SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO14388
Pre Gene Modal
BGIBMGA013313
Annotation
PREDICTED:_LOW_QUALITY_PROTEIN:_E3_ubiquitin-protein_ligase_CBL-B-B_[Papilio_machaon]
Location
Bomo_Chr24(+):4955404-5036208      View in EpiBrowser
Location in the cell
Nuclear   Reliability : 3.833
 

Sequence

CDS
ATGGCGTTGAAGACAACCATAGATCTGACATGTAACGATTTCATATCGAACTTTGAATTTGACGTTTTCACGAGGCTCTTCCAGCCCTGGAGTACGCTGTTACGAAACTGGCAGCTACTTGCCGTGACGCATCCGGGTTACGTCGCCTTCCTTACGTACGACGAAGTCAAAGCGAGACTGCAGAAGTACATACACAAAGCCGGGAGCTACGTCTTCAGATTATCGTGCACAAGATTAGGGCAATGGGCCATAGGTTACGTGACAGCCGACGGTGAGATCCTACAGACGATACCTCAGAACAAGAGTTTGGTGCAGGCGCTCTTAGACGGGTATCGGGAAGGATTCTACTTATATCCTGACGGTCGAGATACGAATCCCGATTTGAGTAGCGCCATCATATCGCCCGCCGAGGATCACATCACAGTAACCCAAGAGCAATACGAGTTGTACTGCGAAATGGGCAGCACGTTCCAGCTTTGCAAGATATGCGCCGAAAACGACAAGGACATCAGAATAGAGCCGTGCGGGCATCTCTTGTGCACTCCCTGTCTCACTGCGTGGCAAATTGATTCCGAAGGGCAGGGTTGTCCGTTCTGCAGAGCCGAGATAAAGGGAACCGAGCAGGTCGTCGTGGACGCGTTCGTGCCGCCGCGCCCGCCCAACACCACGTCCGAGGCCAAGAATCCAAAGCCAACGGTAAAAGCGGTCTCTTCGAACTCCTCTGGATCGTCAGGCTCCTCCGGATGCAATGGATCGAGTTCGGACGGTGCCGGCTCCGGTAACGCGGCCAACGGCTGGTCGTCCAGGAGCGCGGCCACCTTCAACGGTCTCGCCGACGACATCGACGACGGAGAGGACTGGGCCGAATTCAACGCTGCGACGTCTACGATAGACGCGTTACGTCCGTCTGTCCGATCGCCCGGTGCGTCCCCGCGACACTCCCCCCGCGCGTCCCGCCGCACCCCCGCGCCCGCAGAGAACGCGTACGGGGAACTCAGGGCCCCCCCTCTGCCCCCGCGGAAGAGCCTCTCGCCCGCCGAACCGGCTATCGCGGCCGCGTCTAGTGTACAAGACATAGCTACTGCTAGCTCGTTGGAGCCCAAGAGGAGATCGTCTTTAGAGCCAGAACCTGACGCCCGGCATCGTTTGACATCCATCATAACAGGGTCCACGGAAACAATCACCGGTGTCATTGACACAAGACACGAGACTCCACCTGACCCACGTGCCTTCGAGAAGCCACGAAGGGCTTGCACCCCTCAGTCTAACAGCCGACCTCTCCCGGCCCCGCCCCCCGAGAGACCCGCAGACGACCGGCCCCCCTTAACGGAACGCAACGCCCCCGACCGACCAGAAAAACAAGAGAAACCGGATAATCGGCAACCGGAAACCCGACATCCGGACCGAATGCTAATACCCGAAAGGGTTCCTAACGACAGACACCAAGAGCTCCCCAGGCCTCCGGATAGAACGGATAAACCTGACAGAATACAATCGCAAGATCGCTTAGAACGAGCGCACACTTCGCTGGAGAAGCCCGGTAATACTGAAACCAGGTATTACGAGAGGGAGGTTAGGGCTCCTCCCAGACAGAGGTCGTTGCCAGCCAGTACGAGTAGCAGCATGGATCAGCCGACAAAGTCGACCACGATGCCGAAGTTCCCTTCGGAGGACGTGAAGGATCCGCCATACGAAAATGTAGGCGTCGAGAAAAACGAATTGGCCGTGGCACCAAAGAAAATAAACCCTCTAACCCATGACAAGCACGGTCGCAAGTACGGAGACAATGTCTCGTATGAAAACATTAATTTGGACTATATAGCGCGGCTGGTGGGCGAGGGTTATCCCAAAGAAATCGTGGTCCGCGCTCTGGGCATTACGAGAAACGACCTGGAAATGGCCTGCGACATCCTACACGAATTCGGATCTAAAGCGACCAATAAATGCTAG
Protein
MALKTTIDLTCNDFISNFEFDVFTRLFQPWSTLLRNWQLLAVTHPGYVAFLTYDEVKARLQKYIHKAGSYVFRLSCTRLGQWAIGYVTADGEILQTIPQNKSLVQALLDGYREGFYLYPDGRDTNPDLSSAIISPAEDHITVTQEQYELYCEMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTAWQIDSEGQGCPFCRAEIKGTEQVVVDAFVPPRPPNTTSEAKNPKPTVKAVSSNSSGSSGSSGCNGSSSDGAGSGNAANGWSSRSAATFNGLADDIDDGEDWAEFNAATSTIDALRPSVRSPGASPRHSPRASRRTPAPAENAYGELRAPPLPPRKSLSPAEPAIAAASSVQDIATASSLEPKRRSSLEPEPDARHRLTSIITGSTETITGVIDTRHETPPDPRAFEKPRRACTPQSNSRPLPAPPPERPADDRPPLTERNAPDRPEKQEKPDNRQPETRHPDRMLIPERVPNDRHQELPRPPDRTDKPDRIQSQDRLERAHTSLEKPGNTETRYYEREVRAPPRQRSLPASTSSSMDQPTKSTTMPKFPSEDVKDPPYENVGVEKNELAVAPKKINPLTHDKHGRKYGDNVSYENINLDYIARLVGEGYPKEIVVRALGITRNDLEMACDILHEFGSKATNKC

Summary

Uniprot
A0A3S2PFH6   A0A2W1BFY4   A0A2H1WED3   A0A2A4JSK8  
Pubmed
28756777   
EMBL
RSAL01000055    RVE49955.1    KZ150168    PZC72635.1    ODYU01008085    SOQ51387.1    + More
NWSH01000757    PCG74390.1   
Proteomes
UP000283053    UP000218220   
Pfam
PF02762   Cbl_N3        + More
PF02761   Cbl_N2
Interpro
IPR017907   Znf_RING_CS        + More
IPR039520   CBL-B_RING-HC       
IPR009060   UBA-like_sf       
IPR014742   Adaptor_Cbl_SH2-like       
IPR036860   SH2_dom_sf       
IPR013083   Znf_RING/FYVE/PHD       
IPR024159   Cbl_PTB       
IPR015940   UBA       
IPR014741   Adaptor_Cbl_EF_hand-like       
IPR001841   Znf_RING       
IPR011992   EF-hand-dom_pair       
IPR024162   Adaptor_Cbl       
SUPFAM
SSF47473   SSF47473        + More
SSF55550   SSF55550       
SSF46934   SSF46934       
Gene 3D
3.30.40.10     3.30.505.10    
CDD
cd09920  SH2_Cbl-b_TKB
 cd16709  RING-HC_Cbl-b
ProteinModelPortal
A0A3S2PFH6   A0A2W1BFY4   A0A2H1WED3   A0A2A4JSK8  
PDB
4A4C     E-value=1.07349e-105,     Score=982

Ontologies

KEGG
101740182    K04707 E3 ubiquitin-protein ligase CBL [EC:2.3.2.27] | (RefSeq) E3 ubiquitin-protein ligase CBL-B-B
PATHWAY
04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)
04144    Endocytosis - Bombyx mori (domestic silkworm)
GO
GO:0004842   GO:0023051   GO:0001784   GO:0005509   GO:0005515   GO:0008270   GO:0006816   GO:0016021   GO:0005507   GO:0004713   GO:0016491   GO:0015930  
PANTHER
PTHR23007  

Topology

Length:
649
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.09474
Exp number, first 60 AAs:
0.07702
Total prob of N-in:
0.00506
outside
1  -  649
 
 

Population Genetic Test Statistics

Pi
231.2703
Theta
159.518899
Tajima's D
1.529016
CLR
0.172289
CSRT
0.793710314484276
Interpretation
Uncertain
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