Gene

KWMTBOMO14399  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000114

Annotation

PREDICTED:_protein_FAM98A_[Amyelois_transitella]

Location

Bomo_Chr24(-):5324473-5329508      View in EpiBrowser

Full name

Protein FAM98A      

Location in the cell

Nuclear   Reliability : 3.002

CDS

ATGGAAAACGAAATATTGGACTCACTTAGCGACTTGAGCTATGAAGGCCCACTCTCCGAAGAAGCTGTCTTTGCAAAGGCTATTGAGGGAGGTGCCAAGTCCCTTGACTTCACCAAACTTGTGCATATATTGGCTGAAGAGTTGAAGAATCTCTGTCACCTCGAAGAGACTGTAAACATGATTAATGATCCAGACGATTCAAGCTCTTTCCTGCTGGAACTTAGTTCATTTTTGAAAGAATTGGGATGTCCCTACAAGAAATTGGTAACAGGTCATATGTCATCTCGACTACAATCTAAAGACGATCGTCTGTTACTGCTTGATTACCTGATCTCCGAGCTCATGGCAGCTAGAATGGTGAATGTAGATCGTCCACAAGATAAGGGCTCAGGCATGGAGATTGTTATGCGTGAATCTCCAACAGCCAAAGATCTCAAAGATATATTGATTACTCTAAAATTCAACAAACCACCACCGAATATCACTCCAGAAGTGCTATTCTCCAAGCTGGAAGGAAAGTTAAAGGATACCATACAAAAGGAAGGTGAACAATTAGTTGGTAAGCCACTCTACAACAAGGCTTTAAGTGACAAAGATTGGAAACAATTGGAGACAAGCTTCACGGAGATGTTTGAAGAATACAGACTAAGGAGAGAGACACTTATAACCAGATTGGAATGTACCATACAAAGTTTTGAGTGGTCAGATCGATTGAAAACGCAGAAGGACGCAATCCAGTCCACTTATCGTCCGAAACGGGAACATCTGAAACCGAAGCCAGATGTGAAACTGTCAGACTTCTTAGCGGCCAGAACGTCGCTGCTGCAAGTAGAGAAGACTTCCAGTGCTACTGTTAGAAAGAATACCAGAAGCGATGTCAACAAAGTTCTCATCGGACAAGTACCAGACCGAGGTGGTAGACCCAATGAGCAGCAACCTCCACCGCCAGAGATGCCCTCCTGGCAACAGAGATCATCAGCTCCGGAATAA

Protein

MENEILDSLSDLSYEGPLSEEAVFAKAIEGGAKSLDFTKLVHILAEELKNLCHLEETVNMINDPDDSSSFLLELSSFLKELGCPYKKLVTGHMSSRLQSKDDRLLLLDYLISELMAARMVNVDRPQDKGSGMEIVMRESPTAKDLKDILITLKFNKPPPNITPEVLFSKLEGKLKDTIQKEGEQLVGKPLYNKALSDKDWKQLETSFTEMFEEYRLRRETLITRLECTIQSFEWSDRLKTQKDAIQSTYRPKREHLKPKPDVKLSDFLAARTSLLQVEKTSSATVRKNTRSDVNKVLIGQVPDRGGRPNEQQPPPPEMPSWQQRSSAPE

Description

Positively stimulates PRMT1-induced protein arginine methylation (PubMed:28040436). Involved in skeletal homeostasis (By similarity). Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity). Promotes colorectal cancer cell malignancy (PubMed:28040436).

Subunit

Interacts (via N- and C-terminus) with DDX1 (PubMed:28040436). Interacts (via N- and C-terminus) with C14orf166 (PubMed:28040436). Interacts with FAM98B (PubMed:28040436). Interacts with PLEKHM1 (via N- and C-terminus) (By similarity).

Similarity

Belongs to the FAM98 family.

Keywords

Alternative splicing   Complete proteome   Reference proteome  

Feature

chain  Protein FAM98A
splice variant  In isoform 2.

Uniprot

A0A2H1W232   A0A3S2LV25   A0A212FB64   A0A194Q6J2   A0A0N1IFJ5   A0A067QTE2   + More
A0A2J7PH46   A0A2R5LBI9   A0A1Z5L4M4   D6W6E5   T1JGC5   V5I477   A0A023GJB9   A0A131ZB30   G3MHZ1   B7P5Z4   A0A224YFT9   A0A131XAH4   L7MKY4   A0A1E1XAK8   A0A2P8XFR2   A0A2P2HZK1   A0A3L8DS30   A0A1B6EY61   E9I9Z5   A0A1B6KUJ4   A0A026VZS9   A0A293MHA7   A0A1S3HQE4   A0A0J7KZ19   A0A1S3HEQ0   E2BGQ8   A0A0V0GCH0   A0A0C9QYI8   E1ZVE7   A0A0P4VIA0   A0A151IDL6   A0A0T6B6D7   U4TUM2   N6UI84   A0A0C9Q474   U4TR51   A0A158NBN1   A0A023EZR9   A0A1B6DHD0   K7IMX3   A0A195DR60   A0A195BF96   A0A232ERX4   A0A088ALH1   T1IGF7   A0A2A3E9C3   A0A2R7WIP4   A0A1B6DQK3   A0A195FDM7   A0A1Y1K740   F4X8H8   A0A146MBJ7   A0A2Y9D8T6   A0A0D9RHG5   A0A224XR24   A0A1U7Q9A9   A0A023FYX6   A0A3Q2LHB5   A0A2K6FX23   A0A1S2ZZB8   A0A2I0UST4   A0A0B8RSM1   A0A0A9XIT1   A0A2R9BLM0   G2HFC6   A0A2K5PIB1   H2P6I4   G3TUI6   L5KT45   F6Z4V6   A0A2K5F254   A0A2K6UZL7   U3EAA8   G1S1Q0   A0A2K6CAT6   A0A2K6N3J4   A0A2K5UTV3   A0A2K5YP75   A0A096NY88   A0A2K6QH79   A0A2K5M8R7   A0A2K5HFJ5   F7BNZ9   G3SJ47   A0A2J8VNN2   U3KC21   A0A2K6UZI2   A0A2K6CAS4   Q8NCA5-2   U6DPP6  

Pubmed

22118469    26354079    24845553    28528879    18362917    19820115    + More
25765539    26830274    22216098    28797301    28049606    25576852    28503490    29403074    30249741    21282665    24508170    20798317    27129103    23537049    21347285    25474469    20075255    28648823    28004739    21719571    26823975    19892987    25401762    22722832    16136131    21484476    23258410    25243066    25362486    17431167    25319552    22398555    14702039    15815621    15489334    17974005    21269460    24275569    28040436   

EMBL

ODYU01005854    SOQ47150.1    RSAL01000179    RVE44956.1    AGBW02009370    OWR50984.1    + More
KQ459386    KPJ01157.1    KQ460254    KPJ16343.1    KK852954    KDR13278.1    NEVH01025150    PNF15657.1    GGLE01002768    MBY06894.1    GFJQ02004671    JAW02299.1    KQ971319    EFA11389.1    JH432201    GANP01001500    JAB82968.1    GBBM01001414    JAC34004.1    GEDV01000399    JAP88158.1    JO841492    AEO33109.1    ABJB010137399    ABJB010255654    DS643033    EEC02016.1    GFPF01004689    MAA15835.1    GEFH01005054    JAP63527.1    GACK01000419    JAA64615.1    GFAC01002894    JAT96294.1    PYGN01002299    PSN30858.1    IACF01001358    LAB67066.1    QOIP01000004    RLU23214.1    GECZ01026841    JAS42928.1    GL761864    EFZ22605.1    GEBQ01024858    JAT15119.1    KK107638    EZA48389.1    GFWV01020359    MAA45087.1    LBMM01001902    KMQ95576.1    GL448204    EFN85128.1    GECL01001058    JAP05066.1    GBYB01008844    JAG78611.1    GL434492    EFN74857.1    GDKW01003047    JAI53548.1    KQ977936    KYM98540.1    LJIG01009611    KRT82734.1    KB630496    ERL83633.1    APGK01034531    KB740914    ENN78362.1    GBYB01008843    JAG78610.1    KB630891    ERL83929.1    ADTU01011228    GBBI01003972    JAC14740.1    GEDC01012202    JAS25096.1    KQ980581    KYN15331.1    KQ976500    KYM83243.1    NNAY01002540    OXU21109.1    ACPB03009001    KZ288324    PBC28074.1    KK854879    PTY19428.1    GEDC01009334    JAS27964.1    KQ981673    KYN38307.1    GEZM01095981    JAV55226.1    GL888932    EGI57247.1    GDHC01002442    JAQ16187.1    AQIB01035434    AQIB01035435    AQIB01035436    GFTR01005997    JAW10429.1    GBBL01001420    JAC25900.1    KZ505642    PKU49114.1    GBRD01010144    JAG55680.1    GBHO01023700    JAG19904.1    AJFE02075972    AACZ04002019    AK305440    GABC01005360    GABF01001818    GABD01002048    GABE01001045    NBAG03000318    BAK62434.1    JAA05978.1    JAA20327.1    JAA31052.1    JAA43694.1    PNI41319.1    ABGA01114060    ABGA01114061    ABGA01114062    ABGA01114063    KB030580    ELK14121.1    GAMT01004483    GAMS01004236    GAMR01009897    GAMQ01002366    GAMP01008402    JAB07378.1    JAB18900.1    JAB24035.1    JAB39485.1    JAB44353.1    ADFV01011677    ADFV01011678    AQIA01018581    AHZZ02005170    JSUE03010547    JU475068    JV046689    AFH31872.1    AFI36760.1    CABD030013508    NDHI03003415    PNJ59128.1    AGTO01000393    AK074867    CH471053    BC136768    BC136770    AL049943    HAAF01012821    CCP84644.1   

Proteomes

UP000283053    UP000007151    UP000053268    UP000053240    UP000027135    UP000235965    + More
UP000007266    UP000001555    UP000245037    UP000279307    UP000053097    UP000085678    UP000036403    UP000008237    UP000000311    UP000078542    UP000030742    UP000019118    UP000005205    UP000002358    UP000078492    UP000078540    UP000215335    UP000005203    UP000015103    UP000242457    UP000078541    UP000007755    UP000248480    UP000029965    UP000189706    UP000002281    UP000233160    UP000079721    UP000240080    UP000002277    UP000233040    UP000001595    UP000007646    UP000010552    UP000233020    UP000233220    UP000008225    UP000001073    UP000233120    UP000233180    UP000233100    UP000233140    UP000028761    UP000233200    UP000233060    UP000233080    UP000006718    UP000001519    UP000016665    UP000005640   

PRIDE

L7MKY4    F6Z4V6    Q8NCA5   

Pfam

PF10239   DUF2465

Interpro

IPR018797   FAM98        + More
IPR006162   Ppantetheine_attach_site       

ProteinModelPortal

A0A2H1W232   A0A3S2LV25   A0A212FB64   A0A194Q6J2   A0A0N1IFJ5   A0A067QTE2   + More
A0A2J7PH46   A0A2R5LBI9   A0A1Z5L4M4   D6W6E5   T1JGC5   V5I477   A0A023GJB9   A0A131ZB30   G3MHZ1   B7P5Z4   A0A224YFT9   A0A131XAH4   L7MKY4   A0A1E1XAK8   A0A2P8XFR2   A0A2P2HZK1   A0A3L8DS30   A0A1B6EY61   E9I9Z5   A0A1B6KUJ4   A0A026VZS9   A0A293MHA7   A0A1S3HQE4   A0A0J7KZ19   A0A1S3HEQ0   E2BGQ8   A0A0V0GCH0   A0A0C9QYI8   E1ZVE7   A0A0P4VIA0   A0A151IDL6   A0A0T6B6D7   U4TUM2   N6UI84   A0A0C9Q474   U4TR51   A0A158NBN1   A0A023EZR9   A0A1B6DHD0   K7IMX3   A0A195DR60   A0A195BF96   A0A232ERX4   A0A088ALH1   T1IGF7   A0A2A3E9C3   A0A2R7WIP4   A0A1B6DQK3   A0A195FDM7   A0A1Y1K740   F4X8H8   A0A146MBJ7   A0A2Y9D8T6   A0A0D9RHG5   A0A224XR24   A0A1U7Q9A9   A0A023FYX6   A0A3Q2LHB5   A0A2K6FX23   A0A1S2ZZB8   A0A2I0UST4   A0A0B8RSM1   A0A0A9XIT1   A0A2R9BLM0   G2HFC6   A0A2K5PIB1   H2P6I4   G3TUI6   L5KT45   F6Z4V6   A0A2K5F254   A0A2K6UZL7   U3EAA8   G1S1Q0   A0A2K6CAT6   A0A2K6N3J4   A0A2K5UTV3   A0A2K5YP75   A0A096NY88   A0A2K6QH79   A0A2K5M8R7   A0A2K5HFJ5   F7BNZ9   G3SJ47   A0A2J8VNN2   U3KC21   A0A2K6UZI2   A0A2K6CAS4   Q8NCA5-2   U6DPP6  

KEGG

101743964    no KO assigned | (RefSeq) protein FAM98A

GO

GO:0072669   GO:0008284   GO:0008276   GO:0010628   GO:0032418   GO:1900029   GO:0006479   GO:0003723  

PANTHER

PTHR31353  

Length:

329

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00243

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00550

outside

1  -  329

 

 

Pi

191.123235

Theta

128.212288

Tajima's D

1.428726

CLR

0.154579

CSRT

0.770561471926404

Interpretation

Uncertain