Gene

KWMTBOMO14348

Pre Gene Modal

BGIBMGA008201

Annotation

PREDICTED:_protein_lines_[Papilio_machaon]

Location

Bomo_Chr24(+):2735820-2738764      View in EpiBrowser

Full name

Protein lines      

Location in the cell

Nuclear   Reliability : 3.855

CDS

ATGGTTTTGAGAGGGCAGCTGTGCAATCCTCATACAAATGAAGCTATGGCTTCTGATCAACCCGTCAAGAAGAAACAGAGAATCGACGCTCCTGATATTGACGAAGGCAGTGACCGATCCGCCGAGGATGTCCTGACCGACATCTTCGAAAGCGAAACACCCGCCGAAACCTCTGAAGAATTCCCAACAAGGAATGGAGAGTCCCCAGACAGTGGTACTGTTAGTGAAGATGCTGTCGACTGTTCTAGCATATTGAGGCTCCAGAGTGATTCTGGTGTGGAAATCTTACCGTCGTGTTCAAATACAAACTCACAGTGGAATTCTGAAAATGACAAATTACTATCTGAACTGAGGTTACTCCAAAATAACCTAATCGGGCAGTGTTTATGTCAATTTGATGAAAATATTGTTACACAACTATTTGATCGACAATTGAATATTTCAACATGGCCTTTGACGTCTTCCCTGACTTATCTCTCAACTATGCAGCTGATGTTCGACATATATCTCAAACAAAATGGTACAGGAACAATATGTTCAAAAGTAATGCAAGCATGTGACTTACTAGTACGTAATAGACATGATTGGATAACTGAGGTTGTTGAATTAGCCGACCACAAAAGTAAATACATCACATTCATAGCCAGTAGAGTATTAGCTACATTTTTGATAGTATCAAAAGACACAGTAGATGAAAACTGGTTACAACAGATAGCTGAAAATATTTATTTATTTGATAGAATCAACAGAATTACAGTACAAAAGATAAATTTTACTCTAGATATAATTAAAAGGATAGTGGAGTGGAAAGATGTTGAACAGCATCCTTTGGAAGACAGTAACTACATTAACACACCAAGTAATACTTATGTTCAAGAAGACAATCCATTTAGAAGTAATATAGGCTATTCTAATAGTACAGAAGGCCCATCAAGTTCACATAACAATTTACACAATGAATTTTCAAATTTACACACCAATAGCACTCCGTCGACATCAAATGAACAGGCGGAGAAGCCCGTAATCTTTAAACTACAAGAACCAGTATTAAAATTAGACTCTAATGAGGAAAGGCAGGAGATGGAGCATTCTCCTGAAACACCAGCTGAAAGAATAGAAAGAGTCAATGAGCATGGTTGTGTGACTGTCATGCTGACAGATTCTGAATCTTTTGACACTTCACACATAAAGTGTTTAACGATAAAAACCTTGGAGCACCACTGGCCGATTCTTGTGAAAAACATGAAACTTTTACTACTAAGGTACCTGAATTTAGCTAATGCTGAAAATTGTATATTAACATTTTTTTCTTTATGGGAGAACATCATAAGTGTTAAAGCGAATCTCTCGATAATCGATACAAAACCATTTTATGCAGACCTTCAGAGCTTTGTTGATTTACTAAGGAATACAATGTTGCCGAGTTTAATATACACACATTTGTTAAGTTTATTCAATGAGGTTCTATGTTATGGTTCGACATTAGCTTTACAAGATATTTTACCCGAAGAAATATGCAGCTTAGCTCACTCAATAGTGAGATTTGTTAAAGATTTTAGGTTATTAAATAATGTAAGAGTACAAAATAGTAGGAGTGGTTTTGGCTTTTTAGGGCACGACTGTAGGGTTGTAACGGACTATTCCTTAGGGCCTGAAGTATTACCCTTATCATCCTCGATACAGTTAGTAGACCAGAGTTACGGAGATGATGATATTGATCAACAATCACAGTCAGAGGTAGACAAGACTATGTTGCAAAGAATGTCTTTGCTCGTGCTCAAATCTATAGCTGTCACAGTCAAAGAGATGAGATGTGATTCGTCAGACAGTTCAATAGATTCATCAGACTACAATGCTATACAAGACATGCAGATTGTAGAGAGGTCAATACGGGATGTATTGAAGAAATTAGATGTTTTTATACGGAATAGTTTAGATTTCCATCCAGAAACACCATTCACAAAAATGTTAATACATTTGTTTAGTGAGCAAGACGATTATCTAATAGAATCAATGGTTTGTACTTTGGATATTACAGTTGGCATCGTCTATAGGAATTCCGTGTATCCAGACTTAATACCTATGTTGAATCCGATTTCATCGTTCATAGAATTTCTTAAGGTTGTTTCGCACGACAGTGATGTTCTGTTGGATTATTTGGTAAGTAATGAGACATGTTTTCTGCTATACTTACTAAGGTTTCTTAAATATGTAAGAAGGAACTGGCCTAAGTTTCTTGATACGTGCCAGCAGACTGATGCGGGAGGCACGAGAGGCCTAGACGACACAATGAGAGTCTTAATACGATTACGTTTACAAATAAGTCGATTAGTATCAAAATCACTCTTCCCATACAACATAAGTCCTGTTCTGAGATTGTTGGAGGTTTCTGAAAGCTTGTATGAAGGTAACGAATTTAGCTGA

Protein

MVLRGQLCNPHTNEAMASDQPVKKKQRIDAPDIDEGSDRSAEDVLTDIFESETPAETSEEFPTRNGESPDSGTVSEDAVDCSSILRLQSDSGVEILPSCSNTNSQWNSENDKLLSELRLLQNNLIGQCLCQFDENIVTQLFDRQLNISTWPLTSSLTYLSTMQLMFDIYLKQNGTGTICSKVMQACDLLVRNRHDWITEVVELADHKSKYITFIASRVLATFLIVSKDTVDENWLQQIAENIYLFDRINRITVQKINFTLDIIKRIVEWKDVEQHPLEDSNYINTPSNTYVQEDNPFRSNIGYSNSTEGPSSSHNNLHNEFSNLHTNSTPSTSNEQAEKPVIFKLQEPVLKLDSNEERQEMEHSPETPAERIERVNEHGCVTVMLTDSESFDTSHIKCLTIKTLEHHWPILVKNMKLLLLRYLNLANAENCILTFFSLWENIISVKANLSIIDTKPFYADLQSFVDLLRNTMLPSLIYTHLLSLFNEVLCYGSTLALQDILPEEICSLAHSIVRFVKDFRLLNNVRVQNSRSGFGFLGHDCRVVTDYSLGPEVLPLSSSIQLVDQSYGDDDIDQQSQSEVDKTMLQRMSLLVLKSIAVTVKEMRCDSSDSSIDSSDYNAIQDMQIVERSIRDVLKKLDVFIRNSLDFHPETPFTKMLIHLFSEQDDYLIESMVCTLDITVGIVYRNSVYPDLIPMLNPISSFIEFLKVVSHDSDVLLDYLVSNETCFLLYLLRFLKYVRRNWPKFLDTCQQTDAGGTRGLDDTMRVLIRLRLQISRLVSKSLFPYNISPVLRLLEVSESLYEGNEFS

Description

Has a dual role as a segment polarity protein and as a modulator of the Abd-B protein. Required for Abd-B to activate the transcription of genes (including ems, cut and sal) that are involved in posterior spiracle morphogenesis. Also required for Abd-B to form an eighth abdominal denticle belt. Acts in a hierarchy downstream of drm and upstream of bowl during foregut and hindgut patterning and morphogenesis. Involved in cell rearrangement during elongation of the embryonic hindgut. Required to regulate expression of embryonic hindgut patterning genes in order to establish the large intestine and at least some rectum, and to repress small intestine fate. Required for late wingless (wg)-dependent cell fate specification in the dorsal embryonic epidermis. Acts in concert with wg to regulate expression of wg itself and also to regulate wg-target genes. May have a role in ventral epidermal patterning, independent of wg signaling.

Subunit

Interacts with drm.

Similarity

Belongs to the protein lines family.

Keywords

Activator   Complete proteome   Cytoplasm   Developmental protein   Nucleus   Reference proteome   Repressor   Segmentation polarity protein   Transcription   Transcription regulation   Wnt signaling pathway  

Feature

chain  Protein lines

Uniprot

H9JFA4   A0A2H1X3E2   A0A2A4JAG4   A0A2W1BI29   A0A0N1IPD0   A0A194Q853   + More
A0A3S2NVK4   A0A0L7LKW8   A0A212ELW3   T1PIM9   A0A1I8N2W9   A0A0L0CM74   A0A1I8NS49   B4JVE9   B4P3E1   A0A1B0G712   B4LNN8   B3N846   A0A1B0AGB6   A0A1A9XME5   A0A1B0B1X8   B3ME97   B4HSB2   A0A1W4UXE6   Q28Y80   B4MIZ1   Q9V4Z9   A0A3B0IZM6   A0A1A9V1U4   A0A0M3QUH4   Q2XY64   A0A0J9R8K2   Q2XY63   Q2XY65   Q2XY66   Q2XY68   A0A1J1HJ52   Q16SZ3   B4QGN1   A0A0P6JSE3   A0A1S4FQA0   A0A182G713   A0A182SMS6   A0A182UUG2   A0A182YIV5   A0A182NV51  

Pubmed

19121390    28756777    26354079    26227816    22118469    25315136    + More
26108605    17994087    17550304    18057021    15632085    10837029    10731132    12537572    8620835    9477325    11784087    12117814    14568103    16120803    22936249    17510324    26999592    26483478    25244985   

EMBL

BABH01027029    ODYU01013158    SOQ59851.1    NWSH01002130    PCG69075.1    KZ150334    + More
PZC71333.1    KQ460601    KPJ13808.1    KQ459386    KPJ01170.1    RSAL01000055    RVE49911.1    JTDY01000795    KOB75851.1    AGBW02013982    OWR42451.1    KA648514    AFP63143.1    JRES01000195    KNC33380.1    CH916375    EDV98417.1    CM000157    EDW89414.1    CCAG010003761    CH940648    EDW60108.1    KRF79247.1    CH954177    EDV59459.1    JXJN01007364    CH902619    EDV36503.1    CH480816    EDW47007.1    CM000071    EAL26085.2    CH963719    EDW72080.1    AF272358    AE013599    BT021378    AAF59024.1    AAF76228.1    AAX33526.1    OUUW01000001    SPP73884.1    CP012524    ALC40639.1    DQ138798    ABA86404.1    CM002911    KMY92371.1    DQ138799    ABA86405.1    DQ138797    ABA86403.1    DQ138795    DQ138796    ABA86401.1    ABA86402.1    DQ138794    ABA86400.1    CVRI01000006    CRK88045.1    CH477663    EAT37565.1    CM000362    EDX06256.1    GDUN01000477    JAN95442.1    JXUM01241426    JXUM01241427    JXUM01241428    JXUM01241429    JXUM01241430    KQ635217    KXJ62510.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000037510    + More
UP000007151    UP000095301    UP000037069    UP000095300    UP000001070    UP000002282    UP000092444    UP000008792    UP000008711    UP000092445    UP000092443    UP000092460    UP000007801    UP000001292    UP000192221    UP000001819    UP000007798    UP000000803    UP000268350    UP000078200    UP000092553    UP000183832    UP000008820    UP000000304    UP000069940    UP000249989    UP000075901    UP000075903    UP000076408    UP000075884   

PRIDE

H9JFA4    Q9V4Z9    Q2XY68   

Pfam

PF14695   LINES_C        + More
PF14694   LINES_N

Interpro

IPR024875   Protein_Lines        + More
IPR032794   LINES_N       
IPR029415   Lines_C       

ProteinModelPortal

H9JFA4   A0A2H1X3E2   A0A2A4JAG4   A0A2W1BI29   A0A0N1IPD0   A0A194Q853   + More
A0A3S2NVK4   A0A0L7LKW8   A0A212ELW3   T1PIM9   A0A1I8N2W9   A0A0L0CM74   A0A1I8NS49   B4JVE9   B4P3E1   A0A1B0G712   B4LNN8   B3N846   A0A1B0AGB6   A0A1A9XME5   A0A1B0B1X8   B3ME97   B4HSB2   A0A1W4UXE6   Q28Y80   B4MIZ1   Q9V4Z9   A0A3B0IZM6   A0A1A9V1U4   A0A0M3QUH4   Q2XY64   A0A0J9R8K2   Q2XY63   Q2XY65   Q2XY66   Q2XY68   A0A1J1HJ52   Q16SZ3   B4QGN1   A0A0P6JSE3   A0A1S4FQA0   A0A182G713   A0A182SMS6   A0A182UUG2   A0A182YIV5   A0A182NV51  

KEGG

101741796    K22533 protein Lines | (RefSeq) protein lines

GO

GO:0005634   GO:0005737   GO:0045944   GO:0009946   GO:0048619   GO:0035277   GO:0009880   GO:0048617   GO:0008544   GO:0035220   GO:0016055   GO:0007442   GO:0007440   GO:0007367  

PANTHER

PTHR16057  

Subcellular location

Cytoplasm  
Nucleus  

Length:

807

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.32715

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00114

outside

1  -  807

 

 

Pi

254.284316

Theta

219.298161

Tajima's D

0.569335

CLR

20.535594

CSRT

0.538823058847058

Interpretation

Uncertain