Gene

KWMTBOMO14671  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009610

Annotation

serine_protease_HP21_precursor_[Bombyx_mori]

Location

Bomo_Chr24(+):12340682-12357488      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 4.344

CDS

ATGGATCAATCAATATATTTGTTGTTAATGCTAGTGTTATTTGTGTGTGTTCATTGCGAATTCGAGGGTGAAGAATGTAAAAAAGGTAATTTATTAGGAGTCTGTACGAATATAAGGAAATGTCAGTCCGCGCTGAACGACATCAGAAACAGGAAATCACCACAGATTTGTTCGTTCGACAACGCGGATCCTGTTGTGTGCTGCTTTGATAACTCGATCAGTTCACGGGCTCCCCTCGCCACAACAACGCGTCGTACGCCGAGTTCTACCACAACGGAGTACGTACCACCCTCCTATGATTACCAGTCCAACAATGGCGACAAGAAATGCGAGGATGTACCGGCGGATCTGACGTCTCCCAAGACCGGGCAGAAGGCGTGGGACAAATGTATTGAATATCAAGAGCAGCTCGTGTATCCGTGTGAAAAGGGCGTCGCGCTCACCGGGGAGATCAGCCGCAGTAAGCACTGCCACCACGACGCGGACGAGCTCATCATTGGCGGCACCGATGCAGGCGTCAACGAATATCCGCACATGGTCCTGCTCGGCTACGGTGACGATGTCGCGAACATCCAGTGGCTGTGCGGGGGGGTGCTCATCAGTGAGCGCTTCGTGCTCACAGCCGGACACTGCCTATCCAGTAGAGAGGTTGGCGCAGTCAGATACGTGTATATCGGAGCCCTCGCCCGGCACGAGACCACGAACCCGTCCCGCCGCTACGCAGTCATCCGCGCTCACAGACACCCCGACTACAAGCCGCCTAGCAAGTATAACGACATCGCGCTGTTAGAGCTAGATCGACAGGTCCCGCTGGACCAGTACACAGTCCCGGCGTGTCTGCACACGGGAGACGCCGTCAATGACGAGCGGGCCTCCGCCACCGGCTGGGGACTCACCGAGAACCGGGGCTCCACGTCGGACGTGCTGCAGAAGGTGGTACTAACTAAGTTCACGTCGACGGAATGCTCCGAGAAGTACCCGACCAATCGCAACATGAAGCGCGGGTTCGACCCTCGGACTCAGATGTGCTACGGAGACAGGACATTGTCCAGAGACACTTGTCAGGGCGATAGCGGAGGTCCTATACAGATAAAAAGCAAGAAGATGGACTGTATGTACGTCGTGATAGGCGTGACGTCGTTTGGTCGGGCCTGTGGTTACGCGGGCGAGCCCGGGATCTACACCAGGGTCAGCCACTACGTACCCTGGATAGAGAGTGTCGTCTGGCCTTAG

Protein

MDQSIYLLLMLVLFVCVHCEFEGEECKKGNLLGVCTNIRKCQSALNDIRNRKSPQICSFDNADPVVCCFDNSISSRAPLATTTRRTPSSTTTEYVPPSYDYQSNNGDKKCEDVPADLTSPKTGQKAWDKCIEYQEQLVYPCEKGVALTGEISRSKHCHHDADELIIGGTDAGVNEYPHMVLLGYGDDVANIQWLCGGVLISERFVLTAGHCLSSREVGAVRYVYIGALARHETTNPSRRYAVIRAHRHPDYKPPSKYNDIALLELDRQVPLDQYTVPACLHTGDAVNDERASATGWGLTENRGSTSDVLQKVVLTKFTSTECSEKYPTNRNMKRGFDPRTQMCYGDRTLSRDTCQGDSGGPIQIKSKKMDCMYVVIGVTSFGRACGYAGEPGIYTRVSHYVPWIESVVWP

Similarity

Belongs to the peptidase S1 family.
Belongs to the PI3/PI4-kinase family.

Uniprot

F5BZV1   H9JJA9   Q5MPB3   A0A0N1PHF7   S4NXP2   A0A2A4K236   + More
A0A2H1VS51   Q5MPB2   A0A3S2NPZ4   A0A194Q9Z8   O44331   A0A194QB71   A0A346RAE0   Q5MPC1   A0A194Q9Q9   A0A212F6Q1   A0A0N0PDL6   A0A2W1B2N2   A0A2W1B0L2   A0A2H1VJ99   A0A2A4K2L1   A0A2W1B9D9   A0A0N1IHL2   A0A2A4K714   A0A2H1VFF0   Q5MPB6   A0A2W1BFG9   A0A212F107   A0A2W1BHZ8   A0A2W1AYZ6   A0A2A4JLI0   A0A2A4JMC3   A0A2H1VJG7   A0A2H1V6L6   A0A2A4J7N6   A0A2H1W424   A0A2W1B9E2   U5ESE3   A0A2W1BD72   H9JLA5   A0A2A4IWJ7   A0A2A4J4P7   A0A2H1VSY3   A0A2H1VTL8   B0W1A9   A0A1Q3FNX1   A0A2W1BGC1   A0A2A4KAM6   Q16NE9   A0A2J7Q4L6   A0A336LYA5   D6WCU1   A0A2H1VRC0   A0A182XUQ8   A0A1Y1KAU3   A0A182IIN2   A0A182VNZ6   Q5TNC5   A0A182THH3   A0A1Y1KPC1   B1B5K0   A0A182KNG1   A0A182Y982   A0A1B6GBU6   A0A2W1BCP3   A0A224XHV2   A0A1B6LG03   A0A067RHT4   A0A1B6L129   A0A182S507   A0A084VYF5   A0A182JES5   A0A1B6LJF7   A0A182NZ25   A0A2A4J0N6   A0A1B6DI71   A0A182FZY7   A0A0U4B511   W5JRY9   A0A1L8DQW0   A0A182WR24   A0A182Q673   A0A2W1B5J0   A0A1B0CS99   A0A182MQJ3   V5GMH2   A0A2H8TED5   A0A2H8TTU6  

Pubmed

19121390    15944088    26354079    23622113    9927173    29910977    + More
22118469    28756777    17510324    18362917    19820115    28004739    12364791    18195005    20966253    25244985    24845553    24438588    26694822    20920257    23761445   

EMBL

JF431073    AEB21638.1    BABH01036383    BABH01036384    BABH01036385    BABH01036386    + More
BABH01036387    BABH01036388    BABH01036389    BABH01036390    BABH01036391    AY672797    AAV91019.1    KQ460127    KPJ17583.1    GAIX01012077    JAA80483.1    NWSH01000257    PCG77964.1    ODYU01004095    SOQ43606.1    AY672798    AAV91020.1    RSAL01000491    RVE41548.1    KQ459249    KPJ02244.1    AF017664    AAB94558.1    KPJ02240.1    MH200930    AXS59140.1    AY672789    AAV91011.1    KPJ02243.1    AGBW02009991    OWR49389.1    KQ460130    KPJ17530.1    KZ150408    PZC70992.1    KZ150503    PZC70659.1    ODYU01002875    SOQ40903.1    NWSH01000265    PCG77882.1    KZ150484    PZC70714.1    KPJ17576.1    NWSH01000060    PCG80065.1    ODYU01002282    SOQ39557.1    AY672794    AAV91016.1    KZ150189    PZC72424.1    AGBW02010978    OWR47436.1    KZ150344    PZC71293.1    KZ150652    PZC70412.1    NWSH01001045    PCG72935.1    PCG72936.1    ODYU01002903    SOQ40975.1    ODYU01000940    SOQ36457.1    NWSH01002560    PCG67981.1    ODYU01006166    SOQ47783.1    KZ150324    PZC71401.1    GANO01003282    JAB56589.1    PZC71287.1    BABH01038780    NWSH01005248    PCG64337.1    NWSH01003268    PCG66648.1    ODYU01004086    SOQ43592.1    SOQ43594.1    DS231821    EDS44979.1    GFDL01005857    JAV29188.1    KZ150249    PZC71840.1    NWSH01000008    PCG80964.1    CH477825    EAT35883.2    NEVH01018378    PNF23527.1    UFQT01000075    UFQT01000299    SSX19399.1    SSX22964.1    KQ971311    EEZ99357.2    ODYU01003947    SOQ43326.1    GEZM01092351    JAV56586.1    APCN01003350    AAAB01008984    EAL38946.3    GEZM01077598    JAV63253.1    AB363979    BAG14261.1    GECZ01009869    JAS59900.1    KZ150278    PZC71645.1    GFTR01005802    JAW10624.1    GEBQ01017356    JAT22621.1    KK852672    KDR18777.1    GEBQ01022601    JAT17376.1    ATLV01018364    KE525231    KFB42999.1    GEBQ01016151    JAT23826.1    NWSH01004041    PCG65541.1    GEDC01011978    JAS25320.1    KU218697    ALX00077.1    ADMH02000599    ETN65690.1    GFDF01005349    JAV08735.1    AXCN02000734    PZC70661.1    AJWK01025808    AJWK01025809    AXCM01000044    GALX01005659    JAB62807.1    GFXV01000630    MBW12435.1    GFXV01005197    MBW17002.1   

Proteomes

UP000005204    UP000053240    UP000218220    UP000283053    UP000053268    UP000007151    + More
UP000002320    UP000008820    UP000235965    UP000007266    UP000076407    UP000075840    UP000075903    UP000007062    UP000075902    UP000075882    UP000076408    UP000027135    UP000075900    UP000030765    UP000075880    UP000075884    UP000069272    UP000000673    UP000075920    UP000075886    UP000092461    UP000075883   

PRIDE

F5BZV1    H9JJA9    H9JLA5   

Pfam

PF00089   Trypsin        + More
PF00454   PI3_PI4_kinase

Interpro

IPR033116   TRYPSIN_SER        + More
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       
IPR038565   CLIP_sf       
IPR022700   CLIP       
IPR000403   PI3/4_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR036940   PI3/4_kinase_cat_sf       

SUPFAM

SSF50494   SSF50494        + More
SSF56112   SSF56112       

Gene 3D

2.20.20.90     1.10.1070.11    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

F5BZV1   H9JJA9   Q5MPB3   A0A0N1PHF7   S4NXP2   A0A2A4K236   + More
A0A2H1VS51   Q5MPB2   A0A3S2NPZ4   A0A194Q9Z8   O44331   A0A194QB71   A0A346RAE0   Q5MPC1   A0A194Q9Q9   A0A212F6Q1   A0A0N0PDL6   A0A2W1B2N2   A0A2W1B0L2   A0A2H1VJ99   A0A2A4K2L1   A0A2W1B9D9   A0A0N1IHL2   A0A2A4K714   A0A2H1VFF0   Q5MPB6   A0A2W1BFG9   A0A212F107   A0A2W1BHZ8   A0A2W1AYZ6   A0A2A4JLI0   A0A2A4JMC3   A0A2H1VJG7   A0A2H1V6L6   A0A2A4J7N6   A0A2H1W424   A0A2W1B9E2   U5ESE3   A0A2W1BD72   H9JLA5   A0A2A4IWJ7   A0A2A4J4P7   A0A2H1VSY3   A0A2H1VTL8   B0W1A9   A0A1Q3FNX1   A0A2W1BGC1   A0A2A4KAM6   Q16NE9   A0A2J7Q4L6   A0A336LYA5   D6WCU1   A0A2H1VRC0   A0A182XUQ8   A0A1Y1KAU3   A0A182IIN2   A0A182VNZ6   Q5TNC5   A0A182THH3   A0A1Y1KPC1   B1B5K0   A0A182KNG1   A0A182Y982   A0A1B6GBU6   A0A2W1BCP3   A0A224XHV2   A0A1B6LG03   A0A067RHT4   A0A1B6L129   A0A182S507   A0A084VYF5   A0A182JES5   A0A1B6LJF7   A0A182NZ25   A0A2A4J0N6   A0A1B6DI71   A0A182FZY7   A0A0U4B511   W5JRY9   A0A1L8DQW0   A0A182WR24   A0A182Q673   A0A2W1B5J0   A0A1B0CS99   A0A182MQJ3   V5GMH2   A0A2H8TED5   A0A2H8TTU6  

PDB

2OLG     E-value=3.43986e-30,     Score=328

KEGG

100862834    no KO assigned | (RefSeq) serine protease HP21

GO

GO:0004252   GO:0008236   GO:0016301   GO:0016021   GO:0006508   GO:0003824   GO:0008081   GO:0005234   GO:0008152   GO:0016491   GO:0015930  

SignalP

Position:   1 - 19,         Likelihood:  0.998261

 

 

Length:

410

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.417810000000001

Exp number, first 60 AAs:

0.33347

Total prob of N-in:

0.01874

outside

1  -  410

 

 

Pi

255.897749

Theta

158.088883

Tajima's D

3.303905

CLR

0.114536

CSRT

0.989200539973001

Interpretation

Uncertain