Gene

KWMTBOMO14660

Annotation

crustacean_cardioactive_peptide_precursor_[Bombyx_mori]

Location

Bomo_Chr24(+):12184682-12187517      View in EpiBrowser

Full name

Cardioactive peptide      

Alternative Name

Cardioacceleratory peptide 2a
Crustacean cardioactive peptide

Location in the cell

Extracellular   Reliability : 3.54

CDS

ATGACGTCGCGCGTTTTGTTAGTGCTTGTGGTCGCTCTACTGTGCGCCGAGTGTTGCGTGACGGCCACGATCCCGAGGAACTTTGATCCGAGATCGAACGAGGAGATGGTGACGATGCCAAAGAAGAGACCCTTCTGCAACGCTTTCACTGGATGCGGCAGGAAGCGTTCCCAGACTGCTCCCGGAATGCCAAACCAGGACCTGATGCGCCAAAGACAGTACGTCGACGAAGACACTCTAGGCACAATGCTCGACTCGGAATCGGCCATAGACGAACTATCCCGCCAAATTCTATCCGAAGCGAAACTGTGGGAAGCCATACAGGAGGCCAGCGCTGAAATAGCGAGACGGAAACAAAAAGAATTCTATAATTCACAATAA

Protein

MTSRVLLVLVVALLCAECCVTATIPRNFDPRSNEEMVTMPKKRPFCNAFTGCGRKRSQTAPGMPNQDLMRQRQYVDEDTLGTMLDSESAIDELSRQILSEAKLWEAIQEASAEIARRKQKEFYNSQ

Description

Cardioregulatory neurohormone that increases heart beat rate during adult wing inflation; has no effect on beat amplitude. The effect of CCAP is both ino- and chronotropic.
Cardioregulatory neurohormone that increases heart beat rate during adult wing inflation; has no effect on beat amplitude. The effect of CCAP is both ino- and chronotropic (By similarity).

Keywords

3D-structure   Amidation   Cleavage on pair of basic residues   Direct protein sequencing   Disulfide bond   Hormone   Neuropeptide   Secreted   Signal   Complete proteome   Reference proteome  

Feature

peptide  Cardioactive peptide

Uniprot

B3IUE1   H9JJA5   A0A2A4K9C9   A0A385H8U6   M4QC41   A0A0S1U097   + More
Q8WRC7   A0A0N0PE17   A0A194QFJ6   A0A212F112   A0A0C5B7N2   J9PTF0   A0A2H1WGE4   A0A2H1V4Q9   I6LLP8   D6WA20   A0A1B0CFK9   A0A2J7QSL2   Q17NP9   A0A1B6MCB7   A0A1B6I6M5   A0A1B6JQY1   N6U4D1   U3U430   A0A182H5Z6   A0A345BED7   A0A1B6GJ26   A0A2P8ZEP6   A0A3Q8S5Q4   A0A067QIJ7   A0A1E1G7R6   A0A1J1IRF9   E3VW01   D2J4U0   B0XKC5   F1AHD5   B0WGM9   A0A2S2QM63   A0A0L0CD54   C4WWN1   X1WNB0   A0A182NBP6   A0A182WGH1   A0A084WU59   A0A182QLF9   A0A182Y0M1   A0A182VMQ7   A0A182UAW5   A0A182XN70   Q7PM76   A0A182HRZ1   A0A182K2Z9   A0A182R1L5   A0A182P5Q8   A0A182MRS0   A0A182IYU0   A0A2S2NZW5   A0A2H8TH14   A0A182SSM3   B4HES2   B4LXC8   B3LZU0   W5JS42   A0A182F0Z0   B4R0P9   A0A1B2AKX3   Q9VCW0   B3P8L0   B4KAC6   B4JIE3   B4PMD9   A0A1W4VMH6   B4N9R1   A0A1I8PMM4   Q29AT4   B4G5V3   A0A1A9ZHN0   A0A1A9VB99   A0A1B0G7Y1   A0A1B0BNM5   A0A1A9XG96   A0A1A9WJB0  

Pubmed

19121390    30171635    28756777    11683436    1426284    3925062    + More
14706524    26354079    22118469    25640113    18362917    19820115    17510324    23537049    23932938    26483478    29403074    30467353    24845553    20624439    26108605    24438588    25244985    12364791    14747013    17210077    23364571    17994087    20920257    23761445    10731132    12537572    15242619    17550304    15632085   

EMBL

AB298937    BAG50376.1    BABH01036360    NWSH01000015    PCG80817.1    MH028078    + More
AXY04247.1    KC340920    KZ149901    AGH25552.1    PZC78547.1    KT005962    ALM30313.1    AF451838    AF071800    AAC24871.1    AAL39064.1    KQ460127    KPJ17578.1    KQ459249    KPJ02241.1    AGBW02010978    OWR47435.1    KJ801914    AJM76783.1    JN595810    AEZ02304.1    ODYU01008496    SOQ52148.1    ODYU01000640    SOQ35756.1    HM622134    ADM26614.1    KQ971312    EEZ99275.1    AJWK01010159    AJWK01010160    NEVH01011876    PNF31581.1    CH477197    EAT48354.1    GEBQ01006409    JAT33568.1    GECU01025118    JAS82588.1    GECU01006151    JAT01556.1    APGK01050006    KB741164    KB632258    ENN73447.1    ERL90812.1    AB817249    BAO00946.1    JXUM01113107    KQ565657    KXJ70811.1    MF765469    AXF48189.1    GECZ01007352    JAS62417.1    PYGN01000078    PSN54967.1    MH311628    AZK31338.1    KK853313    KDR08645.1    LC146498    BAV78802.1    CVRI01000058    CRL02744.1    HQ264139    ADO87033.1    GQ888668    ACZ52615.1    DS233791    EDS31570.1    ACPB03016273    ACPB03016274    GU724510    ADK73625.1    DS231927    EDS27058.1    GGMS01009642    MBY78845.1    JRES01000563    KNC30171.1    AK342166    BAH72301.1    ABLF02034230    ABLF02034232    ABLF02058788    ATLV01027002    KE525421    KFB53753.1    AXCN02000684    JX880074    AAAB01008980    AGG10332.1    EAA14174.4    APCN01001777    AXCM01001833    GGMR01009983    MBY22602.1    GFXV01000763    MBW12568.1    CH480815    EDW43233.1    CH940650    EDW67806.2    CH902617    EDV43084.1    ADMH02000623    ETN65569.1    CM000364    EDX13972.1    KX532005    ANY27815.1    AE014297    BT024429    AAF56045.2    CH954182    EDV54105.1    CH933806    EDW14613.1    CH916369    EDV93024.1    CM000160    EDW98044.1    CH964232    EDW80626.1    CM000070    EAL27265.2    CH479179    EDW23746.1    CCAG010010575    JXJN01017478   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000007266    + More
UP000092461    UP000235965    UP000008820    UP000019118    UP000030742    UP000069940    UP000249989    UP000245037    UP000027135    UP000183832    UP000002320    UP000015103    UP000037069    UP000007819    UP000075884    UP000075920    UP000030765    UP000075886    UP000076408    UP000075903    UP000075902    UP000076407    UP000007062    UP000075840    UP000075881    UP000075900    UP000075885    UP000075883    UP000075880    UP000075901    UP000001292    UP000008792    UP000007801    UP000000673    UP000069272    UP000000304    UP000000803    UP000008711    UP000009192    UP000001070    UP000002282    UP000192221    UP000007798    UP000095300    UP000001819    UP000008744    UP000092445    UP000078200    UP000092444    UP000092460    UP000092443    UP000091820   

PRIDE

B3IUE1    H9JJA5    Q9VCW0   

Pfam

PF11105   CCAP

Interpro

IPR024276   CCAP        + More
IPR009003   Peptidase_S1_PA       

SUPFAM

SSF50494   SSF50494       

ProteinModelPortal

B3IUE1   H9JJA5   A0A2A4K9C9   A0A385H8U6   M4QC41   A0A0S1U097   + More
Q8WRC7   A0A0N0PE17   A0A194QFJ6   A0A212F112   A0A0C5B7N2   J9PTF0   A0A2H1WGE4   A0A2H1V4Q9   I6LLP8   D6WA20   A0A1B0CFK9   A0A2J7QSL2   Q17NP9   A0A1B6MCB7   A0A1B6I6M5   A0A1B6JQY1   N6U4D1   U3U430   A0A182H5Z6   A0A345BED7   A0A1B6GJ26   A0A2P8ZEP6   A0A3Q8S5Q4   A0A067QIJ7   A0A1E1G7R6   A0A1J1IRF9   E3VW01   D2J4U0   B0XKC5   F1AHD5   B0WGM9   A0A2S2QM63   A0A0L0CD54   C4WWN1   X1WNB0   A0A182NBP6   A0A182WGH1   A0A084WU59   A0A182QLF9   A0A182Y0M1   A0A182VMQ7   A0A182UAW5   A0A182XN70   Q7PM76   A0A182HRZ1   A0A182K2Z9   A0A182R1L5   A0A182P5Q8   A0A182MRS0   A0A182IYU0   A0A2S2NZW5   A0A2H8TH14   A0A182SSM3   B4HES2   B4LXC8   B3LZU0   W5JS42   A0A182F0Z0   B4R0P9   A0A1B2AKX3   Q9VCW0   B3P8L0   B4KAC6   B4JIE3   B4PMD9   A0A1W4VMH6   B4N9R1   A0A1I8PMM4   Q29AT4   B4G5V3   A0A1A9ZHN0   A0A1A9VB99   A0A1B0G7Y1   A0A1B0BNM5   A0A1A9XG96   A0A1A9WJB0  

KEGG

100174843    no KO assigned | (RefSeq) CCAP; crustacean cardioactive peptide

GO

GO:0007218   GO:0005576   GO:0005184   GO:0045823   GO:0016021   GO:0071855   GO:0005615   GO:0010460  

Subcellular location

Secreted  

SignalP

Position:   1 - 22,         Likelihood:  0.997920

 

 

Length:

126

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

17.41777

Exp number, first 60 AAs:

17.41777

Total prob of N-in:

0.80485

POSSIBLE N-term signal

sequence

inside

1  -  4

TMhelix

5  -  24

outside

25  -  126

 

 

Pi

185.660274

Theta

147.206683

Tajima's D

0.882789

CLR

0.626724

CSRT

0.629918504074796

Interpretation

Uncertain