Gene

KWMTBOMO14392

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr24(+):5122349-5125214      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 3.267

CDS

ATGGGGGACGCGGTCATTCTGGCAGGCGATCTAAATTGCCACCACACTAGGTGGAACTGCCATCGCACGAATGTGAACGGTAGGCGTCTCGACGCGTTCATAGACGACCTCACATTCGAGATATTCAACCCTCCGACCCCCACGTGCTATCCGTACAACGCCGCGCGTCGTCCGAGCACAATAGATCTGGCACTGCTGAGGAACGTAACTCTGCGCTTGCGCTCCATCGAGGCAATGTCAGAACTCGACTCAGACCACCGACCTGTCGTCATGCAGCTCGGTCGCCCACTCAACCGCGAACCAGATACGAGGACCATGGTGGATTGGAAGAAGCTGGGCACGTGCTTAGCTGACACCGCTCCACCAATCCTCCCTTGCGGCCCGGATTCAACTCCATCCCCCGAGGACACCGTCGAATCCATAAACATCTTCACTGATCACGTCTCGACGGCGATCACAAGATCTTCAAAGCAAGTCGATGTGGAGGACTGCTTCCACCGCATCAGACTTTCCCCCGATCTTAGGGACCTCGTAAGAGTTAGAAACGCGGCAATCCGGGCCTACGATCGATATCCCACGGATTCAAACCGGACTCGGATGCGTCGCTTACAGCGGGAGGTCAAATCCCGCTTGAGCGACGCCCGAAACGAAAACTGGGATAGTTATTTAAAAGAACTCGCGCCCACTCACCAAGCATACTGGCGACTAGCTAGGACCCTCAAGTCCGAAACTATCGTCACTATGCCGCCTCTCGTACGCCCCTCAGGCCAACCACCGGCTTACGATGACGATGACAAGGCAGAGTTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGCACCCCGAACACACCGAGCTAGTCGACAGGGAGGTCGAGCGCAGAGATTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTTCCAAGGTTAAGGAGGCGATCGATAGCCTACAACCACGGAAAGCTCCCGGCTCCGACGGCATCCGCAACCGCGCGCTTAAATTGTTACCAGCCCAACTGATAACGATGTTGGCCACCATATTAAATGCTGCTATGACGAACTGCATCTTTCCCGCGGCGTGGAAAGAAGCGGACGTTATCGGCATACACAAGCCGGGCAAACCGAAGAACGAAACCGCGAGTTACCGCCCCATCAGTCTCCTCCCGGCGATAGGCAAACTATACGAACGGCTCCTTCGTAAACGCCTCTGGGACTTCGTATCCGCGAATAAAATTCTCATAGACGAGCAGTTTGGATTCCGCGCCAGACACTCGTGCGTCCATCAAGTGCACCGCCTCACGGAGCACATCTTACTAGGGCTGAACAGGCGGAAACCCATTCCGACAGGAGCCCTCTTCTTCGATATAGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTGATATACAAACTGTATAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTACTTGTCGAACCGTTCGTTCCGATATCGAGTCGAGGGAACGCGTTCCCGGCCCCGTCACGTCACAGCCGGAGTCCCGCAAGGCTCCGCCCTCTCTCCGTTACTATTTAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTGGCGCTCTTCGCCGATGACACCGCCATCTACTACTCGTGTAGGAAGAAGGCGTTGCTTCATCGACGACTTCAGACCGCAGCTACCACCATGGGACAGTGGTTCCGGAAGTGGCGCATCGACATCAACCCCACGAAAAGCACAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAACACCACGCTGAGCATCCCCCTCCCGACTAGGCGCGTCAACACCTCCGCCCCCGCCGTTCGCCCAATCACGATGTTCGACCAGCCCATACCGTGGGCCCCGAAGGTCAAATATTTAGGCGTCACCCTCGACAGTAGGATGACATTCCGTCCTCACATCAAGACGGTACGCGACCGTGCCGCCTTCATTCTAGGACGTCTCTACCCGATGATATGTAGGCGAAGTAAAATGTCCCTTAGAAATAAGGTGACACTCTACAAAACTTGCATACGCCCCGTCATGACCTATGCAAGTGTAGTGTTCGCTCACGCGGCCCGCACTCACTTAAAGACATTCCAAATCATTCAATCCCGTTTTTGCAGGATAGCCGTCGGAGCCCCGTGGTTCGTCAGGAACGTCGACCTCCATGACGACCTGGACTTAGAGTCCACCAGTAAGTATATGCAGTCGGCGTCAATGCGCCACTTCGATAAAGCGGCACGACACGAGAACCCTCTCATCGTGGTCGCCGGTAACTACATTCCCGATCCTGCGGACAGAATGGAAAGCAGTCGGCGTCGCCCAAAACACGTCATCTCGGATCCTCCCGATCCACTAACGGTGCTTCTAGGTACTTCAAGCACCGGTCACCGTTCTCGTCGAACCCGTCGCTTGCGACGAAGGGCTCGACGAGTAAATTAA

Protein

MGDAVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEIFNPPTPTCYPYNAARRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPLNREPDTRTMVDWKKLGTCLADTAPPILPCGPDSTPSPEDTVESINIFTDHVSTAITRSSKQVDVEDCFHRIRLSPDLRDLVRVRNAAIRAYDRYPTDSNRTRMRRLQREVKSRLSDARNENWDSYLKELAPTHQAYWRLARTLKSETIVTMPPLVRPSGQPPAYDDDDKAELLADALQEQCTTSTQHAHPEHTELVDREVERRDSLPPSDALPPITTSKVKEAIDSLQPRKAPGSDGIRNRALKLLPAQLITMLATILNAAMTNCIFPAAWKEADVIGIHKPGKPKNETASYRPISLLPAIGKLYERLLRKRLWDFVSANKILIDEQFGFRARHSCVHQVHRLTEHILLGLNRRKPIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDYLSNRSFRYRVEGTRSRPRHVTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKKALLHRRLQTAATTMGQWFRKWRIDINPTKSTAVLFKRGRPPNTTLSIPLPTRRVNTSAPAVRPITMFDQPIPWAPKVKYLGVTLDSRMTFRPHIKTVRDRAAFILGRLYPMICRRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHLKTFQIIQSRFCRIAVGAPWFVRNVDLHDDLDLESTSKYMQSASMRHFDKAARHENPLIVVAGNYIPDPADRMESSRRRPKHVISDPPDPLTVLLGTSSTGHRSRRTRRLRRRARRVN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139WA11   A0A139W8G9   V5GNJ2   V5GNF3   A0A023EZE6   A0A023EYS8   A0A2S2QEE0   X1WLB2   A0A224XF24   Q07995   A0A2S2PPK8   A0A3N5Z7I3   A0A2S2Q383   J9KKL3   A0A2S2PR14   A0A2S2NGV8   A0A2J7R7D0   A0A2M4CV52   A0A224XB44   A0A2M4CV42   A0A2M4BEF4   A0A2M4BEZ9   A0A1Y1LKN6   J9LC21   A0A2M4BDA5   J9M522   A0A2M4BD62   A0A2M4BD66   A0A2J7PDM0   A0A2M4BD67   X1WZH0   A0A224X6Q4   A0A2M4BDV6   A0A224X6S1   D7GYA5   X1WNI2   A0A0L0CBP5   A0A087UGF5   A0A0A9YJ00   A0A1Y1KFR3   A0A2J7PVX3   A0A0A9YU04   Q8T9X4   A0A1B6EGD8   A0A2M4BD83   Q8I7P8   A0A2S2N814   A0A2S2P698   A0A224X6T4   J9JS95   K7IN67   A0A2S2PX53   A0A2S2NPG3   A0A2H8TF37   A0A2S2R9D4   A0A2J7QB68   A0A2J7R8R8   A0A2J7PQB5   J9LFC9   A0A0J7MYU2   A0A069DX78   A0A2J7QR37   D7EM17   A0A2J7QY69   A0A2A4K918   A0A2J7PBY3   A0A023F069   A0A224X6U5   A0A2S2Q352   A0A2H8U0H5   A0A0A9YSX4   A0A2A4IUM2   A0A224X6R6   A0A069DZL8   J9KC83   A0A2J7RD70   J9KLB1   A0A352X8G4   A0A224XJI0   A0A2J7Q0S7   J9KSK5   A0A2J7PU96   A0A224XI99   Q95SX7   A0A1W7R682   A0A2S2PHL7  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    8387152    30086797    26108605    25401762    20075255    26334808    30148503    7753626    12537569   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ971729    KYB24751.1    KQ973342    KXZ75569.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004571    JAC14141.1    GBBI01004395    JAC14317.1    GGMS01006359    MBY75562.1    ABLF02042518    ABLF02057746    GFTR01008038    JAW08388.1    S59870    AAB26437.2    GGMR01018716    MBY31335.1    RPOV01000134    RPJ78669.1    GGMS01002992    MBY72195.1    ABLF02029306    ABLF02029314    ABLF02060138    GGMR01019198    MBY31817.1    GGMR01003407    MBY16026.1    NEVH01006736    PNF36716.1    GGFL01004957    MBW69135.1    GFTR01008262    JAW08164.1    GGFL01005012    MBW69190.1    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1    GEZM01053022    JAV74219.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GGFJ01001842    MBW50983.1    ABLF02024246    GGFJ01001843    MBW50984.1    GGFJ01001844    MBW50985.1    NEVH01026386    PNF14434.1    GGFJ01001858    MBW50999.1    ABLF02034467    GFTR01008279    JAW08147.1    GGFJ01001857    MBW50998.1    GFTR01008271    JAW08155.1    KQ973363    EFA13335.2    ABLF02008153    ABLF02008462    ABLF02008464    JRES01000644    KNC29657.1    KK119692    KFM76444.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GEZM01084969    JAV60363.1    NEVH01020940    PNF20481.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    AF456125    AAL57609.1    GEDC01000337    JAS36961.1    GGFJ01001822    MBW50963.1    AY180919    AAN87272.1    GGMR01000676    MBY13295.1    GGMR01012305    MBY24924.1    GFTR01008261    JAW08165.1    ABLF02028535    ABLF02028545    GGMS01000737    MBY69940.1    GGMR01006408    MBY19027.1    GFXV01000908    MBW12713.1    GGMS01017365    MBY86568.1    NEVH01016302    PNF25823.1    NEVH01006721    PNF37225.1    NEVH01022639    PNF18527.1    ABLF02023911    LBMM01013518    KMQ85605.1    GBGD01000389    JAC88500.1    NEVH01011985    PNF31054.1    KQ973412    EFA12510.2    NEVH01009134    PNF33528.1    NWSH01000032    PCG80496.1    NEVH01027074    PNF13841.1    GBBI01003810    JAC14902.1    GFTR01008251    JAW08175.1    GGMS01002955    MBY72158.1    GFXV01007093    MBW18898.1    GBHO01008295    JAG35309.1    NWSH01007753    PCG62823.1    GFTR01008269    JAW08157.1    GBGD01000415    JAC88474.1    ABLF02033757    NEVH01005295    PNF38784.1    ABLF02040174    ABLF02040183    ABLF02055266    DNOY01000259    HBE18313.1    GFTR01008257    JAW08169.1    NEVH01019963    PNF22185.1    ABLF02014118    ABLF02014121    ABLF02054790    NEVH01021205    PNF19912.1    GFTR01008256    JAW08170.1    AY060438    AAL25477.1    GEHC01000968    JAV46677.1    GGMR01016296    MBY28915.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000037069    UP000054359    + More
UP000002358    UP000036403    UP000218220   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    Q8T9X4    Q8I7P8    Q95SX7    + More

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139WA11   A0A139W8G9   V5GNJ2   V5GNF3   A0A023EZE6   A0A023EYS8   A0A2S2QEE0   X1WLB2   A0A224XF24   Q07995   A0A2S2PPK8   A0A3N5Z7I3   A0A2S2Q383   J9KKL3   A0A2S2PR14   A0A2S2NGV8   A0A2J7R7D0   A0A2M4CV52   A0A224XB44   A0A2M4CV42   A0A2M4BEF4   A0A2M4BEZ9   A0A1Y1LKN6   J9LC21   A0A2M4BDA5   J9M522   A0A2M4BD62   A0A2M4BD66   A0A2J7PDM0   A0A2M4BD67   X1WZH0   A0A224X6Q4   A0A2M4BDV6   A0A224X6S1   D7GYA5   X1WNI2   A0A0L0CBP5   A0A087UGF5   A0A0A9YJ00   A0A1Y1KFR3   A0A2J7PVX3   A0A0A9YU04   Q8T9X4   A0A1B6EGD8   A0A2M4BD83   Q8I7P8   A0A2S2N814   A0A2S2P698   A0A224X6T4   J9JS95   K7IN67   A0A2S2PX53   A0A2S2NPG3   A0A2H8TF37   A0A2S2R9D4   A0A2J7QB68   A0A2J7R8R8   A0A2J7PQB5   J9LFC9   A0A0J7MYU2   A0A069DX78   A0A2J7QR37   D7EM17   A0A2J7QY69   A0A2A4K918   A0A2J7PBY3   A0A023F069   A0A224X6U5   A0A2S2Q352   A0A2H8U0H5   A0A0A9YSX4   A0A2A4IUM2   A0A224X6R6   A0A069DZL8   J9KC83   A0A2J7RD70   J9KLB1   A0A352X8G4   A0A224XJI0   A0A2J7Q0S7   J9KSK5   A0A2J7PU96   A0A224XI99   Q95SX7   A0A1W7R682   A0A2S2PHL7  

PDB

6AR3     E-value=0.00151239,     Score=102

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313   GO:0008270   GO:0003676  

Length:

828

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.572820000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00148

outside

1  -  828

 

 

Pi

2.402423

Theta

2.892618

Tajima's D

-0.93922

CLR

0.094982

CSRT

0.148442577871106

Interpretation

Uncertain