SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO14464
Annotation
PREDICTED:_ribosomal_protein_S6_kinase_alpha-5_isoform_X1_[Amyelois_transitella]
Full name
Non-specific serine/threonine protein kinase      
Location in the cell
Nuclear   Reliability : 3.946
 

Sequence

CDS
ATGTTAAAACAGGCTGTAGACTGGTGGTCGGTCGGCGTGCTGACCTACGAACTCCTGACCGGTGCCTCGCCGTTCACCGTCGAAGGCGAGAAAAATACACAGCACGAGATCACGAAGCGAATCGTTCGATGCAGTTATCCCCTACCTCCTGACGTCAGCCCCGAGGTTCAAGACTTTATTAGAAAATTATTAGTAAAAGATCCACGTCGGAGACTCGGAGGCGGCGAGGGTGACGCCGAAGAACTGAAGAGGCACTCCTTTTTCCAGAATTTGAATTGGGAGGCTGTGGCGAGACGCGAGGTTCCAGCGCCGTTCGTGCCGCAGTTGTCGCACGCGGCTGACACTTGCAACTTCGCGGATGAGTTCACGCGGATGCCGCCCACAGACTCGCCAGCCCAGGCTCCCAAACACAGCGACAAGCTATTCATGGGATACTCATACGTAGCTCCGAGTATATTGGTGTCGGAGAACATAATATCGGATCAGATATGGATGCAGGCGACCGGACAGAAAACCGAGAAGCTCAAAGGATGGACGCCCAAGGATTCCCCGTTCTTCCAAAAGTACGCCGTAGATTTGAGCGTGCCGCTGCTCGGCGACGGTTCGTACTCGGTGTGTAGGAAGTGCATCCACCGGCAGAGCGGCAAGGAGTACGCAGTCAAGATAATATCGACGCAAAAGAAAGATGTCAAACAAGAGATAGAGTTGCTGAAGGCCTGTCAGGGTTGTCCGTACATCGTAACGCTGCACGAAGTCATCGAGGATTCCGCGTTCACGTACATAGTGACGGAGCTGGTGAGCGGCGGCGAGCTGTGGGCGCGCGGGGCGGGCGCGGTGCCGGAGCGGGCGGCGCGCGGCCTGCTGGCCCAGCTGGCGCTGGCCGTGCGACACATGCACGCCGCGCGCACCGTGCACCGCGACCTCAAGCCAGAGAACATCCTGCTGACGAGCTCGCGGCTGGGCGACGCCCGCGTGAAGGTGGTGGACTTTGGATTCGCGCGCCGCATGCCGCCTCCAGACGAGCGCGCGCGCATGATGACTCCTTGCTTCAGCCTGCCGTACGCGGCGCCCGAGGTGCTCGCCCGCGCCCGCAGCGCCGCCGCGCCCGGCTACGGCCCGCAGTGCGACGCCTGGAGCCTCGGGGTCGTCTTCTACTGCATGCTGTGCGGCCGGGCTCCCTTCCAACCGACCTCCAGGAAGGAGCCGATAACGGCATACATGGACAGGATCCGGGCAGGAAACTTTACTATGGAAGGTCCGCAGTGGGACAAGATCTCGAGTGAGAGTAAACGCATCATAACCGGCTTACTGTCGGTCGAGCCGTCTCACCGGATGACCATCGACGAGCTGCTGGCCGACTTGGGAGTCAACACCGAAGAATCTGTCTTCAAATTATCCGACATGACCAAGGCGGACCTGTACAAACGCCGGAACAAGAACAAACCGCGCAAGTCCAGCTCCGAGCCCGGGCCATCCGGGGACCAGGACGGCGAGGCCTCGCTCATCGAGACTATCAACAGCCTCAAGCACAGGACGGACCGGAGCTCGATCGAGGACGACGTGGCGCTCATCCGGGCCAACACCCAGGACACGCCCGTGCACGACACCGCCGAGCCCAACTTCGAGGACGTGCCCCCAGTCAAGCCGGTCGAGAAGACCTACGCCAAGACCAGGTCCAAGCTGGACGACTACATCTACATCGAGAGCCATAAAGGTCTGGACGGCACCCAGGTCGCCTTCCCGAAAGTGCGAGCGAAGAAGTCCAAGGACTCCCCCGTGCCGCGCAAGAGGAGAAAAGTCGACGCGCCAGAGGCCAACGAGAGGCAATTGCGCAGTCGCGGCAAGAGAAGCACCCCCGCCACTCCCGTGGTTGAGAAGCGAGGCAAAGCCGACGGTAGAGTCACCAAGGAGTCGATAGAGAACGAAAAAACGGTCCGCGTCACTCGCAAGAGGAAATACGAGGAGATAACCAAGCCGGTGCTCAGGGAGAAGGGGCAGAACGGACGCGCCACGAGGCAAGCCAGCGAACGCAAAACGATCAAAGCGAAGAAAAAGGAAACTTTGACCTTGAATCAACAGGAAGATCAGATGCGCATGACGAGGTCCAGGAAGCGACGGCTGGAGGTCAGCCTCTCGCCTTCGGAAGTGAAGAGCATCGTGCCGGCGTTCTCGTTCGAGTCAGAGCGCCGCGTGGACTCCGTCGAGAGCACTAAATCCATCAAGAGCAGTACCAAAGCGAAATCTCGCAGGAACGCGAACGGCGCGAGCAAGGCCAAAAAGACGCCCGTCAGGTCGACGAGATCGCGCGGGAACAGACGGTGA
Protein
MLKQAVDWWSVGVLTYELLTGASPFTVEGEKNTQHEITKRIVRCSYPLPPDVSPEVQDFIRKLLVKDPRRRLGGGEGDAEELKRHSFFQNLNWEAVARREVPAPFVPQLSHAADTCNFADEFTRMPPTDSPAQAPKHSDKLFMGYSYVAPSILVSENIISDQIWMQATGQKTEKLKGWTPKDSPFFQKYAVDLSVPLLGDGSYSVCRKCIHRQSGKEYAVKIISTQKKDVKQEIELLKACQGCPYIVTLHEVIEDSAFTYIVTELVSGGELWARGAGAVPERAARGLLAQLALAVRHMHAARTVHRDLKPENILLTSSRLGDARVKVVDFGFARRMPPPDERARMMTPCFSLPYAAPEVLARARSAAAPGYGPQCDAWSLGVVFYCMLCGRAPFQPTSRKEPITAYMDRIRAGNFTMEGPQWDKISSESKRIITGLLSVEPSHRMTIDELLADLGVNTEESVFKLSDMTKADLYKRRNKNKPRKSSSEPGPSGDQDGEASLIETINSLKHRTDRSSIEDDVALIRANTQDTPVHDTAEPNFEDVPPVKPVEKTYAKTRSKLDDYIYIESHKGLDGTQVAFPKVRAKKSKDSPVPRKRRKVDAPEANERQLRSRGKRSTPATPVVEKRGKADGRVTKESIENEKTVRVTRKRKYEEITKPVLREKGQNGRATRQASERKTIKAKKKETLTLNQQEDQMRMTRSRKRRLEVSLSPSEVKSIVPAFSFESERRVDSVESTKSIKSSTKAKSRRNANGASKAKKTPVRSTRSRGNRR

Summary

Catalytic Activity
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]
EC Number
2.7.11.1
Pfam
PF00433   Pkinase_C        + More
PF00069   Pkinase
Interpro
IPR000719   Prot_kinase_dom        + More
IPR017892   Pkinase_C       
IPR000961   AGC-kinase_C       
IPR017441   Protein_kinase_ATP_BS       
IPR011009   Kinase-like_dom_sf       
IPR008271   Ser/Thr_kinase_AS       
IPR016239   Ribosomal_S6_kinase_II       
SUPFAM
SSF56112   SSF56112       
PDB
3KN6     E-value=1.80868e-60,     Score=592

Ontologies

Topology

Length:
773
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.17819
Exp number, first 60 AAs:
0.15817
Total prob of N-in:
0.00833
outside
1  -  773
 
 

Population Genetic Test Statistics

Pi
239.943485
Theta
174.070201
Tajima's D
1.064276
CLR
0.177129
CSRT
0.685615719214039
Interpretation
Uncertain
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