Gene

KWMTBOMO14612  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008778

Annotation

PREDICTED:_putative_U5_small_nuclear_ribonucleoprotein_200_kDa_helicase_[Bombyx_mori]

Location

Bomo_Chr24(-):11223811-11226993      View in EpiBrowser

Full name

Putative U5 small nuclear ribonucleoprotein 200 kDa helicase      

Alternative Name

Protein lethal (3) 72Ab

Location in the cell

Nuclear   Reliability : 2.873

CDS

ATGGCTGACGCGGCTGCCAGACAGCTGCAGTATGAGTACAAGGCCAACTCGAATCTTGTACTGCAAGCTGATGTAAGGTTAATAGAGAGACGTGGTCGAGATGAAGCGACCGGTGAAGTTTTGTCGCTGTCTGGAAAGCTCACAGGAACTAAGATGGGTGATCGAGCTCAACGCACTAAACCAGATAAAGCTGAGGAGAGAAAGGCTAAGCGTCAAAAACGTGATGAAGCCTCCTACGAACTCTCTAAATCAAAATCCAGTCGTGTGGCTTGGGCTGATGATGCTCCAGGCGTTCTATACCGTCCCAGAGCCCAACACACTAGACATACCTATGAACTACTGCTTGCGTTCATGCAGAGCTCTCTCGGAGACCAGCCAAGGGATATATTATGCGGCGCTTGTGATGAGGTACTCTTAGTTCTAAAGAACGATAAATTGAAAGATCCAGAGAAGAAGAAGGAAATTGAGATGCTCCTCGGTTCCATACCAGACGAGAGATTTGCTTTACTTGTCAATTTAGGCAAGAAAATAACAGACTTCAACATGACCACGGCAACAGAGAGCAACACCGAAATAGACGAGACATACGGCATCAATGTGCAGTTTGAAGAGTCCTCTGAGGAAGATGATGAAGATGCATATGGGGAGGTAAGAGAAGAAGATAAAGAAGATGGTGAAGGGTCAGAGAATGAGAAAGAAAAAGAATCCAGCGGAGAAGAGGACAGTGATACAGAGGGGAAGAGGAATGCCATTCACACTAATGATGAAGGATGA

Protein

MADAAARQLQYEYKANSNLVLQADVRLIERRGRDEATGEVLSLSGKLTGTKMGDRAQRTKPDKAEERKAKRQKRDEASYELSKSKSSRVAWADDAPGVLYRPRAQHTRHTYELLLAFMQSSLGDQPRDILCGACDEVLLVLKNDKLKDPEKKKEIEMLLGSIPDERFALLVNLGKKITDFNMTTATESNTEIDETYGINVQFEESSEEDDEDAYGEVREEDKEDGEGSENEKEKESSGEEDSDTEGKRNAIHTNDEG

Description

Putative RNA helicase involved in the second step of RNA splicing.

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Similarity

Belongs to the helicase family. SKI2 subfamily.

Keywords

ATP-binding   Complete proteome   Helicase   Hydrolase   mRNA processing   mRNA splicing   Nucleotide-binding   Nucleus   Reference proteome   Repeat   Spliceosome  

Feature

chain  Putative U5 small nuclear ribonucleoprotein 200 kDa helicase

Uniprot

H9JGY1   A0A2W1B6C9   A0A1E1WID6   A0A0N1PHB0   A0A212FM88   A0A2A4K8S5   + More
A0A194Q9U6   A0A1B6D867   A0A139WNM0   J9K3Y5   U4U3Y2   A0A2R7WJ62   A0A034V4U5   A0A1Y1MYR1   B4N718   B4ITW8   A0A0L0CI23   A0A088AQI7   A0A2A3EKY9   B3M9U8   Q9VUV9   A0A0J9RW02   B4QLR5   B3NDP3   A0A0L7QNR8   A0A1W4VP22   A0A182H940   A0A1B6M691   A0A1I8MTD7   A0A1W4WLT7   B4KYI7   A0A2P8YP35   B4J3P7   A0A146LVA0   A0A0K8UJE3   A0A1S4ESM1   A0A1A9ZDE9   A0A1B0FDY4   A0A1A9UPZ3   A0A1A9WKU3   B4LDY9   A0A1B0CJP7   W8BT97   A0A2J7RCH7   A0A0A1WFR4   A0A2J7RCH2   A0A1A9XFP2   A0A1Q3F5S4   B0X1D8   A0A1B6GEL8   T1HLL0   Q2M0I9   A0A3B0JVC3   A0A067RJY2   A0A0T6B4B5   A0A182TAI4   A0A232EQ00   K7JA29   E0VV24   A0A069DYD2   A0A1I8Q351   A0A0M4EMC3   T1JH32   A0A1J1J3B5   K1RGJ6   A0A195BGJ6   A0A151JZT6   A0A158NJE4   F4WS28   A0A195CCL5   A0A026W729   E2B7U8   E2A6Q4   A0A182YAH9   A0A182VWG1   V3ZP59   A0A182MTI2   A0A151X4T3   A0A2R2MMN6   A0A182IVX8   A0A2D0QYR1   A0A182JU03   A0A182L9F5   A0A182R4Y3   W5JH80   A0A1Y9G9K8   A0A182WS83   A0A0M9ADA6   A0A182HL33   Q7PXQ1   A0A084W518   A0A182TM35   A0A182UQQ8   A0A182PGX5   A0A336M1D6   A0A182QXG8   A0A182NQD8   A0A210QQE1   A0A336MEZ9  

EC Number

3.6.4.13

Pubmed

19121390    28756777    26354079    22118469    18362917    19820115    + More
23537049    25348373    28004739    17994087    17550304    26108605    10731132    12537572    12537569    22936249    26483478    25315136    29403074    26823975    24495485    25830018    15632085    24845553    28648823    20075255    20566863    26334808    22992520    21347285    21719571    24508170    30249741    20798317    25244985    23254933    20966253    20920257    23761445    12364791    14747013    17210077    24438588    28812685   

EMBL

BABH01037755    KZ150278    PZC71642.1    GDQN01004285    JAT86769.1    KQ458879    + More
KPJ04681.1    AGBW02007656    OWR54810.1    NWSH01000060    PCG80062.1    KQ459249    KPJ02293.1    GEDC01015452    JAS21846.1    KQ971308    KYB29542.1    ABLF02033400    KB631615    ERL84685.1    KK854891    PTY19539.1    GAKP01022374    JAC36578.1    GEZM01017312    JAV90779.1    CH964168    EDW80157.2    CH891734    EDW99831.2    JRES01000371    KNC31881.1    KZ288227    PBC31829.1    CH902618    EDV40139.1    AE014296    BT016121    AY069270    CM002912    KMY99883.1    CM000363    EDX10614.1    CH954178    EDV52176.1    KQ414845    KOC60268.1    JXUM01119854    JXUM01119855    JXUM01119856    JXUM01119857    JXUM01119858    JXUM01119859    JXUM01119860    KQ566332    KXJ70227.1    GEBQ01008549    JAT31428.1    CH933809    EDW18798.1    PYGN01000456    PSN46005.1    CH916366    EDV97278.1    GDHC01007624    JAQ11005.1    GDHF01025525    JAI26789.1    CCAG010021136    CH940647    EDW70032.1    AJWK01014826    AJWK01014827    GAMC01014126    JAB92429.1    NEVH01005885    PNF38531.1    GBXI01016997    JAC97294.1    PNF38528.1    GFDL01012138    JAV22907.1    DS232258    EDS38587.1    GECZ01008908    JAS60861.1    ACPB03008382    CH379069    EAL30943.2    OUUW01000009    SPP85013.1    KK852636    KDR19736.1    LJIG01015965    KRT82021.1    NNAY01002835    OXU20469.1    AAZX01012231    DS235802    EEB17230.1    GBGD01000033    JAC88856.1    CP012525    ALC44797.1    JH432222    CVRI01000064    CRL05385.1    JH817099    EKC42919.1    KQ976480    KYM83762.1    KQ981440    KYN41656.1    ADTU01017656    ADTU01017657    ADTU01017658    ADTU01017659    ADTU01017660    ADTU01017661    GL888295    EGI63007.1    KQ977935    KYM98547.1    KK107364    QOIP01000007    EZA51912.1    RLU20421.1    GL446209    EFN88241.1    GL437183    EFN70894.1    KB203168    ESO86122.1    AXCM01000983    KQ982543    KYQ55377.1    ADMH02001504    ETN62280.1    KQ435694    KOX80923.1    APCN01000879    AAAB01008987    EAA00850.3    ATLV01020452    KE525302    KFB45312.1    UFQS01000410    UFQT01000410    SSX03677.1    SSX24042.1    AXCN02001526    NEDP02002410    OWF50966.1    UFQT01000821    SSX27373.1   

Proteomes

UP000005204    UP000053268    UP000007151    UP000218220    UP000007266    UP000007819    + More
UP000030742    UP000007798    UP000002282    UP000037069    UP000005203    UP000242457    UP000007801    UP000000803    UP000000304    UP000008711    UP000053825    UP000192221    UP000069940    UP000249989    UP000095301    UP000192223    UP000009192    UP000245037    UP000001070    UP000079169    UP000092445    UP000092444    UP000078200    UP000091820    UP000008792    UP000092461    UP000235965    UP000092443    UP000002320    UP000015103    UP000001819    UP000268350    UP000027135    UP000075901    UP000215335    UP000002358    UP000009046    UP000095300    UP000092553    UP000183832    UP000005408    UP000078540    UP000078541    UP000005205    UP000007755    UP000078542    UP000053097    UP000279307    UP000008237    UP000000311    UP000076408    UP000075920    UP000030746    UP000075883    UP000075809    UP000085678    UP000075880    UP000221080    UP000075881    UP000075882    UP000075900    UP000000673    UP000069272    UP000076407    UP000053105    UP000075840    UP000007062    UP000030765    UP000075902    UP000075903    UP000075885    UP000075886    UP000075884    UP000242188   

PRIDE

H9JGY1    Q9VUV9   

Pfam

PF18149   Helicase_PWI        + More
PF02889   Sec63
PF00270   DEAD
PF00271   Helicase_C

Interpro

IPR041094   Brr2_helicase_PWI        + More
IPR004179   Sec63-dom       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR014001   Helicase_ATP-bd       
IPR027417   P-loop_NTPase       
IPR014756   Ig_E-set       
IPR035892   C2_domain_sf       
IPR036390   WH_DNA-bd_sf       
IPR001650   Helicase_C       
IPR003593   AAA+_ATPase       
IPR003604   Matrin/U1-like-C_Znf_C2H2       

SUPFAM

SSF52540   SSF52540        + More
SSF46785   SSF46785       
SSF81296   SSF81296       

Gene 3D

2.60.40.150    

CDD

cd00079  HELICc

ProteinModelPortal

H9JGY1   A0A2W1B6C9   A0A1E1WID6   A0A0N1PHB0   A0A212FM88   A0A2A4K8S5   + More
A0A194Q9U6   A0A1B6D867   A0A139WNM0   J9K3Y5   U4U3Y2   A0A2R7WJ62   A0A034V4U5   A0A1Y1MYR1   B4N718   B4ITW8   A0A0L0CI23   A0A088AQI7   A0A2A3EKY9   B3M9U8   Q9VUV9   A0A0J9RW02   B4QLR5   B3NDP3   A0A0L7QNR8   A0A1W4VP22   A0A182H940   A0A1B6M691   A0A1I8MTD7   A0A1W4WLT7   B4KYI7   A0A2P8YP35   B4J3P7   A0A146LVA0   A0A0K8UJE3   A0A1S4ESM1   A0A1A9ZDE9   A0A1B0FDY4   A0A1A9UPZ3   A0A1A9WKU3   B4LDY9   A0A1B0CJP7   W8BT97   A0A2J7RCH7   A0A0A1WFR4   A0A2J7RCH2   A0A1A9XFP2   A0A1Q3F5S4   B0X1D8   A0A1B6GEL8   T1HLL0   Q2M0I9   A0A3B0JVC3   A0A067RJY2   A0A0T6B4B5   A0A182TAI4   A0A232EQ00   K7JA29   E0VV24   A0A069DYD2   A0A1I8Q351   A0A0M4EMC3   T1JH32   A0A1J1J3B5   K1RGJ6   A0A195BGJ6   A0A151JZT6   A0A158NJE4   F4WS28   A0A195CCL5   A0A026W729   E2B7U8   E2A6Q4   A0A182YAH9   A0A182VWG1   V3ZP59   A0A182MTI2   A0A151X4T3   A0A2R2MMN6   A0A182IVX8   A0A2D0QYR1   A0A182JU03   A0A182L9F5   A0A182R4Y3   W5JH80   A0A1Y9G9K8   A0A182WS83   A0A0M9ADA6   A0A182HL33   Q7PXQ1   A0A084W518   A0A182TM35   A0A182UQQ8   A0A182PGX5   A0A336M1D6   A0A182QXG8   A0A182NQD8   A0A210QQE1   A0A336MEZ9  

PDB

6QX9     E-value=1.83302e-52,     Score=518

KEGG

101736002    K12854 pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13] | (RefSeq) putative U5 small nuclear ribonucleo

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0004386   GO:0003676   GO:0005524   GO:0046540   GO:0004004   GO:0000388   GO:0071013   GO:0071014   GO:0000398   GO:0005682   GO:0008026   GO:0005681   GO:0005634   GO:0000381   GO:0030532   GO:0007283   GO:0007419   GO:0000278   GO:0071011   GO:0008380   GO:0003724   GO:0016021   GO:0008270  

Subcellular location

Nucleus  

Length:

257

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.09255

outside

1  -  257

 

 

Pi

412.107312

Theta

207.993323

Tajima's D

3.166385

CLR

0

CSRT

0.984550772461377

Interpretation

Uncertain