Gene

KWMTBOMO14734

Pre Gene Modal

BGIBMGA014507

Annotation

vacuolar_ATPase?_subunit_M9.7_[Manduca_sexta]

Location

Bomo_Chr24(-):13880583-13886671      View in EpiBrowser

Full name

V-type proton ATPase subunit      

Location in the cell

PlasmaMembrane   Reliability : 4.13

CDS

ATGGGCTACTCCCTTATCCCGATCTTCGTTTTCTCCATCCTTTGGGGTGTGGTTGGTATTATTTGCCCCATCTTCGCACCTAAAGGACCAAACAGAGGGATTATTCAAGTGGTGTTAATATTAACGGCAGCGACTTGTTGGTTATTTTGGCTGTGTGCTTACATGGCACAGATGAACCCTCTCATCGGGCCCAGACTCAGCAATGAAACCCTAATCTGGATTTCACGCACTTGGGGAAACAAAATAAACAACACGCAAGCTTAA

Protein

MGYSLIPIFVFSILWGVVGIICPIFAPKGPNRGIIQVVLILTAATCWLFWLCAYMAQMNPLIGPRLSNETLIWISRTWGNKINNTQA

Description

Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Subunit

Composed of at least 10 subunits.

Similarity

Belongs to the V-ATPase e1/e2 subunit family.

Feature

chain  V-type proton ATPase subunit

Uniprot

O76959   S4NWG7   A0A2A4IZ97   I4DJ12   A0A212FB25   A0A2H1VR35   + More
I4DN47   A0A2W1BHB9   A0A194R509   A0A0L7LC72   A0A1B0D3P9   U5EQM3   A0A1S3DLQ6   A0A1I8JUY2   A0A1L8DEG6   A0A084VH97   A0A2M3Z0M8   A0A2C9H8L1   A0A1I8JTR0   Q7QAP9   A0A182N4R6   A0A182QS91   Q1HRJ8   Q0IEF0   A0A2M4C3Z0   T1E2Q7   T1DRB1   A0A2M4AE41   A0A023EEI5   A0A2M4C3Y7   A0A2M4ACV5   A0A1Y9IVQ3   A0A2M4A6V4   A0A2M4AE73   A0A2M4C4U9   W5JJ96   A0A2M4CVF4   A0A0F7QZZ0   A0A2M4CVE3   A0A0L7QKJ5   D1FQ69   A0A067QXD0   J3JUH2   A0A1Q3FKU1   B0X1E3   A0A026WXW4   A0A2M4C4U3   A0A088AFI1   T1IC14   A0A0P4VWE5   G1K0S1   A0A2A3EDR7   V9IHU9   A0A0N0U7G8   A0A023F8Y7   A0A182Y7C6   A0A0V0G3W8   A0A182K8J9   A0A139WLV2   A0A158NVM9   A0A1W4X749   E0VJ42   A0A310S785   Q5MIS8   J9LV72   E2B2P9   A0A154PGW6   A0A232FB84   K7IN76   A0A195E463   A0A1B0GAE0   A0A1B0B9P9   A0A2M4B0B6   A0A151IMB7   A0A224Y280   A0A1D2NCM0   A0A146KKW7   E1ZWF8   A0A195FTQ0   R4WRA2   A0A0J7KU97   B4J1H4   F4WAG0   A0A0P6AZU9   E9GL66   A0A1J1J6B7   Q8SZ31   A0A0P5XZ98   B4LBQ3   B4H7X9   A0A1L8EFF6   A0A1W4URW7   B3NEA7   Q2VJI6   B4IAR7   B4QK61   Q9VP18   B4PDL2   Q4V4G1   A0A0L0CK79  

Pubmed

10358099    23622113    22651552    26354079    22118469    28756777    + More
26227816    24438588    12364791    14747013    17210077    17204158    17510324    24330624    24945155    26483478    20920257    23761445    25937057    24845553    22516182    23537049    24508170    30249741    27129103    21736942    25474469    25244985    18362917    19820115    21347285    20566863    17244540    20798317    28648823    20075255    27289101    26823975    23691247    17994087    21719571    21292972    16085702    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    26108605   

EMBL

AJ006029    CAA06822.1    GAIX01014665    JAA77895.1    NWSH01005009    PCG64500.1    + More
AK401280    KQ459580    BAM17902.1    KPI99190.1    AGBW02009382    OWR50944.1    ODYU01003658    SOQ42704.1    AK402715    BAM19337.1    KZ150209    PZC72216.1    KQ460685    KPJ12767.1    JTDY01001716    KOB73093.1    AJVK01011005    GANO01003210    JAB56661.1    GFDF01009266    JAV04818.1    ATLV01013150    KE524842    KFB37341.1    GGFM01001322    MBW22073.1    APCN01005538    AAAB01008888    EAA08865.3    AXCN02000015    DQ440096    ABF18129.1    CH477695    EAT37149.1    EJY57885.1    GGFJ01010844    MBW59985.1    GALA01000474    JAA94378.1    GAMD01000705    JAB00886.1    GGFK01005557    MBW38878.1    JXUM01141252    JXUM01141253    GAPW01006533    KQ569212    JAC07065.1    KXJ68715.1    GGFJ01010915    MBW60056.1    GGFK01005117    MBW38438.1    GGFK01003160    MBW36481.1    GGFK01005766    MBW39087.1    GGFJ01011134    MBW60275.1    ADMH02001019    ETN64432.1    GGFL01005135    MBW69313.1    LC026146    BAR72391.1    GGFL01005134    MBW69312.1    KQ414940    KOC59147.1    EZ419969    ACZ28324.1    KK853137    KDR10794.1    APGK01016973    BT126886    KB739995    KB630343    KB631518    AEE61848.1    ENN82012.1    ERL83547.1    ERL84340.1    GFDL01006942    JAV28103.1    DS232258    EDS38592.1    KK107072    QOIP01000007    EZA60638.1    RLU20797.1    GGFJ01011189    MBW60330.1    ACPB03001840    GDKW01002676    JAI53919.1    JO495153    AEL79382.1    KZ288287    PBC29369.1    JR046707    AEY60237.1    KQ435710    KOX79728.1    GBBI01000805    JAC17907.1    GECL01003379    JAP02745.1    KQ971316    KYB28989.1    ADTU01027288    DS235219    EEB13398.1    KQ780658    OAD51929.1    AY826132    AAV90704.1    ABLF02013158    GL445210    EFN90031.1    KQ434902    KZC11105.1    NNAY01000480    OXU28091.1    KQ979701    KYN19644.1    CCAG010011415    JXJN01010515    GGFK01013165    MBW46486.1    KQ977085    KYN05906.1    GFTR01001673    JAW14753.1    LJIJ01000090    ODN02992.1    GDHC01021398    JAP97230.1    GL434829    EFN74481.1    KQ981281    KYN43269.1    AK417197    BAN20412.1    LBMM01003062    KMQ94012.1    CH916366    EDV95865.1    GL888048    EGI68843.1    GDIP01023001    LRGB01002190    JAM80714.1    KZS08703.1    GL732550    EFX79846.1    CVRI01000072    CRL07514.1    AY071161    AAL48783.1    GDIP01065273    JAM38442.1    CH940647    EDW68680.1    CH479219    EDW34769.1    GFDG01001381    JAV17418.1    CH954178    EDV52671.1    DQ079536    AAZ43020.1    CH480826    EDW44380.1    CM000363    CM002912    EDX11398.1    KMZ01039.1    AE014296    BT032649    AAF51743.2    ACD81663.1    CM000159    EDW95011.1    EDW95016.1    BT023045    AAY55461.2    JRES01000296    KNC32666.1   

Proteomes

UP000218220    UP000053268    UP000007151    UP000053240    UP000037510    UP000092462    + More
UP000079169    UP000075900    UP000030765    UP000076407    UP000075840    UP000007062    UP000075884    UP000075886    UP000008820    UP000069940    UP000249989    UP000075920    UP000000673    UP000053825    UP000027135    UP000019118    UP000030742    UP000002320    UP000053097    UP000279307    UP000005203    UP000015103    UP000242457    UP000053105    UP000076408    UP000075881    UP000007266    UP000005205    UP000192223    UP000009046    UP000007819    UP000008237    UP000076502    UP000215335    UP000002358    UP000078492    UP000092444    UP000092460    UP000078542    UP000094527    UP000000311    UP000078541    UP000036403    UP000001070    UP000007755    UP000076858    UP000000305    UP000183832    UP000008792    UP000008744    UP000192221    UP000008711    UP000001292    UP000000304    UP000000803    UP000002282    UP000037069   

PRIDE

Q8SZ31    Q4V4G1   

Pfam

PF05493   ATP_synt_H        + More
PF03540   TFIID_30kDa
PF00587   tRNA-synt_2b
PF03129   HGTP_anticodon
PF10601   zf-LITAF-like

Interpro

IPR017385   ATPase_V0-cplx_e1/e2_su_met        + More
IPR008389   ATPase_V0-cplx_e1/e2_su       
IPR003923   TFIID_30kDa       
IPR004154   Anticodon-bd       
IPR033730   ProRS_core_prok       
IPR006195   aa-tRNA-synth_II       
IPR002314   aa-tRNA-synt_IIb       
IPR036621   Anticodon-bd_dom_sf       
IPR002316   Pro-tRNA-ligase_IIa       
IPR037519   LITAF_fam       
IPR006629   LITAF       

Gene 3D

3.40.50.800    

CDD

cd07982  TAF10
cd00779  ProRS_core_prok

ProteinModelPortal

O76959   S4NWG7   A0A2A4IZ97   I4DJ12   A0A212FB25   A0A2H1VR35   + More
I4DN47   A0A2W1BHB9   A0A194R509   A0A0L7LC72   A0A1B0D3P9   U5EQM3   A0A1S3DLQ6   A0A1I8JUY2   A0A1L8DEG6   A0A084VH97   A0A2M3Z0M8   A0A2C9H8L1   A0A1I8JTR0   Q7QAP9   A0A182N4R6   A0A182QS91   Q1HRJ8   Q0IEF0   A0A2M4C3Z0   T1E2Q7   T1DRB1   A0A2M4AE41   A0A023EEI5   A0A2M4C3Y7   A0A2M4ACV5   A0A1Y9IVQ3   A0A2M4A6V4   A0A2M4AE73   A0A2M4C4U9   W5JJ96   A0A2M4CVF4   A0A0F7QZZ0   A0A2M4CVE3   A0A0L7QKJ5   D1FQ69   A0A067QXD0   J3JUH2   A0A1Q3FKU1   B0X1E3   A0A026WXW4   A0A2M4C4U3   A0A088AFI1   T1IC14   A0A0P4VWE5   G1K0S1   A0A2A3EDR7   V9IHU9   A0A0N0U7G8   A0A023F8Y7   A0A182Y7C6   A0A0V0G3W8   A0A182K8J9   A0A139WLV2   A0A158NVM9   A0A1W4X749   E0VJ42   A0A310S785   Q5MIS8   J9LV72   E2B2P9   A0A154PGW6   A0A232FB84   K7IN76   A0A195E463   A0A1B0GAE0   A0A1B0B9P9   A0A2M4B0B6   A0A151IMB7   A0A224Y280   A0A1D2NCM0   A0A146KKW7   E1ZWF8   A0A195FTQ0   R4WRA2   A0A0J7KU97   B4J1H4   F4WAG0   A0A0P6AZU9   E9GL66   A0A1J1J6B7   Q8SZ31   A0A0P5XZ98   B4LBQ3   B4H7X9   A0A1L8EFF6   A0A1W4URW7   B3NEA7   Q2VJI6   B4IAR7   B4QK61   Q9VP18   B4PDL2   Q4V4G1   A0A0L0CK79  

KEGG

101746782    K02153 V-type H+-transporting ATPase subunit e | (RefSeq) V-type proton ATPase subunit e 2-like

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04145    Phagosome - Bombyx mori (domestic silkworm)

GO

GO:0016787   GO:0015991   GO:0033179   GO:0016021   GO:0015078   GO:0006352   GO:0005634   GO:0003743   GO:0055085   GO:0005524   GO:0005737   GO:0004827   GO:0006433   GO:0033181   GO:0000220   GO:0006605   GO:0006886   GO:0005515   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR12263   PTHR21242   PTHR23292  

Subcellular location

Membrane  

Length:

87

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

44.30754

Exp number, first 60 AAs:

44.28916

Total prob of N-in:

0.55459

POSSIBLE N-term signal

sequence

inside

1  -  4

TMhelix

5  -  27

outside

28  -  31

TMhelix

32  -  54

inside

55  -  87

 

 

Pi

221.483274

Theta

179.269024

Tajima's D

0.715281

CLR

0.047288

CSRT

0.582020898955052

Interpretation

Uncertain