Gene

KWMTBOMO14737

Pre Gene Modal

BGIBMGA003827

Annotation

PREDICTED:_ubiquitin-associated_domain-containing_protein_1_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr24(-):13908528-13912901      View in EpiBrowser

Full name

Peptidyl-prolyl cis-trans isomerase       + More
Peptide hydrolase      

Location in the cell

Extracellular   Reliability : 1.491

CDS

ATGTCAATTTATGTCCCAGGTCTGTACTGGAGTGGAGGAGACGTGATACACGACAATGGCTTCGGCTGTTACGCCCAAAGGGGAAGACGGACGCCCATCGGAGCCGAGAACTATCACTACTCACATTCTCTTCCCGGTCTTCTGTCGATGCGCGTGACAAAGGACGATGAAATGTGCGGCATATTTAATATAACCTTCAAACCGCTGCCTCAATTCGATCTACGGAACGTTGTCTTTGGAAGAGTAATTCTGCCGTGCGAGACTTTTGAAGTGATTCGCGGCTTAGGCGCCCCGCTCAGCTCGCGTCCGGTCGTGGAGATATCGGCGGCAAAACACCGCGTCGACAACCGCTGGGTGTACGGAAAGCCTAATAGTAGAATTAAAAACTGA

Protein

MSIYVPGLYWSGGDVIHDNGFGCYAQRGRRTPIGAENYHYSHSLPGLLSMRVTKDDEMCGIFNITFKPLPQFDLRNVVFGRVILPCETFEVIRGLGAPLSSRPVVEISAAKHRVDNRWVYGKPNSRIKN

Description

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Similarity

Belongs to the cyclophilin-type PPIase family.
Belongs to the peptidase M28 family.

Feature

chain  Peptidyl-prolyl cis-trans isomerase

Uniprot

A0A2H1V7R5   A0A2A4IYK9   A0A212F543   A0A194Q0T1   H9IV42   Q2F611   + More
A0A212EX06   A0A2A4JK20   A0A194RBU3   A0A3S2NYK6   A0A194QC44   A0A2H1VVT0   J9KSD8   A0A0J0XHS7   A0A099P773   A0A1Q2YAJ4   D8MAZ2   A0A1R2BFH5   L7CGQ4   Q7UMR2   K5D633   F2AX20   F2UN80   M5SCB6   M5TDW4   C5M6A0   M2AZF2   A0A1E7F4I6   A0A132A4N0   W0E0J2   A0A1B7SM77   M0SV84   A0A3M8NRN9   A0A1Y1HSP4   H2AUQ6   L1IT53   A0A090LEW7   A0A162B4Q9   F2QQD5   A0A1Q3A3R1   C5DYK2   W7TPH9   H3A5C5   A5K7K7   A0A0J9TWG5   A0A0J9W0E8   A0A0J9SG55   A0A1G4HBM6   A0A1B2JFQ6   A0A376B2U8   A0A0J9SVE3   A0A0J1B9C4   D8TPQ4   A0A1E3NGA1   A0A1E4TA10   M0U4B7   M5UGQ2   C3YR41   A0A061AWC1   K0KUU1   A0A1E3NW22   A0A287I203   A5KDH9   A0A1B1E4J5   I2JRN0   A0A0V1Q606   A0A1V2L5F3   A0A0B7FXH5   A5K4H1   A0A0J9TXW6   A0A0J9TCI7   A0A0J9V388   A0A1G4HCM3   H8Z5U6   A0A0D9WU02   A0A0N5BJH8   A0A1R2C8K2   A0A2N1J8S6   A0A1X7R6L9   A0A1J3JAS4   V7CSY1   M1UUR5   A0A165FND5   A0A165FP01  

EC Number

5.2.1.8
3.4.-.-

Pubmed

22118469    26354079    19121390    25159171    28385833    23273849    + More
12835416    19465905    26555130    27535936    22801500    24865297    22123960    23201678    21575661    27388471    19525356    23966634    9215903    18843361    20616280    18563158    25103752    23193139    23075845    27587810    22470482    15071595    17623057    26659563   

EMBL

ODYU01001120    SOQ36888.1    NWSH01005009    PCG64498.1    AGBW02010257    OWR48855.1    + More
KQ459580    KPI99192.1    BABH01000410    DQ311261    ABD36206.1    AGBW02011847    OWR46032.1    NWSH01001158    PCG72311.1    KQ460397    KPJ15308.1    RSAL01000023    RVE52282.1    KQ459439    KPJ01006.1    ODYU01004741    SOQ44939.1    ABLF02007382    ABLF02007383    ABLF02007384    ABLF02037453    ABLF02051027    KQ087230    KLT40675.1    CP028773    JQFK01000001    MQVM01000010    NHMM01000007    AWU74457.1    KGK40775.1    ONH74409.1    OUT20762.1    BDGI01000001    GAV26565.1    FN668690    CBK25231.2    MPUH01000693    OMJ75395.1    AMWG01000111    ELP32256.1    BX294148    CAD75841.1    AMCW01000067    EKK02182.1    AFAR01000210    EGF25797.1    GL832983    EGD78579.1    ANOF01000184    EMI23774.1    ANOQ01000104    EMI41953.1    GG692396    EER34520.1    ANMO01000177    EMB15364.1    KV784363    OEU13098.1    JXLN01010224    KPM05350.1    CP007031    AHF02631.1    AECK01000002    OBA17584.1    RHFJ01000033    RNE92675.1    DF237035    GAQ81654.1    HE650824    CCF58106.1    JH993041    EKX39262.1    LN609529    CEF66075.1    LSYU01000061    KXX64281.1    FR839628    CCA37613.1    BDGX01000021    GAV50365.1    CU928178    CAR28863.1    AZIL01000936    EWM25413.1    AFYH01246278    AFYH01246279    AFYH01246280    AFYH01246281    AAKM01000008    EDL44766.1    KQ235360    KMZ99969.1    KQ235038    KMZ93478.1    KQ234266    KMZ80912.1    LT615246    LT615263    LT635619    SCO66899.1    SCO72326.1    SGX77109.1    CP014586    ANZ76867.1    UFAJ01000077    SSD59008.1    KQ234811    KMZ87045.1    LECT01000038    KLU03342.1    GL378330    EFJ50807.1    KV454005    ODQ45149.1    KV453843    ODV88561.1    ANOH01000115    EMI57026.1    GG666545    EEN57283.1    LK052887    CDR38977.1    CAIF01000292    CCH46986.1    KV454215    ODQ56777.1    AAKM01000961    EDL42590.1    CP016250    ANQ09952.1    AHIQ01000260    EIF45632.1    LMYN01000004    KSA03885.1    MPUK01000006    ONH66795.1    LN679106    CEL62621.1    AAKM01000005    EDL45549.1    KQ235387    KMZ99692.1    KQ235046    KMZ93200.1    KQ234279    KMZ80403.1    LT615247    LT615264    LT635620    SCO67256.1    SCO72643.1    SGX77488.1    JH603170    EIC19580.1    MPUH01000239    OMJ85344.1    KZ454993    PKI82963.1    FXLY01000007    SMN21080.1    GEVM01016385    JAU89553.1    CM002288    ESW33224.1    AP006497    BAM81631.1    KV426077    KZV89273.1    KV426076    KZV89300.1   

Proteomes

UP000218220    UP000007151    UP000053268    UP000005204    UP000053240    UP000283053    + More
UP000007819    UP000053611    UP000029867    UP000189274    UP000195871    UP000249293    UP000010959    UP000001025    UP000007993    UP000006222    UP000007799    UP000011996    UP000012028    UP000002037    UP000011529    UP000005275    UP000078553    UP000012960    UP000274052    UP000054558    UP000005220    UP000011087    UP000035682    UP000075766    UP000006853    UP000187013    UP000008536    UP000008672    UP000008333    UP000094565    UP000036367    UP000001058    UP000094455    UP000011885    UP000001554    UP000009328    UP000094112    UP000011116    UP000054251    UP000189513    UP000059188    UP000002964    UP000032180    UP000046392    UP000232875    UP000196158    UP000000226    UP000007014    UP000077266   

PRIDE

H9IV42    Q2F611   

Pfam

PF00160   Pro_isomerase        + More
PF13879   KIAA1430
PF00638   Ran_BP1
PF04969   CS
PF04389   Peptidase_M28

Interpro

IPR002130   Cyclophilin-type_PPIase_dom        + More
IPR029000   Cyclophilin-like_dom_sf       
IPR015940   UBA       
IPR009060   UBA-like_sf       
IPR029488   Hmw/CFAP97D1       
IPR024936   Cyclophilin-type_PPIase       
IPR020892   Cyclophilin-type_PPIase_CS       
IPR011993   PH-like_dom_sf       
IPR000156   Ran_bind_dom       
IPR008978   HSP20-like_chaperone       
IPR007052   CS_dom       
IPR039373   Peptidase_M28B       
IPR007484   Peptidase_M28       
IPR034308   VPS70       

SUPFAM

SSF50891   SSF50891        + More
SSF46934   SSF46934       
SSF49764   SSF49764       

Gene 3D

2.40.100.10     2.30.29.30     2.60.40.790    

ProteinModelPortal

A0A2H1V7R5   A0A2A4IYK9   A0A212F543   A0A194Q0T1   H9IV42   Q2F611   + More
A0A212EX06   A0A2A4JK20   A0A194RBU3   A0A3S2NYK6   A0A194QC44   A0A2H1VVT0   J9KSD8   A0A0J0XHS7   A0A099P773   A0A1Q2YAJ4   D8MAZ2   A0A1R2BFH5   L7CGQ4   Q7UMR2   K5D633   F2AX20   F2UN80   M5SCB6   M5TDW4   C5M6A0   M2AZF2   A0A1E7F4I6   A0A132A4N0   W0E0J2   A0A1B7SM77   M0SV84   A0A3M8NRN9   A0A1Y1HSP4   H2AUQ6   L1IT53   A0A090LEW7   A0A162B4Q9   F2QQD5   A0A1Q3A3R1   C5DYK2   W7TPH9   H3A5C5   A5K7K7   A0A0J9TWG5   A0A0J9W0E8   A0A0J9SG55   A0A1G4HBM6   A0A1B2JFQ6   A0A376B2U8   A0A0J9SVE3   A0A0J1B9C4   D8TPQ4   A0A1E3NGA1   A0A1E4TA10   M0U4B7   M5UGQ2   C3YR41   A0A061AWC1   K0KUU1   A0A1E3NW22   A0A287I203   A5KDH9   A0A1B1E4J5   I2JRN0   A0A0V1Q606   A0A1V2L5F3   A0A0B7FXH5   A5K4H1   A0A0J9TXW6   A0A0J9TCI7   A0A0J9V388   A0A1G4HCM3   H8Z5U6   A0A0D9WU02   A0A0N5BJH8   A0A1R2C8K2   A0A2N1J8S6   A0A1X7R6L9   A0A1J3JAS4   V7CSY1   M1UUR5   A0A165FND5   A0A165FP01  

PDB

1QNG     E-value=2.84884e-07,     Score=124

KEGG

101743933    no KO assigned | (RefSeq) ubiquitin-associated domain-containing protein 1

GO

GO:0003755   GO:0016874   GO:0016021   GO:0006457   GO:0005739   GO:0006915   GO:0030437   GO:0016018   GO:0016575   GO:0005758   GO:0034967   GO:0045836   GO:0046907   GO:0005623   GO:0046872   GO:0008233   GO:0042026   GO:0051082   GO:0000413   GO:0006605   GO:0006886   GO:0005515   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR10404   PTHR10404:SF64  

Length:

129

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00744

Exp number, first 60 AAs:

0.00357

Total prob of N-in:

0.09498

outside

1  -  129

 

 

Pi

208.122377

Theta

52.141018

Tajima's D

1.231326

CLR

0.102001

CSRT

0.722613869306535

Interpretation

Uncertain