Gene

KWMTBOMO14608  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008779

Annotation

PREDICTED:_putative_U5_small_nuclear_ribonucleoprotein_200_kDa_helicase_[Papilio_xuthus]

Location

Bomo_Chr24(-):11160016-11182643      View in EpiBrowser

Full name

Putative U5 small nuclear ribonucleoprotein 200 kDa helicase      

Alternative Name

Protein lethal (3) 72Ab

Location in the cell

Cytoplasmic   Reliability : 1.08 Mitochondrial   Reliability : 1.157

CDS

ATGTCCGGGAGCTACTCGCTTGTGACTCATCTTAAACGCATCTCGTGCCCCCAGGTCATAAAGAAACTCGAGAAGAAGAACTTCCCGTGGGAGAAGCTGTACGAGCTGGGCCCCAACGAGATCGGCGAGCTGGTCCGCGCTCCGAAGCTGGGCAAGATGCTGCACAAGTACGTGCACCAGTTCCCGAAGCTGGAGCTCGCGACGCACATCCAGCCCATCACCAGGTCGACGCTCAGGGTCGAGCTCACCATCACGCCGGACTTCCATTGGGACGAGAAAATCCACGGACAGTCGGAGGCGTTCTGGATCCTGGTGGAGGACGTGGACTCTGAGGTGATCCTCCACCACGAGTATTTCCTGCTCAAGCAGAAGTACTGCAAGGACGAGCACCAGGTGAAGCTGTTCGTGCCGGTCTTCGAGCCCCTGCCTCCTCAGTACTTCCTGAGGGTCGTGTCCGATAGATGGATAGCAGCGGAGACGCAGCTTCCGGTGTCGTTCCGGCACCTCATCCTGCCCGAGAAGAACTTCCCGCCGACCGAGCTGCTGGACCTGCAGCCGCTGCCCATCTCGGCACTCCGGAATGCCAAGTACGAGGAGCTGTACAACGACACCTTCCCGCAGTTCAACCCGGTGCAGACGCAGGTGTTCAACGCAGTGTACAACTCTGACGACAACGTGTTCGTGGGTGCGCCGTCGGGCTCGGGCAAGTCGCTGGTTGCGGAGCTGGCGCTGCTGCGGATGCTGTCCCGGGACGCGGGCGGGCGCGCCGTGTACCTGCTGCCCAAGGACGCGCTGGCGGACATCGTGTTCGCGCACTGCTACCACAAGTTCGGGACCAAGTTCAATCTTAAGGTGGTCCAGCTGACCGGCGAGACTGCTACGGACCACAAGCTGCTCAACAAAGGCCAGATCATCATAACGACGGCCGATAAGTGGGACATACTCTCCCGGAGATGGAAAGTACGCAAGAGCGTCCAGAGCGTGTCGCTGCTGATCGCGGACGCGCTGCAGCTGCTGGGCGGCGAGGAGGGGCCGGTCGTGGAGGTGGTCTGCTCTAGGATGAGGTACATCGCCTCTCAGACAGGGAAGCCGATCCGTATAGTGGCCCTGTCGCTACCGCTGGCCGACGCCCGCGACGTTGCCCAGTGGCTCGGCTGCAACGCGAATGCCACCTTCAATTTCCACCCTAGCGTCAGATCCCTCCCACTAGAGTTGCACATCCAGGGCTTCAACATATCGCACGCGCCGACCCGGCTGACGGCCATGACGAAGCCCATCTACAACGCGATCCGGCGGCACGCGGGCACCCGCCCCTGCGCAGTGTTCGTGAGCTCGCGCCGCGCCGCCCGCCTGCTCGCCGCCGACCTGCTGGCGCTGGCGGCCGCGCGCGCAGCCCCCGCCGCCTTCCTGCACGCCTCGCGCGACCTGCTCGCGCCCTTCCTCGACGCCGTGCAGGACAAGATGCTGAAGGAGACGCTGTCCGCGGGCGTGGCGTACCTGCACGCGGGCGTGTCCGCCGGCGACCGGCGCGTGGTGCAGCAGCTGGTAGAGTGCGGCGCCGCGCAGCTGTGCGTGGTCGCCGCCGAGCTGGCCTGGAGCTTCGCCGCGCACGTGCACACCGTCATCGTGGCCGACACGTGCACGTACAACGGCAAGCTGCACTCGTACGAGCAGTACCCGATAACGACGGTGCTGCAGATGATCGGGCGCGCGTGCCGCCCGCTGGAGGACGACCACTCGGTGGCGGTGCTCATGTGCGCCGCGCACCACAAGACCTTCTTCACCAAGTTGCTCAACGACTGTCTGCCGCTGGAGAGTCACTTGGACCACAGACTCCACGATCACATGAACGCCGAGATAGTGACGAAGACCATAGAGAACAAGCAAGACGCCGTCGACTACTTGACCTGGACATTCCTGTACCGGCGGCTCACGCAGAACCCCAACTACTACAACTTACAGGGGGTCACGCACAGGCACCTGTCGGACCACCTCTCCGAGCTGGTGGAGACTACGCTGACGGATCTTGAGCAGTCCAAGTGCATCGCGATAGAGGATGAAATGGATGTCCAGCCACTGAACTTGGGGATGATAGCCTCATACTACTATATCAACTATACGACCATAGAACTGTTTAGTTTGTCTCTGACGAGCAAAACGAAGATCCGCGGCCTGCTCGAGATAATATCGTCGGCGGCCGAGTACTCGGACCTCTGCATCCGACACCGGGAGGAGAACATCATCAAATCTCTCGCCTCCAAGGTCCCGCACAAGCCGACGGCCCCGTCTGGCGGCGCCGTGCGGCACAACGACCCGCACGTGAAGGCGCACGTGCTGCTCCAGGCGCACCTCTCCAGGATGCAACTACCCGCCGAGCTGCAGGCCGACACCGCGCTCGTGCTCACCAAGGCGCTTCGGCTGATCCAGGCGTGCGTGGACGTGGTGTCCAGCAGCGGGTGGCTGGCGCCCGCCGTGGCCGCCATGGAGCTAGCCCAGATGGTGACGCAGGCCATGTGGGCCAAGGACTCGTACCTAAGGCAGCTGCCGCACTTCACGCCCGAGCTGGTGCAACGCTGCGCTGACAAGGGCGTGGAGACCGTGTTCGACGTGATGGAGCTGGAGGACACCGCCAGAGCCAAGCTGCTGCAGCTGTCTCCCGCCGAGATGGCAGACGTGGCGCGCTTCTGTAACCGGTACCCCAACGTGGAGCTCAACTATGAGGTGAAGAACGAGCGCCACCTGCGCGCCGGGAAGCCGATCGTGGTGGAGGTTTCGCTGGAGAGGGAGGACGACGTCCTCGGCCCGGTCATAGCGCCCTTCTTCCCCCAGAAACGCGAGGAGGGCTGGTGGGTCGTGATCGGAGACCCCAAGAGCAACACGCTGCTCTCCATCAAGCGGGTGTCGCTGGCCAGGAGCGCCAAGGTCCGGCTGGACTTCGTGTGTGGCGGCGCGGGGCGGCACACGTACACCCTGTACTTCATGTCCGACGCGTACCTAGGTGCCGACCAGGAGTACAAGTTCAACGTTGAGGTGGCAGACGCGGCGTCCGACTCCAGCGAGGACTCGGACCAGTACGGCTGA

Protein

MSGSYSLVTHLKRISCPQVIKKLEKKNFPWEKLYELGPNEIGELVRAPKLGKMLHKYVHQFPKLELATHIQPITRSTLRVELTITPDFHWDEKIHGQSEAFWILVEDVDSEVILHHEYFLLKQKYCKDEHQVKLFVPVFEPLPPQYFLRVVSDRWIAAETQLPVSFRHLILPEKNFPPTELLDLQPLPISALRNAKYEELYNDTFPQFNPVQTQVFNAVYNSDDNVFVGAPSGSGKSLVAELALLRMLSRDAGGRAVYLLPKDALADIVFAHCYHKFGTKFNLKVVQLTGETATDHKLLNKGQIIITTADKWDILSRRWKVRKSVQSVSLLIADALQLLGGEEGPVVEVVCSRMRYIASQTGKPIRIVALSLPLADARDVAQWLGCNANATFNFHPSVRSLPLELHIQGFNISHAPTRLTAMTKPIYNAIRRHAGTRPCAVFVSSRRAARLLAADLLALAAARAAPAAFLHASRDLLAPFLDAVQDKMLKETLSAGVAYLHAGVSAGDRRVVQQLVECGAAQLCVVAAELAWSFAAHVHTVIVADTCTYNGKLHSYEQYPITTVLQMIGRACRPLEDDHSVAVLMCAAHHKTFFTKLLNDCLPLESHLDHRLHDHMNAEIVTKTIENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVTHRHLSDHLSELVETTLTDLEQSKCIAIEDEMDVQPLNLGMIASYYYINYTTIELFSLSLTSKTKIRGLLEIISSAAEYSDLCIRHREENIIKSLASKVPHKPTAPSGGAVRHNDPHVKAHVLLQAHLSRMQLPAELQADTALVLTKALRLIQACVDVVSSSGWLAPAVAAMELAQMVTQAMWAKDSYLRQLPHFTPELVQRCADKGVETVFDVMELEDTARAKLLQLSPAEMADVARFCNRYPNVELNYEVKNERHLRAGKPIVVEVSLEREDDVLGPVIAPFFPQKREEGWWVVIGDPKSNTLLSIKRVSLARSAKVRLDFVCGGAGRHTYTLYFMSDAYLGADQEYKFNVEVADAASDSSEDSDQYG

Description

Putative RNA helicase involved in the second step of RNA splicing.

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Similarity

Belongs to the helicase family. SKI2 subfamily.

Keywords

ATP-binding   Complete proteome   Helicase   Hydrolase   mRNA processing   mRNA splicing   Nucleotide-binding   Nucleus   Reference proteome   Repeat   Spliceosome  

Feature

chain  Putative U5 small nuclear ribonucleoprotein 200 kDa helicase

Uniprot

A0A1W4WLT7   A0A139WNM0   A0A1I8MTD7   A0A1I8Q351   A0A1Y1MYR1   B0X1D8   + More
T1PLJ4   A0A0A1WFR4   A0A0L0CI23   W8BT97   A0A182R4Y3   A0A0K8UJE3   A0A1Q3F5S4   A0A182VWG1   A0A182NQD8   A0A2J7RCH2   A0A182QXG8   A0A182YAH9   A0A182PGX5   A0A182MTI2   A0A084W518   A0A1S4FSY9   Q16QS5   A0A067RJY2   A0A182UQQ8   A0A182IVX8   A0A2J7RCH6   A0A336MEZ9   A0A182TM35   A0A182WS83   A0A182JU03   Q7PXQ1   A0A1Y9G9K8   A0A1B0FDY4   A0A182HL33   W5JH80   A0A1A9UPZ3   A0A1A9ZDE9   A0A182T6K2   A0A2M4A6R2   N6TX23   A0A1A9XFP2   A0A2P8YP35   A0A182H4Y4   B4KYI7   A0A1B0B7S0   A0A1A9WKU3   B4LDY9   A0A0M4EMC3   A0A2A3EKY9   A0A1B0D9F3   A0A1W4VP22   B3M9U8   B4J3P7   Q9VUV9   A0A0J9RW02   E9IWL3   A0A1B6C919   B3NDP3   F4WS28   E2B7U8   B4HIL1   A0A158NJE4   A0A195CCL5   B4PD16   B4N718   Q2M0I9   A0A026W729   A0A0J7KTK4   E2A6Q4   A0A3B0JVC3   A0A2J7RCH7   J9K3Y5   A0A087TVN5   A0A0L7QNR8   A0A0C9R8Q1   A0A0T6B4B5   U4U3Y2   A0A1S3IYW6   A0A023GME8   A0A1J1J3B5   A0A232EQ00   K7JA29   A0A131YJT3   L7M5R0   A0A1B0CJP7   A0A2R5LJE3   A0A224Z6E7   A0A1Z5KU77   A0A1E1X934   A0A226MD86   A0A3B3T1P8   A0A3B3T081   R0LG86   H2RSA0   A0A293MXH2   A0A3B3SZX8   A0A3B3T1E4   A0A1W5ALR0   A0A3Q3LQG7  

EC Number

3.6.4.13

Pubmed

18362917    19820115    25315136    28004739    25830018    26108605    + More
24495485    25244985    24438588    17510324    24845553    12364791    14747013    17210077    20920257    23761445    23537049    29403074    26483478    17994087    10731132    12537572    12537569    22936249    21282665    21719571    20798317    21347285    17550304    15632085    24508170    30249741    28648823    20075255    26830274    25576852    28797301    28528879    28503490    29240929    21551351   

EMBL

KQ971308    KYB29542.1    GEZM01017312    JAV90779.1    DS232258    EDS38587.1    + More
KA648950    AFP63579.1    GBXI01016997    JAC97294.1    JRES01000371    KNC31881.1    GAMC01014126    JAB92429.1    GDHF01025525    JAI26789.1    GFDL01012138    JAV22907.1    NEVH01005885    PNF38528.1    AXCN02001526    AXCM01000983    ATLV01020452    KE525302    KFB45312.1    CH477735    EAT36755.1    KK852636    KDR19736.1    PNF38530.1    UFQT01000821    SSX27373.1    AAAB01008987    EAA00850.3    CCAG010021136    APCN01000879    ADMH02001504    ETN62280.1    GGFK01003111    MBW36432.1    APGK01048231    APGK01048232    APGK01048233    APGK01048234    APGK01048235    APGK01048236    APGK01048237    APGK01048238    APGK01048239    KB741102    ENN73865.1    PYGN01000456    PSN46005.1    JXUM01110490    JXUM01110491    JXUM01110492    JXUM01110493    KQ565417    KXJ71002.1    CH933809    EDW18798.1    JXJN01009710    CH940647    EDW70032.1    CP012525    ALC44797.1    KZ288227    PBC31829.1    AJVK01028188    AJVK01028189    CH902618    EDV40139.1    CH916366    EDV97278.1    AE014296    BT016121    AY069270    CM002912    KMY99883.1    GL766582    EFZ15034.1    GEDC01027568    JAS09730.1    CH954178    EDV52176.1    GL888295    EGI63007.1    GL446209    EFN88241.1    CH480815    EDW41641.1    ADTU01017656    ADTU01017657    ADTU01017658    ADTU01017659    ADTU01017660    ADTU01017661    KQ977935    KYM98547.1    CM000159    EDW94948.2    CH964168    EDW80157.2    CH379069    EAL30943.2    KK107364    QOIP01000007    EZA51912.1    RLU20421.1    LBMM01003333    KMQ93648.1    GL437183    EFN70894.1    OUUW01000009    SPP85013.1    PNF38531.1    ABLF02033400    KK116951    KFM69174.1    KQ414845    KOC60268.1    GBYB01012739    JAG82506.1    LJIG01015965    KRT82021.1    KB631615    ERL84685.1    GBBM01000407    JAC35011.1    CVRI01000064    CRL05385.1    NNAY01002835    OXU20469.1    AAZX01012231    GEDV01009742    JAP78815.1    GACK01005418    JAA59616.1    AJWK01014826    AJWK01014827    GGLE01005488    MBY09614.1    GFPF01010756    MAA21902.1    GFJQ02008323    JAV98646.1    GFAC01003440    JAT95748.1    MCFN01001355    OXB53211.1    KB743182    EOB00570.1    GFWV01020794    MAA45522.1   

Proteomes

UP000192223    UP000007266    UP000095301    UP000095300    UP000002320    UP000037069    + More
UP000075900    UP000075920    UP000075884    UP000235965    UP000075886    UP000076408    UP000075885    UP000075883    UP000030765    UP000008820    UP000027135    UP000075903    UP000075880    UP000075902    UP000076407    UP000075881    UP000007062    UP000069272    UP000092444    UP000075840    UP000000673    UP000078200    UP000092445    UP000075901    UP000019118    UP000092443    UP000245037    UP000069940    UP000249989    UP000009192    UP000092460    UP000091820    UP000008792    UP000092553    UP000242457    UP000092462    UP000192221    UP000007801    UP000001070    UP000000803    UP000008711    UP000007755    UP000008237    UP000001292    UP000005205    UP000078542    UP000002282    UP000007798    UP000001819    UP000053097    UP000279307    UP000036403    UP000000311    UP000268350    UP000007819    UP000054359    UP000053825    UP000030742    UP000085678    UP000183832    UP000215335    UP000002358    UP000092461    UP000198323    UP000261540    UP000005226    UP000192224    UP000261640   

PRIDE

Q9VUV9    L7M5R0   

Pfam

PF18149   Helicase_PWI        + More
PF00271   Helicase_C
PF00270   DEAD
PF02889   Sec63
PF16113   ECH_2

Interpro

IPR011545   DEAD/DEAH_box_helicase_dom        + More
IPR035892   C2_domain_sf       
IPR014001   Helicase_ATP-bd       
IPR001650   Helicase_C       
IPR036390   WH_DNA-bd_sf       
IPR041094   Brr2_helicase_PWI       
IPR003593   AAA+_ATPase       
IPR027417   P-loop_NTPase       
IPR014756   Ig_E-set       
IPR004179   Sec63-dom       
IPR003604   Matrin/U1-like-C_Znf_C2H2       
IPR032259   HIBYL-CoA-H       
IPR029045   ClpP/crotonase-like_dom_sf       

SUPFAM

SSF52540   SSF52540        + More
SSF81296   SSF81296       
SSF46785   SSF46785       
SSF52096   SSF52096       

Gene 3D

2.60.40.150    

CDD

cd00079  HELICc

ProteinModelPortal

A0A1W4WLT7   A0A139WNM0   A0A1I8MTD7   A0A1I8Q351   A0A1Y1MYR1   B0X1D8   + More
T1PLJ4   A0A0A1WFR4   A0A0L0CI23   W8BT97   A0A182R4Y3   A0A0K8UJE3   A0A1Q3F5S4   A0A182VWG1   A0A182NQD8   A0A2J7RCH2   A0A182QXG8   A0A182YAH9   A0A182PGX5   A0A182MTI2   A0A084W518   A0A1S4FSY9   Q16QS5   A0A067RJY2   A0A182UQQ8   A0A182IVX8   A0A2J7RCH6   A0A336MEZ9   A0A182TM35   A0A182WS83   A0A182JU03   Q7PXQ1   A0A1Y9G9K8   A0A1B0FDY4   A0A182HL33   W5JH80   A0A1A9UPZ3   A0A1A9ZDE9   A0A182T6K2   A0A2M4A6R2   N6TX23   A0A1A9XFP2   A0A2P8YP35   A0A182H4Y4   B4KYI7   A0A1B0B7S0   A0A1A9WKU3   B4LDY9   A0A0M4EMC3   A0A2A3EKY9   A0A1B0D9F3   A0A1W4VP22   B3M9U8   B4J3P7   Q9VUV9   A0A0J9RW02   E9IWL3   A0A1B6C919   B3NDP3   F4WS28   E2B7U8   B4HIL1   A0A158NJE4   A0A195CCL5   B4PD16   B4N718   Q2M0I9   A0A026W729   A0A0J7KTK4   E2A6Q4   A0A3B0JVC3   A0A2J7RCH7   J9K3Y5   A0A087TVN5   A0A0L7QNR8   A0A0C9R8Q1   A0A0T6B4B5   U4U3Y2   A0A1S3IYW6   A0A023GME8   A0A1J1J3B5   A0A232EQ00   K7JA29   A0A131YJT3   L7M5R0   A0A1B0CJP7   A0A2R5LJE3   A0A224Z6E7   A0A1Z5KU77   A0A1E1X934   A0A226MD86   A0A3B3T1P8   A0A3B3T081   R0LG86   H2RSA0   A0A293MXH2   A0A3B3SZX8   A0A3B3T1E4   A0A1W5ALR0   A0A3Q3LQG7  

PDB

6QX9     E-value=0,     Score=3602

KEGG

101736137    K12854 pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13] | (RefSeq) putative U5 small nuclear ribonucleo

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0003676   GO:0004386   GO:0005524   GO:0046540   GO:0004004   GO:0000388   GO:0071013   GO:0071014   GO:0000398   GO:0005682   GO:0008026   GO:0005681   GO:0005634   GO:0008270   GO:0003860   GO:0016021   GO:0000381   GO:0030532   GO:0007283   GO:0007419   GO:0000278   GO:0071011   GO:0008380   GO:0003724   GO:0042802   GO:0005654   GO:0005515   GO:0003677   GO:0006101   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

Subcellular location

Nucleus  

Length:

1026

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0573300000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00017

outside

1  -  1026

 

 

Pi

255.519491

Theta

175.522474

Tajima's D

1.838676

CLR

0.212611

CSRT

0.849357532123394

Interpretation

Uncertain