Gene

KWMTBOMO14421

Pre Gene Modal

BGIBMGA000124

Annotation

PREDICTED:_EF-hand_calcium-binding_domain-containing_protein_2_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr24(+):5734314-5736060      View in EpiBrowser

Full name

Dynein regulatory complex protein 8      

Alternative Name

EF-hand calcium-binding domain-containing protein 2

Location in the cell

Cytoplasmic   Reliability : 3.389

CDS

ATGGCAAGAAAAGAGGAACCTAAAATTCAACCAAACAATGATTTGGAGAAAAAAATAATTGAAGCTTTCGAAGTATTTGACCATTCTGGGAAGCAAGTCGTAGATGTAAGGGAAATAGGAACAATTCTTCGATCTTTGGGTTGCTGTCCAACTGAAGCCGAGATACAAGAGGTGATTTTAGCAACGGAAAACAAAGAAGCAACTGGAAACGTTCCGTTAACGAACTTTTTACCTTACATGTGTAAAGTCATGATAGAACATAGGTTTTATCCGGCGAGCGCTGAAATGCTGTTGGCTGCATTCAGATATTTTGACACGGAGGGACGTGGGTACCTCACTAAAGAGAGGTTCGCCAAGCTTATGATGGAAGAAGGAGAGTCATTTACGCAGGTACCTTAA

Protein

MARKEEPKIQPNNDLEKKIIEAFEVFDHSGKQVVDVREIGTILRSLGCCPTEAEIQEVILATENKEATGNVPLTNFLPYMCKVMIEHRFYPASAEMLLAAFRYFDTEGRGYLTKERFAKLMMEEGESFTQVP

Description

Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.

Subunit

Component of the nexin-dynein regulatory complex (N-DRC).

Similarity

Belongs to the DRC8 family.

Keywords

Cell projection   Cilium   Complete proteome   Cytoplasm   Cytoskeleton   Flagellum   Reference proteome   Repeat  

Feature

chain  Dynein regulatory complex protein 8

Uniprot

A0A3S2N9C8   A0A194QHH1   A0A2A4JSQ9   A0A2H1VJQ6   A0A212F8P5   D6WH45   + More
A0A0M3QUX1   B3MGT4   A0A0J9RH42   B4PAP9   B3NK69   A1ZBR3   B4GD84   A0A1W4VHM7   A8E6X0   A0A3B0J6Q3   B4KS17   B4MRV9   A0A2P8Z455   B4HPT8   B4JWF3   A0A1I8MRZ8   Q28YE0   A0A1Q3FUP3   A0A0L0CPC9   A0A182MM57   A0A182JAA1   A0A182YKV5   B4LPP9   A0A2J7RLC0   Q16GX0   A0A182WLM8   A0A084WL26   A0A182QRT5   A0A1A9VM93   Q7Q5W0   A0A182RDU5   A0A182KNW4   A0A182U726   A0A182I1A3   A0A1I8PMU1   A0A1A9ZCA3   W5JLS7   A0A182GBD7   A0A182K4J1   W8BCC1   N6U4A9   A0A1B0G5B7   A0A3Q0JAC1   A0A182NK12   A0A1B0CDA8   A0A0A1XCU9   A0A023EH73   A0A182V125   A0A182SZ13   A0A1A9YE55   A0A0A1WJ41   A0A1B0BC06   A0A1A9WWL3   M3XJ66   A0A151MH48   A0A0K8VSB6   A0A034WNZ0   V4AE55   A0A250YAS9   A0A0K8WIT6   A0A1B6K811   A0A0L8HTZ7   K7FCT5   F6WW69   A0A1L8G862   C3YGP7   F6Z713   A0A2Y9QTF4   A0A2Y9QZK8   A0A1S3F8H6   E0VFP3   A0A023EGL3   A0A2T7NW80   M7BJW6   G3SU53   H2YP25   V9LEB1   A0A2K6FMX8   H2XXB3   A0A1W3JEA3   A0A3Q7SEL7   Q9CQ46   V8P3K0   A0A2U3YYA9   R7T5W8   A0A2K6KHL6   A0A2K5X544   A0A2K5YJS7   A0A2I3N7Q6   A0A2K6NM89   A0A2K5HH94   F6VRD9  

Pubmed

26354079    22118469    18362917    19820115    17994087    22936249    + More
17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    29403074    25315136    15632085    26108605    25244985    17510324    24438588    12364791    14747013    17210077    20966253    20920257    23761445    26483478    24495485    23537049    25830018    24945155    9215903    22293439    25348373    23254933    28087693    17381049    20431018    27762356    18563158    20566863    23624526    24402279    12481130    15114417    16141072    15489334    21183079    24297900    25362486    17431167   

EMBL

RSAL01000179    RVE44978.1    KQ458859    KPJ04869.1    NWSH01000747    PCG74432.1    + More
ODYU01002937    SOQ41063.1    AGBW02009695    OWR50100.1    KQ971330    EEZ99756.1    CP012524    ALC41373.1    CH902619    EDV36842.1    CM002911    KMY95212.1    CM000158    EDW91440.2    CH954179    EDV55268.2    AE013599    KX531997    AAF57508.2    ANY27807.1    CH479181    EDW32579.1    BT030912    BT030969    ABV82294.1    ABV82351.1    OUUW01000001    SPP75512.1    CH933808    EDW10453.1    CH963850    EDW74848.1    PYGN01000204    PSN51278.1    CH480816    EDW48656.1    CH916375    EDV98291.1    CM000071    EAL26025.3    GFDL01003839    JAV31206.1    JRES01000204    KNC33294.1    AXCM01005227    CH940648    EDW60287.1    NEVH01002690    PNF41628.1    CH478229    EAT33493.1    ATLV01024175    KE525350    KFB50920.1    AXCN02000495    AAAB01008960    EAA11234.3    APCN01000048    ADMH02000773    ETN65086.1    JXUM01052658    KQ561744    KXJ77661.1    GAMC01015740    GAMC01015739    GAMC01015738    GAMC01015737    JAB90816.1    APGK01050095    APGK01050096    KB741165    KB632353    ENN73427.1    ERL93334.1    CCAG010011641    AJWK01007629    GBXI01005522    JAD08770.1    GAPW01005373    JAC08225.1    GBXI01015606    JAC98685.1    JXJN01011752    AFYH01043540    AFYH01043541    AFYH01043542    AFYH01043543    AKHW03006164    KYO23852.1    GDHF01010533    JAI41781.1    GAKP01003469    JAC55483.1    KB200294    ESP02304.1    GFFW01004088    JAV40700.1    GDHF01001564    JAI50750.1    GECU01000106    JAT07601.1    KQ417294    KOF92681.1    AGCU01167283    AGCU01167284    AGCU01167285    AGCU01167286    AGCU01167287    AAMC01001059    CM004474    OCT79985.1    GG666512    EEN60557.1    DS235123    EEB12199.1    GAPW01005653    JAC07945.1    PZQS01000008    PVD25433.1    KB522027    EMP37489.1    JW878192    AFP10709.1    EAAA01000432    EAAA01000433    AK010880    AK015157    AK018894    AK019663    AK019802    BC025062    AZIM01000889    ETE68915.1    AMQN01015156    KB311660    ELT88829.1    AQIA01000171    AQIA01000172    AQIA01000173    AQIA01000174    AQIA01000175    AQIA01000176    AQIA01000177    AHZZ02018064    AHZZ02018065    JSUE03003782    JSUE03003783    JSUE03003784    JSUE03003785    JSUE03003786    JSUE03003787    JSUE03003788   

Proteomes

UP000283053    UP000053268    UP000218220    UP000007151    UP000007266    UP000092553    + More
UP000007801    UP000002282    UP000008711    UP000000803    UP000008744    UP000192221    UP000268350    UP000009192    UP000007798    UP000245037    UP000001292    UP000001070    UP000095301    UP000001819    UP000037069    UP000075883    UP000075880    UP000076408    UP000008792    UP000235965    UP000008820    UP000075920    UP000030765    UP000075886    UP000078200    UP000007062    UP000075900    UP000075882    UP000075902    UP000075840    UP000095300    UP000092445    UP000000673    UP000069940    UP000249989    UP000075881    UP000019118    UP000030742    UP000092444    UP000079169    UP000075884    UP000092461    UP000075903    UP000075901    UP000092443    UP000092460    UP000091820    UP000008672    UP000050525    UP000030746    UP000053454    UP000007267    UP000008143    UP000186698    UP000001554    UP000248480    UP000081671    UP000009046    UP000245119    UP000031443    UP000007646    UP000007875    UP000233160    UP000008144    UP000286640    UP000000589    UP000245341    UP000014760    UP000233180    UP000233100    UP000233140    UP000028761    UP000233200    UP000233080    UP000006718   

PRIDE

A1ZBR3    Q9CQ46   

Pfam

PF08726   EFhand_Ca_insen        + More
PF13499   EF-hand_7
PF13405   EF-hand_6

Interpro

IPR002048   EF_hand_dom        + More
IPR011992   EF-hand-dom_pair       
IPR014837   EF-hand_Ca_insen       
IPR018247   EF_Hand_1_Ca_BS       

SUPFAM

SSF47473   SSF47473       

CDD

cd00051  EFh

ProteinModelPortal

A0A3S2N9C8   A0A194QHH1   A0A2A4JSQ9   A0A2H1VJQ6   A0A212F8P5   D6WH45   + More
A0A0M3QUX1   B3MGT4   A0A0J9RH42   B4PAP9   B3NK69   A1ZBR3   B4GD84   A0A1W4VHM7   A8E6X0   A0A3B0J6Q3   B4KS17   B4MRV9   A0A2P8Z455   B4HPT8   B4JWF3   A0A1I8MRZ8   Q28YE0   A0A1Q3FUP3   A0A0L0CPC9   A0A182MM57   A0A182JAA1   A0A182YKV5   B4LPP9   A0A2J7RLC0   Q16GX0   A0A182WLM8   A0A084WL26   A0A182QRT5   A0A1A9VM93   Q7Q5W0   A0A182RDU5   A0A182KNW4   A0A182U726   A0A182I1A3   A0A1I8PMU1   A0A1A9ZCA3   W5JLS7   A0A182GBD7   A0A182K4J1   W8BCC1   N6U4A9   A0A1B0G5B7   A0A3Q0JAC1   A0A182NK12   A0A1B0CDA8   A0A0A1XCU9   A0A023EH73   A0A182V125   A0A182SZ13   A0A1A9YE55   A0A0A1WJ41   A0A1B0BC06   A0A1A9WWL3   M3XJ66   A0A151MH48   A0A0K8VSB6   A0A034WNZ0   V4AE55   A0A250YAS9   A0A0K8WIT6   A0A1B6K811   A0A0L8HTZ7   K7FCT5   F6WW69   A0A1L8G862   C3YGP7   F6Z713   A0A2Y9QTF4   A0A2Y9QZK8   A0A1S3F8H6   E0VFP3   A0A023EGL3   A0A2T7NW80   M7BJW6   G3SU53   H2YP25   V9LEB1   A0A2K6FMX8   H2XXB3   A0A1W3JEA3   A0A3Q7SEL7   Q9CQ46   V8P3K0   A0A2U3YYA9   R7T5W8   A0A2K6KHL6   A0A2K5X544   A0A2K5YJS7   A0A2I3N7Q6   A0A2K6NM89   A0A2K5HH94   F6VRD9  

PDB

3SG2     E-value=1.58251e-13,     Score=178

KEGG

101744827    no KO assigned | (RefSeq) EF-hand calcium-binding domain-containing protein 2

GO

GO:0005509   GO:0016021   GO:0031514   GO:0005856   GO:0005737   GO:0016758   GO:0001784   GO:0006816   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

Subcellular location

  

Length:

132

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06667

Exp number, first 60 AAs:

0

Total prob of N-in:

0.37465

outside

1  -  132

 

 

Pi

158.912902

Theta

128.343341

Tajima's D

0.911246

CLR

56.170824

CSRT

0.643317834108295

Interpretation

Uncertain