Gene

KWMTBOMO14725

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr24(-):13764965-13767557      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.874

CDS

ATGGCGTGCAACGCGAGATTAAAACCCCATTCCTTGAAGTTAGCATTCTACAATGCTAACGGACTCGCGCGTCAGCGCGACCAGGTTTATGAGTTTCTACGTGACAATCTCATCGACATCCTTCTGGTGCAGGAGACCTTCCTAAAGCCCTCGCGTCGCGACCCCAAAGTCGCGAATTACGTCATGGTTAGGAATGACAGACTCTCCACCCGCAAGGGCGGGACTGTCATTTACTATAGGAGGGCCCTGCACTGCGTCCCTCTCGATACTCCCTCGCTCTTACATATCGAGGCGTCAGTGTGCCGCATCGCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCTGACAAACCCCTCCTGAGCAGTGACCTCGAGACACTGCTCGGTATGGGGGACGCGGTCATTCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGCACGAATGTGAACGGTAGGCGTCTCGACGCGTTCATAGACGACCTCACATTCGAGATATTCAACCCTCCGACCCCCACGTGCTATCCGTACAACGCCGCGCGTCGTCCGAGCACAATAGATCTGGCACTGCTGAGGAACGTAACTCTGCGCTTGCGCTCCATCGAGGCAATGTCAGAACTCGACTCAGACCACCGACCTGTCGTCATGCAGCTCGGTCGCCCACTCAACCGCGAACCAGATACGAGGACCATGGTGGATTGGAAGAAGCTGGGCACGTGCTTAGCTGACACCGCTCCACCAATCCTCCCTTGCGGCCCGGATTCAACTCCATCCCCCGAGGACACCGTCGAATCCATAAACATCTTCACTGATCACGTCTCGACGGCGATCACAAGATCTTCAAAGCAAGTCGATGTGGAGGACTGCTTCCACCGCATCAGACTTTCCCCCGATCTTAGGGACCTCGTAAGAGTTAGAAACGCGGCAATCCGGGCCTACGATCGATATCCCACGGATTCAAACCGGACTCGGATGCGTCGCTTACAGCGGGAGGTCAAATCCCGCTTGAGCGACGCCCGAAACGAAAACTGGGATAGTTATTTAAAAGAACTCGCGCCCACTCACCAAGCATACTGGCGACTAGCTAGGACCCTCAAGTCCGAAACTATCGTCACTATGCCGCCTCTCGTACGCCCCTCAGGCCAACCACCGGCTTACGATGACGATGACAAGGCAGAGTTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTCGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTTCCGAGGTTAAGGAGGCGATCGATAGCCTACAACCACGGAAAGCTCCCGGCTCCGACGGCATCCGCAACCGCGCGCTTAAATTGTTACCAGCCCAACTGATAACGATGTTGGCCACCATACTAAATGCTGCTATGACGAACTGCATCTTTCCCGCGGCGTGGAAAGAAGCGGACGTTATCGGCATACACAAGCCGGGCAAACCGAATAACGAAACCGCGAGTTACCGCCCCATCAGTCTCCTCCCGGCGATAGGCAAACTATACGAACGGCTCCTTCGTAAACGCCTCTGGGACTTCGTATCCGCGAACAAAATTCTGATAGACGAGCAGTTTGGATTCCGCGCCAGACACTCGTGCGTCCATCAAGTGCACCGCCTCACGGAGCACATCTTACTAGGGCTGAACAGGCGGAAACCCATTCCGACAGGAGCCCTCTTCTTCGATATAGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTGATATACAAACTGTATAACATGGGAGTGCCAGACAGGCTCGTGCTCATCATACGAGACTACTTGTCGAACCGTTCGTTCCGATATCGAGTCGAGGGAACGCGTTCCCGGCCCCGTCACGTCACAGCCCGCAAGGCTCCGCCCTCTCCCCGTTACTATTCAGTTTGTATATCAACGATATACCCCGGTCTCCGGAGACCCATCTGGCGCTCTTCGCCGATGACACCGCCATCTACTACTCGTGTAGGAAGAAGGCGTTGCTTCATCGACGACTTCAGACCGCAGCTACCACCATGGGACAGTGGTTCCGGAAGTGGCGCATCGACATCAACCCTACGAAAAGCACAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAACACCACGCTGA

Protein

MACNARLKPHSLKLAFYNANGLARQRDQVYEFLRDNLIDILLVQETFLKPSRRDPKVANYVMVRNDRLSTRKGGTVIYYRRALHCVPLDTPSLLHIEASVCRIALTGHQPIVIASVYLPPDKPLLSSDLETLLGMGDAVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEIFNPPTPTCYPYNAARRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPLNREPDTRTMVDWKKLGTCLADTAPPILPCGPDSTPSPEDTVESINIFTDHVSTAITRSSKQVDVEDCFHRIRLSPDLRDLVRVRNAAIRAYDRYPTDSNRTRMRRLQREVKSRLSDARNENWDSYLKELAPTHQAYWRLARTLKSETIVTMPPLVRPSGQPPAYDDDDKAELLADALQEQCTTSTQHADPEHTEFVDREVERRASLPPSDALPPITTSEVKEAIDSLQPRKAPGSDGIRNRALKLLPAQLITMLATILNAAMTNCIFPAAWKEADVIGIHKPGKPNNETASYRPISLLPAIGKLYERLLRKRLWDFVSANKILIDEQFGFRARHSCVHQVHRLTEHILLGLNRRKPIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDYLSNRSFRYRVEGTRSRPRHVTARKAPPSPRYYSVCISTIYPGLRRPIWRSSPMTPPSTTRVGRRRCFIDDFRPQLPPWDSGSGSGASTSTLRKAQRCSSKGVALRTPR

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q93137   Q9XXW0   Q9BPQ0   O96546   A0A0N1PFV1   A0A139W8G9   + More
A0A1Y1NA23   D7EM17   A0A139WA11   A0A023EYS8   A0A2S2QEE0   A0A1Y1K0C8   A0A2M4CV42   A0A2S2PPK8   A0A2M4CV52   Q07995   V9H092   V5GNJ2   A0A2J7R7D0   A0A2S2NCK2   A0A2S2PEZ9   A0A2S2Q383   A0A023EZE6   A0A1B0CHA5   A0A2S2NJB5   A0A087UGF5   A0A2M4BD66   A0A2S2PA10   A0A1B6C2V8   A0A2M4BD62   A0A2M4BDA5   J9LFC9   A0A2J7QR37   A0A2J7PU96   A0A2J7PBY3   A0A2J7QY69   A0A232ENU1   A0A2S2P6S3   A0A2S2PJ52   X1WZH0   A0A2J7RE85   A0A087U3K8   J9KLB1   A0A2S2R9D4   J9LC21   A0A2S2P698   A0A2S2NPG3   A0A2S2Q2R8   A0A2S2NGV8   A0A087THU2   A0A224XB44   V5GNF3   X1WVL6   A0A224X6Q4   A0A0H3UA66   A0A2S2N6Q7   A0A2S2PJG2   A0A2J7Q6J2   A0A087UCW3   A0A2J7PP17   D7GYA5   A0A2J7QB68   K7IN67   X1WLB2   A0A224X6S1   A0A224X6R6   A0A2M4CVF1   A0A2M4CVK2   A0A2S2QDN9   A0A1Y1KFT3   A0A2A4IUM2   A0A224XHW8   A0A087T3W0   A0A069DX78   A0A2S2N814   P21329   A0A224XF24   A0A1Y1KFR3   A0A1W7R682  

EC Number

2.7.7.49

Pubmed

10333566    10380107    26354079    18362917    19820115    28004739    + More
25474469    8387152    9061921    28648823    26812285    20075255    26334808    1701254   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
AF081103    AAC72921.1    KQ459265    KPJ02064.1    KQ973342    KXZ75569.1    GEZM01008457    JAV94772.1    KQ973412    EFA12510.2    KQ971729    KYB24751.1    GBBI01004395    JAC14317.1    GGMS01006359    MBY75562.1    GEZM01099921    GEZM01099920    GEZM01099918    GEZM01099906    JAV53125.1    GGFL01005012    MBW69190.1    GGMR01018716    MBY31335.1    GGFL01004957    MBW69135.1    S59870    AAB26437.2    L79944    AAB04627.1    GALX01005299    JAB63167.1    NEVH01006736    PNF36716.1    GGMR01002322    MBY14941.1    GGMR01015412    MBY28031.1    GGMS01002992    MBY72195.1    GBBI01004571    JAC14141.1    AJWK01012157    GGMR01004661    MBY17280.1    KK119692    KFM76444.1    GGFJ01001844    MBW50985.1    GGMR01013409    MBY26028.1    GEDC01029594    JAS07704.1    GGFJ01001843    MBW50984.1    GGFJ01001842    MBW50983.1    ABLF02023911    NEVH01011985    PNF31054.1    NEVH01021205    PNF19912.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    NNAY01003095    OXU19992.1    GGMR01012443    MBY25062.1    GGMR01016297    MBY28916.1    ABLF02034467    NEVH01005277    PNF39135.1    KK118005    KFM71947.1    ABLF02040174    ABLF02040183    ABLF02055266    GGMS01017365    MBY86568.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GGMR01012305    MBY24924.1    GGMR01006408    MBY19027.1    GGMS01002786    MBY71989.1    GGMR01003407    MBY16026.1    KK115285    KFM64681.1    GFTR01008262    JAW08164.1    GALX01005359    JAB63107.1    ABLF02042385    GFTR01008279    JAW08147.1    KF280391    AIE77315.1    GGMR01000226    MBY12845.1    GGMR01016905    MBY29524.1    NEVH01017470    PNF24199.1    KK119261    KFM75202.1    NEVH01023280    PNF18085.1    KQ973363    EFA13335.2    NEVH01016302    PNF25823.1    ABLF02042518    ABLF02057746    GFTR01008271    JAW08155.1    GFTR01008269    JAW08157.1    GGFL01005122    MBW69300.1    GGFL01005121    MBW69299.1    GGMS01006655    MBY75858.1    GEZM01084970    JAV60359.1    NWSH01007753    PCG62823.1    GFTR01008254    JAW08172.1    KK113281    KFM59799.1    GBGD01000389    JAC88500.1    GGMR01000676    MBY13295.1    M38437    GFTR01008038    JAW08388.1    GEZM01084969    JAV60363.1    GEHC01000968    JAV46677.1   

Proteomes

UP000053268    UP000007266    UP000235965    UP000092461    UP000054359    UP000007819    + More
UP000215335    UP000002358    UP000218220   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    P21329   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   O96546   A0A0N1PFV1   A0A139W8G9   + More
A0A1Y1NA23   D7EM17   A0A139WA11   A0A023EYS8   A0A2S2QEE0   A0A1Y1K0C8   A0A2M4CV42   A0A2S2PPK8   A0A2M4CV52   Q07995   V9H092   V5GNJ2   A0A2J7R7D0   A0A2S2NCK2   A0A2S2PEZ9   A0A2S2Q383   A0A023EZE6   A0A1B0CHA5   A0A2S2NJB5   A0A087UGF5   A0A2M4BD66   A0A2S2PA10   A0A1B6C2V8   A0A2M4BD62   A0A2M4BDA5   J9LFC9   A0A2J7QR37   A0A2J7PU96   A0A2J7PBY3   A0A2J7QY69   A0A232ENU1   A0A2S2P6S3   A0A2S2PJ52   X1WZH0   A0A2J7RE85   A0A087U3K8   J9KLB1   A0A2S2R9D4   J9LC21   A0A2S2P698   A0A2S2NPG3   A0A2S2Q2R8   A0A2S2NGV8   A0A087THU2   A0A224XB44   V5GNF3   X1WVL6   A0A224X6Q4   A0A0H3UA66   A0A2S2N6Q7   A0A2S2PJG2   A0A2J7Q6J2   A0A087UCW3   A0A2J7PP17   D7GYA5   A0A2J7QB68   K7IN67   X1WLB2   A0A224X6S1   A0A224X6R6   A0A2M4CVF1   A0A2M4CVK2   A0A2S2QDN9   A0A1Y1KFT3   A0A2A4IUM2   A0A224XHW8   A0A087T3W0   A0A069DX78   A0A2S2N814   P21329   A0A224XF24   A0A1Y1KFR3   A0A1W7R682  

KEGG

105842435    no KO assigned | (RefSeq) uncharacterized LOC105842435

GO

GO:0003964   GO:0004519   GO:0016021   GO:0008270   GO:0003676  

Length:

737

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.749699999999999

Exp number, first 60 AAs:

0.00032

Total prob of N-in:

0.00205

outside

1  -  737

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0.243645

CSRT

0

Interpretation

Uncertain