Gene

KWMTBOMO14648

Pre Gene Modal

BGIBMGA009599

Annotation

PREDICTED:_uncharacterized_protein_LOC106115983_[Papilio_xuthus]

Location

Bomo_Chr24(+):11891359-11914583      View in EpiBrowser

Full name

Dihydroorotate dehydrogenase (quinone), mitochondrial      

Location in the cell

PlasmaMembrane   Reliability : 2.656

CDS

ATGTTTATAAAACTCGCGCTAATATTGACTGCGACGGTCGCATCAGCGCACGCCAGTGTCCAGCTCCTATTCCCGGAACCCAACAGGCAGTATATATATTTCATTAAAGCGAATGTCTCGAGCACCACCCTGGCACCGAAACGCAGCGGCTCCTACTGGACCTTAGAAGGAAAGCTTTACGTTAGGGCTTTCGATAACTTCACCAGATTAAGGCTTCAGCTGAGCGATCTGAAGAAATCAGTTTCCGGTTACAACAATATAATTACAGAAGACAGCTACATAAAAGAGCCATGGGATTTGGATTATATGGAAGGAGGCTTGATTAAGACAATCTCTGTTGGACAAGAGCCTGTATGGTGTACAAACTTGAAGAGAGCACTTTCCGTAAATTTTCAATTGAAAAAGGGCAAAGGAACGTATTACAGGGATGAGCCTTGCCTTGACAGCGTCTGCATGATGATATACACGCCAAAAGGAAACAAAATCCAGAAGTTCACCAGCTATCGGCTCCCAACGACCAAGAGCTCCAGGTCCTGGTCGTCCCTGTCTGGTGACTACTCGGGAAAACCCAGCGTGGACACAATCAACACAGCGGAGAGGCTGTATGTGGTCGATGACCGTAAAGGACTACTCAGCTTGGACCTGCAAGGGTCATATGAATTTAGGACGCACGACCACATTCTGGCCGTAAACTCTGAGCTATCGATCAACTACGACAACGATATACCGGGGAAATCAGTGGAGAAATTGAACCTAACCGAATATACCGTCACTTATGTGGCCACAGATTTTTGCGATCCGACCAACGGAATCAGAAACGTCACGCAGAGTTTCCTGAAGAATCACACTCAAGAGCTACTCCTGAAAATAGCAAGAGGCATTGACGCAGATAATATAGTCAGGGACCCGTCATTGATACACAATTTGGACTTTATCGAGTTGTTGAACACTATAGCCCAGCTGAACTACACGACCATCATTAAACTGTTCGAAGACCTGGTCCTAGGCACCAGTTACGACATGGAGACATCCAGGAATATCTTCCTGGAGGCGCTCCCTCATGCCAGGAGCGAGGCCTGCGCTAGGTTCATCAAGTACCTGGTGATCGAAGAGAAGGATAAGATAGAAGATGCAGCTTTGCTCTCCCTCATCAGAAAGCTTCCATTCAACGTAGCCACCTTCGACCAGAGTTTGCTCGAAGAGCTGGAGGCCTTTACCAAGCTAGGCCCGGATTTTAGGGCGGAAATACGCCACGCCGGGATCTTGAGTTTCGCCAGCTTGCTGCATAAGACAATTGAATTTTCACTTATCAAACAGGACTACATTGACAATGTAGTCGTGAAATATTTCAGAATGTACAGTGATTGCCCTCAATACCTGGACAGGATGGTGTGGCTCCAGGGTCTGTGCAACATAGGCTATTCAGCCGAAGGCTACCTGCGGATCATTTATGCTGATAGTGGAAGGGACAGACACGAGAGGCTGTGGGCAGCCGTGGCAATCGACCCTAAGCACGAGGAGGCATTTAAGGTCCTGGAATCGACTCTATCGATACTGACCAATCAATCGGAGCACATTCAACTGAGGATAGCGTCGCTGCACATGTTCCTGACGTCACAGCAGATCAGAGAGAACGACTTTATATTCGTTCACAACTACATAAGCACGTGCAACAACAATCAATTGAAGAGGTTCTGGTATACGACCGTTAAGAACCTGATGACCAGCAAATCGTTCACTGACTACAGGGTCGCTTCTTACTACGTGCCGTTCATAGTCAATCAAGTATCCAACCCGGATCCGTTGTATCTCCTGACCAACAACTATATTATCAGCGGCGAAGAGGATGTCGGCTCTCCGTCGCTTCAGGTCATCAGCGTTGGGGACACCTTAGGAGTGATACCGCCATTTATTGCCGCGAAACTCAATACTGGAGGCAGGAGACCGTATAAAGTAGCCGTATATCTCATCATCGAAGGTGTAACAACAACCTTCTACAAAAAGGTCCTCAAGTCTCTATCGAGCACTCAAGTTCTCAATGTGGAGAAGCTGCTTCTAGTGCTAAAAAACATGAAAGCCTGGACGCTAAAGACTCCAGAGAAGGTTCACATTGACATTGTCATTAAAACCCACGATAAGACGATTTTCGCTACGCATTTAAATCAATCCAGGATTGACAGTGTCAACATACAGGATTTGGCGTACATTGAAGATTTCTTGCGGTTCGGCAGTCATATAAACCAGCAAATGGTATACTACCCTTTTCAATCAGACATTCATGTCCCGAGCGAATTAGGTACCCCAATAAGACTCCAATCGCTGATCGTGTCATTCACTTCAATCAGAGGTAATTTGACAGCTCCTTCCAGCAACGACATGACTTGGAGAAATGATTTGCACATCAGGTACCAAGGAACATCGGTGACTTCACTATCTACGGATGGTCCACTCATCCAAACAGCGCACAGGGCTAGAATCCAACAATCAATGGTCGCACATCTTCCTATGAAGTTCAATGTATCATTCTCAGGCTCTGATGGATCTCTGCAGTTGACCTGGCCGAACCCTATGTCCCAACAAGGTGGAGTGGCAATGCATTCAAGGGTACAGGTGGCTATGGAAAGTGTCTCAAAGAAGTATAATTATACAGTGACCGTTGGAGACAGCAGTAGCGGGGCTGTCAATCAAACCCGTGGAATATTCTTCGACTGCGATAGACCTGTGACTGATGCTGAGTTACTTAATCGCCTGTTAACATACAAGGATAACAATTACGAGTAA

Protein

MFIKLALILTATVASAHASVQLLFPEPNRQYIYFIKANVSSTTLAPKRSGSYWTLEGKLYVRAFDNFTRLRLQLSDLKKSVSGYNNIITEDSYIKEPWDLDYMEGGLIKTISVGQEPVWCTNLKRALSVNFQLKKGKGTYYRDEPCLDSVCMMIYTPKGNKIQKFTSYRLPTTKSSRSWSSLSGDYSGKPSVDTINTAERLYVVDDRKGLLSLDLQGSYEFRTHDHILAVNSELSINYDNDIPGKSVEKLNLTEYTVTYVATDFCDPTNGIRNVTQSFLKNHTQELLLKIARGIDADNIVRDPSLIHNLDFIELLNTIAQLNYTTIIKLFEDLVLGTSYDMETSRNIFLEALPHARSEACARFIKYLVIEEKDKIEDAALLSLIRKLPFNVATFDQSLLEELEAFTKLGPDFRAEIRHAGILSFASLLHKTIEFSLIKQDYIDNVVVKYFRMYSDCPQYLDRMVWLQGLCNIGYSAEGYLRIIYADSGRDRHERLWAAVAIDPKHEEAFKVLESTLSILTNQSEHIQLRIASLHMFLTSQQIRENDFIFVHNYISTCNNNQLKRFWYTTVKNLMTSKSFTDYRVASYYVPFIVNQVSNPDPLYLLTNNYIISGEEDVGSPSLQVISVGDTLGVIPPFIAAKLNTGGRRPYKVAVYLIIEGVTTTFYKKVLKSLSSTQVLNVEKLLLVLKNMKAWTLKTPEKVHIDIVIKTHDKTIFATHLNQSRIDSVNIQDLAYIEDFLRFGSHINQQMVYYPFQSDIHVPSELGTPIRLQSLIVSFTSIRGNLTAPSSNDMTWRNDLHIRYQGTSVTSLSTDGPLIQTAHRARIQQSMVAHLPMKFNVSFSGSDGSLQLTWPNPMSQQGGVAMHSRVQVAMESVSKKYNYTVTVGDSSSGAVNQTRGIFFDCDRPVTDAELLNRLLTYKDNNYE

Catalytic Activity

(S)-dihydroorotate + a quinone = a quinol + orotate

Cofactor

FMN

Similarity

Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

Uniprot

H9JJ98   A0A2A4K0R9   A0A2W1BBT1   A0A194QFK9   A0A026WPZ4   A0A3L8DYC9   + More
A0A034V3R1   A0A0K8UNE4   A0A0Q9WPU1   A0A0Q9WF51   B4LX83   A0A0Q9WEG1   A0A1B6CK15   F4WPC6   A0A1B0G6S5   A0A1A9UTM2   A0A1B0AAE9   B4K5R0   A0A0Q9X835   E9ISQ2   A0A1I8PKN4   A0A348G628   A0A1Q3G5A9   B4JT44   A0A0M3QXG4   A0A151WMD2   E2AYB4   A0A1I8MI26   T1PJ31   A0A336M8U2   A0A195E5R5   E2B933   B4NBA8   A0A182YQY9   A0A1W4VB40   A0A1W4VN36   A0A182Q101   A0A1Y9HE78   Q296Q3   B4GEU8   A0A158NR50   A0A1A9WJI7   A0A1Y9H224   A0A0L0CC61   A0A182IP16   A0A1B0EW00   B0W4C5   A0A3B0JV46   A0A0C9PNC8   A0A182VZ35   B4PRJ7   Q9VF24   B3P3W3   A0A1S4FCK4   A0A182GER8   A0A182TLT0   A0A195EV90   B4HLH2   A0A2C9GQ74   A0A182JX83   Q7PYN7   A0A182VEI7   A0A232F256   A0A182PRI3   J9KIR8   A0A182XB89   B3M385   A0A2J7QQ32   A0A2J7QQ26   A0A182FQR0   A0A154NWQ0   A0A2P1N020   A0A1J1ID62   L7XB27   A0A195B0H9   A0A2S2QLT4   A0A088AGY7   A0A2H4QUD8   A0A151IA69   K7JB44   A0A1B6H2A9   B4QXT7  

EC Number

1.3.5.2

Pubmed

19121390    28756777    26354079    24508170    30249741    25348373    + More
17994087    21719571    21282665    20798317    25315136    25244985    15632085    21347285    26108605    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    26483478    12364791    14747013    17210077    28648823    29226991    29143394    20075255   

EMBL

BABH01036321    BABH01036322    BABH01036323    BABH01036324    NWSH01000319    PCG77508.1    + More
KZ150246    PZC71871.1    KQ459249    KPJ02256.1    KK107139    EZA57751.1    QOIP01000003    RLU25125.1    GAKP01021803    JAC37149.1    GDHF01024203    GDHF01014085    JAI28111.1    JAI38229.1    CH940650    KRF82884.1    KRF82882.1    EDW66735.1    KRF82883.1    GEDC01023546    JAS13752.1    GL888243    EGI64021.1    CCAG010013864    CCAG010013865    CH933806    EDW15122.1    KRG01396.1    GL765434    EFZ16391.1    FX985567    BBF97901.1    GFDL01000061    JAV34984.1    CH916373    EDV94934.1    CP012526    ALC45883.1    KQ982944    KYQ48967.1    GL443864    EFN61573.1    KA648125    AFP62754.1    UFQT01000718    SSX26742.1    KQ979608    KYN20426.1    GL446425    EFN87799.1    CH964232    EDW81072.1    AXCN02000028    CM000070    EAL28405.2    CH479182    EDW34133.1    ADTU01023701    ADTU01023702    ADTU01023703    JRES01000623    KNC29817.1    AJWK01005179    AJWK01005180    DS231836    EDS33210.1    OUUW01000008    SPP84272.1    GBYB01002653    JAG72420.1    CM000160    EDW97397.1    AE014297    AY119475    AAF55237.2    AAM50129.1    CH954181    EDV49069.1    JXUM01058460    JXUM01058461    KQ562003    KXJ76939.1    KQ981965    KYN31804.1    CH480815    EDW41992.1    APCN01002042    AAAB01008987    EAA01220.5    NNAY01001262    OXU24573.1    ABLF02023890    ABLF02023893    CH902617    EDV43546.1    NEVH01012087    PNF30689.1    PNF30690.1    KQ434775    KZC04099.1    KY700850    AVP41182.1    CVRI01000047    CRK97682.1    JX974432    AGC97434.1    KQ976691    KYM77966.1    GGMS01009448    MBY78651.1    KY940305    ATY35166.1    KQ978233    KYM96068.1    AAZX01001765    GECZ01000968    JAS68801.1    CM000364    EDX12761.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053097    UP000279307    UP000008792    + More
UP000007755    UP000092444    UP000078200    UP000092445    UP000009192    UP000095300    UP000001070    UP000092553    UP000075809    UP000000311    UP000095301    UP000078492    UP000008237    UP000007798    UP000076408    UP000192221    UP000075886    UP000075900    UP000001819    UP000008744    UP000005205    UP000091820    UP000075884    UP000037069    UP000075880    UP000092461    UP000002320    UP000268350    UP000075920    UP000002282    UP000000803    UP000008711    UP000069940    UP000249989    UP000075902    UP000078541    UP000001292    UP000075840    UP000075881    UP000007062    UP000075903    UP000215335    UP000075885    UP000007819    UP000076407    UP000007801    UP000235965    UP000069272    UP000076502    UP000183832    UP000078540    UP000005203    UP000078542    UP000002358    UP000000304   

PRIDE

H9JJ98    Q9VF24   

Pfam

PF01347   Vitellogenin_N        + More
PF09172   DUF1943
PF00094   VWD
PF07842   GCFC
PF01180   DHO_dh
PF00400   WD40
PF00439   Bromodomain

Interpro

IPR011030   Lipovitellin_superhlx_dom        + More
IPR001747   Lipid_transpt_N       
IPR015819   Lipid_transp_b-sht_shell       
IPR015816   Vitellinogen_b-sht_N       
IPR015255   Vitellinogen_open_b-sht       
IPR001846   VWF_type-D       
IPR022783   GCFC_dom       
IPR012890   GCFC       
IPR005720   Dihydroorotate_DH       
IPR001295   Dihydroorotate_DH_CS       
IPR005719   Dihydroorotate_DH_2       
IPR013785   Aldolase_TIM       
IPR036427   Bromodomain-like_sf       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR018359   Bromodomain_CS       
IPR006594   LisH       
IPR017986   WD40_repeat_dom       
IPR001487   Bromodomain       
IPR001680   WD40_repeat       

SUPFAM

SSF48431   SSF48431        + More
SSF56968   SSF56968       
SSF50978   SSF50978       
SSF47370   SSF47370       

Gene 3D

1.25.10.20     2.30.230.10     3.20.20.70     1.20.920.10     2.130.10.10    

CDD

cd04738  DHOD_2_like

ProteinModelPortal

H9JJ98   A0A2A4K0R9   A0A2W1BBT1   A0A194QFK9   A0A026WPZ4   A0A3L8DYC9   + More
A0A034V3R1   A0A0K8UNE4   A0A0Q9WPU1   A0A0Q9WF51   B4LX83   A0A0Q9WEG1   A0A1B6CK15   F4WPC6   A0A1B0G6S5   A0A1A9UTM2   A0A1B0AAE9   B4K5R0   A0A0Q9X835   E9ISQ2   A0A1I8PKN4   A0A348G628   A0A1Q3G5A9   B4JT44   A0A0M3QXG4   A0A151WMD2   E2AYB4   A0A1I8MI26   T1PJ31   A0A336M8U2   A0A195E5R5   E2B933   B4NBA8   A0A182YQY9   A0A1W4VB40   A0A1W4VN36   A0A182Q101   A0A1Y9HE78   Q296Q3   B4GEU8   A0A158NR50   A0A1A9WJI7   A0A1Y9H224   A0A0L0CC61   A0A182IP16   A0A1B0EW00   B0W4C5   A0A3B0JV46   A0A0C9PNC8   A0A182VZ35   B4PRJ7   Q9VF24   B3P3W3   A0A1S4FCK4   A0A182GER8   A0A182TLT0   A0A195EV90   B4HLH2   A0A2C9GQ74   A0A182JX83   Q7PYN7   A0A182VEI7   A0A232F256   A0A182PRI3   J9KIR8   A0A182XB89   B3M385   A0A2J7QQ32   A0A2J7QQ26   A0A182FQR0   A0A154NWQ0   A0A2P1N020   A0A1J1ID62   L7XB27   A0A195B0H9   A0A2S2QLT4   A0A088AGY7   A0A2H4QUD8   A0A151IA69   K7JB44   A0A1B6H2A9   B4QXT7  

KEGG

101744175    no KO assigned | (RefSeq) uncharacterized LOC101744175

GO

GO:0005319   GO:0030513   GO:0005615   GO:0043395   GO:0007474   GO:0036122   GO:0003677   GO:0005634   GO:0003700   GO:0006207   GO:0044205   GO:0005743   GO:0004152   GO:0006869   GO:0006811   GO:0016020   GO:0004970   GO:0005234   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR12214  

Subcellular location

Mitochondrion inner membrane  

SignalP

Position:   1 - 18,         Likelihood:  0.983408

 

 

Length:

926

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.24617

Exp number, first 60 AAs:

2.24185

Total prob of N-in:

0.10894

outside

1  -  926

 

 

Pi

248.825919

Theta

177.718882

Tajima's D

1.638631

CLR

0.121014

CSRT

0.814859257037148

Interpretation

Uncertain