Gene

KWMTBOMO14351  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008120

Annotation

thioredoxin-like_protein_[Bombyx_mori]

Location

Bomo_Chr24(-):2782202-2800019      View in EpiBrowser

Full name

Thioredoxin       + More
Thioredoxin-2      

Location in the cell

Cytoplasmic   Reliability : 2.425

CDS

ATGTCCATTCACATCAAAGATTCCGACGACCTGAAGACAAGGCTGGCGGAAGCAGGCGACAAGCTCGTCGTGATCGACTTCATGGCGACCTGGTGCGGACCGTGCAAGATGATCGGGCCTAAACTGGACGAGATCGCCGCCGAAATGTCAGATTCCATCGTCGTTGTGAAGGTGGACGTTGATGAGTGCGAGGACATCGCCAGCGAGTACAACATTAACTCGATGCCGACGTTCGTCTTCGTTAAGAATGGCAAGAAACTGGACGAATTCTCTGGCGCTAACGTCGACAAACTCAAAACAACTATCCTTAAACACAAGTAA

Protein

MSIHIKDSDDLKTRLAEAGDKLVVIDFMATWCGPCKMIGPKLDEIAAEMSDSIVVVKVDVDECEDIASEYNINSMPTFVFVKNGKKLDEFSGANVDKLKTTILKHK

Description

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1 (By similarity).

Similarity

Belongs to the thioredoxin family.

Keywords

Disulfide bond   Electron transport   Redox-active center   Transport  

Feature

chain  Thioredoxin

Uniprot

A0FDR1   A0A0Y0BMD0   I4DMF1   A0A0N1PIJ3   I4DIU1   Q9U515   + More
S4PE71   A0A2H1VFV3   A0A075ML71   A0A3G1T1C0   A0A3B0ERN4   R4IT65   A0A0A0V7S1   A0A0K8SMS3   A0A2U6SP18   A0A3G5MYX7   A0A212EIZ1   E1XUQ3   K7IVP5   A0A1W4XUY2   A0A1Y1LWM6   A0A232F2J5   S4T697   M1KY63   A0A0J7KHK4   B4JCE8   A0A088AAY9   J3JX78   A0A0P4VTK5   R4G8I0   F4WNF4   A0A3L8E1L9   A0A0T6BD75   A0A2A3EF18   A0A224Y186   A0A069DNB4   A0A023FCX9   E2BFK3   E2J7F4   A0A0V0G3P6   D2A4J1   B4KH18   A0A158NW60   B4M9H2   A0A067QZQ7   A0A026W073   A0A0A9WXZ7   A0A1D2NA26   A0A1S3DQ54   A0A151IM69   L0ASR7   B3MUX0   A2I3V9   A0A154PDZ5   B4MTL8   A0A1B6HTH0   B0WX61   R4WMN1   A0A1Q3FDA4   A0A1B6GKE4   A0A1S3DNH4   A0A3B0KIU5   A0A226EN42   A0A0L0BL29   A0A0N0BE99   S6BTN7   Q1W2C2   A0A1I9WLE9   A0A1W4XKS3   A0A1J1HWR6   A0A1A9V9M9   A0A034WG58   A0A0C9RZK8   T1E2P3   Q29NA8   B4NY60   Q6XHI1   A0A1A9W009   A0A0A1XK21   A0A0K8TPJ4   A0A1W4XKD9   A0A1A9XGW6   A0A1B0A4Y1   A0A1W4VI52   A0A0K8VM22   T1PH17   L7XAL0   A0A1B0BUX0   B3N8G1   A0A182MJ83   D0EFL3   A0A0K8TIH6   T1J1M0   A0A182TWX3   A0A182XCJ3   Q9NGZ1   A0A182IDX3   A0A336KZF1   B4HW82   B4Q7U5  

Pubmed

22651552    26354079    10620045    23622113    28756777    25542738    + More
30410444    22118469    22844539    20075255    28004739    28648823    23747404    17994087    22516182    23537049    27129103    21719571    30249741    26334808    25474469    20798317    18362917    19820115    21347285    24845553    24508170    25401762    26823975    27289101    23691247    26108605    27538518    25348373    24330624    15632085    17550304    14525923    25830018    26369729    25315136    23231853    12364791    14747013    17210077    22936249   

EMBL

DQ985602    EF198474    ABJ97191.1    ABM92269.1    KT454797    AMB21289.1    + More
AK402469    BAM19091.1    KQ460254    KPJ16342.1    AK401209    KQ459386    BAM17831.1    KPJ01158.1    AF117573    AAF16695.1    GAIX01003286    JAA89274.1    ODYU01002074    SOQ39124.1    KJ744039    AIF80134.1    MG846928    AXY94780.1    RBVL01000250    RKO10120.1    JQ744277    KZ150334    AGC39043.1    PZC71336.1    KM358526    AIW61834.1    GBRD01011410    JAG54414.1    KR811232    ANC55854.1    MH443001    AYX41553.1    AGBW02014547    OWR41449.1    FR681573    CBW45298.1    GEZM01047826    JAV76730.1    NNAY01001213    OXU24710.1    JX844649    JX844650    AFU83101.1    JR050256    KC176775    AEY61212.1    AGF33352.1    LBMM01007470    KMQ89714.1    CH916368    EDW03102.1    APGK01036673    BT127846    KB740941    KB632225    AEE62808.1    ENN77622.1    ERL90248.1    GDKW01000742    JAI55853.1    ACPB03000284    GAHY01000937    JAA76573.1    GL888237    EGI64147.1    QOIP01000001    RLU26353.1    LJIG01001691    KRT85249.1    KZ288267    PBC30074.1    GFTR01001684    JAW14742.1    GBGD01003579    JAC85310.1    GBBI01000009    GEMB01003595    JAC18703.1    JAR99622.1    GL448037    EFN85525.1    HP429372    ADN29872.1    GECL01003525    JAP02599.1    KQ971344    EFA05230.1    CH933807    EDW12229.1    ADTU01027820    CH940654    EDW57848.1    KK852808    KDR16041.1    KK107522    EZA49305.1    GBHO01032196    GBRD01000431    GDHC01003309    JAG11408.1    JAG65390.1    JAQ15320.1    LJIJ01000125    ODN02097.1    KQ977063    KYN05969.1    JX879125    AFZ78678.1    CH902624    EDV33035.1    EF070462    ABM55528.1    KQ434886    KZC10082.1    CH963852    EDW75457.1    GECU01029740    JAS77966.1    DS232158    EDS36322.1    AK416901    BAN20116.1    GFDL01009508    JAV25537.1    GECZ01006852    JAS62917.1    OUUW01000010    SPP85686.1    LNIX01000002    OXA59052.1    JRES01001704    KNC20752.1    KQ435844    KOX71264.1    AB842145    BAN67602.1    DQ445505    GEBQ01031306    ABD98743.1    JAT08671.1    KU932333    APA33969.1    CVRI01000020    CRK90569.1    GAKP01004381    JAC54571.1    GBYB01013561    JAG83328.1    GALA01000509    JAA94343.1    CH379060    EAL33434.1    CM000157    EDW88662.1    AY232202    AAR10225.1    GBXI01003409    JAD10883.1    GDAI01001286    JAI16317.1    GDHF01012382    JAI39932.1    KA647430    AFP62059.1    JQ864188    AGC96525.1    JXJN01020958    CH954177    EDV58384.1    AXCM01000826    GQ479801    ACX30746.1    GBRD01000428    JAG65393.1    JH431789    AF236124    AAAB01008980    AAF68382.1    EAA14367.3    APCN01004535    UFQS01001105    UFQT01001105    UFQT01002506    SSX09023.1    SSX28934.1    SSX33601.1    CH480818    EDW52277.1    CM000361    CM002910    EDX04377.1    KMY89293.1   

Proteomes

UP000053240    UP000053268    UP000276569    UP000007151    UP000002358    UP000192223    + More
UP000215335    UP000036403    UP000001070    UP000005203    UP000019118    UP000030742    UP000015103    UP000007755    UP000279307    UP000242457    UP000008237    UP000007266    UP000009192    UP000005205    UP000008792    UP000027135    UP000053097    UP000094527    UP000079169    UP000078542    UP000007801    UP000076502    UP000007798    UP000002320    UP000268350    UP000198287    UP000037069    UP000053105    UP000183832    UP000078200    UP000001819    UP000002282    UP000091820    UP000092443    UP000092445    UP000192221    UP000095301    UP000092460    UP000008711    UP000075883    UP000075902    UP000076407    UP000007062    UP000075840    UP000001292    UP000000304   

PRIDE

A0FDR1    Q6XHI1   

Pfam

PF00085   Thioredoxin

Interpro

IPR013766   Thioredoxin_domain        + More
IPR036249   Thioredoxin-like_sf       
IPR005746   Thioredoxin       
IPR017937   Thioredoxin_CS       

SUPFAM

SSF52833   SSF52833       

ProteinModelPortal

A0FDR1   A0A0Y0BMD0   I4DMF1   A0A0N1PIJ3   I4DIU1   Q9U515   + More
S4PE71   A0A2H1VFV3   A0A075ML71   A0A3G1T1C0   A0A3B0ERN4   R4IT65   A0A0A0V7S1   A0A0K8SMS3   A0A2U6SP18   A0A3G5MYX7   A0A212EIZ1   E1XUQ3   K7IVP5   A0A1W4XUY2   A0A1Y1LWM6   A0A232F2J5   S4T697   M1KY63   A0A0J7KHK4   B4JCE8   A0A088AAY9   J3JX78   A0A0P4VTK5   R4G8I0   F4WNF4   A0A3L8E1L9   A0A0T6BD75   A0A2A3EF18   A0A224Y186   A0A069DNB4   A0A023FCX9   E2BFK3   E2J7F4   A0A0V0G3P6   D2A4J1   B4KH18   A0A158NW60   B4M9H2   A0A067QZQ7   A0A026W073   A0A0A9WXZ7   A0A1D2NA26   A0A1S3DQ54   A0A151IM69   L0ASR7   B3MUX0   A2I3V9   A0A154PDZ5   B4MTL8   A0A1B6HTH0   B0WX61   R4WMN1   A0A1Q3FDA4   A0A1B6GKE4   A0A1S3DNH4   A0A3B0KIU5   A0A226EN42   A0A0L0BL29   A0A0N0BE99   S6BTN7   Q1W2C2   A0A1I9WLE9   A0A1W4XKS3   A0A1J1HWR6   A0A1A9V9M9   A0A034WG58   A0A0C9RZK8   T1E2P3   Q29NA8   B4NY60   Q6XHI1   A0A1A9W009   A0A0A1XK21   A0A0K8TPJ4   A0A1W4XKD9   A0A1A9XGW6   A0A1B0A4Y1   A0A1W4VI52   A0A0K8VM22   T1PH17   L7XAL0   A0A1B0BUX0   B3N8G1   A0A182MJ83   D0EFL3   A0A0K8TIH6   T1J1M0   A0A182TWX3   A0A182XCJ3   Q9NGZ1   A0A182IDX3   A0A336KZF1   B4HW82   B4Q7U5  

PDB

5DBQ     E-value=2.24231e-38,     Score=392

KEGG

778509    K03671 thioredoxin 1 | (RefSeq) thioredoxin-like protein

GO

GO:0015035   GO:0045454   GO:0005623   GO:0006662   GO:0005634   GO:0050832   GO:0006979   GO:0008340   GO:0004674   GO:0005488   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

Length:

106

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01416

Exp number, first 60 AAs:

0.01416

Total prob of N-in:

0.39728

outside

1  -  106

 

 

Pi

280.440704

Theta

163.666554

Tajima's D

2.641762

CLR

0.097928

CSRT

0.96025198740063

Interpretation

Uncertain