGCCGGGGTACGGCGTGATGGGCAGGAACGACGTCTTCTGCTTGAACGGGTGGTGGTCGGACAAGCTGCCTCAGTGCGTCCGTTTCTGCACGCTCAACAGTCATGCTAGCGTCGAGTACAAATGTCTGCTCACCAATGGTAACGAGGGTACCAGACCCTGCGGCTCCCTGGAGCCGACCGGCACAATAGTCCAGCCGCAGTGCAGGTCCCCCAACTATTACTCGACCGTGCCGCTCGGCTACATGCGGTGCATCGAGGGGAACTGGGACTACGTGGCCACATGCACTCCAGAATGCGGCAGAGTCACGCCTGACGGTGAAGAGTTGGTGTTCGGCGGGAGATCAGCGAAAAGAGGAGAACTACCCTGGCATGCTGGCATATATAGGAAGACTAGCACACCGTACATGCAGATCTGCGGTGGATCTCTCGTTAGCACCACCGTCGTCATATCAGCCGCTCACTGCTTCTGGAGCAACCTCAACCAGCAGCTACCCACAACTGACTATGCCGTTGCCGTCGGTAAGATTTACAGACCCTGGAACAATCCGAAGGACTTGGACGTCCAGAAATCGGATGTGAGGGATATAAAAATCCCGATAAGATTCCAAGGGAGGACGGCGAACTTTCAAGAGGACATAGCGATCGTGATACTGGCGACAAGGATCGAGTACCGCACCTACGTCAGGCCGGCCTGTCTGGACTTCGACATCAGCTTTGAGAGGCAGCAACTACAAGACGGGAAACCGGGCAAGGTGGCCGGTTGGGGTTTGACTTCGGAAAACGGCAACGCCTCGCAAATACTGAAAGTCGTTGATTTGCCATACATCGACATAGATAGGTGCATCGGCATGGCGCCTCCCGGGTTCAGGGAGTACATTAATGGCGACAAGATCTGCGCTGGCGACGGAGAAGGCAAAGCTTTATGCAAAGGGGACAGCGGCGGGGGCCTAGCTTTTTCCACTTACGACAAGGGAGTCGAAAGATACTATTTACGCGGAATCGTGTCAACGGCTTCGACGAACGAGAATCTGTGCAACACAAACACATTCACAACATTCACACAAGTCTCGAAACACGAACATTTCATCAAGCAATATCTGCACGTGGTTCAGACTTAG

Protein

MSRCQSNWFRCTYGACVDGTAPCNGIQECADNSDELLPQCRGNEVADATNLRDKFKCADGNVIPATAFCDGVADCPDGSDETVQACAGRTCPAYLFQCAYGACVDAGSDCNGIKECADGSDESDELCDRVLSGKPTQKPSASGGCVLPQYPAHGSYVVLNTPNATPGQTFDSIQVNVTCKPGYGVMGRNDVFCLNGWWSDKLPQCVRFCTLNSHASVEYKCLLTNGNEGTRPCGSLEPTGTIVQPQCRSPNYYSTVPLGYMRCIEGNWDYVATCTPECGRVTPDGEELVFGGRSAKRGELPWHAGIYRKTSTPYMQICGGSLVSTTVVISAAHCFWSNLNQQLPTTDYAVAVGKIYRPWNNPKDLDVQKSDVRDIKIPIRFQGRTANFQEDIAIVILATRIEYRTYVRPACLDFDISFERQQLQDGKPGKVAGWGLTSENGNASQILKVVDLPYIDIDRCIGMAPPGFREYINGDKICAGDGEGKALCKGDSGGGLAFSTYDKGVERYYLRGIVSTASTNENLCNTNTFTTFTQVSKHEHFIKQYLHVVQT

Similarity

Belongs to the peptidase S1 family.
Belongs to the mitochondrial carrier (TC 2.A.29) family.

Uniprot

I3WAD0   A0A2H1VKP2   Q69BL0   A0A2W1BIK5   A0A2A4J653   A0A2A4J8A8   + More
A0A2A4JXS9   Q5MGG8   A0A194Q760   A0A0N1PIR0   A0A2W1BGN3   A0A0N1PGE4   A0A194Q0Y4   A0A0N1I6Q2   A0A3S2LXN3   A0A2H1VLP9   A0A0N1PIX0   A0A2P8YP29   A0A0L7LGL1   A0A2J7RCH1   A0A067RJX7   A0A182LSY4   A0A182Q107   A0A0N1I8Z7   A0A182VRJ4   U5EPN9   A0A1Q3FMR3   A0A182GDV9   Q17H79   B0X3L4   A0A2M4AGF6   A0A2M4AFU1   A0A182NFK7   W5JJ60   A0A182X2R5   A0A182H7R9   A0A182HGT4   A0A182F8Q3   A0A182ITD4   A0A1S4GDQ4   Q7PY92   A0A2M4BGF8   A0A182KMB4   A0A2M4BGG7   A0A182RNY9   A0A0A9YJE5   A0A146LVV0   A0A224X923   A0A182TRW0   A0A182VJ48   T1H816   A0A2K8JMG0   D6WBK5   A0A1W4XIN2   A0A1W4XTP2   B1B5K3   A0A182XV86   A0A1Y1LR53   D6WAZ7   A0A170ZNF0   A0A1Y1LR62   A0A182P9S2   A0A084VWP2   A0A2A4J979   A0A1V1FIV2   J9JRX5   A0A154PEE3   A0A1L8DQQ0   A0A1J1J0Z5   A0A310SF19   N6USS0   U4UFJ4   A0A2A3ER96   A0A1B6E5L3   A0A088AKU8   J9K1E4   A0A0L7RG32   A0A1A9ZTA3   A0A1A9V5K8   A0A146LPF0   A0A1B0FPU9  

Pubmed

15190055    28756777    16023793    26354079    29403074    26227816    + More
24845553    26483478    17510324    20920257    23761445    12364791    20966253    25401762    26823975    18362917    19820115    18195005    25244985    28004739    24438588    28410430    23537049   

EMBL

JQ954757    AFK93534.1    ODYU01002842    SOQ40824.1    AY380790    AAR29602.1    + More
KZ150174    PZC72580.1    NWSH01003130    PCG66903.1    NWSH01002430    PCG68315.1    NWSH01000454    PCG76303.1    AY829818    AAV91432.2    KQ459580    KPI99230.1    KQ460246    KPJ16373.1    KZ150237    PZC71960.1    KQ460735    KPJ12635.1    KPI99211.1    KPJ12638.1    RSAL01000132    RVE46370.1    ODYU01003240    SOQ41738.1    KPJ12637.1    PYGN01000456    PSN46002.1    JTDY01001173    KOB74658.1    NEVH01005885    PNF38537.1    KK852636    KDR19731.1    AXCM01003686    AXCN02000208    KPJ16374.1    GANO01004615    JAB55256.1    GFDL01006237    JAV28808.1    JXUM01056539    JXUM01056540    KQ561915    KXJ77171.1    CH477252    EAT46012.1    DS232317    EDS39906.1    GGFK01006544    MBW39865.1    GGFK01006333    MBW39654.1    ADMH02001351    ETN62915.1    JXUM01028537    KQ560824    KXJ80737.1    APCN01005945    AAAB01008987    EAA01121.5    GGFJ01003008    MBW52149.1    GGFJ01003009    MBW52150.1    GBHO01011848    GBHO01011846    GBRD01011126    JAG31756.1    JAG31758.1    JAG54698.1    GDHC01007812    JAQ10817.1    GFTR01007569    JAW08857.1    ACPB03011663    KY031267    ATU83018.1    KQ971311    EEZ99332.2    AB363982    BAG14264.1    GEZM01049076    JAV76122.1    EEZ98916.1    GEMB01002039    JAS01140.1    GEZM01049075    JAV76123.1    ATLV01017677    ATLV01017678    ATLV01017679    KE525181    KFB42386.1    PCG68316.1    FX985348    BAX07361.1    ABLF02017553    KQ434887    KZC10211.1    GFDF01005380    JAV08704.1    CVRI01000063    CRL04521.1    KQ765323    KQ759877    OAD53988.1    OAD62273.1    APGK01017806    APGK01017807    APGK01017808    KB740053    ENN81797.1    KB632093    ERL88690.1    KZ288195    PBC33792.1    GEDC01004111    JAS33187.1    ABLF02038724    ABLF02038736    KQ414599    KOC69793.1    GDHC01009430    JAQ09199.1    CCAG010010748    CCAG010010749    CCAG010010750    CCAG010010751   

Proteomes

UP000218220    UP000053268    UP000053240    UP000283053    UP000245037    UP000037510    + More
UP000235965    UP000027135    UP000075883    UP000075886    UP000075920    UP000069940    UP000249989    UP000008820    UP000002320    UP000075884    UP000000673    UP000076407    UP000075840    UP000069272    UP000075880    UP000007062    UP000075882    UP000075900    UP000075902    UP000075903    UP000015103    UP000007266    UP000192223    UP000076408    UP000075885    UP000030765    UP000007819    UP000076502    UP000183832    UP000019118    UP000030742    UP000242457    UP000005203    UP000053825    UP000092445    UP000078200    UP000092444   

PRIDE

I3WAD0   

Pfam

PF00084   Sushi        + More
PF00057   Ldl_recept_a
PF00089   Trypsin
PF00153   Mito_carr
PF00004   AAA
PF01416   PseudoU_synth_1
PF00439   Bromodomain

Interpro

IPR023415   LDLR_class-A_CS        + More
IPR000436   Sushi_SCR_CCP_dom       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       
IPR009003   Peptidase_S1_PA       
IPR002172   LDrepeatLR_classA_rpt       
IPR036055   LDL_receptor-like_sf       
IPR035976   Sushi/SCR/CCP_sf       
IPR001314   Peptidase_S1A       
IPR018108   Mitochondrial_sb/sol_carrier       
IPR023395   Mt_carrier_dom_sf       
IPR013032   EGF-like_CS       
IPR000742   EGF-like_dom       
IPR001879   GPCR_2_extracellular_dom       
IPR003593   AAA+_ATPase       
IPR001487   Bromodomain       
IPR020095   PsdUridine_synth_TruA_C       
IPR003959   ATPase_AAA_core       
IPR020103   PsdUridine_synth_cat_dom_sf       
IPR036427   Bromodomain-like_sf       
IPR001406   PsdUridine_synth_TruA       
IPR020097   PsdUridine_synth_TruA_a/b_dom       
IPR041708   PUS1/PUS2-like       
IPR027417   P-loop_NTPase       
IPR003960   ATPase_AAA_CS       
IPR033116   TRYPSIN_SER       

SUPFAM

SSF50494   SSF50494        + More
SSF57535   SSF57535       
SSF57424   SSF57424       
SSF103506   SSF103506       
SSF55120   SSF55120       
SSF47370   SSF47370       
SSF52540   SSF52540       

Gene 3D

4.10.400.10     1.50.40.10     1.20.920.10     3.30.70.660    

CDD

cd00112  LDLa
cd00190  Tryp_SPc
cd00033  CCP
cd02568  PseudoU_synth_PUS1_PUS2

ProteinModelPortal

I3WAD0   A0A2H1VKP2   Q69BL0   A0A2W1BIK5   A0A2A4J653   A0A2A4J8A8   + More
A0A2A4JXS9   Q5MGG8   A0A194Q760   A0A0N1PIR0   A0A2W1BGN3   A0A0N1PGE4   A0A194Q0Y4   A0A0N1I6Q2   A0A3S2LXN3   A0A2H1VLP9   A0A0N1PIX0   A0A2P8YP29   A0A0L7LGL1   A0A2J7RCH1   A0A067RJX7   A0A182LSY4   A0A182Q107   A0A0N1I8Z7   A0A182VRJ4   U5EPN9   A0A1Q3FMR3   A0A182GDV9   Q17H79   B0X3L4   A0A2M4AGF6   A0A2M4AFU1   A0A182NFK7   W5JJ60   A0A182X2R5   A0A182H7R9   A0A182HGT4   A0A182F8Q3   A0A182ITD4   A0A1S4GDQ4   Q7PY92   A0A2M4BGF8   A0A182KMB4   A0A2M4BGG7   A0A182RNY9   A0A0A9YJE5   A0A146LVV0   A0A224X923   A0A182TRW0   A0A182VJ48   T1H816   A0A2K8JMG0   D6WBK5   A0A1W4XIN2   A0A1W4XTP2   B1B5K3   A0A182XV86   A0A1Y1LR53   D6WAZ7   A0A170ZNF0   A0A1Y1LR62   A0A182P9S2   A0A084VWP2   A0A2A4J979   A0A1V1FIV2   J9JRX5   A0A154PEE3   A0A1L8DQQ0   A0A1J1J0Z5   A0A310SF19   N6USS0   U4UFJ4   A0A2A3ER96   A0A1B6E5L3   A0A088AKU8   J9K1E4   A0A0L7RG32   A0A1A9ZTA3   A0A1A9V5K8   A0A146LPF0   A0A1B0FPU9  

PDB

4IGD     E-value=2.25354e-22,     Score=262

KEGG

101746626    K20674 modular serine protease [EC:3.4.21.-] | (RefSeq) HP14; uncharacterized LOC101746626

PATHWAY

04624    Toll and Imd signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0004252   GO:0016021   GO:0022857   GO:0016020   GO:0004930   GO:0005524   GO:0003723   GO:0009982   GO:0001522   GO:0006508   GO:0005515   GO:0008270   GO:0016701   GO:0006355   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

Length:

551

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.4177

Exp number, first 60 AAs:

0.0002

Total prob of N-in:

0.01991

outside

1  -  551

 

 

Pi

248.187166

Theta

154.522514

Tajima's D

1.804845

CLR

0

CSRT

0.846857657117144

Interpretation

Uncertain