SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO14610  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA008779
Annotation
Putative_U5_small_nuclear_ribonucleoprotein_200_kDa_helicase_[Papilio_xuthus]
Full name
Putative U5 small nuclear ribonucleoprotein 200 kDa helicase      
Alternative Name
Protein lethal (3) 72Ab
Location in the cell
Cytoplasmic   Reliability : 1.951
 

Sequence

CDS
ATGTCCGTCGCGAACAGCTATTGGCTGAGCGAGGAGCAAATTAACAAACGCCACTCACAGTCTCTGCATCCGATGGATATAGATGCTTACTGGCTGCAGAGACGACTGTCCAGACATTTTCCTGACGCTATGCTGTCTCAGGCGAAATCCACGGACGTGCTGAAGGCGCTCGCCGAGGCTGCCGACGACAGAGACCTGGAGAACAGGCTGGTCCTGCTGCTCGGTTACGACTGCTTCGACTTCGTCAAGATATTGAACAAGTACAGGTTCATGATCCTGTATTGCACGAAGCTGGCGTCCTCCCAGTCGGAGAGCGAGCGCGTGTCGATACGTGAGGAGATGTCCCGGCAGCCTCACCTGCAGAAGATCCTCGCGCAATTGGAGACCGGCAATGGAGATGATGAGAAAATGGATACTCACTCTGAGGCCCCTCGAAAGAGGCACAAATCTGAAGCCGAGAGCAGCTCTACATCTGGGCAGGTAGCGGGTTCTAGGAAGGTGGTGCAGCTCGAGGACCTGGTGTTCGCGGCTGGATCGCACTTCATGGCCAACAAGAGGTGCCAGCTGCCACCGGGTTCATTCAGGAAGCAGCGGAAAGGTTACGAAGAAGTCCACGTGCCGGCTCTGAAACCGAAGCCGTTTGAAGAAAACGAGACACTAGTGCCGATCGAGAAGCTGCCCAAATACGTCCAGCCAGCGTTCGAGGGATTCAAGACCCTGAATAGAATACAGAGCCGCATATCGAAGCCGGCGCTGGAGTCGGACGAGAATCTGCTGGTGTGCGCGCCCACCGGGGCCGGCAAGACCAACGTGGCGCTGCTGTGCGTGCTTCGCGAGGTCGGCAAGCACGTCAACGACGACGGCACTGTCAATGTCAACGACTTCAAGATGATATACGTCGCGCCGATGCGCTCGCTCGTGCAGGAAATGGTGGGCAACTTCAGCAAGCGTCTGTCCGCTTACAACATGAAGGTCTCCGAGTTGACCGGCGACCACCAGCTCACGAGGGAGCAGATCGAGGCCACGCAGCTCATCGTGTGCACTCCGGAGAAGTGGGACATCATCACCAGGAAGGGCGGTGAGCGCTCCTTCACGAACCTGGTCCGGCTTATAATCATAGACGAGGTCCACTTGTTGCACGACGAGCGCGGGCCCGTGCTGGAGGCGCTGGTGGCGCGGACCCTGCGGACGGTCGAGCAGACTCGGGAGGAGGTGCGGCTCGTGGGCCTATCCGCCACGCTGCCTAACTACACGGACGTGGCCACCTTCCTGCGCGTACGACCCGAGAAGGGACTCTTCTACTTCGACAACTCCTTCAGACCGGTGGCCCTCGAGCAGCAGTACATCGGCGTGACGGAGAAGAAGGCTCTCAAGCGGTTCCAGGTGATGAACGACATCGTCTACGAGAAGGTGATGGAGCACGCAGGCAAGAACCAGATATTAGTGTTCGTCCACTCGCGCAAGGAGACCGGGAAGACGGCGCGCGCGATCCGCGACATGTGCCTCGAGAAGGACACGCTTGGACACTTTTTGAGAGAGGGGTCGGCTAGTATGGAGGTCCTGCGCACTGAGGCCGAGCAGGTCAAGAACCCTGAGCTGCGGGAGCTGCTGCCGTACAGCTTCGCCATACATCACGCCGGCATGAGCAGGGTGGACAGGACGCTGGTCGAGGATCTGTTCGCTGATAGGCACATACAGGTGCTGGTGTCGACGGCGACCTTAGCGTGGGGCGTGAACCTGCCCGCGCACACCGTCATCGTGAAGGGCACGCAGGTGTACTGCCCCGAGAAGGGCCGCTGGACAGAGCTGGGCGCGCTCGACGTGCTGCAGATGCTAGGCCGCGCCGGGAGACCGCAGTACGACACCAAGGGAGAAGGCATCCTGATAACGAACCACTCGGAGCTGCAGTACTACCTGTCGCTGCTGAACCAGCAGCTGCCCATAGAGTCGCAGCTGGTGAGCAAGTTGCCGGACATGCTGAACGCGGAGATCGTGCTGGGCTCGGTGCAGAGCGTCCGGGACGCCGTCACGTGGCTGGGCTACACGTATCTATACATCCGCATGCTGAGGCAGCCGGCGCTGTACGGAGTCTCCCCGGAGAAGATGCAGGACGACAATCTGCTGGAACTGCACCGTGCCGACCTGGTGCACACCGCCGCCAGTCTACTGGACAAGGCCGGCCTGATCAAATACGAGAAGAAGTCCGGCCACTTCCAGCCGACGGAGCTGGGCCGCATCGCCTCGCACTTCTACTGCACGTACGAGACGATGCAGTCGTACAACCAGCTGCTGAAGCCGACGCTCGGCGAGATCGAGCTGTTCCGCGTGTTCTCGCTCTCCGCCGAGTTCAAGCACATCGCCGTCCGCGAGGAGGAGAAGCTGGAGCTGCATAAGCTCATGGAGAGGGTGCCGATCCCTATAAAGGAGAGCATAGAGGAGTCCTCGGCGAAGATCAACGTGCTGCTGCAGGCGTACATCTCGCAGCTGAAGCTCGAGGGGTTCGCGCTGATGGCGGACATGGTGTACGTCACGCAGTCCGCCTGCAGGCTGCTCAGGGCCATCTTCGAGATTGTACTGTACAGAGGCTGGGCGCAGCTGGTGGACAAAACACTGGCGCTGTGCAAGATGGTGGACAGAAGGATGTGGCAGTCCATGTCGCCGTTGAGACAGTTTAAGAAGATACCCGAAGAGATAGGTGTCTAA
Protein
MSVANSYWLSEEQINKRHSQSLHPMDIDAYWLQRRLSRHFPDAMLSQAKSTDVLKALAEAADDRDLENRLVLLLGYDCFDFVKILNKYRFMILYCTKLASSQSESERVSIREEMSRQPHLQKILAQLETGNGDDEKMDTHSEAPRKRHKSEAESSSTSGQVAGSRKVVQLEDLVFAAGSHFMANKRCQLPPGSFRKQRKGYEEVHVPALKPKPFEENETLVPIEKLPKYVQPAFEGFKTLNRIQSRISKPALESDENLLVCAPTGAGKTNVALLCVLREVGKHVNDDGTVNVNDFKMIYVAPMRSLVQEMVGNFSKRLSAYNMKVSELTGDHQLTREQIEATQLIVCTPEKWDIITRKGGERSFTNLVRLIIIDEVHLLHDERGPVLEALVARTLRTVEQTREEVRLVGLSATLPNYTDVATFLRVRPEKGLFYFDNSFRPVALEQQYIGVTEKKALKRFQVMNDIVYEKVMEHAGKNQILVFVHSRKETGKTARAIRDMCLEKDTLGHFLREGSASMEVLRTEAEQVKNPELRELLPYSFAIHHAGMSRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIVKGTQVYCPEKGRWTELGALDVLQMLGRAGRPQYDTKGEGILITNHSELQYYLSLLNQQLPIESQLVSKLPDMLNAEIVLGSVQSVRDAVTWLGYTYLYIRMLRQPALYGVSPEKMQDDNLLELHRADLVHTAASLLDKAGLIKYEKKSGHFQPTELGRIASHFYCTYETMQSYNQLLKPTLGEIELFRVFSLSAEFKHIAVREEEKLELHKLMERVPIPIKESIEESSAKINVLLQAYISQLKLEGFALMADMVYVTQSACRLLRAIFEIVLYRGWAQLVDKTLALCKMVDRRMWQSMSPLRQFKKIPEEIGV

Summary

Description
Putative RNA helicase involved in the second step of RNA splicing.
Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
Similarity
Belongs to the helicase family. SKI2 subfamily.
Keywords
ATP-binding   Complete proteome   Helicase   Hydrolase   mRNA processing   mRNA splicing   Nucleotide-binding   Nucleus   Reference proteome   Repeat   Spliceosome  
Feature
chain  Putative U5 small nuclear ribonucleoprotein 200 kDa helicase
EC Number
3.6.4.13
EMBL
GAIX01013847    JAA78713.1    KQ459249    KPJ02293.1    KQ435694    KOX80923.1    + More
KQ414845    KOC60268.1    GL437183    EFN70894.1    GECZ01008908    JAS60861.1    KZ288227    PBC31829.1    LBMM01003333    KMQ93648.1    GL446209    EFN88241.1    KQ977935    KYM98547.1    KQ976480    KYM83762.1    ADTU01017656    ADTU01017657    ADTU01017658    ADTU01017659    ADTU01017660    ADTU01017661    AJWK01014826    AJWK01014827    GDHF01025525    JAI26789.1    GBXI01016997    JAC97294.1    ABLF02033400    KK107364    QOIP01000007    EZA51912.1    RLU20421.1    LJIG01015965    KRT82021.1    GAMC01014126    JAB92429.1    KQ971308    KYB29542.1    KK852636    KDR19736.1    GEZM01017312    JAV90779.1    NEVH01005885    PNF38528.1    PNF38531.1    AAZX01012231    CCAG010021136    JRES01000371    KNC31881.1    NNAY01002835    OXU20469.1    KQ982543    KYQ55377.1    UFQT01000821    SSX27373.1    DS235802    EEB17230.1    KQ981440    KYN41656.1    CH477735    EAT36755.1    CH916366    EDV97278.1    JXUM01110490    JXUM01110491    JXUM01110492    JXUM01110493    KQ565417    KXJ71002.1    DS232258    EDS38587.1    GFDL01012138    JAV22907.1    GL888295    EGI63007.1    GFTR01008922    JAW07504.1    GBGD01000033    JAC88856.1    ADMH02001504    ETN62280.1    GGFK01003111    MBW36432.1    ATLV01020452    KE525302    KFB45312.1    OUUW01000009    SPP85013.1    CH964168    EDW80157.2    KB631615    ERL84685.1    CH933809    EDW18798.1    CH902618    EDV40139.1    GDHC01007624    JAQ11005.1    APGK01048231    APGK01048232    APGK01048233    APGK01048234    APGK01048235    APGK01048236    APGK01048237    APGK01048238    APGK01048239    KB741102    ENN73865.1    CH954178    EDV52176.1    AE014296    BT016121    AY069270    CH940647    EDW70032.1    CM000363    EDX10614.1    GBHO01037849    JAG05755.1    APGK01013186    APGK01013187    APGK01013188    APGK01013189    APGK01013190    APGK01013191    APGK01013192    KB738934    ENN82430.1    CM002912    KMY99883.1    AXCM01000983    AAAB01008987    EAA00850.3    APCN01000879    CP012525    ALC44797.1    GBRD01016477    GBRD01016476    JAG49349.1    AXCN02001526    CH379069    EAL30943.2    KK854891    PTY19539.1    ACPB03008382    GFPF01010756    MAA21902.1    JH432222    CM004471    OCT86629.1    GBBM01000407    JAC35011.1    GACK01005418    JAA59616.1    GFAC01003440    JAT95748.1    GEDV01009742    JAP78815.1    GGLE01005488    MBY09614.1    GL766582    EFZ15034.1    AAMC01014036    AAMC01014037    GDAY02002782    JAV48685.1   
Pfam
PF18149   Helicase_PWI        + More
PF00270   DEAD
PF00271   Helicase_C
PF02889   Sec63
PF16113   ECH_2
Interpro
IPR036390   WH_DNA-bd_sf        + More
IPR041094   Brr2_helicase_PWI       
IPR004179   Sec63-dom       
IPR001650   Helicase_C       
IPR035892   C2_domain_sf       
IPR014756   Ig_E-set       
IPR027417   P-loop_NTPase       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR014001   Helicase_ATP-bd       
IPR003593   AAA+_ATPase       
IPR003604   Matrin/U1-like-C_Znf_C2H2       
IPR032259   HIBYL-CoA-H       
IPR029045   ClpP/crotonase-like_dom_sf       
SUPFAM
SSF52540   SSF52540        + More
SSF81296   SSF81296       
SSF46785   SSF46785       
SSF52096   SSF52096       
Gene 3D
PDB
6QX9     E-value=0,     Score=3354

Ontologies

Topology

Subcellular location
Nucleus  
Length:
900
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.04621
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00029
outside
1  -  900
 
 

Population Genetic Test Statistics

Pi
267.188163
Theta
170.544249
Tajima's D
1.83358
CLR
0.152938
CSRT
0.849207539623019
Interpretation
Uncertain
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