Gene

KWMTBOMO14686  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009618

Annotation

PREDICTED:_grpE_protein_homolog?_mitochondrial_[Amyelois_transitella]

Location

Bomo_Chr24(+):12685967-12691663      View in EpiBrowser

Full name

GrpE protein homolog       + More
GrpE protein homolog, mitochondrial      

Alternative Name

dRoe1

Location in the cell

Mitochondrial   Reliability : 2.707

CDS

ATGGCTCTAAAAGCTTATACATTTGGGAGAATAGCAAAATACTTGGCGGATACCACGCTGAGACCAAATCTAACGATCAAAACTTTCAGACCATCCGTTCGTGCGCTCAGTGCAGAGAAGCCAGCCGAGTCGGAGTCAAATGACAAGCTCCCGGCCACCATAGAGGAATGTCATAAACAAATTGAAAGTTTGACTAATGAAGTTAATTCTATTAAAGAACAATTCAATGACATTAATGACAAATACAAGAGAGCGTTAGCGGACGGCGAGAATGTACGGAAGAGGATGTTGAAACAAGTCGAAGACGCTAAGTCCTTTGCCATACAGAGCTTCTGCAAGGATCTGCTAGAGGTAGCAGACACATTGACGGCTGCAGCAGAGAGCATACCAGAGGGAGCGGGGGCGGAGGCCGAGGGCGGCGCCCTACGAGCCCTGCACGACGGTGTGCGACTCACGAGGGCTCAACTAGGACAGGTGTTCGCGCGGCACGGCCTGGTCCCGGTGTCTCCCCTCCGAGAGAAATTCGACCCGAATCTACATGAAGCATTGTTCCAGCAGGAAGTGGAGGGCGCCGAGTCAGGCACAGTGGTGGCCGTCAGCAAGGTCGGCTACAAACTGCACGAGAGATGCGTCAGACCAGCTTTGGTTGGGGTGGCGAAATAA

Protein

MALKAYTFGRIAKYLADTTLRPNLTIKTFRPSVRALSAEKPAESESNDKLPATIEECHKQIESLTNEVNSIKEQFNDINDKYKRALADGENVRKRMLKQVEDAKSFAIQSFCKDLLEVADTLTAAAESIPEGAGAEAEGGALRALHDGVRLTRAQLGQVFARHGLVPVSPLREKFDPNLHEALFQQEVEGAESGTVVAVSKVGYKLHERCVRPALVGVAK

Description

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).

Subunit

Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, Roe1, TIM44, blp/TIM16 and TIM14.

Similarity

Belongs to the GrpE family.

Keywords

Chaperone   Complete proteome   Mitochondrion   Reference proteome   Transit peptide  

Feature

chain  GrpE protein homolog

Uniprot

H9JJB7   I4DMZ3   A0A0N1PK10   A0A2H1VMM4   A0A194QB61   A0A212FBX7   + More
A0A2A4JSC2   A0A0K8SQV7   A0A0A9YND4   A0A1B6CDT7   U5EZP0   A0A146MC23   A0A146KYD7   R4V2H8   Q17CT4   E0VIG9   A0A164VPI4   A0A2M3Z902   A0A2M4BXP0   A0A023EMJ3   A0A182HCP9   A0A0N8CUT5   A0A0P5U7S6   A0A0P5THI2   A0A0P5X4Y6   A0A182FKL7   K7IN38   A0A0P5C365   A0A2M3Z942   A0A0L7QVR3   A0A0P5KGD4   A0A2M3Z915   A0A232F9E0   A0A2M4AM83   A0A2M4ALE0   A0A2M4AI43   A0A2M4API4   A0A2M4AI24   A0A2M4ANY9   A0A0P6HBW2   A0A2R7W824   W5JAW9   A0A1Q3F9Q8   A0A2M4BXM3   A0A1Y1N326   A0A2M4BXN8   A0A0P5BPD2   A0A088AGJ6   A0A0P6AL19   A0A310SCQ6   A0A067RL06   B0WL57   B4HQK8   B4KMJ8   A0A224XWW6   A0A0P4VMI1   T1HP54   A0A2A3EIW0   A0A0C9QRM5   B6IDM7   P48604   B4QEF7   V9IGZ1   B4P4F7   W8B6J8   B3NRJ1   A0A0V0G5J4   E9FXR3   A0A154PFD7   A0A034VZK2   A0A0K8TNL8   A0A0K8VKQ3   A0A182YB19   A0A0J7KRP3   A0A023F901   A0A026WE19   A0A3L8E276   B4MCN0   D6WBZ8   A0A195CXI8   A0A0N0U7N1   B4JVP2   A0A151JCI4   B3MHC4   A0A182N2A8   J3JWN2   A0A182J0D2   A0A1B0D6T2   A0A1W4VGQ8   A0A182X5N0   E2AKF8   B4MS96   A0A182K267   E9IZB2   A0A195AUE3   A0A158P0T5   Q28ZS1   Q7QHE2   A0A182HWB8  

Pubmed

19121390    22651552    26354079    22118469    25401762    26823975    + More
17510324    20566863    24945155    26483478    20075255    28648823    20920257    23761445    28004739    24845553    17994087    27129103    10731132    12537572    12537569    22936249    17550304    24495485    21292972    25348373    26369729    25244985    25474469    24508170    30249741    18362917    19820115    22516182    23537049    20798317    21282665    21347285    15632085    12364791   

EMBL

BABH01036417    AK402661    BAM19283.1    LADJ01051845    KPJ21509.1    ODYU01003372    + More
SOQ42046.1    KQ459249    KPJ02230.1    AGBW02009261    OWR51235.1    NWSH01000762    PCG74363.1    GBRD01010228    JAG55596.1    GBHO01012559    JAG31045.1    GEDC01025684    JAS11614.1    GANO01000431    JAB59440.1    GDHC01001640    JAQ16989.1    GDHC01018592    JAQ00037.1    KC741113    AGM32937.1    CH477304    EAT44188.1    DS235199    EEB13175.1    LRGB01001361    KZS12524.1    GGFM01004252    MBW25003.1    GGFJ01008688    MBW57829.1    GAPW01004054    JAC09544.1    JXUM01033610    KQ560995    KXJ80092.1    GDIP01096767    JAM06948.1    GDIP01116913    JAL86801.1    GDIP01126164    JAL77550.1    GDIP01077417    JAM26298.1    GDIP01180356    JAJ43046.1    GGFM01004293    MBW25044.1    KQ414726    KOC62631.1    GDIQ01184581    GDIQ01184580    JAK67144.1    GGFM01004276    MBW25027.1    NNAY01000599    OXU27471.1    GGFK01008569    MBW41890.1    GGFK01008282    MBW41603.1    GGFK01007123    MBW40444.1    GGFK01009346    MBW42667.1    GGFK01007103    MBW40424.1    GGFK01009178    MBW42499.1    GDIQ01021917    JAN72820.1    KK854300    PTY14355.1    ADMH02001908    ETN60553.1    GFDL01010796    JAV24249.1    GGFJ01008686    MBW57827.1    GEZM01013860    JAV92283.1    GGFJ01008689    MBW57830.1    GDIP01182104    JAJ41298.1    GDIP01027816    JAM75899.1    KQ777390    OAD52097.1    KK852563    KDR21285.1    DS231980    EDS30230.1    CH480816    EDW47743.1    CH933808    EDW10845.2    GFTR01003897    JAW12529.1    GDKW01000844    JAI55751.1    ACPB03001795    KZ288235    PBC31414.1    GBYB01003282    JAG73049.1    BT050467    ACJ13174.1    U34903    AE013599    AY094889    CM000362    CM002911    EDX06947.1    KMY93539.1    JR047325    AEY60378.1    CM000158    EDW90596.1    GAMC01009745    JAB96810.1    CH954179    EDV56143.1    GECL01002863    JAP03261.1    GL732526    EFX88242.1    KQ434892    KZC10527.1    GAKP01011098    JAC47854.1    GDAI01001616    JAI15987.1    GDHF01013174    JAI39140.1    LBMM01003943    KMQ92966.1    GBBI01001273    JAC17439.1    KK107260    EZA54163.1    QOIP01000001    RLU26622.1    CH940659    EDW71418.2    KQ971309    EEZ99113.1    KQ977141    KYN05380.1    KQ435706    KOX80228.1    CH916375    EDV98510.1    KQ979038    KYN23464.1    CH902619    EDV37924.1    BT127650    KB632375    AEE62612.1    ERL94032.1    AJVK01026253    GL440262    EFN66100.1    CH963850    EDW74985.2    GL767121    EFZ14048.1    KQ976738    KYM75677.1    ADTU01005782    ADTU01005783    CM000071    EAL25542.1    AAAB01008816    EAA05028.4    APCN01001484   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000218220    UP000008820    + More
UP000009046    UP000076858    UP000069940    UP000249989    UP000069272    UP000002358    UP000053825    UP000215335    UP000000673    UP000005203    UP000027135    UP000002320    UP000001292    UP000009192    UP000015103    UP000242457    UP000000803    UP000000304    UP000002282    UP000008711    UP000000305    UP000076502    UP000076408    UP000036403    UP000053097    UP000279307    UP000008792    UP000007266    UP000078542    UP000053105    UP000001070    UP000078492    UP000007801    UP000075884    UP000030742    UP000075880    UP000092462    UP000192221    UP000076407    UP000000311    UP000007798    UP000075881    UP000078540    UP000005205    UP000001819    UP000007062    UP000075840   

PRIDE

H9JJB7    B6IDM7    P48604   

Pfam

PF01025   GrpE

Interpro

IPR009012   GrpE_head        + More
IPR000740   GrpE       
IPR013805   GrpE_coiled_coil       

SUPFAM

SSF51064   SSF51064        + More
SSF58014   SSF58014       

Gene 3D

2.30.22.10     3.90.20.20    

CDD

cd00446  GrpE

ProteinModelPortal

H9JJB7   I4DMZ3   A0A0N1PK10   A0A2H1VMM4   A0A194QB61   A0A212FBX7   + More
A0A2A4JSC2   A0A0K8SQV7   A0A0A9YND4   A0A1B6CDT7   U5EZP0   A0A146MC23   A0A146KYD7   R4V2H8   Q17CT4   E0VIG9   A0A164VPI4   A0A2M3Z902   A0A2M4BXP0   A0A023EMJ3   A0A182HCP9   A0A0N8CUT5   A0A0P5U7S6   A0A0P5THI2   A0A0P5X4Y6   A0A182FKL7   K7IN38   A0A0P5C365   A0A2M3Z942   A0A0L7QVR3   A0A0P5KGD4   A0A2M3Z915   A0A232F9E0   A0A2M4AM83   A0A2M4ALE0   A0A2M4AI43   A0A2M4API4   A0A2M4AI24   A0A2M4ANY9   A0A0P6HBW2   A0A2R7W824   W5JAW9   A0A1Q3F9Q8   A0A2M4BXM3   A0A1Y1N326   A0A2M4BXN8   A0A0P5BPD2   A0A088AGJ6   A0A0P6AL19   A0A310SCQ6   A0A067RL06   B0WL57   B4HQK8   B4KMJ8   A0A224XWW6   A0A0P4VMI1   T1HP54   A0A2A3EIW0   A0A0C9QRM5   B6IDM7   P48604   B4QEF7   V9IGZ1   B4P4F7   W8B6J8   B3NRJ1   A0A0V0G5J4   E9FXR3   A0A154PFD7   A0A034VZK2   A0A0K8TNL8   A0A0K8VKQ3   A0A182YB19   A0A0J7KRP3   A0A023F901   A0A026WE19   A0A3L8E276   B4MCN0   D6WBZ8   A0A195CXI8   A0A0N0U7N1   B4JVP2   A0A151JCI4   B3MHC4   A0A182N2A8   J3JWN2   A0A182J0D2   A0A1B0D6T2   A0A1W4VGQ8   A0A182X5N0   E2AKF8   B4MS96   A0A182K267   E9IZB2   A0A195AUE3   A0A158P0T5   Q28ZS1   Q7QHE2   A0A182HWB8  

PDB

4ANI     E-value=4.64311e-13,     Score=177

KEGG

101745958    K03687 molecular chaperone GrpE | (RefSeq) grpE protein homolog, mitochondrial

GO

GO:0051087   GO:0005759   GO:0042803   GO:0006457   GO:0000774   GO:0016021   GO:0016853   GO:0005739   GO:0006626   GO:0051082   GO:0001405   GO:0030150   GO:0005634   GO:0006303   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR21237  

Subcellular location

Mitochondrion matrix  

Length:

220

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00016

Exp number, first 60 AAs:

0.00016

Total prob of N-in:

0.08799

outside

1  -  220

 

 

Pi

219.350953

Theta

187.543097

Tajima's D

1.006773

CLR

0.000316

CSRT

0.661866906654667

Interpretation

Uncertain