Gene

KWMTBOMO14530  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA014398

Annotation

PREDICTED:_eukaryotic_peptide_chain_release_factor_subunit_1_[Amyelois_transitella]

Location

Bomo_Chr24(+):9646466-9669005      View in EpiBrowser

Full name

Eukaryotic peptide chain release factor subunit 1      

Location in the cell

Cytoplasmic   Reliability : 3.269

CDS

ATGTCTGAAGAATCGTCGGCCGATCGAAATGTCGAAATATGGAAGATAAAGAAACTTATAAAGAGTTTGGAAATGGCCAGAGGAAATGGAACATCGATGATATCCCTGATCATTCCACCTAAGGATCAAATCTCGAGAGTATCAAAGATGTTGGCTGATGAATTTGGTACAGCTTCTAATATCAAGTCACGTGTGAATCGTCTCTCAGTGCTTGGCGCAATTACTTCTGTACAGCACCGACTCAAGCTGTATACTAAAGTGCCACCAAACGGCCTAGTTATATACTGTGGTACTATCGTGACAGAAGAAGGTAAAGAGAAGAAAGTGAACATTGATTTTGAGCCGTTCAAGCCTATCAACACATCTCTTTATCTCTGCGACAACAAGTTCCACACCGAGGCTCTAACAGCACTGCTGGCTGATGATAACAAGTTTGGTTTCATTGTTATGGATGGTAACGGTGCATTATTCGGTACCCTTCAAGGAAACACTAGAGAGGTACTCCACAAGTTTACTGTCGATCTCCCTAAGAAGCACGGTCGCGGTGGTCAGTCAGCGCTGCGTTTCGCTCGTCTCCGTATGGAGAAACGTCACAATTACGTCCGTAAGGTTGCCGAGGTAGCCACCCAGCTGTTCATCAGTGCTGACCGGCCGAACGTTGCTGGCCTCATCCTTGCGGGTTCTGCTGATTTTAAGACTGAACTGTCCCAGTCCGATATGTTTGATCCGCGTCTCCAAGCCAAGATCATAAAACTGGTGGACGTATCATATGGAGGCGAAAACGGTTTCAATCAGGCTATAGAGCTGGCTGCGGAATCCTTGCAGAATGTCAAGTTTATACAGGAGAAGAAACTAATTGGACGCTACTTTGATGAGATCTCACAGGACACAGGAAAGTATTGCTTCGGTGTCGATGATACACTGCGCGCTCTCGAACTCGGATCCGTCGAGACGTTGATCTGCTGGGAGAACCTCGACATACAAAGATACGTATTGAAGTCGCATGCCACCAACCAGGAAACAATTCTCCACCTGACGCCTGAACAAGAGAAGGACAAATCACATTTCACCGACAAAGAGAGCGGAGTGGAGCTGGAGCTTGTGGAGTGCCAGCCGCTGTTGGAGTGGCTGGCCAATAACTACAAGTCGTTTGGTGCCACCTTAGAGATCATCACGGACAAGAGCCAGGAGGGAAGCCAGTTCGTTCGCGGCTTCGGAGGGATCGGCGGTCTCCTCCGTTACAAAGTGGACTTCCAATCGATGCAGCTCGACGACGAGGAAATCGACAATCTATACGACATCGACGACTATTAG

Protein

MSEESSADRNVEIWKIKKLIKSLEMARGNGTSMISLIIPPKDQISRVSKMLADEFGTASNIKSRVNRLSVLGAITSVQHRLKLYTKVPPNGLVIYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLADDNKFGFIVMDGNGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAEVATQLFISADRPNVAGLILAGSADFKTELSQSDMFDPRLQAKIIKLVDVSYGGENGFNQAIELAAESLQNVKFIQEKKLIGRYFDEISQDTGKYCFGVDDTLRALELGSVETLICWENLDIQRYVLKSHATNQETILHLTPEQEKDKSHFTDKESGVELELVECQPLLEWLANNYKSFGATLEIITDKSQEGSQFVRGFGGIGGLLRYKVDFQSMQLDDEEIDNLYDIDDY

Description

Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.

Subunit

Heterodimer of two subunits, one of which binds GTP.

Similarity

Belongs to the eukaryotic release factor 1 family.

Keywords

Complete proteome   Cytoplasm   Phosphoprotein   Protein biosynthesis   Reference proteome  

Feature

chain  Eukaryotic peptide chain release factor subunit 1

Uniprot

I4DNA6   A0A3S2M1H9   S4P221   A0A1E1WMS9   Q2F5R7   A0A194R8P0   + More
A0A194PWL8   A0A2A4JDH0   A0A232EU20   K7IXJ8   E2A5U8   A0A026WXX0   A0A2A3EM31   A0A154PQ89   A0A195DKK3   F4WBG5   A0A195B3F9   A0A195FTR3   A0A158P126   A0A2R7VYF7   A0A0A9Y8A5   A0A224XCL0   A0A2J7RMF9   A0A0T6B7W7   R4WRS9   A0A0P4VUH7   T1HR39   A0A067QX62   A0A069DZ03   A0A0A1WNW3   A0A1Y1MM32   A0A1B6DYM6   A0A1B6HQR2   V5I9K4   J9JYP0   A0A2S2R218   A0A2S2N8H0   A0A0K8TNX1   W8BUE3   N6TX29   A0A1B6MKS2   A0A1B6FV35   A0A158P127   H9JXY0   A0A151WWM3   A0A1W4W6E5   A0A0J9RYL4   B4KY20   B3NIJ7   B3M975   B4PFA6   A0A0C9R7G1   A0A034W963   A0A1B0ARB1   B4GR19   A0A1A9ZFX9   D1Z373   D3TRE7   Q9VPH7   A0A0M5J8C5   B4MLK5   Q16P70   B4LGF2   A0A0K8V2R2   A0A3B0KLP6   B4IA85   A0A182W7Y2   A0A023ES91   A0A2W1BDZ4   D6WCG2   B4QRX2   A0A1Q3F6M8   B0WFV9   A0A084VJJ4   T1D417   A0A182JB29   B4IWX5   A0A182ML94   A0A182QFY0   A0A182NP75   Q7PLZ0   A0A182RS95   A0A182KE76   A0A182FLW9   A0A182PWU4   A0A182YDX7   A0A2M3ZFR8   A0A2J7RMG1   A0A2M4A4E1   W5JVA6   T1PDF9   A0A182GW91   A0A0R3P821   A0A1Q3FWQ6   A0A336KGH0   A0A034WAN3   A0A0K8S805   A0A1W4VUF2   A0A0Q9XCM5   M9PD27  

Pubmed

22651552    23622113    26354079    28648823    20075255    20798317    + More
24508170    30249741    21719571    21347285    25401762    26823975    23691247    27129103    24845553    26334808    25830018    28004739    26369729    24495485    23537049    19121390    22936249    17994087    18057021    17550304    25348373    20353571    10731132    12537572    12537569    18327897    17510324    24945155    28756777    18362917    19820115    24438588    24330624    12364791    14747013    17210077    25244985    20920257    23761445    25315136    26483478    15632085    12537568    12537573    12537574    16110336    17569856    17569867   

EMBL

AK402804    BAM19396.1    RSAL01000072    RVE49045.1    GAIX01012215    JAA80345.1    + More
GDQN01009915    GDQN01002893    JAT81139.1    JAT88161.1    DQ311356    ABD36300.1    KQ460500    KPJ14203.1    KQ459589    KPI97717.1    NWSH01001904    PCG69728.1    NNAY01002185    OXU21853.1    AAZX01004642    GL437061    EFN71190.1    KK107064    QOIP01000008    EZA60920.1    RLU19693.1    KZ288212    PBC32815.1    KQ435034    KZC14052.1    KQ980765    KYN13367.1    GL888063    EGI68444.1    KQ976641    KYM78805.1    KQ981272    KYN43853.1    ADTU01006100    ADTU01006101    KK854169    PTY12492.1    GBHO01015205    GBRD01007346    GDHC01012256    GDHC01003745    JAG28399.1    JAG58475.1    JAQ06373.1    JAQ14884.1    GFTR01006260    JAW10166.1    NEVH01002556    PNF42027.1    LJIG01009252    KRT83452.1    AK417407    BAN20622.1    GDKW01000912    JAI55683.1    ACPB03022348    KK853149    KDR10692.1    GBGD01001490    JAC87399.1    GBXI01013961    JAD00331.1    GEZM01027433    JAV86743.1    GEDC01006518    JAS30780.1    GECU01030690    JAS77016.1    GALX01002780    JAB65686.1    ABLF02032620    GGMS01014179    MBY83382.1    GGMR01000826    MBY13445.1    GDAI01001516    JAI16087.1    GAMC01013811    JAB92744.1    APGK01051689    APGK01051690    APGK01051691    APGK01051692    APGK01051693    KB741201    KB632375    ENN72951.1    ERL93875.1    GEBQ01003463    JAT36514.1    GECZ01022892    GECZ01015711    GECZ01002578    JAS46877.1    JAS54058.1    JAS67191.1    BABH01040929    BABH01040930    BABH01040931    KQ982691    KYQ52216.1    CM002912    KMZ00747.1    KMZ00748.1    KMZ00749.1    KMZ00752.1    KMZ00753.1    KMZ00754.1    KMZ00755.1    CH933809    EDW18722.1    KRG06336.1    CH954178    EDV52493.1    KQS44302.1    KQS44303.1    KQS44304.1    CH902618    EDV40059.1    KPU78351.1    KPU78352.1    CM000159    EDW95192.1    KRK02283.1    KRK02284.1    KRK02285.1    KRK02286.1    KRK02287.1    GBYB01003935    GBYB01003936    JAG73702.1    JAG73703.1    GAKP01008095    GAKP01008093    GAKP01008092    JAC50857.1    JXJN01002301    CH479188    EDW40204.1    BT120009    BT120010    ACZ94121.1    ACZ94122.1    CCAG010010279    EZ423999    ADD20275.1    AE014296    AY069511    CP012525    ALC44161.1    CH963847    EDW72861.1    KRF97644.1    CH477792    EAT36164.1    CH940647    EDW70481.1    GDHF01019216    JAI33098.1    OUUW01000009    SPP84738.1    CH480826    EDW44198.1    GAPW01001491    GAPW01001490    JAC12108.1    KZ150381    PZC71090.1    KQ971311    EEZ98876.1    CM000363    EDX11218.1    GFDL01011821    JAV23224.1    DS231921    EDS26494.1    ATLV01013640    KE524876    KFB38138.1    GALA01001138    JAA93714.1    AXCP01007712    CH916366    EDV97376.1    AXCM01001493    AXCN02002423    AAAB01008981    EAA14616.2    GGFM01006519    MBW27270.1    PNF42025.1    GGFK01002342    MBW35663.1    ADMH02000009    ETN68111.1    KA646160    AFP60789.1    JXUM01092887    JXUM01092888    KQ564017    KXJ72934.1    CH379069    KRT07680.1    GFDL01003005    JAV32040.1    UFQS01000344    UFQT01000344    SSX03032.1    SSX23397.1    GAKP01008094    JAC50858.1    GBRD01016415    JAG49411.1    KRG06335.1    AGB94797.1   

Proteomes

UP000283053    UP000053240    UP000053268    UP000218220    UP000215335    UP000002358    + More
UP000000311    UP000053097    UP000279307    UP000242457    UP000076502    UP000078492    UP000007755    UP000078540    UP000078541    UP000005205    UP000235965    UP000015103    UP000027135    UP000007819    UP000019118    UP000030742    UP000005204    UP000075809    UP000192221    UP000009192    UP000008711    UP000007801    UP000002282    UP000092460    UP000008744    UP000092445    UP000092444    UP000000803    UP000092553    UP000007798    UP000008820    UP000008792    UP000268350    UP000001292    UP000075920    UP000007266    UP000000304    UP000002320    UP000030765    UP000075880    UP000001070    UP000075883    UP000075886    UP000075884    UP000007062    UP000075900    UP000075881    UP000069272    UP000075885    UP000076408    UP000000673    UP000095301    UP000069940    UP000249989    UP000001819   

PRIDE

Q2F5R7    H9JXY0    D1Z373    Q9VPH7    M9PD27   

Pfam

PF03465   eRF1_3        + More
PF03463   eRF1_1
PF03464   eRF1_2

Interpro

IPR029064   L30e-like        + More
IPR005141   eRF1_2       
IPR005140   eRF1_1_Pelota       
IPR024049   Release_factor_eRF1/aRF1_N       
IPR042226   eFR1_2_sf       
IPR004403   Peptide_chain-rel_eRF1/aRF1       
IPR005142   eRF1_3       

SUPFAM

SSF55481   SSF55481        + More
SSF55315   SSF55315       

Gene 3D

3.30.1330.30     3.30.420.60     3.30.960.10    

ProteinModelPortal

I4DNA6   A0A3S2M1H9   S4P221   A0A1E1WMS9   Q2F5R7   A0A194R8P0   + More
A0A194PWL8   A0A2A4JDH0   A0A232EU20   K7IXJ8   E2A5U8   A0A026WXX0   A0A2A3EM31   A0A154PQ89   A0A195DKK3   F4WBG5   A0A195B3F9   A0A195FTR3   A0A158P126   A0A2R7VYF7   A0A0A9Y8A5   A0A224XCL0   A0A2J7RMF9   A0A0T6B7W7   R4WRS9   A0A0P4VUH7   T1HR39   A0A067QX62   A0A069DZ03   A0A0A1WNW3   A0A1Y1MM32   A0A1B6DYM6   A0A1B6HQR2   V5I9K4   J9JYP0   A0A2S2R218   A0A2S2N8H0   A0A0K8TNX1   W8BUE3   N6TX29   A0A1B6MKS2   A0A1B6FV35   A0A158P127   H9JXY0   A0A151WWM3   A0A1W4W6E5   A0A0J9RYL4   B4KY20   B3NIJ7   B3M975   B4PFA6   A0A0C9R7G1   A0A034W963   A0A1B0ARB1   B4GR19   A0A1A9ZFX9   D1Z373   D3TRE7   Q9VPH7   A0A0M5J8C5   B4MLK5   Q16P70   B4LGF2   A0A0K8V2R2   A0A3B0KLP6   B4IA85   A0A182W7Y2   A0A023ES91   A0A2W1BDZ4   D6WCG2   B4QRX2   A0A1Q3F6M8   B0WFV9   A0A084VJJ4   T1D417   A0A182JB29   B4IWX5   A0A182ML94   A0A182QFY0   A0A182NP75   Q7PLZ0   A0A182RS95   A0A182KE76   A0A182FLW9   A0A182PWU4   A0A182YDX7   A0A2M3ZFR8   A0A2J7RMG1   A0A2M4A4E1   W5JVA6   T1PDF9   A0A182GW91   A0A0R3P821   A0A1Q3FWQ6   A0A336KGH0   A0A034WAN3   A0A0K8S805   A0A1W4VUF2   A0A0Q9XCM5   M9PD27  

PDB

3E1Y     E-value=0,     Score=1937

KEGG

101737911    K03265 peptide chain release factor subunit 1 | (RefSeq) eukaryotic peptide chain release factor sub

PATHWAY

03015    mRNA surveillance pathway - Bombyx mori (domestic silkworm)

GO

GO:0003747   GO:0005737   GO:0006415   GO:0018444   GO:0016149   GO:0002184   GO:1990825   GO:0005829   GO:0008270   GO:0015074   GO:0005524   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

PANTHER

PTHR10113  

Subcellular location

Cytoplasm  

Length:

437

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0121

Exp number, first 60 AAs:

0.00372

Total prob of N-in:

0.00907

outside

1  -  437

 

 

Pi

227.112708

Theta

191.676967

Tajima's D

0.917262

CLR

0.320861

CSRT

0.63746812659367

Interpretation

Uncertain