Silkworm Genome Informatics Database

Gene

KWMTBOMO14559

Annotation

PREDICTED:_uncharacterized_protein_LOC106140354_[Amyelois_transitella]

Location

Bomo_Chr24(+):10217529-10218770 View in EpiBrowser

Full name

RNA-dependent RNA polymerase

Location in the cell

Cytoplasmic Reliability : 3.429

CDS

ATGAAGAGTAATGAAAGTACCCAAGGCTGGTTGGTCGACACCGGTGCAAGTGAACATATGTGTTTTCAGAGAAGTTTATTTTGTGATTTTGAAGAGTATGAATCTTACCAGTTAATAATAGTTGGTGATGGCAGAGAACTACAGGTTATTGGTAAAGGAAAAGTGATCCTTAAAGCTTTTGATGGACAGGAATGCATTGATACCACTCTGCATAATGTGTTGTATGTTGCCAAACTGACAATTAATTTATTTGCTATTTGTATATTTCCTAAACAAAAGAGTGAAGTCCCTGACAAGATTAAAGAGTTTATAAATTTGGCTGAACAAGATACCGATGCAAAGGTAAAAGTTGTAAGAACTGATAATGGAAGTGAATTTATTAATGCAACAGTTAAAGAGTTATTTAAGGAAAAAGGCATAAGACACCAGACATCTACAGCATATACACCGGAACAAAATGGTAAAATAGAAAGAGATAATAGAACAGTCGTGGAGGCAGCTGGAGCTATGATAATAAGTGCAAAATTACCCAAGGAGCTGTGGGCTGAAGCAGTCAACACTGCAACTGCAAGAGCATTTATGGGTGAATATTTGAATGTCTCGCTGTGA

Protein

MKSNESTQGWLVDTGASEHMCFQRSLFCDFEEYESYQLIIVGDGRELQVIGKGKVILKAFDGQECIDTTLHNVLYVAKLTINLFAICIFPKQKSEVPDKIKEFINLAEQDTDAKVKVVRTDNGSEFINATVKELFKEKGIRHQTSTAYTPEQNGKIERDNRTVVEAAGAMIISAKLPKELWAEAVNTATARAFMGEYLNVSL

Description

Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).

Catalytic Activity

a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)

Similarity

Belongs to the RdRP family.

Uniprot

X1WSV9 A0A1R3GTE9 A0A1S2Z2F8 Q8S479 A0A2G2W0U9 Q7XBD2 + More
A0A061EWN5 A0A2G3BH31 A0A3P6E929 Q9AY98 A5C4B5 Q10I04 A0A061F7Q8 A0A2N9HM03 A0A1P8YYH4 A0A2P4XY06 Q8W0X4

EC Number

2.7.7.48

Pubmed

26259924 15466289 15466290 15489523 29089032 14701910 + More
23731509 16109971 28228439 28186564

EMBL

ABLF02008716 ABLF02008720 ABLF02045773 ABLF02046985 ABLF02060789 AWWV01013476 + More
OMO61385.1 AF466202 AAL75483.1 MLFT02000009 PHT38854.1 AY325816 AAP94592.1 CM001883 EOY08837.1 MCIT02000010 PHU05794.1 LR031875 VDD32801.1 AC084319 AAG59661.1 AM481880 CAN75289.1 DP000009 ABF97186.1 CM001885 EOY12702.1 OIVN01003693 SPD12988.1 KX852318 AQA29556.1 NCKW01007026 POM70436.1 AF464738 AAL66759.1

Proteomes

UP000007819 UP000188268 UP000087171 UP000224567 UP000026915 UP000224522 + More

Pfam

PF00665   rve        + More
PF13961   DUF4219
PF07727   RVT_2
PF14244   Retrotran_gag_3
PF03732   Retrotrans_gag
PF00098   zf-CCHC
PF04755   PAP_fibrillin
PF05183   RdRP
PF00931   NB-ARC
PF07714   Pkinase_Tyr

Interpro

IPR001584   Integrase_cat-core        + More
IPR039537   Retrotran_Ty1/copia-like
IPR012337   RNaseH-like_sf
IPR036875   Znf_CCHC_sf
IPR001878   Znf_CCHC
IPR036397   RNaseH_sf
IPR013103   RVT_2
IPR025314   DUF4219
IPR005162   Retrotrans_gag_dom
IPR029472   Copia-like_N
IPR036291   NAD(P)-bd_dom_sf
IPR039633   PAP
IPR006843   PAP/fibrillin_dom
IPR007855   RNA-dep_RNA_pol_euk-typ
IPR003593   AAA+_ATPase
IPR001245   Ser-Thr/Tyr_kinase_cat_dom
IPR027417   P-loop_NTPase
IPR011009   Kinase-like_dom_sf
IPR002182   NB-ARC

SUPFAM

SSF53098   SSF53098        + More
SSF57756   SSF57756
SSF51735   SSF51735
SSF56112   SSF56112
SSF52540   SSF52540

Gene 3D

3.30.420.10

ProteinModelPortal

X1WSV9 A0A1R3GTE9 A0A1S2Z2F8 Q8S479 A0A2G2W0U9 Q7XBD2 + More
A0A061EWN5 A0A2G3BH31 A0A3P6E929 Q9AY98 A5C4B5 Q10I04 A0A061F7Q8 A0A2N9HM03 A0A1P8YYH4 A0A2P4XY06 Q8W0X4

PDB

5UOQ E-value=1.25385e-05, Score=113

KEGG

NA

GO

GO:0008270 GO:0003676 GO:0000943 GO:0015074 GO:0003723 GO:0031047 GO:0003968 GO:0004672 GO:0043531 GO:0003964 GO:0005524 GO:0006085 GO:0006101 GO:0003824 GO:0008152 GO:0016491 GO:0015930

PANTHER

PTHR11439 PTHR31906 PTHR23079

Length:

202

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.62172

Exp number, first 60 AAs:

0

Total prob of N-in:

0.17816

outside

1 - 202

Pi

253.542647

Theta

173.875028

Tajima's D

1.385012

CLR

0

CSRT

0.762461876906155

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics