Gene

KWMTBOMO14600

Annotation

ferritin_precursor_[Bombyx_mori]

Location

Bomo_Chr24(+):11078134-11091510      View in EpiBrowser

Full name

Ferritin      

Location in the cell

Extracellular   Reliability : 2.715

CDS

ATGAGGGCTGTTTTCTTTGCTGTCCTCGGACTCGTTGCTGCCCTAGCTCCTGCCACAGCTACACAGTGTTACGTCAGCCCCGTCACCATCAGGGATGAGTGGCTCACCATGGAGCAGACTTGCTACAACATGATGAGGAAACAGATCCAGGAGGAAGTGGCCGCGTCAATCCAGTACTTAGCCATGGGGGCTTACTTCTCGATCGATACGGCCCCCGCAAACACGTCGTGGGAGAGCGGCGCATCAGCCCTCGAGCACGCCCTCAAGCTGGAGAGTGACGTCACCAACAGCATCCGGGAGGTCATCAAGACCTGCGAGAGCAGCTTCAACGACTACCACCTGGTCGACTATTTGTCCGGGGAATTCCTCGACGAACAGTACAAGGGCCAACGCGACCTCGCCGGCAAGGCCTCGACCCTCAAGAAGATGATGGACAAACACGCCGCCCTCGGAGAGTTCATCTTCGACAAGAAACTCCTCGGATTGAACGTATAA

Protein

MRAVFFAVLGLVAALAPATATQCYVSPVTIRDEWLTMEQTCYNMMRKQIQEEVAASIQYLAMGAYFSIDTAPANTSWESGASALEHALKLESDVTNSIREVIKTCESSFNDYHLVDYLSGEFLDEQYKGQRDLAGKASTLKKMMDKHAALGEFIFDKKLLGLNV

Description

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

Catalytic Activity

4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O

Similarity

Belongs to the ferritin family.

Feature

chain  Ferritin

Uniprot

Q1HQ56   Q06FJ5   H9JGX1   Q9GQW5   Q8WQX3   A0A0K8TC38   + More
A0A0N1IPY3   I4DJ24   I4DM68   A0A1E1W8M6   A0A2H1VER5   A0A1E1W9G2   S4NTX6   A0A212FM21   Q9TVR3   A9NJI5   A0A2A4JK48   A0A2W1C098   A0A2P8YY31   A0A1V1G5M1   Q5MGP3   Q7Z161   A0A1W4WWM1   A0A2D1AEE0   R4FL73   A0A2H4N0Q4   A0A2K8JSG7   V5GNT8   A0A2J7Q081   A0A171A5W7   A0A140DKV8   A8CAE8   R4UJT6   A0A1L8DJC8   Q8MUX0   A0A224XXB4   T1HTF0   T1HYY6   A0A1D1YFD4   A0A0C9RXN6   A0A026VVU9   A0A232FKJ7   A0A1B0DNH3   K7IVA1   A8CW67   A0A224XWA4   R4V102   D6WA30   R4G2V0   A0A1B0GKL0   A0A067R2B1   A0A0M8ZUT5   A0A2S2PRX8   C4WT00   E0VGF9   A0A1L8EFI3   A0A1L8EFN0   A0A1L8EHV5   A0A1L8EHQ6   A0A1Y1JXP9   A0A1I8PI26   A0A158NNJ1   T1PLJ3   A0A2U9QWK6   E2AZU0   A0A1Y1LIV1   A0A1A9VVI6   A0A171A632   A0A1A9ZZM0   Q2PYZ6   D9J145   A8D916   E2BZV8   A0A2S2Q4D1   F4WEY7   A0A0J7KV83   A0A3B0K562   A0A0L0BQI9   A0A1A9XTB5   A0A1B0BEY3   A0A151JQP9   B4PLV6   B4M6F2   A0A195C2H5   A0A151X800   A0A1B6F9S5   A0A1A9WRP3   Q6XHY9   A0A1W4W2Z2   Q7KRU8   A0A0R1E7B7   B4HZQ0   J3JWN8   B4R1L1   D1GLP2   E9IP36   I5AMX3   B4GNN4   B3P598   A0A310SMX9  

EC Number

1.16.3.1

Pubmed

19121390    11317331    11903622    26354079    22651552    23622113    + More
22118469    10560139    28756777    29403074    28410430    16023793    16235258    29036914    17760985    12761873    24508170    30249741    28648823    20075255    18194529    18362917    19820115    24845553    20566863    28004739    21347285    25315136    20798317    16907828    20353571    20542901    18824242    21719571    26108605    17994087    17550304    18057021    14525923    9266686    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22516182    23537049    19851452    21282665    15632085   

EMBL

DQ483055    DQ443196    ABF19823.1    ABF51285.1    DQ898220    ABI79326.1    + More
BABH01037774    AF142340    AAG41120.1    AY032659    AAK39636.1    GBRD01002699    JAG63122.1    KQ460130    KPJ17532.1    AK401292    KQ459249    BAM17914.1    KPJ02301.1    AK402386    BAM19008.1    GDQN01010973    GDQN01007740    GDQN01002701    JAT80081.1    JAT83314.1    JAT88353.1    ODYU01002146    SOQ39261.1    GDQN01008981    GDQN01008620    GDQN01007416    JAT82073.1    JAT82434.1    JAT83638.1    GAIX01012046    JAA80514.1    AGBW02007657    OWR54798.1    AF161707    AF161708    AAD50238.1    AAD50239.1    EF032585    ABM92425.1    NWSH01001214    PCG72098.1    KZ149901    PZC78540.1    PYGN01000291    PSN49158.1    FX985453    BAX07466.1    AY829743    AAV91357.1    AY297687    AAP57194.1    MF872898    ATD12167.1    GAHY01001558    JAA75952.1    KY653080    ATU47274.1    KY031131    ATU82882.1    GALX01002672    JAB65794.1    NEVH01019998    PNF21994.1    GEMB01001462    JAS01694.1    KT748792    AMK48573.1    EU045340    ABV44737.1    KC571840    AGM32339.1    GFDF01007640    JAV06444.1    AF509878    AAM44043.1    GFTR01003623    JAW12803.1    ACPB03013966    ACPB03014189    GDJX01014586    JAT53350.1    GBYB01013955    JAG83722.1    KK107796    QOIP01000013    EZA47606.1    RLU15413.1    NNAY01000096    OXU31019.1    AJVK01017562    AAZX01001186    AAZX01014257    EU124589    ABV60307.1    GFTR01003624    JAW12802.1    KC632508    AGM32322.1    KQ971312    EEZ98069.1    GAHY01002271    JAA75239.1    AJWK01029076    KK852805    KDR16113.1    KQ435834    KOX71580.1    GGMR01018977    MBY31596.1    ABLF02025519    AK340403    BAH71020.1    DS235142    EEB12465.1    GFDG01001424    JAV17375.1    GFDG01001426    JAV17373.1    GFDG01000551    JAV18248.1    GFDG01000552    JAV18247.1    GEZM01098351    JAV53913.1    ADTU01002748    ADTU01002749    KA646648    KA649501    KA649579    AFP64208.1    MH324410    AWU66528.1    GL444277    EFN61069.1    GEZM01056148    JAV72821.1    GEMB01001461    JAS01695.1    CCAG010023089    DQ294233    EZ423489    ABC48949.1    ADD19765.1    HM243541    ADI87389.1    EU144232    ABV68875.1    GL451708    EFN78735.1    GGMS01003258    MBY72461.1    GL888112    EGI67258.1    LBMM01002940    KMQ94159.1    OUUW01000005    SPP80081.1    JRES01001520    KNC22276.1    JXJN01013116    KQ978627    KYN29565.1    CM000160    EDW99093.1    CH940652    EDW59228.1    KRF78760.1    KQ978344    KYM94790.1    KQ982431    KYQ56440.1    GECZ01022767    JAS47002.1    AY232043    AAR10066.1    U91524    AE014297    AY061831    Y15629    AAB70121.1    AAF57034.1    AAL27642.1    CAA75724.1    KRK04654.1    CH480819    EDW53507.1    APGK01028086    APGK01028087    BT127656    KB740686    KB632335    AEE62618.1    ENN79505.1    ERL92809.1    CM000364    EDX14999.1    FN395057    CAZ04924.1    GL764423    EFZ17668.1    CM000070    EIM52308.1    CH479186    EDW39360.1    CH954182    EDV53081.1    KQ761834    OAD56690.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000218220    UP000245037    + More
UP000192223    UP000235965    UP000015103    UP000053097    UP000279307    UP000215335    UP000092462    UP000002358    UP000007266    UP000092461    UP000027135    UP000053105    UP000007819    UP000009046    UP000095300    UP000005205    UP000095301    UP000000311    UP000078200    UP000092445    UP000092444    UP000008237    UP000007755    UP000036403    UP000268350    UP000037069    UP000092443    UP000092460    UP000078492    UP000002282    UP000008792    UP000078542    UP000075809    UP000091820    UP000192221    UP000000803    UP000001292    UP000019118    UP000030742    UP000000304    UP000001819    UP000008744    UP000008711   

PRIDE

Q1HQ56    Q06FJ5    H9JGX1    Q7KRU8   

Pfam

PF00210   Ferritin

Interpro

IPR008331   Ferritin_DPS_dom        + More
IPR001519   Ferritin       
IPR012347   Ferritin-like       
IPR009040   Ferritin-like_diiron       
IPR009078   Ferritin-like_SF       
IPR014034   Ferritin_CS       

SUPFAM

SSF47240   SSF47240       

Gene 3D

1.20.1260.10    

ProteinModelPortal

Q1HQ56   Q06FJ5   H9JGX1   Q9GQW5   Q8WQX3   A0A0K8TC38   + More
A0A0N1IPY3   I4DJ24   I4DM68   A0A1E1W8M6   A0A2H1VER5   A0A1E1W9G2   S4NTX6   A0A212FM21   Q9TVR3   A9NJI5   A0A2A4JK48   A0A2W1C098   A0A2P8YY31   A0A1V1G5M1   Q5MGP3   Q7Z161   A0A1W4WWM1   A0A2D1AEE0   R4FL73   A0A2H4N0Q4   A0A2K8JSG7   V5GNT8   A0A2J7Q081   A0A171A5W7   A0A140DKV8   A8CAE8   R4UJT6   A0A1L8DJC8   Q8MUX0   A0A224XXB4   T1HTF0   T1HYY6   A0A1D1YFD4   A0A0C9RXN6   A0A026VVU9   A0A232FKJ7   A0A1B0DNH3   K7IVA1   A8CW67   A0A224XWA4   R4V102   D6WA30   R4G2V0   A0A1B0GKL0   A0A067R2B1   A0A0M8ZUT5   A0A2S2PRX8   C4WT00   E0VGF9   A0A1L8EFI3   A0A1L8EFN0   A0A1L8EHV5   A0A1L8EHQ6   A0A1Y1JXP9   A0A1I8PI26   A0A158NNJ1   T1PLJ3   A0A2U9QWK6   E2AZU0   A0A1Y1LIV1   A0A1A9VVI6   A0A171A632   A0A1A9ZZM0   Q2PYZ6   D9J145   A8D916   E2BZV8   A0A2S2Q4D1   F4WEY7   A0A0J7KV83   A0A3B0K562   A0A0L0BQI9   A0A1A9XTB5   A0A1B0BEY3   A0A151JQP9   B4PLV6   B4M6F2   A0A195C2H5   A0A151X800   A0A1B6F9S5   A0A1A9WRP3   Q6XHY9   A0A1W4W2Z2   Q7KRU8   A0A0R1E7B7   B4HZQ0   J3JWN8   B4R1L1   D1GLP2   E9IP36   I5AMX3   B4GNN4   B3P598   A0A310SMX9  

PDB

1Z6O     E-value=6.68518e-49,     Score=484

KEGG

732916    K00522 ferritin heavy chain [EC:1.16.3.2] | (RefSeq) ferritin

GO

GO:0006826   GO:0006879   GO:0005623   GO:0004322   GO:0008199   GO:0005794   GO:0098711   GO:0005737   GO:0006880   GO:0005506   GO:0008198   GO:0042802   GO:0008043   GO:1990461   GO:0009791   GO:0008283   GO:0005576   GO:0045169   GO:0009620   GO:0016021   GO:0005634   GO:0008270   GO:0003677   GO:0006101   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR11431  

SignalP

Position:   1 - 20,         Likelihood:  0.998758

 

 

Length:

164

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

11.16847

Exp number, first 60 AAs:

11.06668

Total prob of N-in:

0.31449

POSSIBLE N-term signal

sequence

outside

1  -  164

 

 

Pi

198.89602

Theta

152.72369

Tajima's D

1.284794

CLR

0.031518

CSRT

0.739963001849907

Interpretation

Uncertain