Gene

KWMTBOMO14412  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000120

Annotation

PREDICTED:_vacuolar_protein_sorting-associated_protein_26B-like_[Amyelois_transitella]

Location

Bomo_Chr24(+):5623774-5625445      View in EpiBrowser

Full name

Vacuolar protein sorting-associated protein 26      

Alternative Name

VPS26 protein homolog

Location in the cell

Cytoplasmic   Reliability : 2.174 Nuclear   Reliability : 2.409

CDS

ATGAGCTTTTTCGGGTTCGGTCAGACGGCGGATATCGAAATAGTTTTTGATGATGCTGACAAACGGAAGGTGGCTGAAGTGAAAACGGACGATGGTAAAAAAGAAAAGTTATTGTTGTATTATGACGGTGAAACGGTCTCCGGGAAAGTGAATGTGACGTTGCGGAAACCGGGATCAAAACTTGAACATCAAGGCATCAAGGTCGAACTCATAGGTCAGATTGAATTATTCTACGACAGAGGTAATCATCACGAATTCATATCTCTGGTTAAAGAACTAGCGCGTCCGGGCGACCTGCTTCAACACACGTCGTATCCTTTCGAGTTTGCTAATGTCGAAAAACCATACGAAGTATATACAGGCTCTAATGTCAGGTTGCGGTATTTCCTGCGGGCGACAATCGTCCGGCGCCTCACTGACATCACCAAGGAGGTGGATATTGCCGTGCACACGCTCTGTAGTTATCCGGACGTCCTTAATTCTATAAAAATGGAAGTAGGCATAGAAGACTGTCTGCACATAGAGTTTGAATATAACAAATCAAAATATCATTTGAAAGACGTTATTGTTGGTAAAATTTATTTCTTACTGGTACGTATAAAAATCAAGCACATGGAAATATCAATAATCAAGAGAGAAACCACTGGATCTGGTCCCAATACGTTTACAGAAAATGAAACTGTAGCAAAGTATGAGATAATGGATGGTGCGCCAGTCAGGGGTGAAAGTATTCCTATCAGAGTGTTTTTGGCTGGCTATGACCTGACTCCGACTATGAGGGACATTAACAACAAATTTTCTGTCAGATACTACCTTAATTTAGTTTTGATGGACACTGAAGATCGTCGCTATTTCAAACAACAAGAGGTGATATTATGGAGGAAGAGTGACAAGTCCAGATTACCCTTGCATCCTCATCACCCACAAACAGTGTCATATCAAGGCCATCAGTCATTAAGAAAACAAAGTGTTTCCAGTGATGATAATTCAGCTCGAGCAACACCATCAAATCCTGATCCTGAGAATGTAATGCAGAGATCAGTGTCCCCCTCAATGCCTGAAAAACAGAATGGACCCTTACAAATGGAGAGAGAAAAACCTGAAGCATTCATAGACAAATTAGCAGGTGCTCATATTAATGAAAATGATACTAACGATACGAGTGATGAGATTGAAGAACCGAAACCCGTCGAAAAACTTCCCGTAGTGGATAAACCTTTAATCGCCGAAAAACCTCAGATTGCTGAAAAACCTACCCTAAACCGACCTGAGCCTGCAGGGAGTCCGAATCAATAG

Protein

MSFFGFGQTADIEIVFDDADKRKVAEVKTDDGKKEKLLLYYDGETVSGKVNVTLRKPGSKLEHQGIKVELIGQIELFYDRGNHHEFISLVKELARPGDLLQHTSYPFEFANVEKPYEVYTGSNVRLRYFLRATIVRRLTDITKEVDIAVHTLCSYPDVLNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEISIIKRETTGSGPNTFTENETVAKYEIMDGAPVRGESIPIRVFLAGYDLTPTMRDINNKFSVRYYLNLVLMDTEDRRYFKQQEVILWRKSDKSRLPLHPHHPQTVSYQGHQSLRKQSVSSDDNSARATPSNPDPENVMQRSVSPSMPEKQNGPLQMEREKPEAFIDKLAGAHINENDTNDTSDEIEEPKPVEKLPVVDKPLIAEKPQIAEKPTLNRPEPAGSPNQ

Description

Component of the retromer complex which acts in conjunction with wingless (wg) and clathrin-mediated endocytosis to sustain a wntless (wls) traffic loop. This loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, thereby enabling wls to direct wg secretion. The hh and dpp signaling pathways do not require the retromer complex suggesting that it does not play a general role in exocytosis.

Subunit

Component of the retromer complex, composed of Vps26 and Vps35.

Similarity

Belongs to the VPS26 family.

Keywords

Complete proteome   Cytoplasm   Membrane   Protein transport   Reference proteome   Transport   Wnt signaling pathway  

Feature

chain  Vacuolar protein sorting-associated protein 26

Uniprot

H9IS93   A0A2H1WUD2   A0A2A4JV15   A0A0L7LJC9   A0A3S2TG18   A0A194QMZ1   + More
A0A194RJK5   A0A212FA24   A0A1L8DVC7   A0A336M094   A0A336MUK6   A0A0K8TSB1   U5EWK8   D2A583   A0A0T6BD35   A0A1I8MNP2   A0A2M4AFJ4   A0A1Q3F910   A0A1Q3F8S6   A0A2M3Z479   A0A2M4AFT7   A0A2M4BHM7   A0A2M4BHJ9   A0A2M4BHS7   W5J8V2   D3TNJ9   A0A0L0C435   A0A2M3Z426   A0A1S4G1K5   A0A182XP88   A0A067QYJ0   Q7Q5Y3   A0A2J7Q1J4   A0A0A1WRR9   A0A1A9WA17   A0A182Y2R6   A0A182KNZ4   A0A1A9XM10   A0A034WM28   A0A182I1D8   A0A1Y9HDZ0   A0A182UPZ1   A0A182FEI9   A0A182GF45   A0A1A9Z3Y4   A0A2M3Z558   W8BR63   A0A1W4X737   A0A226CXH6   A0A182JPN5   A0A182LXX7   A0A1A9VWW5   A0A1E1XTV5   A0A182IL17   A0A1J1J444   A0A084WEQ8   A0A182PDS1   A0A023GLK5   G3MM37   A0A1E1X9Z7   A0A0K8W0J3   A0A0M4FAP9   A0A023FIT6   Q16KJ7   A0A1B6L663   A0A1B6FGW5   B7PQ07   V5H0U0   V9ILB7   A0A088A5E3   A0A1B6H6C5   A0A1S3HY72   A0A2A3E6Q0   A0A0M9A5I2   A0A0C9RVK4   A0A3L8DE08   A0A0V0GA44   T1HIG2   A0A069DYT0   A0A023FWI7   A0A2R5LJQ5   A0A224XEF2   B4PY70   V3ZKD4   A0A151I0X6   Q9W552   B4I9J7   A0A0L7R868  

Pubmed

19121390    26227816    26354079    22118469    26369729    18362917    + More
19820115    25315136    20920257    23761445    20353571    26108605    17510324    24845553    12364791    14747013    17210077    25830018    25244985    20966253    25348373    26483478    24495485    29209593    24438588    22216098    28503490    25765539    30249741    26334808    17994087    17550304    23254933    10731132    12537572    10731137    12537569    18193032   

EMBL

BABH01024106    ODYU01010731    SOQ56024.1    NWSH01000581    PCG75528.1    JTDY01000885    + More
KOB75557.1    RSAL01000179    RVE44970.1    KQ458859    KPJ04851.1    KQ460124    KPJ17619.1    AGBW02009528    OWR50587.1    GFDF01003704    JAV10380.1    UFQT01000242    SSX22263.1    UFQS01002031    UFQT01002031    SSX13023.1    SSX32463.1    GDAI01000359    JAI17244.1    GANO01002912    JAB56959.1    KQ971345    EFA05114.1    LJIG01001689    KRT85251.1    GGFK01006233    MBW39554.1    GFDL01010995    JAV24050.1    GFDL01011074    JAV23971.1    GGFM01002552    MBW23303.1    GGFK01006261    MBW39582.1    GGFJ01003401    MBW52542.1    GGFJ01003371    MBW52512.1    GGFJ01003370    MBW52511.1    ADMH02002097    ETN59229.1    CCAG010023252    EZ423001    ADD19277.1    JRES01000940    KNC27001.1    GGFM01002515    MBW23266.1    KK852822    KDR15525.1    AAAB01008960    EAA10832.4    EDO63799.1    NEVH01019406    PNF22447.1    GBXI01013077    JAD01215.1    GAKP01002326    JAC56626.1    APCN01000054    JXUM01059195    KQ562039    KXJ76842.1    GGFM01002908    MBW23659.1    GAMC01002765    JAC03791.1    LNIX01000061    OXA37238.1    AXCM01003909    GFAA01000706    JAU02729.1    CVRI01000070    CRL07175.1    ATLV01023245    KE525341    KFB48702.1    GBBM01001718    JAC33700.1    JO842938    AEO34555.1    GFAC01003146    JAT96042.1    GDHF01007710    JAI44604.1    CP012528    ALC49520.1    GBBK01002975    JAC21507.1    CH477953    EAT34835.1    GEBQ01020971    GEBQ01020769    JAT19006.1    JAT19208.1    GECZ01030060    GECZ01020342    GECZ01008133    JAS39709.1    JAS49427.1    JAS61636.1    ABJB010160378    ABJB010289233    ABJB010500975    DS762323    EEC08679.1    GANP01007873    GEFM01003773    JAB76595.1    JAP72023.1    JR053141    AEY61860.1    GECU01037460    GECU01033474    GECU01032347    GECU01018781    GECU01016243    GECU01013012    GECU01000961    JAS70246.1    JAS74232.1    JAS75359.1    JAS88925.1    JAS91463.1    JAS94694.1    JAT06746.1    KZ288364    PBC26896.1    KQ435729    KOX77647.1    GBYB01012975    JAG82742.1    QOIP01000009    RLU18634.1    GECL01001858    JAP04266.1    ACPB03010282    GBGD01001855    JAC87034.1    GBBL01001456    JAC25864.1    GGLE01005610    MBY09736.1    GFTR01005570    JAW10856.1    CM000162    EDX00943.1    KB202199    ESO91783.1    KQ976600    KYM79464.1    AE014298    AL021106    BT023502    AY060842    CH480825    EDW43878.1    KQ414633    KOC67075.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000283053    UP000053268    UP000053240    + More
UP000007151    UP000007266    UP000095301    UP000000673    UP000092444    UP000037069    UP000076407    UP000027135    UP000007062    UP000235965    UP000091820    UP000076408    UP000075882    UP000092443    UP000075840    UP000075900    UP000075903    UP000069272    UP000069940    UP000249989    UP000092445    UP000192223    UP000198287    UP000075881    UP000075883    UP000078200    UP000075880    UP000183832    UP000030765    UP000075885    UP000092553    UP000008820    UP000001555    UP000005203    UP000085678    UP000242457    UP000053105    UP000279307    UP000015103    UP000002282    UP000030746    UP000078540    UP000000803    UP000001292    UP000053825   

PRIDE

H9IS93    Q9W552   

Pfam

PF03643   Vps26        + More
PF13855   LRR_8

Interpro

IPR014752   Arrestin_C        + More
IPR028934   Vps26-related       
IPR032675   LRR_dom_sf       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR001611   Leu-rich_rpt       
IPR014756   Ig_E-set       

SUPFAM

SSF81296   SSF81296       

Gene 3D

2.60.40.640     3.80.10.10    

ProteinModelPortal

H9IS93   A0A2H1WUD2   A0A2A4JV15   A0A0L7LJC9   A0A3S2TG18   A0A194QMZ1   + More
A0A194RJK5   A0A212FA24   A0A1L8DVC7   A0A336M094   A0A336MUK6   A0A0K8TSB1   U5EWK8   D2A583   A0A0T6BD35   A0A1I8MNP2   A0A2M4AFJ4   A0A1Q3F910   A0A1Q3F8S6   A0A2M3Z479   A0A2M4AFT7   A0A2M4BHM7   A0A2M4BHJ9   A0A2M4BHS7   W5J8V2   D3TNJ9   A0A0L0C435   A0A2M3Z426   A0A1S4G1K5   A0A182XP88   A0A067QYJ0   Q7Q5Y3   A0A2J7Q1J4   A0A0A1WRR9   A0A1A9WA17   A0A182Y2R6   A0A182KNZ4   A0A1A9XM10   A0A034WM28   A0A182I1D8   A0A1Y9HDZ0   A0A182UPZ1   A0A182FEI9   A0A182GF45   A0A1A9Z3Y4   A0A2M3Z558   W8BR63   A0A1W4X737   A0A226CXH6   A0A182JPN5   A0A182LXX7   A0A1A9VWW5   A0A1E1XTV5   A0A182IL17   A0A1J1J444   A0A084WEQ8   A0A182PDS1   A0A023GLK5   G3MM37   A0A1E1X9Z7   A0A0K8W0J3   A0A0M4FAP9   A0A023FIT6   Q16KJ7   A0A1B6L663   A0A1B6FGW5   B7PQ07   V5H0U0   V9ILB7   A0A088A5E3   A0A1B6H6C5   A0A1S3HY72   A0A2A3E6Q0   A0A0M9A5I2   A0A0C9RVK4   A0A3L8DE08   A0A0V0GA44   T1HIG2   A0A069DYT0   A0A023FWI7   A0A2R5LJQ5   A0A224XEF2   B4PY70   V3ZKD4   A0A151I0X6   Q9W552   B4I9J7   A0A0L7R868  

PDB

2R51     E-value=2.04418e-131,     Score=1202

KEGG

101736916    K18466 vacuolar protein sorting-associated protein 26 | (RefSeq) vacuolar protein sorting-associated

PATHWAY

04144    Endocytosis - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0005768   GO:0042147   GO:0005829   GO:0006886   GO:0030904   GO:0030111   GO:0016055   GO:0030906  

PANTHER

PTHR12233  

Subcellular location

Cytoplasm  
Membrane  

Length:

431

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0011

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00092

outside

1  -  431

 

 

Pi

203.410464

Theta

177.033701

Tajima's D

0.546991

CLR

0.039664

CSRT

0.529173541322934

Interpretation

Uncertain