SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO14542  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA014404
Annotation
clip_domain_serine_protease_11_precursor_[Bombyx_mori]
Location in the cell
Extracellular   Reliability : 3.365
 

Sequence

CDS
ATGTTTCTTCAGATGTACAAGCTTCTATTCATCGGCTTTCTCGCGTCGGCGTGCGCGCAGAACATGGACACCGGGGATCTGGAGTCGATCATTAATCAGATCTTCACATCAGCGAAGCCCCCGACGCAATTGCAGCCGGTCACGCAGCCTAGTGTCGCTGATAGGGCTCCATCGACCCTGGTGCCTGGCGTCTCTACGAACGATGACCTTTCGTGCCAGACCTCCGACGGCCAAGAAGGGGAGTGCGTCAACTATTACTTGTGCAATGCGGCCAATAACACCATTATCACTGACGGAACAAACGTCATCGATATAAGAGTCGGCAGTGGCCCGTGTTCATCGTACATCGACGTCTGCTGTCTGGCTCCCGACCAGAGACCGCCAACAGATCCCATCACGCCCAGGCCGGAGACCCTGCCAATGAACCAGGGCTGCGGCTGGCGGAACCCTGACGGCGTTGCCTTCCGGACCACGGGCGACGTGGACGGCGAGACCAAGTTCGGAGAGTTCCCCTGGATGGTCGCCATCCTCAAGGTTGAACCAGTCGATGACAACGAGCCCGAAGGACAGAAGCTGAACGTTTACGTAGGGGGAGGCTCGCTGATCCATCCGAACGTGGTGCTCACGGCCGCTCACTACGTTGCCGCCGCCAAGGAACTGAAGATCAGAGCCGGCGAATGGGACACGCAGAACACGAAGGAGATATATCCGTATCAAGACAGGACAGTCAAGGAAATCGTGATACACAAGGACTTCAATAAGGGGAACCTGTTCTACGACATAGCTCTGCTGTTCCTCGAGACTCCATTGGATTCAGCCCCGAACGTGGGAGTGGCGTGTCTCCCACCGGCCAGGGAGCGCGCCCCCGCCGGCGTCAGGTGCTTCGCCACCGGCTGGGGGAAGGACAAGTTCGGGAAGGAAGGTAGATACCAGGTCATCATGAAGAAGGTGGACGTGCCGGTCGTGGACCGGAACACCTGCCAGAGCCAGTTGAGGAGGACGCGGCTGGGGCGGTTCTTCCAGTTGCACTCGACGTTCATGTGCGCGGGGGGGGAGCCCGACAAGGACACCTGCCGGGGGGACGGGGGGTCGCCCCTCGTGTGCCCCATAGACTATGAGAAGAATCGCTATGTCCAATACGGCATCGTAGCCTGGGGCATAGGCTGCGGAGAGGACGGCACTCCAGGAGTTTACGTGGACGTCTCGAACCTGAGGACCTGGATCGACGACAAGGTCGCCGGCAAGGGATACGATACTAGATCCTACGAGCCCTAG
Protein
MFLQMYKLLFIGFLASACAQNMDTGDLESIINQIFTSAKPPTQLQPVTQPSVADRAPSTLVPGVSTNDDLSCQTSDGQEGECVNYYLCNAANNTIITDGTNVIDIRVGSGPCSSYIDVCCLAPDQRPPTDPITPRPETLPMNQGCGWRNPDGVAFRTTGDVDGETKFGEFPWMVAILKVEPVDDNEPEGQKLNVYVGGGSLIHPNVVLTAAHYVAAAKELKIRAGEWDTQNTKEIYPYQDRTVKEIVIHKDFNKGNLFYDIALLFLETPLDSAPNVGVACLPPARERAPAGVRCFATGWGKDKFGKEGRYQVIMKKVDVPVVDRNTCQSQLRRTRLGRFFQLHSTFMCAGGEPDKDTCRGDGGSPLVCPIDYEKNRYVQYGIVAWGIGCGEDGTPGVYVDVSNLRTWIDDKVAGKGYDTRSYEP

Summary

Similarity
Belongs to the peptidase S1 family.
EMBL
AF513368    AB436165    AAN77090.1    BAG70412.1    BABH01041359    BABH01041360    + More
BABH01041361    BABH01041362    GQ222378    ACS92763.1    EU770391    ACI32835.1    NWSH01000512    PCG75933.1    KZ150319    PZC71430.1    KQ459348    KPJ01304.1    AK402486    BAM19108.1    AK401279    BAM17901.1    KQ459805    KPJ19884.1    FJ882067    ACZ68116.1    AY829844    AAV91458.1    AF518767    AAM69352.2    AY672800    AAV91027.1    RSAL01000281    RVE43040.1    AGBW02009431    OWR50839.1    NWSH01001072    PCG72769.1    FX985353    BAX07366.1    FX985352    BAX07365.1    GFDF01005356    JAV08728.1    KQ971314    EEZ99181.1    AJ400904    CAC12696.1    ODYU01001277    SOQ37275.1    KK853313    KDR08623.1    KPJ01302.1    PYGN01001938    PSN32091.1    DS235201    EEB13231.1    FX985366    BAX07379.1    ODYU01007576    SOQ50463.1    NNAY01002322    OXU21553.1    AAZX01008083    GFDF01005366    JAV08718.1    APGK01030057    KB740754    ENN79053.1    KX346577    ASN76824.1    KB632375    ERL93883.1    BT127757    AEE62719.1    GFDF01005367    JAV08717.1    GEDC01016436    JAS20862.1    GBYB01004128    JAG73895.1    GEZM01077542    JAV63282.1    KQ435753    KOX76091.1    NEVH01012082    PNF30937.1    CH933807    EDW13537.1    KRG03846.1    JR049796    AEY61083.1    GANO01003790    JAB56081.1    KQ434829    KZC07692.1    CH940649    EDW64546.1    CVRI01000070    CRL07164.1    CP012523    ALC39186.1    KK107293    EZA53191.1    GL888002    EGI69195.1    KZ288370    PBC26753.1    KQ981855    KYN34949.1    GL446181    EFN88365.1    KQ414590    KOC70333.1    MH261257    AYA71582.1    KQ979039    KYN23318.1    KQ976423    KYM88738.1    ADTU01000905    CH479180    EDW28409.1    OUUW01000006    SPP81651.1    PNF30938.1    GBXI01016415    JAC97876.1    GECZ01003846    JAS65923.1    CH916372    EDV99444.1    KPJ19883.1    GECZ01006603    JAS63166.1    GAKP01011334    JAC47618.1    KQ978002    KYM98233.1    AJWK01024105    AJWK01024106    AJWK01024107    GFDL01011778    JAV23267.1    DS232931    EDS26833.1    KQ434938    KZC12025.1    JN215469    AEX33291.1    CH477246    EAT46191.1    GAMC01007476    JAB99079.1    GAMC01007477    JAB99078.1    GGFJ01005632    MBW54773.1    GGFJ01005633    MBW54774.1    GL761812    EFZ22761.1    GDHF01002678    JAI49636.1    CH964265    EDW83475.2    CM000157    EDW88785.1    GDHF01026236    GDHF01017251    GDHF01011785    JAI26078.1    JAI35063.1    JAI40529.1    GBHO01024948    JAG18656.1    CH954177    EDV58501.1    GALA01001132    JAA93720.1    AXCN02001108    GGFK01008174    MBW41495.1    GANO01003789    JAB56082.1    ADMH02001629    ETN61717.1    LJIG01002238    KRT84702.1    GEMB01003263    JAR99950.1    CH480818    EDW52396.1    KZC12174.1    AE014134    BT044284    AAF52904.1    ACH92349.1   
Pfam
PF00089   Trypsin        + More
PF18322   CLIP_1
Interpro
IPR001254   Trypsin_dom        + More
IPR041515   PPAF-2_Clip       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR018114   TRYPSIN_HIS       
SUPFAM
SSF50494   SSF50494       
PDB
2B9L     E-value=3.60674e-82,     Score=777

Ontologies

Topology

SignalP
Position:   1 - 19,         Likelihood:  0.978403
 
 
Length:
424
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.04082
Exp number, first 60 AAs:
0.00724
Total prob of N-in:
0.00187
outside
1  -  424
 
 

Population Genetic Test Statistics

Pi
250.104975
Theta
166.733274
Tajima's D
1.774624
CLR
0.051228
CSRT
0.84240787960602
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
24402669 YVQIIYDAVNTEDYAK 96.55 1e-13
25044914 FFPYYVSNVIAGIDSDGK 95.24 7e-10
24402669 FFNWHR 95.24 7e-10
28467696 FFQGADER 95.24 7e-10
29197581 EIYPYQDR 95.24 7e-10
20822545 AGEWDTQNTKEIYPYQDR 100.00 2e-09
20822545 IRAGEWDTQNTK 100.00 3e-07
20822545 DTCRGDGGSPLVCPIDYEK 100.00 7e-07
31223520 VEPVDDNEPEGQK 100.00 3e-04
31223520 FGEFPWMVAILK 100.00 0.032
24093152 VEPEVGEVINKK 100.00 0.032
24402669 VEPNTIPIIR 100.00 0.032
28467696 VEPEVGEVINKK 100.00 0.032
29197581 VDVPVVDR 100.00 0.032
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