Gene

KWMTBOMO14731

Pre Gene Modal

BGIBMGA003828

Annotation

Transcription_initiation_factor_TFIID_subunit_10_[Operophtera_brumata]

Location

Bomo_Chr24(-):13841545-13843957      View in EpiBrowser

Full name

Transcription initiation factor TFIID subunit 10      

Alternative Name

Transcription initiation factor TFIID 30 kDa subunit

Location in the cell

Extracellular   Reliability : 1.59 Nuclear   Reliability : 2.246

CDS

ATGAGCCGTATCGGTTCACCATCGGTCGGTATGGACGACGACGGTTGCGCAGGACACGCTTTAGGCGACTTCCTTCTTCAGCTTGAGAATTATAATCCATCCATACCCGATTCCGTGGTCGCATATTATTTGAATTTAACCGGATTCGAGTCACAGGATCCGAGACTTGTCAGATTGATCGCATTGGCATCACAGAAATTCTTATCTGACATTGTAAATGATGCACTGCAGCACTGCAAGATGCGTACGTCGAATCAAATAAATCAAAGCTCCAAAAACCAGAAGGGACCCAAAGAGAAGAAATATGTCATGACCATGGACGATTTGGCTCCCGCGTTACAAGAGTATGGCATAACAGCAAAGAAACCGCACTATTTTGTTTGA

Protein

MSRIGSPSVGMDDDGCAGHALGDFLLQLENYNPSIPDSVVAYYLNLTGFESQDPRLVRLIALASQKFLSDIVNDALQHCKMRTSNQINQSSKNQKGPKEKKYVMTMDDLAPALQEYGITAKKPHYFV

Description

TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May regulate cyclin E expression.

Subunit

TFIID and PCAF are composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TBP is not part of TFTC. Component of the PCAF complex, at least composed of TADA2L/ADA2, TADA3L/ADA3, SUPT3H, TAF5L, TAF6L, TAF9, TAF10, TAF12 and TRRAP. Component of the TFTC-HAT complex, at least composed of TAF5L, TAF6L, TADA3L, SUPT3H, TAF2, TAF4, TAF5, GCN5L2/GCN5, TAF10 and TRRAP. Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9. The STAGA core complex is associated with a subcomplex required for histone deubiquitination composed of ATXN7L3, ENY2 and USP22 (By similarity). Interacts with TAF3 (PubMed:11438666). Interacts with LOXL2 (By similarity).

Similarity

Belongs to the TAF10 family.

Keywords

Acetylation   Complete proteome   Methylation   Nucleus   Phosphoprotein   Reference proteome   Transcription   Transcription regulation  

Feature

chain  Transcription initiation factor TFIID subunit 10

Uniprot

H9J2U1   A0A2W1BET2   A0A2A4J0N3   A0A0L7KEB0   S4P4X4   A0A2H1WBD8   + More
A0A1E1W6M4   A0A194Q1I7   A0A194R509   A0A2J7PYT2   A0A0K8TPT8   C3XPP3   A0A1B0DH81   A0A1Q3FG34   J3JZ71   B0WUQ2   A0A182P4B1   R4ULY9   A0A182SKC6   A0A023EFC4   A0A067RI97   A0A1I8PU81   A0A182RK78   W5JT55   Q178Y1   A0A182QJ97   A0A084VFE4   A0A182NTD3   A0A2T7PPV3   A0A2B4RQR4   A0A182J3M2   A0A182WFJ1   A0A182V0V2   A0A182U5A3   Q7Q8I7   A0A182F0T6   A0A3N0YT46   A0A2M3Z4H5   Q1LVD6   Q1LVD5   M9VAC9   U5EQC9   A0A2M4C2X1   A0A182X5Y8   A0A182YQI3   A0A182KN82   A0A1A8DTE1   A0A1A8UYN2   A0A1A8QV20   A0A1A8JZU8   C1BLB8   A0A0P7WH99   A0A1A7XWE6   A0A1W4XXH4   A0A0L8FHD8   A0A0E9WVK1   C1BH11   W5M3F8   A0A1A8EX70   C1BIA8   B5X8E6   H3D363   Q8K0H5   A0A3S3P410   A0A1L8DGY8   A0A1B6D4A5   A0A060YFI9   H2UQS7   A0A1A8L6I8   F7FRQ9   A0A3B1JZM9   A0A093F905   A0A1A6HQN7   G7NE05   G1SRB2   A0A093KGM3   A0A091U720   A0A087VEB8   A0A091LHN5   A0A091JJP1   A0A341CE20   A0A091V8A0   R7V2A5   A0A091TRJ8   A0A094KSU6   A0A1B0FR10   A0A151MYK0   G3U484   A0A093Q2L5   A0A2M4AM13   C1BY99   B5X692   A0A3P8XLE2   A0A091LSB3   D2HR58   V4BRI6   C1BEY2   B4F7B2   A0A091D2J5  

Pubmed

19121390    28756777    26227816    23622113    26354079    26369729    + More
18563158    22516182    24945155    26483478    24845553    20920257    23761445    17510324    24438588    12364791    14747013    17210077    23594743    25244985    20966253    25613341    24755649    20433749    15496914    10469660    16141072    15489334    11438666    21183079    25959397    21551351    17495919    25329095    22002653    21993624    23254933    22293439    25069045    20010809    15057822    15632090   

EMBL

BABH01036846    KZ150209    PZC72214.1    NWSH01004536    PCG64972.1    JTDY01010031    + More
KOB61647.1    GAIX01011005    JAA81555.1    ODYU01007535    SOQ50391.1    GDQN01008447    GDQN01008375    JAT82607.1    JAT82679.1    KQ459580    KPI99188.1    KQ460685    KPJ12767.1    NEVH01020342    PNF21507.1    GDAI01001460    JAI16143.1    GG666451    EEN69914.1    AJVK01060754    GFDL01008531    JAV26514.1    BT128552    AEE63509.1    DS232108    EDS35038.1    KC632286    AGM32100.1    JXUM01085952    GAPW01005591    GAPW01005590    KQ563535    JAC08007.1    KXJ73700.1    KK852496    KDR22733.1    ADMH02000444    ETN66463.1    CH477357    EAT42761.1    AXCN02000713    ATLV01012384    KE524787    KFB36688.1    PZQS01000002    PVD35452.1    LSMT01000337    PFX19951.1    AAAB01008944    EAA10055.4    RJVU01027559    ROL49180.1    GGFM01002663    MBW23414.1    BX784025    BC133967    AAI33968.1    KC161218    AGJ76546.1    GANO01004309    JAB55562.1    GGFJ01010512    MBW59653.1    HADZ01010919    HAEA01008757    SBQ37237.1    HADY01008418    HAEJ01012728    SBS53185.1    HAEH01005124    HAEI01006277    SBR96879.1    HAED01018681    HAEE01005486    SBR25506.1    BT075397    ACO09821.1    JARO02008277    KPP62928.1    HADW01018001    HADX01000225    SBP22457.1    KQ431609    KOF63085.1    GBXM01014148    JAH94429.1    BT073890    ACO08314.1    AHAT01009638    HAEB01003917    HAEC01008597    SBQ50444.1    BT074337    FR904730    ACO08761.1    CDQ70660.1    BT047315    ACI67116.1    AK047115    AJ249987    BC031418    BC080311    NCKU01004553    NCKU01003389    NCKU01003365    RWS05779.1    RWS07612.1    RWS07664.1    GFDF01008366    JAV05718.1    GEDC01019107    GEDC01018820    GEDC01016767    GEDC01008178    GEDC01004600    GEDC01000355    JAS18191.1    JAS18478.1    JAS20531.1    JAS29120.1    JAS32698.1    JAS36943.1    FR908228    CDQ87910.1    HAEF01002614    HAEG01004191    SBR39996.1    KK619954    KFV50669.1    LZPO01017338    OBS80571.1    CM001266    EHH23133.1    AAGW02008015    KK585888    KFV96980.1    KK419672    KFQ86256.1    KL490132    KFO10960.1    KL320753    KFP54823.1    KK502044    KFP19965.1    KL410773    KFQ99531.1    AMQN01005350    KB295796    ELU12612.1    KK464421    KFQ80984.1    KL267029    KFZ62308.1    CCAG010010711    AKHW03004616    KYO29617.1    KL415783    KFW80650.1    GGFK01008499    MBW41820.1    BT079578    ACO14002.1    BT046561    BT047939    BT125391    ACI66362.1    ACI67740.1    ADM16132.1    KK509003    KFP62398.1    GL193208    EFB14163.1    KB202283    ESO91494.1    BT073161    ACO07585.1    AABR07071958    BC168203    CH473956    AAI68203.1    EDM18002.1    KN123504    KFO24718.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053268    UP000053240    UP000235965    + More
UP000001554    UP000092462    UP000002320    UP000075885    UP000075901    UP000069940    UP000249989    UP000027135    UP000095300    UP000075900    UP000000673    UP000008820    UP000075886    UP000030765    UP000075884    UP000245119    UP000225706    UP000075880    UP000075920    UP000075903    UP000075902    UP000007062    UP000069272    UP000000437    UP000076407    UP000076408    UP000075882    UP000034805    UP000192224    UP000053454    UP000018468    UP000193380    UP000087266    UP000007303    UP000000589    UP000285301    UP000005226    UP000002280    UP000018467    UP000092124    UP000001811    UP000053119    UP000252040    UP000053283    UP000014760    UP000092444    UP000050525    UP000007646    UP000265140    UP000030746    UP000002494    UP000028990   

PRIDE

H9J2U1    Q8K0H5   

Pfam

PF03540   TFIID_30kDa        + More
PF05493   ATP_synt_H

Interpro

IPR003923   TFIID_30kDa        + More
IPR009072   Histone-fold       
IPR008389   ATPase_V0-cplx_e1/e2_su       

Gene 3D

1.10.20.10    

CDD

cd07982  TAF10

ProteinModelPortal

H9J2U1   A0A2W1BET2   A0A2A4J0N3   A0A0L7KEB0   S4P4X4   A0A2H1WBD8   + More
A0A1E1W6M4   A0A194Q1I7   A0A194R509   A0A2J7PYT2   A0A0K8TPT8   C3XPP3   A0A1B0DH81   A0A1Q3FG34   J3JZ71   B0WUQ2   A0A182P4B1   R4ULY9   A0A182SKC6   A0A023EFC4   A0A067RI97   A0A1I8PU81   A0A182RK78   W5JT55   Q178Y1   A0A182QJ97   A0A084VFE4   A0A182NTD3   A0A2T7PPV3   A0A2B4RQR4   A0A182J3M2   A0A182WFJ1   A0A182V0V2   A0A182U5A3   Q7Q8I7   A0A182F0T6   A0A3N0YT46   A0A2M3Z4H5   Q1LVD6   Q1LVD5   M9VAC9   U5EQC9   A0A2M4C2X1   A0A182X5Y8   A0A182YQI3   A0A182KN82   A0A1A8DTE1   A0A1A8UYN2   A0A1A8QV20   A0A1A8JZU8   C1BLB8   A0A0P7WH99   A0A1A7XWE6   A0A1W4XXH4   A0A0L8FHD8   A0A0E9WVK1   C1BH11   W5M3F8   A0A1A8EX70   C1BIA8   B5X8E6   H3D363   Q8K0H5   A0A3S3P410   A0A1L8DGY8   A0A1B6D4A5   A0A060YFI9   H2UQS7   A0A1A8L6I8   F7FRQ9   A0A3B1JZM9   A0A093F905   A0A1A6HQN7   G7NE05   G1SRB2   A0A093KGM3   A0A091U720   A0A087VEB8   A0A091LHN5   A0A091JJP1   A0A341CE20   A0A091V8A0   R7V2A5   A0A091TRJ8   A0A094KSU6   A0A1B0FR10   A0A151MYK0   G3U484   A0A093Q2L5   A0A2M4AM13   C1BY99   B5X692   A0A3P8XLE2   A0A091LSB3   D2HR58   V4BRI6   C1BEY2   B4F7B2   A0A091D2J5  

PDB

6MZM     E-value=8.61965e-34,     Score=352

KEGG

101743500    K03134 transcription initiation factor TFIID subunit 10 | (RefSeq) transcription initiation factor T

PATHWAY

03022    Basal transcription factors - Bombyx mori (domestic silkworm)

GO

GO:0005634   GO:0006352   GO:0003743   GO:0046982   GO:0015991   GO:0033179   GO:0016021   GO:0015078   GO:0000125   GO:0005654   GO:0051101   GO:0051260   GO:0005737   GO:0004402   GO:0006355   GO:0016578   GO:0001889   GO:0033276   GO:0003677   GO:0019899   GO:0006915   GO:0070365   GO:0016251   GO:0006367   GO:0030914   GO:0005669   GO:0070063   GO:0010468   GO:0043966   GO:0034622   GO:0000082   GO:0035264   GO:0030331   GO:0048471   GO:0017038   GO:0006605   GO:0006886   GO:0005515   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR21242  

Subcellular location

Nucleus  

Length:

127

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00246

Exp number, first 60 AAs:

0.00184

Total prob of N-in:

0.09035

outside

1  -  127

 

 

Pi

178.563315

Theta

42.101337

Tajima's D

2.114181

CLR

0.147034

CSRT

0.901704914754262

Interpretation

Uncertain