Gene

KWMTBOMO14758

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr24(+):14494647-14498614      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Nuclear   Reliability : 3.041

CDS

ATGGAGCAGGTAATGACCGCACTTCTTTCTATTCAAAAAGAACTCGACGAACAGAAAAAACTTATACACAAAAAAGGGGAAGAAGTGACAGAGAAGGTAACATTAAATATAAATAAGATACTAGAAGAGAAATTAAAAAATTTGGAAGAAAAACATGAAAACCTTAAGTCGAGGGTGGAAAATCAAGAGCAAAGATTATACTACATGGAGAGACAATCAAGACAACGTAATCTAGTCTTCTTTGGATTGGAGGAACACGAAAAATCCTACTCAAATTTAGAAAACACTATAGTAGACTTTGTACATAAATACTTCCCAATACAAATAGACCATAAAGACTTACAAGCGATCAGAAGAATAGGGAAGAGGACTAAAAAGCCACGACCGATAGTTATTACTTTCACAACACTTGGTAAGAAGATAGATATCTTAAAGGGCAAAGGAGCTTTAAAAGAAACACCGTATTATATCAAAGAAGACTACCCTCAATCAGTCTTGCAAAAAAGAAAAGAGCTACAGGAGCAAGTTATAGCAGAAAGAGAGAAGGGTAATAAAGCCATTATTAAATACGACAAGCTTGTTCTACTAAATAACTCATCCAAAGACCCGAAAAACAATAAAAGAAATCTATCAGAATCTCCAGAGAATAACACAATCAACCATGCCGGGCAGATATCTCAAGCAAACAAAAAGAACAAAACCTTGGCTGCCCACATAATCCAAAGGTCTCTGTCATCAATACACCGATACTTAGAACTCAATAATGCATTGAAAGATATAAAATGCGACATACTAGGACTCTCAGAAACAAGAAAAATGGGCTGCCACATAGAAGAGTATTCAGACTATGTTTTCTGCTATATAGGAGAAACAAAGGGATTGTATGGAGTCGGATTTTTAATAAAAAAGGCATGGAAAAACGATATAACTAACTTCACTGGCATTTCGGAGAGAGTAGCGCTACTTCAAATGAATTTTGGCGGACTAGACATTTCTATAATTCAGGCATACGCACCCACGGAAAAATCAGACGATACAGAAATACAAAAATTCTACAATGATCTGAAAAAAGCTCATACACTATCAAATGAGAAAATCATAATATTAGGAGACTTCAATGCAAAAATAGGGCAACCCAAAAAAGAAGAAAAACTCGTCATGGGACAGTACGGGCTAGGCCAAAGAAACGAAAGAGGCGAAAGACTGCTAGAATATGCATTGGAATATAGACTAGCAATAATCAACACTTATTTCAAAAAAAGACCCAGCAGAAGATGGACTTGGAAGTCACCAGACGAAAAAGTTAAAAACGAAATCGACTACATCATGACAAATGTCCCAAAAATAGTCCAAAATTATGAAGTTCTCAACAACGTAAAGTTCCAAACAGACCATAGACTACTTAGAGCAACAGTTCTATTGAGTCAAGCGAAAAAAAATAGAAAAGGCTTTAAACCACCACCAAAAATCCCAAAAAATGAAGAAGAAACAAGATACTACATAGACAGCCTCAAATCGAACATCGAAACCAAACTAGCAGATACCAGAAACGTTCAATCTTACTATGATGCGCTAGAAATAGCTATAACAAAAAGTTTAACTAGCAAAAACAATACAAAAAAAGAAAAACGACACAAAATATTTAGCGAAGAAACACTAGCCTTAATTAACAAACGCAGTGAATTAACTCTAAGAAAGAATAAAGATGCTGATACAAAGAAAGAACTAAGCAAATTATATAAGGAAACTAGCAAAGCGATTAAAAGAGACTATAGTAAGCACAGGCAAAGGATAATAACAGAAAAATTAAATAAATTCCGAAGCACAAAGAGAGCTTTTAAAGAATTAAACTTAAGAAAAACTTGGATACAAAAACTAGAAGGCCAACATAAAGAAATTACAACAAGACAAGAAATCGTACAGAAGGCAACTTCTTTCTACCAAGAATTATACAAAAACAAAAATAAAACCATCAAGGAAGCTAACGATTCACACAACTGTTATAACACGGAAACAATTAGACCGATAGAAGAAAAAGATACATACGCGCAGCTGAAGCATCTGAAATCAGATAAAAGTCCCGGTCCCGACGCAATAACCAATGAAGCTCTGAAAATAGGCGCACCAGTTTTACTTAAGCCTCTCACAGAATTATTCAATCTCATACTAGAAGCTGAAATCGTACCAATCCAATGGTGCACGTCGGACATCATATTACTATATAAAAAAGGAAACCCCCTCGATATCAACAACTATAGACCAATTAGCTTACTGGCAAATATATACAAAATCTTCTCATCTATAATTCTTAAACGCATAACACAAGAGATTGAAAAGGCACAACCAATAGAACAAGCTGGCTTTCGTTCTGGGTTTAGCACACTAGACCATATACAGGCACTAGAACAAGTTATAGAAAAATACGAAGAGTTTAATAAGCCACTCTATCTAGGTTTTATCGACTACAGCAAAGCCTTTGACAGCATAAGCCACAACTCTATATGGAAATCACTAAAGAAATTAAACATAAATTCGAAATATTTAAATATTATAAAATATATATACAACAACAGCATAAGTTATGTGAAGCTAGAATCTAGAGGTGATGCAATTAATATTGAAAGAGGAGTCAGACAGGGGGACCCCCTGTCACCTAAGCTGTTTATAGCGGTTCTAGAAGATGTATTTCGAAACACAGACTGGAAAAATAGAGGTATAAAAATAAACAACAGGTATCTAAGCCATCTCAGATTTGCGGACGACATAGTTATGCTGTCTGAAACAGCAAATGAATTACAAGATATGCTCCGCTCTCTTGTTCAAGCGAGCTCACAAGTAGGATTAGAGATGAATGCTACAAAAACCAAAATCATGACAAACAGCATAGAACGACCCATCAATGTAAAAGGAAAAACTATAGAATATGTCTACAGTTACATCTACCTAGGTATACAAATATCATTTTTAAAAACGCACAATGAAGACGAAATTGAAAGAAGAACAATCATAGCCTGGAAGAAATTTTGGTCACTCAGAGAAATTTTAAAAGGAGACTACTCAATAAACCTTAAGAAAACTGTATTAGACACCTGTATACTGCCTTGTCTACTGTATGGCTGCCAAACTTGGGTATACACGACAAGAGCAAAACAAAGAATTACAACAACACAAAGAGCTATGGAGAGAAGTATCCTAAACATAAGAAAAATTCAAAAAGTCAGGAGCAAAGTAATAAGACAGAAAACAAAGATAACAGATGCCCTCACACAAGCTCTAAAATTGAAATGGCAGTGGGCAGGTCACGTATTGAGATACACAGACACCAGGTGGACAGTCAACACTACAATCTGGAAAGGGCCAATTGGCAAAAGAAGGGTAGGGAGACCGAAAAGACGATGGGCTGACGACATAACCGAAATAATAGGAAAGGACTGGCAAACGATCGGCAAGGACAGAGATCAGTGGAAAGGACTGGAGGAGGCCTTCACCCGAGATGAGGGGTCCACATCCAATAACAAAAATTAA

Protein

MEQVMTALLSIQKELDEQKKLIHKKGEEVTEKVTLNINKILEEKLKNLEEKHENLKSRVENQEQRLYYMERQSRQRNLVFFGLEEHEKSYSNLENTIVDFVHKYFPIQIDHKDLQAIRRIGKRTKKPRPIVITFTTLGKKIDILKGKGALKETPYYIKEDYPQSVLQKRKELQEQVIAEREKGNKAIIKYDKLVLLNNSSKDPKNNKRNLSESPENNTINHAGQISQANKKNKTLAAHIIQRSLSSIHRYLELNNALKDIKCDILGLSETRKMGCHIEEYSDYVFCYIGETKGLYGVGFLIKKAWKNDITNFTGISERVALLQMNFGGLDISIIQAYAPTEKSDDTEIQKFYNDLKKAHTLSNEKIIILGDFNAKIGQPKKEEKLVMGQYGLGQRNERGERLLEYALEYRLAIINTYFKKRPSRRWTWKSPDEKVKNEIDYIMTNVPKIVQNYEVLNNVKFQTDHRLLRATVLLSQAKKNRKGFKPPPKIPKNEEETRYYIDSLKSNIETKLADTRNVQSYYDALEIAITKSLTSKNNTKKEKRHKIFSEETLALINKRSELTLRKNKDADTKKELSKLYKETSKAIKRDYSKHRQRIITEKLNKFRSTKRAFKELNLRKTWIQKLEGQHKEITTRQEIVQKATSFYQELYKNKNKTIKEANDSHNCYNTETIRPIEEKDTYAQLKHLKSDKSPGPDAITNEALKIGAPVLLKPLTELFNLILEAEIVPIQWCTSDIILLYKKGNPLDINNYRPISLLANIYKIFSSIILKRITQEIEKAQPIEQAGFRSGFSTLDHIQALEQVIEKYEEFNKPLYLGFIDYSKAFDSISHNSIWKSLKKLNINSKYLNIIKYIYNNSISYVKLESRGDAINIERGVRQGDPLSPKLFIAVLEDVFRNTDWKNRGIKINNRYLSHLRFADDIVMLSETANELQDMLRSLVQASSQVGLEMNATKTKIMTNSIERPINVKGKTIEYVYSYIYLGIQISFLKTHNEDEIERRTIIAWKKFWSLREILKGDYSINLKKTVLDTCILPCLLYGCQTWVYTTRAKQRITTTQRAMERSILNIRKIQKVRSKVIRQKTKITDALTQALKLKWQWAGHVLRYTDTRWTVNTTIWKGPIGKRRVGRPKRRWADDITEIIGKDWQTIGKDRDQWKGLEEAFTRDEGSTSNNKN

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Uniprot

A0A2H1WF27   D7F178   D7F177   A0A2H1VS24   D7F179   D7F176   + More
A0A2W1BZV1   A0A023EXV2   A0A069DZM5   D7F164   D7F157   D7F165   D7F159   D7F160   D7F166   D7F158   A0A016S1D2   A0A0K0FAW8   A0A016WPY4   A0A016WCB8   A0A016ULU9   A0A016SX67   G0MZ46   A0A016VEC1   A0A016VCD9   A0A0N5C0B1   A0A016SGC3   A0A016VBP7   A0A016TK11   A0A016T590   A0A016TNS4   A0A016TMT8   A0A016W4R1   A0A016SG46   A0A016TNH6   A0A016VCU3   A0A016TNL1   A0A2W5U8K4   A0A016W1X2   A0A016U784   A0A016S403   A0A016VCK8   A0A016V419   A0A2H2JFN0   A0A016WA79   A0A016VVN3   A0A016V6A2   A0A016S795   A0A016UY78   A0A016THC6   A0A016S5B2   A0A016UN79   A0A016RV73   A0A016RUR3   A0A016SLV8   A0A016T7J7   Q9TZX4   A0A016RRX8   K7IG35   K7IG36   A0A016WHK1   A0A016VV43   K7I2A2   A0A2H2J8I4   A0A016U4H4   K7ICT1   K7I2A3   K7ICT2   K7I2A1   K7H0R0   A0A023EWU8   K7H0Q9   A0A016VAS7   K7H0Q8   K7IBZ6   K7HDM2   K7HDM3   A0A0P4VWD0   K7IBZ5   A0A016WEQ1   A0A2H2JKG1   A0A2H2JKX8   A0A2H2JCS8  

EC Number

4.6.1.2

Pubmed

20470440    28756777    25474469    26334808    25730766    8603714    + More
9729877    27129103   

EMBL

ODYU01008249    SOQ51673.1    FJ265563    ADI61831.1    FJ265562    ADI61830.1    + More
ODYU01004088    SOQ43598.1    FJ265564    ADI61832.1    FJ265561    ADI61829.1    KZ149907    PZC78256.1    GBBI01004876    JAC13836.1    GBGD01000380    JAC88509.1    FJ265549    ADI61817.1    FJ265542    ADI61810.1    FJ265550    ADI61818.1    FJ265544    ADI61812.1    FJ265545    ADI61813.1    FJ265551    ADI61819.1    FJ265543    ADI61811.1    JARK01001655    EYB84321.1    JARK01000173    EYC41342.1    JARK01000388    EYC37469.1    JARK01001370    EYC16150.1    JARK01001500    JARK01001343    EYB95040.1    EYC28825.1    GL379822    EGT48339.1    JARK01001348    EYC25048.1    EYC25050.1    JARK01001568    EYB89432.1    EYC25049.1    JARK01001676    JARK01001446    JARK01001433    EYB83199.1    EYC01126.1    EYC02928.1    JARK01001473    EYB97806.1    JARK01001424    EYC04317.1    EYC04314.1    JARK01001337    EYC34625.1    JARK01001565    EYB89683.1    EYC04315.1    EYC25046.1    EYC04316.1    QFQQ01000179    PZR20596.1    JARK01001338    EYC33297.1    JARK01001389    EYC11015.1    JARK01001639    EYB85201.1    EYC25145.1    JARK01001354    EYC21986.1    JARK01000460    EYC36749.1    JARK01001340    EYC30828.1    JARK01001353    EYC22263.1    JARK01001621    EYB86109.1    JARK01001359    EYC20105.1    JARK01001438    EYC02111.1    JARK01001626    EYB85833.1    EYC16376.1    JARK01001700    JARK01001393    EYB82228.1    EYC10181.1    JARK01001711    EYB81734.1    JARK01001543    EYB91356.1    JARK01001736    JARK01001462    JARK01001379    EYB80775.1    EYB98943.1    EYC13646.1    EYC33347.1    AF054983    AAC72298.1    JARK01001730    EYB81048.1    JARK01000314    EYC38488.1    EYC31464.1    EYC10025.1    GBBI01004877    JAC13835.1    JARK01001349    EYC24520.1    GDKW01001596    JAI54999.1    JARK01000347    EYC38051.1   

Proteomes

UP000024635    UP000035680    UP000008068    UP000046392    UP000005237   

PRIDE

D7F178    D7F177    D7F179    D7F176    D7F164    D7F157    + More
D7F165    D7F159    D7F160    D7F166    D7F158   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07714   Pkinase_Tyr
PF00211   Guanylate_cyc
PF01094   ANF_receptor
PF03372   Exo_endo_phos
PF00069   Pkinase
PF00201   UDPGT

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR029052   Metallo-depent_PP-like       
IPR011009   Kinase-like_dom_sf       
IPR001170   ANPR/GUC       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR001828   ANF_lig-bd_rcpt       
IPR029787   Nucleotide_cyclase       
IPR000719   Prot_kinase_dom       
IPR001054   A/G_cyclase       
IPR028082   Peripla_BP_I       
IPR017441   Protein_kinase_ATP_BS       
IPR008271   Ser/Thr_kinase_AS       
IPR002213   UDP_glucos_trans       

SUPFAM

SSF56219   SSF56219        + More
SSF53822   SSF53822       
SSF55073   SSF55073       
SSF56112   SSF56112       

Gene 3D

3.60.10.10     3.60.21.10     3.30.70.1230    

ProteinModelPortal

A0A2H1WF27   D7F178   D7F177   A0A2H1VS24   D7F179   D7F176   + More
A0A2W1BZV1   A0A023EXV2   A0A069DZM5   D7F164   D7F157   D7F165   D7F159   D7F160   D7F166   D7F158   A0A016S1D2   A0A0K0FAW8   A0A016WPY4   A0A016WCB8   A0A016ULU9   A0A016SX67   G0MZ46   A0A016VEC1   A0A016VCD9   A0A0N5C0B1   A0A016SGC3   A0A016VBP7   A0A016TK11   A0A016T590   A0A016TNS4   A0A016TMT8   A0A016W4R1   A0A016SG46   A0A016TNH6   A0A016VCU3   A0A016TNL1   A0A2W5U8K4   A0A016W1X2   A0A016U784   A0A016S403   A0A016VCK8   A0A016V419   A0A2H2JFN0   A0A016WA79   A0A016VVN3   A0A016V6A2   A0A016S795   A0A016UY78   A0A016THC6   A0A016S5B2   A0A016UN79   A0A016RV73   A0A016RUR3   A0A016SLV8   A0A016T7J7   Q9TZX4   A0A016RRX8   K7IG35   K7IG36   A0A016WHK1   A0A016VV43   K7I2A2   A0A2H2J8I4   A0A016U4H4   K7ICT1   K7I2A3   K7ICT2   K7I2A1   K7H0R0   A0A023EWU8   K7H0Q9   A0A016VAS7   K7H0Q8   K7IBZ6   K7HDM2   K7HDM3   A0A0P4VWD0   K7IBZ5   A0A016WEQ1   A0A2H2JKG1   A0A2H2JKX8   A0A2H2JCS8  

KEGG

101735896    no KO assigned | (RefSeq) craniofacial development protein 2-like

GO

GO:0003964   GO:0004519   GO:0005524   GO:0035556   GO:0016021   GO:0004383   GO:0004672   GO:0016758  

Length:

1174

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.13367

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00004

outside

1  -  1174

 

 

Pi

163.592001

Theta

18.376307

Tajima's D

1.200369

CLR

1.077943

CSRT

0.719814009299535

Interpretation

Uncertain