Gene

KWMTBOMO14746  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003822

Annotation

PREDICTED:_protein_mahjong_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr24(-):14075343-14097351      View in EpiBrowser

Full name

Protein mahjong      

Alternative Name

DDB1- and CUL4-associated factor-like 1
VPRBP-like protein

Location in the cell

Nuclear   Reliability : 2.105

CDS

ATGCCAGGGGCAGAGCCAAGCCGCTGCCTACCGCAAATCGCCCTCCTTCGCTTGCAGGCCTCCAAGTCCTCGCCCGAGGAGATCCAGGAGCAGATCGAGCTGCTGCAGAGCGTGTCGTGGTCGCGCTGGGCGCCCGTGGACGAGCTGCTGGACCTGGGGGGCGTGTCGCTGCTGCTCAAGGTGGTCGGCTACGCGTACGAGTGGAACTTCAACGGCAGATCTGAGACGGTCCGGTCGGCGCTGGACGTGGTGTCGGTGTGCTGCGTGGCCCCGCGCGTGCAGCTGCTCCTCACAGAGAAGGTGGACATGAGGGACGAGGATCTGACCACGGGCGTCAATATAGTTTTAAATGCGGCAGACGGCGACATAGTGCCGGAGCCCGAAGTCCAGAAGGCGGCCCTCAACGTGCTCGTCAACTGTGTGTGCGCGCCTGTACACAGGGCCGGTACGTCAACCACCCGCTTCTCAATAACCGGTTCCAGTAGAAAAAAGACTGCCCTTAAATCCTATGAAGACGTCATACAGAAAGTGTGGGAGAGCGTTCGGACCAACAACGGTATTATGGTGCTGCTGGCGCTGATGACGGTGAAGTCGCCCATCACGGACGCGGACCGGCTGCGCGGGCTGGCGTGCCGCGCGCTGGCCGGGCTCGCGCGCTGCCCCACCGTGCGGCAGATCATATCCAAACTGCCGCTCATCACCACCTCGCAGATACAAGTGCTGATGCGCGACCCGATACTCCAAGAGAAGCGCCAGGAGCACGTGATGTTCCAGAAGTACGCGCTGGAGCTGCTGGAGCGCGTCTCCGGGAAGAGCAAGCACATGGGAGCCGAGTTCGAAACCTCATTGGCGAATATACACAAGGCAAACGTGGTGGCCCAGACGCGAATAAACTACAACGAGCGTCAGCTGCTGCAACTGGTGCAGGAGCACCTAGCGGCCCGCGGACTGCACGAGAGCGCGGCCGTGCTGCAGCGCGAGGCGGGGCTGCCTCCCCCCGCCGCCGCCGCCCCGCCGCCTCCCCCGCCGCCAGTCTACACACCCTCAACGCCCATACGGTCGCGGCTGTCCGTGTCGAGGGGCGGCGGCGCGGCGCAGCGGGACAGCGCCGACCCCAACACGCCGCACACCGACGAGGGCAGCCCGATGCCCACGGTCATCAGACTCAGGAAGCACCAGTCCCAGACCCCCGGCGTGGGCTGCCTGCAGTCGGCTTGCGAGCAGAAGCGCTCGCTGCAGAAGCAGCTGTCGGCGTGTCCGGAGCAGGGCCCGCCGCCGCAGCACCGCGTCACGCTGCACACCATCATCACCGAGTACCTGTACAACCAGCACGCGCTCTGCAAGAACCCCGTCGTCACCTGCCCGCAGTTCAACCTCTTCGAGCCCCACAAGTGCCCGGAGCCGCGCGGCGCGTGGTCGGTGGTGGGCGCGAGCGGGAACGTGGCGGCGCGCGTGTGGCGGCGCGAGCTGGGCGCGCCCGCCCCGCACCGCCGCCTCGACACGCGCCTCGCGCACGCGCACTTCGCGCCCGCGCGCACGCTGCGCCTGCAGGACGACGACGCGTACTTCACGCACACCGTGTTCCACCCGACGCAGCAGCAACTCCTGGCGGCCACCTCCTCGGGCGACATCCGAGTGTTCAATCTGTTCACGGGGGCCGAAGAGAACTCTTATCAAGTTCACGAATCTTACATTTATCATATGCAGACAAGCAGAGACGGACTTCTGTTGCTAGCGTCAGCCACCACTCCTTGGAGGCCGCTCTCCGCCCTGTGGAACATGAAGGAGTTCGAACTGCTTTTCCAGTTAGACGCCGAGGAGTACGTGGAGTTCTCGAAGATGTCCGACGACCGCATCATCGGCACCAAGGGCGAGACGGCGACGATCTTCGACACGCGCACCGGCCGCGAGCTCATGACGCTCACGCCCTCCATCAGCAACCAGTACGCGAAGAACAGGGCCGTGTTCAACCCCACCGACGAGCTGGTGCTGTCCGATGGCGTCCTCTGGGACGTGAACACCGGCAAGGAGATCCACAAGTTCGACAAACTCAACCAAACGCACAGCGGGGTCTTTCATCCGAACGGATTAGAGGTGATATCAAACACTGAAGTATGGGACCTGCGAACATTCCACCTGCTCAGGACGGTGCCGACGCTCGACAAGTCAGAGGTCATCTTCAACCCGACGTGCACCGCCCTGTACGCCGTGTTCTCGGACCAGGACCCGGAGGACAGACACCAGTTCGACACCAGCTTCAGGACCTTAGACCCGTACGACTATTCCAGTATAGCCACGATAGACGTGAAGCGGAACATATACGCGCTGAGCGTGTCGCGCTACGGCACCCAGATCTCGGTCGTCGAGAACATGGGCGAGTACGACCAGATGCAGGAGTCGTGCGTCAAGATATACGACGTGGGACGGAGGAGGGACCACGACGACGACGCGGTCTGTATATACGCAGGGGGGGGGGATCTGATGAGGATGAGGATGATGAGGCCGCGGTACGGTAGGCAGCGGCTTGGCTCCGACCCTGGCATTGCTGAAGTCCACGGGTAA

Protein

MPGAEPSRCLPQIALLRLQASKSSPEEIQEQIELLQSVSWSRWAPVDELLDLGGVSLLLKVVGYAYEWNFNGRSETVRSALDVVSVCCVAPRVQLLLTEKVDMRDEDLTTGVNIVLNAADGDIVPEPEVQKAALNVLVNCVCAPVHRAGTSTTRFSITGSSRKKTALKSYEDVIQKVWESVRTNNGIMVLLALMTVKSPITDADRLRGLACRALAGLARCPTVRQIISKLPLITTSQIQVLMRDPILQEKRQEHVMFQKYALELLERVSGKSKHMGAEFETSLANIHKANVVAQTRINYNERQLLQLVQEHLAARGLHESAAVLQREAGLPPPAAAAPPPPPPPVYTPSTPIRSRLSVSRGGGAAQRDSADPNTPHTDEGSPMPTVIRLRKHQSQTPGVGCLQSACEQKRSLQKQLSACPEQGPPPQHRVTLHTIITEYLYNQHALCKNPVVTCPQFNLFEPHKCPEPRGAWSVVGASGNVAARVWRRELGAPAPHRRLDTRLAHAHFAPARTLRLQDDDAYFTHTVFHPTQQQLLAATSSGDIRVFNLFTGAEENSYQVHESYIYHMQTSRDGLLLLASATTPWRPLSALWNMKEFELLFQLDAEEYVEFSKMSDDRIIGTKGETATIFDTRTGRELMTLTPSISNQYAKNRAVFNPTDELVLSDGVLWDVNTGKEIHKFDKLNQTHSGVFHPNGLEVISNTEVWDLRTFHLLRTVPTLDKSEVIFNPTCTALYAVFSDQDPEDRHQFDTSFRTLDPYDYSSIATIDVKRNIYALSVSRYGTQISVVENMGEYDQMQESCVKIYDVGRRRDHDDDAVCIYAGGGDLMRMRMMRPRYGRQRLGSDPGIAEVHG

Description

Probable substrate recognition component of tsome E3 ubiquitin-protein ligase complex (By similarity). Plays a key role in cell competition via its interaction with l(2)gl.

Subunit

Component of the CUL4-RBX1-DDB1-DCAF1 E3 ubiquitin-protein ligase complex (By similarity). Interacts with l(2)gl.

Similarity

Belongs to the VPRBP/DCAF1 family.

Keywords

Complete proteome   Nucleus   Phosphoprotein   Reference proteome   Ubl conjugation pathway  

Feature

chain  Protein mahjong

Uniprot

H9J2T5   A0A3S2PEH5   A0A212F5C9   A0A194Q0X0   S4PFN2   A0A2A4K1C3   + More
A0A2W1B4K3   A0A0N1IGQ8   A0A1B6JE98   A0A1B6HVS0   A0A1B6HXZ3   A0A1B6KX82   A0A1W4XG03   D6WJD4   A0A1Y1NKN0   A0A1W4XFZ8   A0A1W4XES6   V5G384   A0A146LRX2   A0A146KJI0   A0A0V0G7K2   A0A224XHV9   A0A069DY73   A0A310SLU9   A0A151WIE6   A0A1L8DWI2   A0A1L8DX79   A0A1L8DWI8   A0A1L8DXA5   E0VC91   A0A336LYJ1   E9GVW2   A0A0N8AD33   A0A0P5Q4R1   A0A0P5HDQ9   A0A0P5JXW4   A0A0P6E9P6   A0A0P5K0R4   A0A0P4Y294   A0A0N8BGJ6   A0A164KEF0   A0A0P5YES2   A0A0P6CVD7   A0A0P5NAL5   A0A0P5N8F4   A0A0P6HGP9   A0A1B0C5H1   A0A0P5QVM6   W8B521   W8B9F5   A0A3Q0IRT4   A0A0P5XZB4   A0A034VFE4   B4MNH7   B3MIX3   A0A0A1X4N0   A0A0P9AFB9   A0A0K8U154   A0A0K8V4J0   B4I7S8   B4QGH7   B4P8W5   A0A0R1DWU5   A0A0Q5VXM9   B3NMY4   A0A0R1DV61   A0A0B4K8A5   Q9W2F2   A0A1W4VPZ4   A0A1W4VCY9   L7M0D5   A0A224YRQ7   A0A224YPT5   A0A131YXE8   A0A224Z047   A0A0A9ZAR4   A0A0M3QUW0   A0A1B6G9I8   A0A3Q0HAK5   A0A3Q0HF13   A0A091K1U6   A0A151MF15   A0A093RVC2   A0A093RGY6   A0A093C7B6   A0A093P041   V9KA59   A0A091VM69   A0A091J619   H0Z380   H0Z375   A0A091LX13   U3K2R6   A0A2I0LRB5   A0A091P7E5   A0A091H9U9   A0A3L8S2Y0   A0A218UQK2   A0A087VIC8  

Pubmed

19121390    22118469    26354079    23622113    28756777    18362917    + More
19820115    28004739    26823975    26334808    20566863    21292972    24495485    25348373    17994087    25830018    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    18327897    20644714    25576852    28797301    26830274    25401762    22293439    24402279    20360741    23371554    30282656   

EMBL

BABH01036896    BABH01036897    BABH01036898    RSAL01000072    RVE49076.1    AGBW02010216    + More
OWR48909.1    KQ459580    KPI99196.1    GAIX01003947    JAA88613.1    NWSH01000242    PCG78065.1    KZ150606    PZC70461.1    KQ460735    KPJ12616.1    GECU01010211    JAS97495.1    GECU01028914    JAS78792.1    GECU01028148    JAS79558.1    GEBQ01023935    JAT16042.1    KQ971343    EFA04458.2    GEZM01000208    GEZM01000207    JAV98451.1    GALX01004001    JAB64465.1    GDHC01009469    JAQ09160.1    GDHC01021888    JAP96740.1    GECL01002033    JAP04091.1    GFTR01008795    JAW07631.1    GBGD01000098    JAC88791.1    KQ761155    OAD58169.1    KQ983097    KYQ47505.1    GFDF01003274    JAV10810.1    GFDF01003036    JAV11048.1    GFDF01003273    JAV10811.1    GFDF01003035    JAV11049.1    DS235051    EEB11013.1    UFQT01000229    SSX22081.1    GL732569    EFX76381.1    GDIP01159273    JAJ64129.1    GDIQ01125662    JAL26064.1    GDIQ01231328    JAK20397.1    GDIQ01197784    JAK53941.1    GDIQ01065835    JAN28902.1    GDIQ01217095    JAK34630.1    GDIP01233507    JAI89894.1    GDIQ01179891    JAK71834.1    LRGB01003325    KZS03192.1    GDIP01058729    JAM44986.1    GDIQ01089727    JAN05010.1    GDIQ01148412    JAL03314.1    GDIQ01148413    JAL03313.1    GDIQ01019069    JAN75668.1    JXJN01025984    GDIQ01118417    JAL33309.1    GAMC01012878    JAB93677.1    GAMC01012877    JAB93678.1    GDIP01066329    JAM37386.1    GAKP01018125    JAC40827.1    CH963848    EDW73666.2    CH902619    EDV37039.2    GBXI01008506    JAD05786.1    KPU76574.1    GDHF01032244    JAI20070.1    GDHF01018472    JAI33842.1    CH480824    EDW56653.1    CM000362    CM002911    EDX08096.1    KMY95594.1    CM000158    EDW91219.1    KRJ99713.1    CH954179    KQS62302.1    EDV55478.1    KRJ99714.1    AE013599    AFH08204.1    AY118444    BT003172    BT016025    GACK01007702    JAA57332.1    GFPF01008449    MAA19595.1    GFPF01008451    MAA19597.1    GEDV01005387    JAP83170.1    GFPF01008448    MAA19594.1    GBHO01003161    GBRD01015983    GBRD01015982    JAG40443.1    JAG49843.1    CP012524    ALC41349.1    GECZ01010674    JAS59095.1    KK542992    KFP31437.1    AKHW03006215    KYO22970.1    KL668904    KFW74704.1    KL445212    KFW95247.1    KL457592    KFV10318.1    KL224918    KFW65637.1    JW862017    AFO94534.1    KL409632    KFQ90778.1    KK501572    KFP16409.1    ABQF01031570    ABQF01031571    ABQF01031572    KK510322    KFP62869.1    AGTO01001625    AKCR02000127    PKK19967.1    KK654339    KFQ03842.1    KL530511    KFO92641.1    QUSF01000084    RLV94464.1    MUZQ01000178    OWK56034.1    KL494519    KFO12370.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000053268    UP000218220    UP000053240    + More
UP000192223    UP000007266    UP000075809    UP000009046    UP000000305    UP000076858    UP000092460    UP000079169    UP000007798    UP000007801    UP000001292    UP000000304    UP000002282    UP000008711    UP000000803    UP000192221    UP000092553    UP000189705    UP000050525    UP000053258    UP000054081    UP000053283    UP000053119    UP000007754    UP000016665    UP000053872    UP000276834    UP000197619   

PRIDE

H9J2T5    Q9W2F2   

Pfam

PF08513   LisH

Interpro

IPR006594   LisH        + More
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR016024   ARM-type_fold       
IPR033270   VPRBP/DCAF1       
IPR036322   WD40_repeat_dom_sf       
IPR001680   WD40_repeat       
IPR011047   Quinoprotein_ADH-like_supfam       
IPR011989   ARM-like       

SUPFAM

SSF48371   SSF48371        + More
SSF50978   SSF50978       
SSF50998   SSF50998       

Gene 3D

2.130.10.10     1.25.10.10    

ProteinModelPortal

H9J2T5   A0A3S2PEH5   A0A212F5C9   A0A194Q0X0   S4PFN2   A0A2A4K1C3   + More
A0A2W1B4K3   A0A0N1IGQ8   A0A1B6JE98   A0A1B6HVS0   A0A1B6HXZ3   A0A1B6KX82   A0A1W4XG03   D6WJD4   A0A1Y1NKN0   A0A1W4XFZ8   A0A1W4XES6   V5G384   A0A146LRX2   A0A146KJI0   A0A0V0G7K2   A0A224XHV9   A0A069DY73   A0A310SLU9   A0A151WIE6   A0A1L8DWI2   A0A1L8DX79   A0A1L8DWI8   A0A1L8DXA5   E0VC91   A0A336LYJ1   E9GVW2   A0A0N8AD33   A0A0P5Q4R1   A0A0P5HDQ9   A0A0P5JXW4   A0A0P6E9P6   A0A0P5K0R4   A0A0P4Y294   A0A0N8BGJ6   A0A164KEF0   A0A0P5YES2   A0A0P6CVD7   A0A0P5NAL5   A0A0P5N8F4   A0A0P6HGP9   A0A1B0C5H1   A0A0P5QVM6   W8B521   W8B9F5   A0A3Q0IRT4   A0A0P5XZB4   A0A034VFE4   B4MNH7   B3MIX3   A0A0A1X4N0   A0A0P9AFB9   A0A0K8U154   A0A0K8V4J0   B4I7S8   B4QGH7   B4P8W5   A0A0R1DWU5   A0A0Q5VXM9   B3NMY4   A0A0R1DV61   A0A0B4K8A5   Q9W2F2   A0A1W4VPZ4   A0A1W4VCY9   L7M0D5   A0A224YRQ7   A0A224YPT5   A0A131YXE8   A0A224Z047   A0A0A9ZAR4   A0A0M3QUW0   A0A1B6G9I8   A0A3Q0HAK5   A0A3Q0HF13   A0A091K1U6   A0A151MF15   A0A093RVC2   A0A093RGY6   A0A093C7B6   A0A093P041   V9KA59   A0A091VM69   A0A091J619   H0Z380   H0Z375   A0A091LX13   U3K2R6   A0A2I0LRB5   A0A091P7E5   A0A091H9U9   A0A3L8S2Y0   A0A218UQK2   A0A087VIC8  

PDB

5AJA     E-value=4.83655e-84,     Score=796

KEGG

101735741    K11789 HIV-1 Vpr-binding protein [EC:2.7.11.1] | (RefSeq) protein mahjong

GO

GO:0016567   GO:0080008   GO:0005634   GO:0003746   GO:0035212   GO:0001650   GO:0030331   GO:0008180   GO:1990244   GO:0033151   GO:0030183   GO:0000122   GO:0005515   GO:0005488   GO:0003676   GO:0008017   GO:0006886   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR13129  

Subcellular location

Nucleus  

Length:

853

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00519999999999999

Exp number, first 60 AAs:

0.00128

Total prob of N-in:

0.00023

outside

1  -  853

 

 

Pi

223.353103

Theta

145.591299

Tajima's D

1.778428

CLR

0.051008

CSRT

0.847057647117644

Interpretation

Uncertain