Gene

KWMTBOMO14490  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000158

Annotation

ecdysone_oxidase_[Bombyx_mori]

Location

Bomo_Chr24(+):7890710-7895443      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.028 Extracellular   Reliability : 1.161 PlasmaMembrane   Reliability : 1.027

CDS

ATGGCAGACGCGGCAACAGCAGTTATGGCTCTGGCGTATTTGTTCCAGTGGCCTCCCCAAGCAATAGTGCAGGATGGTGACACCTTTGATTTCGTCGTTGTCGGATCGGGATGTGGAGCTATTGTGGCTGATAGATTGTCGGAAAACAGTTCAGTGCGAGTTCTTTTGATTGAAGCAGGAACATACCCGTCGAACGAATCTATTATGCCTGGAACTTTTCCTTTACTCCAAAATTCATACGAGGACTGGAACGAGACATCGATCCCGGAGAGCACAACGAAACACCAAAAGATCGGCGCGTACAAGCTGTCGACGGGAAAAGCCTTGGGCGGAGGCAGCACTATCAATCACCTACTCCATCTCCGAGGAGACAAGGACGACTTCGATACTTGGGCGTCCTACCTTGGAGACGACTCTTGGTCATCCGCAAACGTCCGTAAGTACTTCAAGAAATCGGAGAACATGCTAGACGCAGATATAATGGCCAGTCACGCCGACTACCACGGGACTGAAGGTCCAGTGATGGTATCAAGGCAGCCCGACGACGCCACGCACAACTTATTGAAGGCTTTTAGCGATATCGGAGTGCCAACGGTGATTGACTTGAACGCGGATGACAACGTTGGATGTGCAGAGGCTTCATACATCATAGGTGACGGTGTGCGACAGAGCACTGCTTACGCGTACCTAAATAAAAAAACTAGAGATAATCTGTACGTGCTTACCGAAACATTAGCAGAAAAAATCATCATCGAAAACGACATAGCTAAAGGTGTTATCTTGCGGCTAGCAAGCGGCAAGAAAATCAATGTTTACGCTAGCAAAGAAGTTATTATATCGGCCGGATCATTCAACAGTCCAAAAATACTAATGCTCTCTGGGATCGGGCCAGCTGATCACCTGAAAAGCATGGGCATTGACGTCATCAAAGATCTACCTGTGGGCCAGGGAATGCAGGACCACAATGCACTTTTCCTAGTCAACAAATTGGAAGAATCAACGGCGACTTCGGAAACATTACCATTAACAAAATTTCCGTTCCCTATTCTATTGGCTAGCGTCAACCTAGATGATTCTAAAAGCTACGCCGACTATCTGCTTATTGGACTTGTATTCGCCCAGGACAAAGGCTACACCGATGTTACTTGTTCGACTCTCTTTAGCTTCACCGACGAAATATGCTCGAACTTTAGCGAAAGCGTCGCCGGTAGGAACCAATTCATTTCATTAATAGGCACATCCCAACCAAAATCCAGGGGCTACGTGCAGCTAAAAAGTTCAGATCCAGATGACAAACTAGTTATATCAGAATCATTTTATTCTGATCCCGAAGATTTTACTAACATGCTGAAGTATCTAACTCATTTTTTAACTATTTACAATTCCGCTTATTTCCAAGATATCAAAGCGGAAATAGCTGATCCCGGCTTGGAAGAATGCGGTGAGATGGACGTCAGTAGTGAGGATTATTGGAAGTGTTACATCAAGTCCATGACCGTCCACCTATTCCATTACTCCGGTACATGTGCCATGGGCAGTGTGGTGGACAGTAAAATGAAAGTGTACGGTATAGATAACCTCCGGGTTGTCGATGTGAGCACCATGCCTTTTATCGTCAGAGCCAATACCTTGGCGGCTGGCATAATGATGGCGGAAAAGATAAGTGACGACATTAAAAATGAATATTCCCTTTGA

Protein

MADAATAVMALAYLFQWPPQAIVQDGDTFDFVVVGSGCGAIVADRLSENSSVRVLLIEAGTYPSNESIMPGTFPLLQNSYEDWNETSIPESTTKHQKIGAYKLSTGKALGGGSTINHLLHLRGDKDDFDTWASYLGDDSWSSANVRKYFKKSENMLDADIMASHADYHGTEGPVMVSRQPDDATHNLLKAFSDIGVPTVIDLNADDNVGCAEASYIIGDGVRQSTAYAYLNKKTRDNLYVLTETLAEKIIIENDIAKGVILRLASGKKINVYASKEVIISAGSFNSPKILMLSGIGPADHLKSMGIDVIKDLPVGQGMQDHNALFLVNKLEESTATSETLPLTKFPFPILLASVNLDDSKSYADYLLIGLVFAQDKGYTDVTCSTLFSFTDEICSNFSESVAGRNQFISLIGTSQPKSRGYVQLKSSDPDDKLVISESFYSDPEDFTNMLKYLTHFLTIYNSAYFQDIKAEIADPGLEECGEMDVSSEDYWKCYIKSMTVHLFHYSGTCAMGSVVDSKMKVYGIDNLRVVDVSTMPFIVRANTLAAGIMMAEKISDDIKNEYSL

Cofactor

FAD

Similarity

Belongs to the GMC oxidoreductase family.

Uniprot

C7EPE2   H9IS42   A0A0L7L247   A0A2H1WPH8   A0A2H1WQ34   A0A0N1PIV1   + More
A0A3S2LRK7   A0A2W1BQ09   A0A2A4IZ69   A0A2H1VZZ7   A0A2A4JE08   A0A3S2N607   A0A2W1BU23   A0A0L7LL99   A0A2A4JYC1   A0A0L7KN60   A0A2H1W7M4   A0A212FMS7   A0A2W1BEK9   D0ABA6   A0A2H1VP10   A0A2A4IZE5   A0A2A4JWF9   A0A2H1W0I8   A0A2W1BRA5   A0A2H1VCU6   A0A2H1V0S8   A0A212F6I0   A0A2W1BPR7   A0A2A4JF29   A0A0L7LUK3   A0A2H1VB55   A0A2W1BIV7   A0A212F6I8   A0A194QAM1   A0A2W1BM44   A0A2A4J139   A0A0N1IPT1   A0A194QAR0   A0A2A4JUI0   H9J869   A0A0L7LPB4   A0A0N0PDR9   A0A2H1W336   A0A194QGE4   A0A2A4JSK9   B8Y866   A0A2H1VYA6   A0A2H1VCV1   A0A2A4K9G4   A0A2W1B6G7   A0A194PPA0   A0A2A4JQV7   A0A2H1W3T3   A0A2W1BFD2   A0A194QNE6   A0A0N1I9P3   H9JLP6   A0A2H1WHG3   A0A2W1BHP2   A0A2A4K5W1   H9J868   A0A2H1VDA1   A0A2H1WHH0   A0A2W1BCG7   H9JLQ9   A0A0L7LQD8   A0A0N0PE61   A0A2W1BWE7   A0A2H1WZ72   A0A194R898   A0A291P0W5   A0A2H1V4R2   A0A2H1VDD9   A0A194PXZ3   A0A2A4K6C3   A0A0L7KY98   A0A212EII3   A0A2H1WZL6   H9JRF5   Q95NZ0   A0A3S2M5K0   A0A2H1VJT7   A0A2W1BIM1   A0A151WNR9   A0A0L7L0I7   A0A1B0D7C5   A0A212F947   A0A2A4IYS9   A0A2W1B5P9   A0A212FF54   A0A0L7L6H5   A0A0P4ZUK9   A0A1Z2RRI5   V9IE09   A0A087ZVX2   H9JTY8   A0A194QAU5   A0A2H1V9N6   A0A0N1IJ07  

Pubmed

19121390    26227816    26354079    28756777    22118469    28986331    + More
11373299    28605547   

EMBL

BABH01024320    GQ285072    ACT66690.2    BABH01024325    JTDY01003559    KOB69344.1    + More
ODYU01010073    SOQ54917.1    ODYU01010216    SOQ55185.1    KQ460044    KPJ18290.1    RSAL01000341    RVE42399.1    KZ150085    PZC73783.1    NWSH01004322    PCG65227.1    ODYU01005459    SOQ46343.1    NWSH01001885    PCG69794.1    RVE42398.1    KZ149963    PZC76280.1    JTDY01000758    KOB75991.1    NWSH01000427    PCG76483.1    JTDY01008771    KOB64409.1    ODYU01006844    SOQ49058.1    AGBW02007651    OWR55045.1    KZ150336    PZC71326.1    FP102341    CBH09301.1    ODYU01003587    SOQ42538.1    NWSH01004349    PCG65195.1    NWSH01000445    PCG76355.1    SOQ46342.1    KZ149986    PZC75677.1    ODYU01001603    SOQ38054.1    ODYU01000155    SOQ34448.1    AGBW02010007    OWR49345.1    PZC76281.1    NWSH01001625    PCG70657.1    JTDY01000066    KOB79079.1    ODYU01001607    SOQ38065.1    KZ150015    PZC74989.1    OWR49347.1    KQ459232    KPJ02522.1    PZC73780.1    NWSH01004424    PCG65132.1    KPJ18289.1    KPJ02519.1    NWSH01000559    PCG75661.1    BABH01039860    BABH01039861    JTDY01000418    KOB77282.1    KPJ18288.1    ODYU01006017    SOQ47491.1    KPJ02521.1    NWSH01000760    PCG74382.1    FJ493468    ACL36977.1    ODYU01005196    SOQ45815.1    SOQ38064.1    NWSH01000039    PCG80370.1    KZ150274    PZC71662.1    KQ459603    KPI92960.1    PCG74381.1    SOQ47492.1    PZC73782.1    KQ461194    KPJ06879.1    KPJ18287.1    BABH01005285    ODYU01008704    SOQ52509.1    PZC73781.1    NWSH01000095    PCG79621.1    BABH01039855    BABH01039856    ODYU01001935    SOQ38829.1    SOQ52508.1    KZ150303    PZC71524.1    BABH01005224    BABH01005225    BABH01005226    JTDY01000335    KOB77647.1    KPJ18306.1    KZ149916    PZC77944.1    ODYU01012146    SOQ58297.1    KQ460627    KPJ13480.1    MF687606    ATJ44532.1    ODYU01000650    SOQ35789.1    ODYU01001944    SOQ38845.1    KQ459585    KPI98211.1    PCG79619.1    JTDY01004415    KOB68187.1    AGBW02014643    OWR41285.1    ODYU01012241    SOQ58442.1    BABH01016356    AY035784    AY035785    AAK56551.1    AAK56552.1    RSAL01000028    RVE51877.1    ODYU01002782    SOQ40702.1    PZC71523.1    KQ982905    KYQ49514.1    JTDY01003781    KOB69013.1    AJVK01026844    AJVK01026845    AJVK01026846    AGBW02009643    OWR50262.1    NWSH01004668    PCG64789.1    KZ150306    PZC71499.1    AGBW02008849    OWR52369.1    JTDY01002689    KOB70914.1    GDIP01222028    GDIP01209432    GDIP01052298    GDIP01045705    JAJ13970.1    KY938814    ASA46455.1    JR040861    AEY59320.1    BABH01003799    KPJ02554.1    ODYU01001405    SOQ37539.1    KPJ18321.1   

Proteomes

UP000005204    UP000037510    UP000053240    UP000283053    UP000218220    UP000007151    + More
UP000053268    UP000075809    UP000092462    UP000005203   

PRIDE

C7EPE2    H9IS42    H9J869    H9JLP6    H9J868    H9JLQ9    + More
H9JRF5    H9JTY8   

Pfam

PF00732   GMC_oxred_N        + More
PF05199   GMC_oxred_C

Interpro

IPR036188   FAD/NAD-bd_sf        + More
IPR000172   GMC_OxRdtase_N       
IPR012132   GMC_OxRdtase       
IPR007867   GMC_OxRtase_C       
IPR027424   Glucose_Oxidase_domain_2       

SUPFAM

SSF51905   SSF51905       

Gene 3D

3.50.50.60     4.10.450.10    

ProteinModelPortal

C7EPE2   H9IS42   A0A0L7L247   A0A2H1WPH8   A0A2H1WQ34   A0A0N1PIV1   + More
A0A3S2LRK7   A0A2W1BQ09   A0A2A4IZ69   A0A2H1VZZ7   A0A2A4JE08   A0A3S2N607   A0A2W1BU23   A0A0L7LL99   A0A2A4JYC1   A0A0L7KN60   A0A2H1W7M4   A0A212FMS7   A0A2W1BEK9   D0ABA6   A0A2H1VP10   A0A2A4IZE5   A0A2A4JWF9   A0A2H1W0I8   A0A2W1BRA5   A0A2H1VCU6   A0A2H1V0S8   A0A212F6I0   A0A2W1BPR7   A0A2A4JF29   A0A0L7LUK3   A0A2H1VB55   A0A2W1BIV7   A0A212F6I8   A0A194QAM1   A0A2W1BM44   A0A2A4J139   A0A0N1IPT1   A0A194QAR0   A0A2A4JUI0   H9J869   A0A0L7LPB4   A0A0N0PDR9   A0A2H1W336   A0A194QGE4   A0A2A4JSK9   B8Y866   A0A2H1VYA6   A0A2H1VCV1   A0A2A4K9G4   A0A2W1B6G7   A0A194PPA0   A0A2A4JQV7   A0A2H1W3T3   A0A2W1BFD2   A0A194QNE6   A0A0N1I9P3   H9JLP6   A0A2H1WHG3   A0A2W1BHP2   A0A2A4K5W1   H9J868   A0A2H1VDA1   A0A2H1WHH0   A0A2W1BCG7   H9JLQ9   A0A0L7LQD8   A0A0N0PE61   A0A2W1BWE7   A0A2H1WZ72   A0A194R898   A0A291P0W5   A0A2H1V4R2   A0A2H1VDD9   A0A194PXZ3   A0A2A4K6C3   A0A0L7KY98   A0A212EII3   A0A2H1WZL6   H9JRF5   Q95NZ0   A0A3S2M5K0   A0A2H1VJT7   A0A2W1BIM1   A0A151WNR9   A0A0L7L0I7   A0A1B0D7C5   A0A212F947   A0A2A4IYS9   A0A2W1B5P9   A0A212FF54   A0A0L7L6H5   A0A0P4ZUK9   A0A1Z2RRI5   V9IE09   A0A087ZVX2   H9JTY8   A0A194QAU5   A0A2H1V9N6   A0A0N1IJ07  

PDB

4YNU     E-value=1.88616e-46,     Score=470

KEGG

100302629    no KO assigned | (RefSeq) ecdysone oxidase

GO

GO:0016614   GO:0050660   GO:0016021   GO:0047875   GO:0016491   GO:0043565   GO:0005634   GO:0005524   GO:0005507   GO:0004713   GO:0015930   GO:0055114  

Length:

564

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.1045

Exp number, first 60 AAs:

0.04218

Total prob of N-in:

0.00477

outside

1  -  564

 

 

Pi

257.028791

Theta

174.440252

Tajima's D

1.356059

CLR

0.000011

CSRT

0.755562221888906

Interpretation

Possibly Positive selection