Gene

KWMTBOMO14413

Pre Gene Modal

BGIBMGA000121

Annotation

PREDICTED:_GPI_mannosyltransferase_1_[Amyelois_transitella]

Location

Bomo_Chr24(+):5633954-5636745      View in EpiBrowser

Full name

GPI mannosyltransferase 1      

Alternative Name

GPI mannosyltransferase I
Phosphatidylinositol-glycan biosynthesis class M protein

Location in the cell

PlasmaMembrane   Reliability : 4.899

CDS

ATGGATCGCGTATCGAAATTTATCGATCTATCATTCGGGAACCACATTTGTATCGGTCTGACCGTGAGATTGGTGTTCATATTATACGGGAATATACACGATAGGTTTTCCGTAGTACCATACACTGATGTTGATTACAAAGTTTTCACGGACGCTGCGAGACATTTGGTGGAGGGTAACTCGCCCTATCTCCGGCACACTTACAGATACAGCCCTTTGATCGCGTATCTAATGATACCTAACATTATTGTCGGGAGAGAATTCGGAAAAATCCTTTTTTCCGTTTTCGATATATTTCTGGCGGCTGCCGTCAAATCTCTGGTCGAACGGCAATTGGGCGTCGCGAAATATGCTTCCGTCACAGCTAAATACTGTGCCTTATCTTGGCTCTACAATCCTCTAAGTATAGGCATCTCGACTCGAGGCAATGCCGATTCATTCCCGTGTTTCTTGATCGTCCTATCGATATACTTCCTTCAGTCGAACGTATTTAAAAATTCTATAACCAACATCGTCCTATCAGGCTTCTTTTTAGGTTCCGCAATACATCTACGCTTGTACCCGTTAGCCTTCACTTTCCCTATGTATCTATCTTTAGGAAAATATAAGATAAATCGTAATACCCCAATCAAAGAGGGTCTAGTTTCATTGCTACCCAACAAGAACCAAATGATTTTAGCCTTTAGCTGCGTTACAAGTCTTTTATTTATAACGTACGCTATGTACTTGAGATACGGTTACGAATTCTTATTCGAAACATATATTTATCATCTCCTCAGGAAAGACACTAGGCACAATTTCTCTATACTATTCTACTATACGTATTTAACGAAAGATCAGATGTCATTTGATATTGTCAAAATATTGGCACAGGTTTCCAAGTGCGTTCTACTTTTCCTGCTGAGTCTGAATTACGGTTGTGACCCAAAAACATTACCGTTCGCAATGTTCGCGCAAGCCGTCGTGCTGGTCGCTTATAACAGCGTCATGACATCACAGTACTTTATTTGGTTCCTCTCGTTATTACCATTGGTATTAAAAGACTTCAAAATGGAACCAGGTAAAATTGTTTACTTGGTTTTCCTCTGGATAGCGACTCAATGTGCTTGGTTGTTTTTCGCGTACCAATTAGAGTTCAAATGCAGGCAGGTTTTCATGTTGATCTGGTGTCAGAGCGTTATGTTCTATGGCAGTAATGTTTTTATACTGACGCAGCTTATAAAGTACTACCGCCCCGGCTACGCATTCGGGATAAACGAATCTGGCAAAGGAATAAAAGAGAAATGA

Protein

MDRVSKFIDLSFGNHICIGLTVRLVFILYGNIHDRFSVVPYTDVDYKVFTDAARHLVEGNSPYLRHTYRYSPLIAYLMIPNIIVGREFGKILFSVFDIFLAAAVKSLVERQLGVAKYASVTAKYCALSWLYNPLSIGISTRGNADSFPCFLIVLSIYFLQSNVFKNSITNIVLSGFFLGSAIHLRLYPLAFTFPMYLSLGKYKINRNTPIKEGLVSLLPNKNQMILAFSCVTSLLFITYAMYLRYGYEFLFETYIYHLLRKDTRHNFSILFYYTYLTKDQMSFDIVKILAQVSKCVLLFLLSLNYGCDPKTLPFAMFAQAVVLVAYNSVMTSQYFIWFLSLLPLVLKDFKMEPGKIVYLVFLWIATQCAWLFFAYQLEFKCRQVFMLIWCQSVMFYGSNVFILTQLIKYYRPGYAFGINESGKGIKEK

Description

Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (By similarity).

Similarity

Belongs to the PIGM family.

Keywords

Complete proteome   Endoplasmic reticulum   Glycosyltransferase   GPI-anchor biosynthesis   Membrane   Reference proteome   Transferase   Transmembrane   Transmembrane helix  

Feature

chain  GPI mannosyltransferase 1

Uniprot

H9IS94   A0A1E1W669   A0A194QH28   A0A0L7LJ24   A0A212FA37   A0A026W2R9   + More
A0A158NC27   A0A2J7R9A6   F4X8B0   A0A067QTY4   A0A1B6JC24   A0A1B6HQE1   A0A151IMB5   A0A336N1M2   A0A146LGX8   A0A336N8Y0   A0A1L8E1N4   A0A1L8E1A0   A0A069DT57   A0A1B6JC83   A0A1B6J9R3   A0A1B6JUU9   A0A1B6GNV9   E2C426   A0A224XHY9   A0A1W4WVN6   K7IWX6   A0A0M3QVF1   B4MIV5   A0A023F7R0   A0A1A9WV10   A0A1A9ZQM3   B4JVN4   A0A1I8Q911   A0A2P8Y7V2   A0A1B6DAR5   E0VBV0   J9JT12   W8BE37   A0A2S2PYY3   A0A034V763   A0A034V3U1   A0A2P2HXA1   A0A0K8WBT9   B4KML5   B4MCL3   A0A2R7X2G4   T1HNQ1   A0A0P4W4B8   R4G564   A0A2S2NUM9   A0A131Y4G8   B7PCK7   A0A0P4W714   A0A0H5R619   V5HJR5   A0A3M6UWS7   B3RIQ9   A0A1I8MJC0   A0A0A1XT11   A7STD8   R7U587   A0A369SL93   W4YY66   R7UFS0   A0A1Y1HII1   V4A763   F4QEX9   A0A3S1I0V8   A0A3B4TM41   G3NB04   A0A2I4CZY0   A0A3B4WDI1   A0A1A9X9R9   A0A1B0C0J8   Q54IA4   A0A060WQB7   A0A2U9CY02   E6ZI90   C1C161   A0A3Q3MV71   A0A0G4J309   A0A3P9NUS1   A0A3Q1EZM5   A0A0N8JVH2   A0A146NT24   I3KNE3   A0A3P8SG34   A0A3B3CH26   A0A0P5R3E3   A0A0N8EED7   H2LKX9   A0A3Q2WKU1   A0A0P5WQV3   A0A3Q0RS24   A0A0P5XIR5   A0A3P9DH51   H3CTL4   A0A3Q2PS46  

EC Number

2.4.1.-

Pubmed

19121390    26354079    26227816    22118469    24508170    30249741    + More
21347285    21719571    24845553    26823975    26334808    20798317    20075255    17994087    25474469    29403074    20566863    24495485    25348373    27129103    25765539    30382153    18719581    25315136    25830018    17615350    23254933    30042472    24865297    21757610    15875012    24755649    25186727    29451363    17554307    15496914   

EMBL

BABH01024106    GDQN01008572    JAT82482.1    KQ458859    KPJ04848.1    JTDY01000885    + More
KOB75558.1    AGBW02009528    OWR50588.1    KK107459    QOIP01000004    EZA50380.1    RLU23715.1    ADTU01011316    NEVH01006600    PNF37418.1    GL888932    EGI57180.1    KK852954    KDR13289.1    GECU01010876    JAS96830.1    GECU01030814    JAS76892.1    KQ977059    KYN06013.1    UFQS01005052    UFQT01005052    SSX16682.1    SSX35875.1    GDHC01012417    JAQ06212.1    UFQS01003696    UFQT01003696    SSX15864.1    SSX35208.1    GFDF01001602    JAV12482.1    GFDF01001603    JAV12481.1    GBGD01001754    JAC87135.1    GECU01010907    GECU01002551    JAS96799.1    JAT05156.1    GECU01011837    JAS95869.1    GECU01036594    GECU01028258    GECU01004726    JAS71112.1    JAS79448.1    JAT02981.1    GECZ01005655    JAS64114.1    GL452364    EFN77412.1    GFTR01005762    JAW10664.1    AAZX01009385    CP012524    ALC42309.1    CH963719    EDW72044.2    GBBI01001444    JAC17268.1    CH916375    EDV98502.1    PYGN01000823    PSN40336.1    GEDC01014566    JAS22732.1    DS235042    EEB10856.1    ABLF02009097    GAMC01011287    JAB95268.1    GGMS01001533    MBY70736.1    GAKP01020993    GAKP01020990    JAC37962.1    GAKP01020992    GAKP01020991    JAC37961.1    IACF01000655    LAB66417.1    GDHF01003688    GDHF01000021    JAI48626.1    JAI52293.1    CH933808    EDW10862.1    CH940659    EDW71401.1    KK856473    PTY25851.1    ACPB03007520    GDKW01000408    JAI56187.1    GAHY01000181    JAA77329.1    GGMR01007817    MBY20436.1    GEFM01002850    JAP72946.1    ABJB010474095    DS684369    EEC04329.1    GDRN01086856    JAI61114.1    HACM01008839    CRZ09281.1    GANP01010725    JAB73743.1    RCHS01000548    RMX58070.1    DS985241    EDV29023.1    GBXI01000106    JAD14186.1    DS469794    EDO33030.1    AMQN01026870    KB307513    ELT98841.1    NOWV01000004    RDD47244.1    AAGJ04003702    AAGJ04003703    AMQN01001554    KB303857    ELU02643.1    DF236959    GAQ78300.1    KB202325    ESO90830.1    GL883029    EGG14186.1    RQTK01000042    RUS90035.1    JXJN01023653    AAFI02000126    FR904577    CDQ67229.1    CP026263    AWP20910.1    FQ310508    CBN81774.1    BT080590    ACO15014.1    CDSF01000122    OVEO01000010    CEP01960.1    SPQ98819.1    JARO02014602    KPP58129.1    GCES01151444    JAQ34878.1    AERX01067164    GDIQ01126041    JAL25685.1    GDIQ01034972    LRGB01000190    JAN59765.1    KZS20491.1    GDIP01082906    JAM20809.1    GDIP01071563    JAM32152.1   

Proteomes

UP000005204    UP000053268    UP000037510    UP000007151    UP000053097    UP000279307    + More
UP000005205    UP000235965    UP000007755    UP000027135    UP000078542    UP000008237    UP000192223    UP000002358    UP000092553    UP000007798    UP000091820    UP000092445    UP000001070    UP000095300    UP000245037    UP000009046    UP000007819    UP000009192    UP000008792    UP000015103    UP000001555    UP000275408    UP000009022    UP000095301    UP000001593    UP000014760    UP000253843    UP000007110    UP000054558    UP000030746    UP000007797    UP000271974    UP000261420    UP000007635    UP000192220    UP000261360    UP000092443    UP000092460    UP000002195    UP000193380    UP000246464    UP000261640    UP000039324    UP000290189    UP000242638    UP000257200    UP000034805    UP000192224    UP000005207    UP000265080    UP000261560    UP000076858    UP000001038    UP000264840    UP000261340    UP000265160    UP000007303    UP000265000   

PRIDE

H9IS94    Q54IA4   

Pfam

PF05007   Mannosyl_trans

Interpro

IPR007704   PIG-M       

ProteinModelPortal

H9IS94   A0A1E1W669   A0A194QH28   A0A0L7LJ24   A0A212FA37   A0A026W2R9   + More
A0A158NC27   A0A2J7R9A6   F4X8B0   A0A067QTY4   A0A1B6JC24   A0A1B6HQE1   A0A151IMB5   A0A336N1M2   A0A146LGX8   A0A336N8Y0   A0A1L8E1N4   A0A1L8E1A0   A0A069DT57   A0A1B6JC83   A0A1B6J9R3   A0A1B6JUU9   A0A1B6GNV9   E2C426   A0A224XHY9   A0A1W4WVN6   K7IWX6   A0A0M3QVF1   B4MIV5   A0A023F7R0   A0A1A9WV10   A0A1A9ZQM3   B4JVN4   A0A1I8Q911   A0A2P8Y7V2   A0A1B6DAR5   E0VBV0   J9JT12   W8BE37   A0A2S2PYY3   A0A034V763   A0A034V3U1   A0A2P2HXA1   A0A0K8WBT9   B4KML5   B4MCL3   A0A2R7X2G4   T1HNQ1   A0A0P4W4B8   R4G564   A0A2S2NUM9   A0A131Y4G8   B7PCK7   A0A0P4W714   A0A0H5R619   V5HJR5   A0A3M6UWS7   B3RIQ9   A0A1I8MJC0   A0A0A1XT11   A7STD8   R7U587   A0A369SL93   W4YY66   R7UFS0   A0A1Y1HII1   V4A763   F4QEX9   A0A3S1I0V8   A0A3B4TM41   G3NB04   A0A2I4CZY0   A0A3B4WDI1   A0A1A9X9R9   A0A1B0C0J8   Q54IA4   A0A060WQB7   A0A2U9CY02   E6ZI90   C1C161   A0A3Q3MV71   A0A0G4J309   A0A3P9NUS1   A0A3Q1EZM5   A0A0N8JVH2   A0A146NT24   I3KNE3   A0A3P8SG34   A0A3B3CH26   A0A0P5R3E3   A0A0N8EED7   H2LKX9   A0A3Q2WKU1   A0A0P5WQV3   A0A3Q0RS24   A0A0P5XIR5   A0A3P9DH51   H3CTL4   A0A3Q2PS46  

KEGG

101737047    K05284 GPI mannosyltransferase 1 subunit M [EC:2.4.1.-] | (RefSeq) GPI mannosyltransferase 1

PATHWAY

00563    Glycosylphosphatidylinositol (GPI)-anchor biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0006506   GO:0016758   GO:0005789   GO:0016021   GO:0016757   GO:0005739   GO:0001784   GO:0006816   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

PANTHER

PTHR12886  

Subcellular location

Endoplasmic reticulum membrane  

Length:

428

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

174.7631

Exp number, first 60 AAs:

19.84649

Total prob of N-in:

0.53580

POSSIBLE N-term signal

sequence

outside

1  -  9

TMhelix

10  -  32

inside

33  -  170

TMhelix

171  -  193

outside

194  -  223

TMhelix

224  -  246

inside

247  -  323

TMhelix

324  -  346

outside

347  -  355

TMhelix

356  -  373

inside

374  -  384

TMhelix

385  -  407

outside

408  -  428

 

 

Pi

272.089521

Theta

192.602978

Tajima's D

1.218436

CLR

0.000011

CSRT

0.715714214289285

Interpretation

Uncertain