Gene

KWMTBOMO14773  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003806

Annotation

PREDICTED:_dynactin_subunit_1_[Bombyx_mori]

Location

Bomo_Chr24(-):14843304-14890966      View in EpiBrowser

Full name

Dynactin subunit 1      

Alternative Name

150 kDa dynein-associated polypeptide
Dynactin 1 subunit p150
Protein glued

Location in the cell

Cytoplasmic   Reliability : 2.158

CDS

ATGTCCGATAAGGATTTAACTTTGGGGCAGCGGGTGATGGTCGTCGTTAAAGACGTGAAAGGCACAGTTGCTTATGTTGGATACCCAACATTCGCCACGGGGAAATGGATCGGCGTGATCTTGGATGAACCGAAGGGAAAAAACAACGGTACAGTCCGTGGTCACGCTTATTTCACTTGCGATGAGAATTTCGGTGTCTTCGTCCGTCCTGCCCAAATACAGCTGCTGGACGCCGATGACAATCCGATGGAGACATCCGTCACTACCCCCTCCGGGGACACCAAGACCGCTCTTGGTAGGAGATTGAGCAGTTCTCGCACCTCGCTGGCGAGCAGTCGGCAATCGTTGACGTCATACGCTTCGCCAACAACCGAAAGGGCATCTTCGCCTGAGGCGAAAAGAGCGTCTTTTGTCGAGACTGGTTTCGTCGAGACCCTCACTCCGCAGTACACACCAGGTCAGAGCATAACGTCCCCACAGCCCGTTCCTTCGTCCGTTGAAGATAAGCTGGCCAACCTTCAGGCCCAGCAAGAGATAACCCAACTGAAATCCGAAGTCGAAGACCTGAAAGAGAAACTGGAGACCGTCAAGGTTCGACGCGCCGAAGATCGGGAGAAGCTGCGCGAGCTGGAGCGTCTGAGGCTGCAGCTGGAGCAGGCGAACGAGTTCAAGACCAAGATCATGGAGTCTCAAGCTCAGCTGCAGAGGGATCTCCAGCGAGCGAAACAGGAGGTTCGCGAGGCCCAAGAAGCTCTAGAGGTCCACAACGACGAAACCGCCGAACTGTCGGAGGCGGCAGAGATGGCGGCCCTCGACAAGGAGATGGCGGAGGAGCGAGCCGAGGCCCTGCAGATGGAGTTGGAGCAGTGCCGGGAGAAGCTGGAAGAGGCCACTCTCGACCTGCAGCTGATGAAGGCCGAGATGGAAGCCGGCGGGAACATTCAGCACCCGTACGCAGCCGCCGACAGCGGAGCCACGGGCTACGAGATGAGGCAGCTACAGCAACAGAACATCCGCCTCAGGGATACCCTGGTCAGGCTGAGGGATCTAACCGCGCACGATAAGCACGAAATGCAGAAGATGCAGAAGGATCTAGAGCATTACAAGTCTGAGATCGCGGAACTGAGTCGAACCAAGGAGAAGCTGTCCGCTCGCGTCGAGGAACTGGAGGCGCAGGTCAGCGACCTCCGCGAGCAGGTGGACGCGGCTCTGGGAGCCGAAGAGATGGTCGAGCAATTGGCCGAGAAGAAGATGGCCTTGGAAGATCAGGTGGAACAGCTGAGGCAGGACGTATCGGAGCTGGAGGCCCTTCAGGAAGTCCACGAGCAACTGGTCGAGTCGAACCGTGAGCTCGAGATGGATCTGCGTGAGGAGTTGGAGATGGCTCACGCGGCCACCAGGGAGGCGATGAGAGAGAGAGAGGCAGTGTTCGAGACGATACTCGACCGCGACTCCACGATCCTCAAGTTCAGAGAGCTGGTGCAGAGAATGACCGAGCAGTACAACGAGTTGCGGAATCAGCTGGAAAACAAACAGGAGTCGGAATCGCTCCGCCCCCGGCCGGAGAGCGAGAGCAACGGGGAGGGAGGGGAGGCTCCCCCTCGTTCCCCCCCGGCCGAGCTCACGTCCCTGATGGCGGCGTCGCGCGCCTGCACCCGCAGCGTGGACCTGCGCCTGCGGGCCCTCGACCTGGCGCAGGCGGGCGCCCGGGCCGACATGCTGGCTGCCTGCCTCCCGGACCACTTCATGCAGCCCTCAGGCGACCACGACGCCATCCTTCTGATACTGCTGCTGCAGAGGCTGCACACGAAGGCGGAGATCATATTAGGACCGATCAGAGAGAGATTCCCGGCGGTGAACGTGTGGGATCGCGAGGTGGTCACGAAGACTCACACCGCGGTCCAGTACAGCTTCAGGTGTCAGCTCGAATACCAGTTGCACATGATACAGGGTATCGTGAGCATGTGGATAACGGCTCTGGAGACGTGCTCCCCGGAGGTCCTGCTGCGCTGCGCCAGCGCCCTACCCGACGCCCTCCAGCAGGAGAAGATGCTCGACGCCTACATCCACTTCCTGAAGTACAACGAGCTGGACGAGAACTGCGCTCTGGACGGGCTGGAGCGTGCGTGGAGCTACCTGTCGGCGATGTGGGGCGCGCTGGGGCTGCGCGACGGGCCGGCGCGGGAGCCGCTGCTGCACACCGTGGCCGCGCTGGACGCCCTGGCGCGCGCGCTCGCCGCCGACGCCTCCGCCCTCAAGCACATACTGAAGGAGTCCGACAGGGAGTTGGAGCTGGGGTCGCTGCACGCGGACATCTACGCGAGCGCCAACGCGCTGCAACAGCAGCTCAAGGGCATCAAGCGGCGCCTGCCGCCCGGGGCCAGTCTGCAGGCCGTCAACATCGACCCGAAGCTGGTGGAGAGCCTCCGCGAGGAATGCGGGCCGGTGCTGTGGCGCTGCAGCCGCGCGTGCTCGCTGGCGGCGCGGGCGGCGGCCACCGCGGCCGAGAGCGCGGGGGCGCAGGCCGAGGGCGCGCCGCTGCCCCACCAGGCCCTCGCCGCCATATGGACCAAGGCTGTCTACAAGCTCTACCAGCAGGATGACCACAGCGTGGTGAAGATCATCAAGCAATCCTTGGCGCAGGTCACGGTGGACGTCAACAAACTTGCCGCGTTCGCTCAAGACAAGGAATACGATATGATGTCCTTAACCAACGTTGCCACTGAGAAGCCAACACCGCCGGTGGTCATCAGAGCGCAGCTGGTGAAGAAACAGCTCGAGGAAACTAAGATCCTGACGATAAAACTGGAGAACAAAGAAGCCGATATTAAAGAGCTCCGGAAAGCTCTGAAGGCCAAGCAAGAAGAAGTCTCCGAGATGCAGATCCGGAAAGAGCTGGGCGAGAGGAAGCTGACGACGGCGGCCAGGGACGCGGAGCTGCGCTCTCAGCAGCTGCAGAGGAAGCTGGAGGACGCTCAGAATCAATTGAGAAGGAAAGAGAAAGAGTACGAGGAGACCATGGATCATCTTCAGCACGATATAGATTCGCTGGAGAACGAACGTGGCGCTCTGAGGGATAAGCTGAAGCTTTACGCCAAGAGGGGCGGCGGACATCACGAGGAGGCACCCTTGAAGGTCGCCCCAGGAGTAGCCGCCGGCGAAGTCAACGAAGCCCTACAGCATCAGCTTAAGGTCCTCAGCTGGACTGTGGAGAGGGAGAGGGCCGCTCGCATAACCGCGTGCCGCAAGGCTGAGATACAGACCCTGAGGAGGCTGAGACCTCTAGAGCATCCGACGGCACCGGGAGCCGTGGCCAGGAGACAGGTCGCCAGCCAACTCGAGAAGGAGCTAAACGAATTGCAAACTAAGTGGACGTTGTTCGTTGCCCGGTCCGGTCTGGTTCAGTTCCCGTCGGAGCCGGGGAAGTACGCCCGCGCCCTTCAGATACACCGAGAGAAGCAGCGGGAGACGAAACAGCGTCTGGAGGAGCGCCTGTCGGCCCTGCAGGCGGAGGCGCGTCGCCAGCTGTTGCTGCACCGGCCTTGGAGGTGCGTGGAGGCGGACCTCGCGGAGTTCCCGGCGCCGGACCTCGCCGCGGCGATCGCGCCCAAGACGGTGGACATCGGAACGATAAAGTTCCCTGCATCGGACCAGGGGCCCAACGACGACACGATATACGTCACGCCGAGCCAGCTGTCCGCATTGCGAGATCTGGTGGCTGAATTGCAGTCAGACGACATCAAACTCGAACTCACGACCCTCGAGCCGACGGTCTGCGCGGCCTGA

Protein

MSDKDLTLGQRVMVVVKDVKGTVAYVGYPTFATGKWIGVILDEPKGKNNGTVRGHAYFTCDENFGVFVRPAQIQLLDADDNPMETSVTTPSGDTKTALGRRLSSSRTSLASSRQSLTSYASPTTERASSPEAKRASFVETGFVETLTPQYTPGQSITSPQPVPSSVEDKLANLQAQQEITQLKSEVEDLKEKLETVKVRRAEDREKLRELERLRLQLEQANEFKTKIMESQAQLQRDLQRAKQEVREAQEALEVHNDETAELSEAAEMAALDKEMAEERAEALQMELEQCREKLEEATLDLQLMKAEMEAGGNIQHPYAAADSGATGYEMRQLQQQNIRLRDTLVRLRDLTAHDKHEMQKMQKDLEHYKSEIAELSRTKEKLSARVEELEAQVSDLREQVDAALGAEEMVEQLAEKKMALEDQVEQLRQDVSELEALQEVHEQLVESNRELEMDLREELEMAHAATREAMREREAVFETILDRDSTILKFRELVQRMTEQYNELRNQLENKQESESLRPRPESESNGEGGEAPPRSPPAELTSLMAASRACTRSVDLRLRALDLAQAGARADMLAACLPDHFMQPSGDHDAILLILLLQRLHTKAEIILGPIRERFPAVNVWDREVVTKTHTAVQYSFRCQLEYQLHMIQGIVSMWITALETCSPEVLLRCASALPDALQQEKMLDAYIHFLKYNELDENCALDGLERAWSYLSAMWGALGLRDGPAREPLLHTVAALDALARALAADASALKHILKESDRELELGSLHADIYASANALQQQLKGIKRRLPPGASLQAVNIDPKLVESLREECGPVLWRCSRACSLAARAAATAAESAGAQAEGAPLPHQALAAIWTKAVYKLYQQDDHSVVKIIKQSLAQVTVDVNKLAAFAQDKEYDMMSLTNVATEKPTPPVVIRAQLVKKQLEETKILTIKLENKEADIKELRKALKAKQEEVSEMQIRKELGERKLTTAARDAELRSQQLQRKLEDAQNQLRRKEKEYEETMDHLQHDIDSLENERGALRDKLKLYAKRGGGHHEEAPLKVAPGVAAGEVNEALQHQLKVLSWTVERERAARITACRKAEIQTLRRLRPLEHPTAPGAVARRQVASQLEKELNELQTKWTLFVARSGLVQFPSEPGKYARALQIHREKQRETKQRLEERLSALQAEARRQLLLHRPWRCVEADLAEFPAPDLAAAIAPKTVDIGTIKFPASDQGPNDDTIYVTPSQLSALRDLVAELQSDDIKLELTTLEPTVCAA

Subunit

Large macromolecular complex of at least 10 components; p150(glued) binds directly to microtubules and to cytoplasmic dynein.

Similarity

Belongs to the dynactin 150 kDa subunit family.

Keywords

Coiled coil   Complete proteome   Cytoplasm   Cytoskeleton   Dynein   Microtubule   Phosphoprotein   Reference proteome  

Feature

chain  Dynactin subunit 1

Uniprot

H9J2R9   A0A3S2PEG7   A0A212FBK1   A0A212F4A8   U5EZ92   A0A182H514   + More
A0A1L8DXM2   A0A1B0CNT5   Q177H6   A0A1Q3FFS5   A0A1J1IPL7   A0A182YGR0   A0A182FSB7   A0A2M4A815   A0A2M4A7S9   D6X2E3   A0A182Q6N6   A0A182MM21   A0A139WCF6   A0A182NLF0   W5JBT6   A0A182W1F0   A0A182JQ22   A0A182PKP5   A0A1Y1MAF5   A0A182VP39   A0A182I7P5   A0A182TYL0   A0A182S043   A0A182XJ65   Q7PQM8   A0A182L787   A0A084VNR8   A0A182J6P7   B4KUU8   B0W933   B4IZ99   B4LCT4   Q2M015   B4H8Z3   A0A336KRA6   B3NHI4   A0A1B0D603   B3MAH5   B4PHX3   A0A232FA62   K7IP76   A0A2M4D0E0   A0A0J9RW74   B4HH93   P13496   A0A2M4A8Z6   A0A026WF66   A0A1W4UKA8   A0A0C9RRZ8   A0A0P4W7T9   E2BH22   A0A3B0J963   A0A195FGL6   A0A195BEZ2   A0A3R7NEH5   A0A336KTV7   A0A034VYZ2   A0A034VYZ9   A0A0K8WAU9   E9ICA4   W8AV63   A0A1A9WCS3   A0A0A1WVQ8   A0A154PGT7   A0A1B0FA12   A0A1A9Y9U7   A0A1A9VMQ0   A0A1A9ZMW2   B4N4P0   A0A1B0BKA7   A0A1B0C5N2   A0A151WR13   A0A1I8PDX1   A0A1I8N2U4   E0VB37   A0A0P4WBW4   A0A336MY70   A0A0C9RUQ3   A0A3L8E0F6   A0A195E3U0   A0A088AEZ5   A0A158NWG6   A0A2A3ECG3   A0A0C9RE07   B4QJH8   V9IAX6   E9G080   A0A0M8ZS69   N6U2P0  

Pubmed

19121390    22118469    26483478    17510324    25244985    18362917    + More
19820115    20920257    23761445    28004739    12364791    14747013    17210077    20966253    24438588    17994087    18057021    15632085    17550304    28648823    20075255    22936249    2819881    10731132    12537572    12537569    18327897    24508170    20798317    25348373    21282665    24495485    25830018    25315136    20566863    30249741    21347285    21292972    23537049   

EMBL

BABH01036983    BABH01036984    BABH01036985    BABH01036986    BABH01036987    BABH01036988    + More
RSAL01000072    RVE49060.1    AGBW02009314    OWR51097.1    AGBW02010407    OWR48570.1    GANO01001210    JAB58661.1    JXUM01110566    JXUM01110567    KQ565425    KXJ70991.1    GFDF01003079    JAV11005.1    AJWK01020834    CH477376    EAT42301.1    GFDL01008647    JAV26398.1    CVRI01000057    CRL02189.1    GGFK01003598    MBW36919.1    GGFK01003526    MBW36847.1    KQ971371    EFA10255.2    AXCN02000131    AXCM01001304    KYB25597.1    ADMH02001952    ETN60335.1    GEZM01036318    GEZM01036317    JAV82812.1    APCN01002523    AAAB01008880    EAA08600.6    EGK97012.1    ATLV01014856    KE524991    KFB39612.1    CH933809    EDW19354.1    DS231862    EDS39730.1    CH916366    EDV96654.1    CH940647    EDW70976.1    KRF85224.1    CH379069    EAL31122.1    CH479226    EDW35208.1    UFQS01000753    UFQT01000753    SSX06638.1    SSX26985.1    CH954178    EDV51710.1    AJVK01025583    AJVK01025584    CH902618    EDV40226.1    KPU78454.1    CM000159    EDW94448.1    NNAY01000591    OXU27512.1    GGFL01006390    MBW70568.1    CM002912    KMY99484.1    CH480815    EDW41418.1    J02932    AE014296    AY118377    BT044559    GGFK01003879    MBW37200.1    KK107250    EZA54326.1    GBYB01011355    JAG81122.1    GDRN01075478    JAI63050.1    GL448268    EFN84943.1    OUUW01000002    SPP76462.1    KQ981606    KYN39521.1    KQ976509    KYM82735.1    QCYY01000449    ROT85060.1    UFQS01000940    UFQT01000940    SSX07871.1    SSX28105.1    GAKP01012209    JAC46743.1    GAKP01012199    JAC46753.1    GDHF01027660    GDHF01004334    JAI24654.1    JAI47980.1    GL762231    EFZ21775.1    GAMC01018022    JAB88533.1    GBXI01011789    JAD02503.1    KQ434902    KZC11075.1    CCAG010018115    CH964095    EDW79114.1    KRF99012.1    JXJN01015851    JXJN01026095    KQ982815    KYQ50248.1    DS235021    EEB10593.1    GDRN01075479    JAI63049.1    UFQT01003593    SSX35130.1    GBYB01011356    JAG81123.1    QOIP01000002    RLU25528.1    KQ979685    KYN19813.1    ADTU01000450    KZ288287    PBC29427.1    GBYB01011357    JAG81124.1    CM000363    EDX10387.1    JR037135    AEY57601.1    GL732528    EFX87445.1    KQ435879    KOX69877.1    APGK01041744    KB740997    ENN75835.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000069940    UP000249989    UP000092461    + More
UP000008820    UP000183832    UP000076408    UP000069272    UP000007266    UP000075886    UP000075883    UP000075884    UP000000673    UP000075920    UP000075881    UP000075885    UP000075903    UP000075840    UP000075902    UP000075900    UP000076407    UP000007062    UP000075882    UP000030765    UP000075880    UP000009192    UP000002320    UP000001070    UP000008792    UP000001819    UP000008744    UP000008711    UP000092462    UP000007801    UP000002282    UP000215335    UP000002358    UP000001292    UP000000803    UP000053097    UP000192221    UP000008237    UP000268350    UP000078541    UP000078540    UP000283509    UP000091820    UP000076502    UP000092444    UP000092443    UP000078200    UP000092445    UP000007798    UP000092460    UP000075809    UP000095300    UP000095301    UP000009046    UP000279307    UP000078492    UP000005203    UP000005205    UP000242457    UP000000304    UP000000305    UP000053105    UP000019118   

PRIDE

H9J2R9    P13496   

Pfam

PF01302   CAP_GLY        + More
PF12455   Dynactin
PF03178   CPSF_A

Interpro

IPR036859   CAP-Gly_dom_sf        + More
IPR022157   Dynactin       
IPR000938   CAP-Gly_domain       
IPR027663   DCTN1       
IPR004871   Cleavage/polyA-sp_fac_asu_C       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR036322   WD40_repeat_dom_sf       

SUPFAM

SSF74924   SSF74924        + More
SSF50978   SSF50978       

Gene 3D

2.30.30.190     2.130.10.10    

ProteinModelPortal

H9J2R9   A0A3S2PEG7   A0A212FBK1   A0A212F4A8   U5EZ92   A0A182H514   + More
A0A1L8DXM2   A0A1B0CNT5   Q177H6   A0A1Q3FFS5   A0A1J1IPL7   A0A182YGR0   A0A182FSB7   A0A2M4A815   A0A2M4A7S9   D6X2E3   A0A182Q6N6   A0A182MM21   A0A139WCF6   A0A182NLF0   W5JBT6   A0A182W1F0   A0A182JQ22   A0A182PKP5   A0A1Y1MAF5   A0A182VP39   A0A182I7P5   A0A182TYL0   A0A182S043   A0A182XJ65   Q7PQM8   A0A182L787   A0A084VNR8   A0A182J6P7   B4KUU8   B0W933   B4IZ99   B4LCT4   Q2M015   B4H8Z3   A0A336KRA6   B3NHI4   A0A1B0D603   B3MAH5   B4PHX3   A0A232FA62   K7IP76   A0A2M4D0E0   A0A0J9RW74   B4HH93   P13496   A0A2M4A8Z6   A0A026WF66   A0A1W4UKA8   A0A0C9RRZ8   A0A0P4W7T9   E2BH22   A0A3B0J963   A0A195FGL6   A0A195BEZ2   A0A3R7NEH5   A0A336KTV7   A0A034VYZ2   A0A034VYZ9   A0A0K8WAU9   E9ICA4   W8AV63   A0A1A9WCS3   A0A0A1WVQ8   A0A154PGT7   A0A1B0FA12   A0A1A9Y9U7   A0A1A9VMQ0   A0A1A9ZMW2   B4N4P0   A0A1B0BKA7   A0A1B0C5N2   A0A151WR13   A0A1I8PDX1   A0A1I8N2U4   E0VB37   A0A0P4WBW4   A0A336MY70   A0A0C9RUQ3   A0A3L8E0F6   A0A195E3U0   A0A088AEZ5   A0A158NWG6   A0A2A3ECG3   A0A0C9RE07   B4QJH8   V9IAX6   E9G080   A0A0M8ZS69   N6U2P0  

PDB

2HL5     E-value=2.08639e-15,     Score=206

KEGG

101737198    K04648 dynactin 1 | (RefSeq) dynactin subunit 1

GO

GO:0070840   GO:0005869   GO:0010970   GO:0016021   GO:0005634   GO:0003676   GO:0061670   GO:0000776   GO:0007349   GO:0042052   GO:0008017   GO:0005828   GO:0001709   GO:0050772   GO:1990049   GO:0016330   GO:0045505   GO:0005818   GO:1904115   GO:0006886   GO:0035011   GO:0051642   GO:0048491   GO:0051256   GO:0061176   GO:0019896   GO:0030496   GO:0051028   GO:0034501   GO:0051383   GO:0035149   GO:0048675   GO:0051299   GO:0031616   GO:0045198   GO:0005737   GO:0030286   GO:0007018   GO:0001751   GO:0008090   GO:0005876   GO:0003774   GO:0001754   GO:0000278   GO:0051225   GO:0048489   GO:0005813   GO:0042051  

PANTHER

PTHR18916:SF75  

Subcellular location

Cytoplasm  
Cytoskeleton  

Length:

1261

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.45909

Exp number, first 60 AAs:

2.45896

Total prob of N-in:

0.12183

outside

1  -  1261

 

 

Pi

260.083288

Theta

165.922729

Tajima's D

2.093636

CLR

0.148764

CSRT

0.897255137243138

Interpretation

Uncertain