Gene

KWMTBOMO14599  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008780

Annotation

ferritin_precursor_[Bombyx_mori]

Location

Bomo_Chr24(-):11071294-11077253      View in EpiBrowser

Full name

Ferritin      

Location in the cell

Extracellular   Reliability : 3.463

CDS

ATGAAGGTGTATGCTCTCATCGTTGCCTGTCTGGCTCTGGGTGTGCTGGCCGAGGAAGACTCATGCTATCAGAACGTCGACCAAGGATGCAGACGGACTTTAAGTCTGCCGCACTGCAGCGCGTATTACGGCCAATTCAAGGACAACCACGTTGTAGCGAACGAACTGAAGGCATTAGCCTCACTGTATTTGAAACGTTCCTACCATTATCTCCTGTCGGCCTCCTACTTCAACAACTACCAGACGAACAGGGAAGGATTCGCGAAGCTCTTCAGGAAATTATCGGACGATTCGTGGGAGAAAACCATTGGTCTCATAAAGCACGTCACTAAGAGGGGTGGGAAGATGGACTTCTCGAGTCACACCACACTGAAAGGCGACAAGGGCAGCAACTACACCGTCGAGGTCGGCCACGAGATCGGAGCCCTGGCCAAAGCCTTGGACACGCAGAAGCAGCTTGCCGAGAGGATTTTCTTCATCCACAGGGAAGTCACTAAAAACAGCGACCTCCTCCACGATGCTGAGATCACTCAATACATCGAGGAGGAATTCGTGAGTCAGCAAGCCGATACGATTCGTAGCCTCGCGGGTCACACCTCGGACCTCAAGCGGTTCATAACCGAGAACAACGGGAAAGACTTGTCTCTCGCCGTGTACCTCTTCGACGAGTACCTCCAGAAGGTCGTCTAA

Protein

MKVYALIVACLALGVLAEEDSCYQNVDQGCRRTLSLPHCSAYYGQFKDNHVVANELKALASLYLKRSYHYLLSASYFNNYQTNREGFAKLFRKLSDDSWEKTIGLIKHVTKRGGKMDFSSHTTLKGDKGSNYTVEVGHEIGALAKALDTQKQLAERIFFIHREVTKNSDLLHDAEITQYIEEEFVSQQADTIRSLAGHTSDLKRFITENNGKDLSLAVYLFDEYLQKVV

Description

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

Catalytic Activity

4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O

Similarity

Belongs to the ferritin family.

Feature

chain  Ferritin

Uniprot

Q0PVM8   Q1HQ02   H9JGY3   A0A0N1PIQ5   I4DJC2   I4DMF4   + More
A0A2H1VEG9   Q9N2P3   A0A1E1WSJ0   A0A2A4JK12   Q8WSA5   A0A2A4JJJ1   A0A194Q9Y0   A0A0K8SIQ4   A9NJI6   Q52SA8   A0A194Q6T8   D5LPT0   Q9TVI4   A0A1V1G1K8   A0A2J7Q090   R4UMS8   A0A2H8U0S9   A0A1Y1MAF8   J9K3X9   A0A2S2ND95   D6WA31   A0A1D1XZM0   A0A2H4T362   A0A1Y1JX64   A0A2S2Q6G3   A0A067RBS6   K9UVP3   A0A077CZF7   A0A1W4X7G0   A0A0T6B5I0   R4WML0   A0A224XW27   A0A1B6GR05   A0A161MIU5   A0A1B6LI98   V5GLU6   A0A310SB21   A0A0N0BEA0   Q4PLJ6   R4G4L4   Q8MUW9   A0A2K8JML0   A0A1Y1K540   A0A1A9WRP4   A0A026VVE4   A0A2P8YY37   D1GLP3   E0W2V2   R4G347   A0A3L8D4Z0   Q8WS65   A0A1B6JHD0   E2BZV7   D3TRQ2   A0A1A9ZZM1   A0A171A643   A0A1A9VVI7   T1I6V1   A0A154P2J8   B4M6F3   A0A1A9XTB4   A0A1B0BEY4   A0A1L8EFT8   A0A2H4N1R0   A0A224XW38   N6UFU5   K7IVA0   J3JUC4   A0A1I8QEM1   A0A0Q9WV65   A0A1B6BX34   A0A232FKI6   B4NGU9   A0A1I8QEV5   T1P7M8   A0A1I8N0W6   A0A1W4VQW7   A0A0Q9X5F8   D9J146   F4MI35   A0A195C1N7   E9IP35   T1H8P8   A0A151JQP8   A0A151HZA6   B4JEP4   B4K9S0   A0A1L8EFK1   B3LZE8   A0A195FVK2   A0A0A1XPR2  

EC Number

1.16.3.1

Pubmed

19121390    26354079    22651552    8682313    12232875    15896348    + More
10560139    28410430    28004739    18362917    19820115    24845553    23691247    12761873    24508170    29403074    19851452    20566863    30249741    17098167    20353571    20798317    17994087    23537049    20075255    22516182    28648823    25315136    20542901    21569254    21282665    25830018   

EMBL

DQ683022    ABG76019.1    DQ443250    DQ683021    ABF51339.1    ABG76018.1    + More
BABH01037774    KQ460130    KPJ17531.1    AK401390    BAM18012.1    AK402472    BAM19094.1    ODYU01002146    SOQ39260.1    L47123    AAF44717.1    GDQN01001120    JAT89934.1    NWSH01001310    PCG71763.1    AF329683    AAL47694.1    PCG71764.1    KQ459249    KPJ02302.1    GBRD01013151    JAG52675.1    EF032586    ABM92426.1    AY970292    AAX94729.1    KQ459581    KPI99105.1    GU953220    ADF43204.1    AF161709    AF161710    AAD50240.1    AAD50241.1    FX985454    BAX07467.1    NEVH01019998    PNF21998.1    KC571845    KC571906    AGM32405.1    GFXV01007836    MBW19641.1    GEZM01039667    JAV81295.1    ABLF02025519    GGMR01002486    MBY15105.1    KQ971312    EEZ98578.1    GDJX01020100    JAT47836.1    MF774484    ATY70349.1    GEZM01098351    JAV53914.1    GGMS01004132    MBY73335.1    KK852805    KDR16114.1    JX865415    AFY99034.1    KJ872588    AIL26079.1    LJIG01009672    KRT82611.1    AK416881    BAN20096.1    GFTR01003746    JAW12680.1    GECZ01004986    JAS64783.1    GEMB01001460    JAS01696.1    GEBQ01016564    JAT23413.1    GALX01003427    JAB65039.1    KQ761834    OAD56689.1    KQ435834    KOX71581.1    DQ067275    AAY68366.1    ACPB03014189    GAHY01000671    JAA76839.1    AF509879    AAM44044.1    KY031130    ATU82881.1    GEZM01092605    JAV56524.1    KK107796    EZA47605.1    PYGN01000291    PSN49157.1    FN395057    CAZ04925.1    DS235879    EEB19958.1    GAHY01002006    JAA75504.1    QOIP01000013    RLU15296.1    CCAG010023089    AF368916    EZ423061    AAL65406.2    ADD19337.1    GECU01033751    GECU01029697    GECU01009000    JAS73955.1    JAS78009.1    JAS98706.1    GL451708    EFN78734.1    EZ424104    ADD20380.1    GEMB01001459    JAS01697.1    ACPB03022856    KQ434796    KZC05564.1    CH940652    EDW59229.1    JXJN01013116    GFDG01001314    JAV17485.1    KY653088    ATU47282.1    GFTR01003736    JAW12690.1    APGK01028087    APGK01028088    APGK01028089    APGK01028090    KB740686    KB632335    ENN79506.1    ERL92810.1    AAZX01001186    BT126837    AEE61799.1    CH964272    KRG00032.1    GEDC01031467    GEDC01024669    GEDC01018186    JAS05831.1    JAS12629.1    JAS19112.1    NNAY01000096    OXU31009.1    EDW84446.1    KA644611    AFP59240.1    KRG00033.1    HM243542    ADI87390.1    EZ617716    ADH94609.1    KQ978344    KYM94789.1    GL764423    EFZ17667.1    ACPB03013966    KQ978627    KYN29564.1    KQ976693    KYM77665.1    CH916369    EDV93175.1    CH933806    EDW14545.1    GFDG01001289    JAV17510.1    CH902617    EDV44127.1    KQ981268    KYN43889.1    GBXI01002083    GBXI01001729    JAD12209.1    JAD12563.1   

Proteomes

UP000005204    UP000053240    UP000218220    UP000053268    UP000235965    UP000007819    + More
UP000007266    UP000027135    UP000192223    UP000053105    UP000015103    UP000091820    UP000053097    UP000245037    UP000009046    UP000279307    UP000092444    UP000008237    UP000092445    UP000078200    UP000076502    UP000008792    UP000092443    UP000092460    UP000019118    UP000030742    UP000002358    UP000095300    UP000007798    UP000215335    UP000095301    UP000192221    UP000078542    UP000078492    UP000078540    UP000001070    UP000009192    UP000007801    UP000078541   

PRIDE

Q1HQ02    H9JGY3   

Pfam

PF00210   Ferritin        + More
PF00089   Trypsin

Interpro

IPR008331   Ferritin_DPS_dom        + More
IPR001519   Ferritin       
IPR012347   Ferritin-like       
IPR009040   Ferritin-like_diiron       
IPR009078   Ferritin-like_SF       
IPR009003   Peptidase_S1_PA       
IPR018114   TRYPSIN_HIS       
IPR001254   Trypsin_dom       
IPR014034   Ferritin_CS       

SUPFAM

SSF47240   SSF47240        + More
SSF50494   SSF50494       

Gene 3D

1.20.1260.10    

ProteinModelPortal

Q0PVM8   Q1HQ02   H9JGY3   A0A0N1PIQ5   I4DJC2   I4DMF4   + More
A0A2H1VEG9   Q9N2P3   A0A1E1WSJ0   A0A2A4JK12   Q8WSA5   A0A2A4JJJ1   A0A194Q9Y0   A0A0K8SIQ4   A9NJI6   Q52SA8   A0A194Q6T8   D5LPT0   Q9TVI4   A0A1V1G1K8   A0A2J7Q090   R4UMS8   A0A2H8U0S9   A0A1Y1MAF8   J9K3X9   A0A2S2ND95   D6WA31   A0A1D1XZM0   A0A2H4T362   A0A1Y1JX64   A0A2S2Q6G3   A0A067RBS6   K9UVP3   A0A077CZF7   A0A1W4X7G0   A0A0T6B5I0   R4WML0   A0A224XW27   A0A1B6GR05   A0A161MIU5   A0A1B6LI98   V5GLU6   A0A310SB21   A0A0N0BEA0   Q4PLJ6   R4G4L4   Q8MUW9   A0A2K8JML0   A0A1Y1K540   A0A1A9WRP4   A0A026VVE4   A0A2P8YY37   D1GLP3   E0W2V2   R4G347   A0A3L8D4Z0   Q8WS65   A0A1B6JHD0   E2BZV7   D3TRQ2   A0A1A9ZZM1   A0A171A643   A0A1A9VVI7   T1I6V1   A0A154P2J8   B4M6F3   A0A1A9XTB4   A0A1B0BEY4   A0A1L8EFT8   A0A2H4N1R0   A0A224XW38   N6UFU5   K7IVA0   J3JUC4   A0A1I8QEM1   A0A0Q9WV65   A0A1B6BX34   A0A232FKI6   B4NGU9   A0A1I8QEV5   T1P7M8   A0A1I8N0W6   A0A1W4VQW7   A0A0Q9X5F8   D9J146   F4MI35   A0A195C1N7   E9IP35   T1H8P8   A0A151JQP8   A0A151HZA6   B4JEP4   B4K9S0   A0A1L8EFK1   B3LZE8   A0A195FVK2   A0A0A1XPR2  

PDB

1Z6O     E-value=2.21444e-68,     Score=655

KEGG

732949    no KO assigned | (RefSeq) ferritin

GO

GO:0004322   GO:0008199   GO:0006879   GO:0005623   GO:0006826   GO:0004252   GO:0005737   GO:0005506   GO:0006880   GO:0010106   GO:0098711   GO:0005794   GO:0008043   GO:1990461   GO:0008198   GO:0042802   GO:0016021   GO:0046872   GO:0045475   GO:0005634   GO:0008270   GO:0003677   GO:0006101   GO:0003824   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR11431  

SignalP

Position:   1 - 17,         Likelihood:  0.999556

 

 

Length:

229

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04081

Exp number, first 60 AAs:

0.0391

Total prob of N-in:

0.08649

outside

1  -  229

 

 

Pi

162.379696

Theta

134.91037

Tajima's D

0.205525

CLR

152.316181

CSRT

0.426128693565322

Interpretation

Uncertain