Gene

KWMTBOMO14319

Pre Gene Modal

BGIBMGA008188

Annotation

PREDICTED:_probable_beta-hexosaminidase_fdl_[Bombyx_mori]

Location

Bomo_Chr24(+):1868831-1871175      View in EpiBrowser

Full name

Beta-hexosaminidase      

Location in the cell

PlasmaMembrane   Reliability : 1.857

CDS

ATGGGACCACAGCTTTGGCCTTACCCGATTGGCTATACGTTGTTCAGTAAAAATTTGGTAGCTATGTCGATCCTAAAATTGGAATACAAATTTCAATCGTTACCTTCAGAGAACGTGCATCGGCATTTAGCTGAAGCGTTTAAACTCTTCATTGGAGATTTAGCTCGATTGGAAAAGATAGGCAGAGAAATGAAAAACGGCACCTGTGATTTACCCGTCAAAAAGATGAATATTATTATAGATATCGAAACAGATCCCGATCCAAGATTGAGACTGAATACTGACGAAGCGTACACTATTAGTGTTAATAGCAATTTTGATTTTATTACCATACATTTAAGTTCCTCGTCTTTCTGTGGAGCTAGACATGGCTTGGAGACATTGAACCAGATGATTTTACTAGATCAACTGACCGGCTATTTGATAACTTTGTCGCATATTATTGTAAAGGACGCGCCAAGTCATAAATATAGAGGACTCATGATTGACACAGGAAGAAATTATATACCGATGCCAGATTTAATGAAAACTATTGATACAATGGCCGCTTGCAAATTAAATACATTTCACTGGAGGATATCCGATGTAACGAGCTTTCCGTTGCTTTTACCCAAGCTAAAAGAATTATTTGAGTTCGGTGCTTATGATAGAGCTTTGGTTTATACGAGAGCTGATGTGAAAGCTTTAGTGACGAGGGCTAAAGTTAGGGGGATTAGAGTATTGATTGAAGTGGCTGCACCGGGGCCGGTTGGACGACCTTGGTTTTGGCACAGCGAAGCGACTTGCCCGGCCAAAAATGCGAATTACACGTGCGATAACTTATTGTGTCTTAGATTAAATATGAGAGAGTCCATTTTTGATATATTACAATTAATATACGCCGAAATCATTGCACTCACTGAAGTGGACGATATATTCCATTTAAGTGATGGAGTATTCACAATGATCAATTGCTTTTCGTTGATTGAGGATAGAGATGGGTTTTTAGATAAAGCGCTGAATAGGCTAAGAATGGCCAATAAAGGCTTCATGCCGAAATTACCCATAGTCTGGTATACGAAACATCTGACCAGGACTCTTGAGGCGAAAACGTGGGAGCATTTGGGAGTGCAGCTTTATAAGTGGAACCCCGATTCTGGAGATTATTTGGGAACGTTTCGCGTGATTCATTCAAACAAATGGGATCTGTCGTGCGAAATGCGGAAACAGAGATGTTATAAATACCGGACTTGGCAAGGAATGTACTCGTGGACATCTTGGCGAAACATCGACGTGTTCACGATAGAAGGTGGAGAGGCAGTTCTTTGGACCGATTTTGTAGATTCAGGAAATCTTGATTATCACCTGTGGCCACGTGCTGCCGCAGTAGCCGAGAGACTGTGGTCAGATATAATAGCGAACACTACACCAAATCCTGAAGTCTACGTGAGATTAGATTACCATAGGTAA

Protein

MGPQLWPYPIGYTLFSKNLVAMSILKLEYKFQSLPSENVHRHLAEAFKLFIGDLARLEKIGREMKNGTCDLPVKKMNIIIDIETDPDPRLRLNTDEAYTISVNSNFDFITIHLSSSSFCGARHGLETLNQMILLDQLTGYLITLSHIIVKDAPSHKYRGLMIDTGRNYIPMPDLMKTIDTMAACKLNTFHWRISDVTSFPLLLPKLKELFEFGAYDRALVYTRADVKALVTRAKVRGIRVLIEVAAPGPVGRPWFWHSEATCPAKNANYTCDNLLCLRLNMRESIFDILQLIYAEIIALTEVDDIFHLSDGVFTMINCFSLIEDRDGFLDKALNRLRMANKGFMPKLPIVWYTKHLTRTLEAKTWEHLGVQLYKWNPDSGDYLGTFRVIHSNKWDLSCEMRKQRCYKYRTWQGMYSWTSWRNIDVFTIEGGEAVLWTDFVDSGNLDYHLWPRAAAVAERLWSDIIANTTPNPEVYVRLDYHR

Catalytic Activity

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.

Similarity

Belongs to the glycosyl hydrolase 20 family.

Feature

chain  Beta-hexosaminidase

Uniprot

H9JF91   A0A2W1BL71   A0A0N1IH43   A0A0L7LDX4   A0A2A4ITA1   A0A212FFS2   + More
A0A2H1WLD1   A0A194QCN4   B1P868   D6PW84   A0A194QCU8   A0A3S2NQV5   A0A212FNK4   A0A0L7LFG8   A0A0L7KQB6   D3GGI7   E1CG96   D3GGI8   D3GGI9   H9J3A9   A0A2A4JAM6   A0A212F886   A0A0L7LKV0   A0A194QZT5   A0A2A4JIQ5   A0A194QE79   A0A0G2RLW6   A0A194QYW8   A0A2H1VA55   A0A1Y1MUX2   A0A154PQQ9   A0A232F8H7   K7INU6   A0A0A7NXB7   A5YVX6   A0A0L7QN95   A0A2A3ES46   A0A088ANY0   A0A1L8E264   J3JWB4   U4UHA8   A0A026VXS5   F4WC87   A0A3L8D4R7   E2AN60   A0A2P8Y7F7   A0A1B0CI79   A0A195BK61   A0A195FQK5   A0A158N9Y2   A0A195C5C4   A0A151XJZ2   A0A1W4WN94   A0A1W4WN20   A0A1W4WM34   A0A1W4WC04   A0A1B0AU39   E2BWS6   A0A0T6BB39   A0A0J7LBD6   A0A1A9ZAJ7   A0A2J7REG4   A0A067QJM1   B4H544   A0A0R3NQ30   A0A0R3NWB6   A0A0R3NVQ4   Q28X77   A0A195EKI6   B3MEN3   A0A310SG90   A0A0Q9XGJ7   B4KPZ8   A0A3B0JFG0   A0A3B0JKP9   A0A1B1TKD7   A0A1A9V255   A0A1A9XPJ4   A0A1B0BXA1   U4UGG0   A0A1Q3F2V3   A0A1J1I7Y3   A0A1J1I989   A0A1Q3F2U8   A0A1B0FDX0   A5YVX5   D6WA88   A0A1A9X4S7   B4N602   A0A0L0C5J2   A0A182GY98   B0WNY9   A0A0M4E7X0   A0A0P6IVH7   A0A0R1DWG8   B4P590   A0A0R1DQK7   A0A0J9RB23   B4QCX6   A0A0J9RB31  

EC Number

3.2.1.52

Pubmed

19121390    28756777    26354079    26227816    22118469    18303021    + More
20547376    28004739    28648823    20075255    25488985    18342252    18362917    19820115    22516182    23537049    24508170    21719571    30249741    20798317    29403074    21347285    24845553    17994087    15632085    26108605    26483478    26999592    17550304    22936249   

EMBL

BABH01026945    KZ149980    PZC75822.1    KQ460299    KPJ16149.1    JTDY01001544    + More
KOB73584.1    NWSH01007588    PCG62899.1    AGBW02008773    OWR52577.1    ODYU01009424    SOQ53838.1    KQ459386    KPJ01201.1    EU334747    ODYU01005953    ACA30398.1    SOQ47378.1    GU984637    ADF97235.1    KQ459185    KPJ03244.1    RSAL01000352    RVE42263.1    AGBW02005277    OWR55318.1    JTDY01001324    KOB74197.1    JTDY01007043    KOB65498.1    FJ695479    ACV89845.1    AB540233    BAJ20189.1    FJ695480    ACV89846.1    BABH01021699    BABH01021700    FJ695481    ACV89847.1    BABH01021684    NWSH01002205    PCG68909.1    AGBW02009781    OWR49928.1    JTDY01000705    KOB76153.1    KQ460949    KPJ10490.1    NWSH01001413    PCG71313.1    KPJ03250.1    KP000851    AJG44546.1    KPJ10484.1    ODYU01001276    SOQ37272.1    GEZM01019981    JAV89483.1    KQ435007    KZC13460.1    NNAY01000660    OXU27126.1    KJ786476    AIZ97749.1    EF592539    KQ971354    ABQ95985.1    EFA06836.2    KQ414860    KOC60039.1    KZ288193    PBC34036.1    GFDF01001338    JAV12746.1    BT127532    AEE62494.1    KB632326    ERL92397.1    KK107796    EZA47639.1    GL888070    EGI68067.1    QOIP01000013    RLU15380.1    GL441088    EFN65124.1    PYGN01000845    PSN40104.1    AJWK01013083    KQ976455    KYM85038.1    KQ981305    KYN42860.1    ADTU01009908    KQ978292    KYM95386.1    KQ982052    KYQ60598.1    JXJN01003514    GL451188    EFN79790.1    LJIG01002462    KRT84478.1    LBMM01000051    KMR05153.1    NEVH01004981    PNF39232.1    KK853284    KDR09002.1    CH479210    EDW32880.1    CM000071    KRT03108.1    KRT03107.1    KRT03109.1    EAL26439.2    KQ978739    KYN28753.1    CH902619    EDV35497.2    KQ770827    OAD52570.1    CH933808    KRG03902.1    EDW08100.1    OUUW01000001    SPP74050.1    SPP74049.1    KU522433    ANV82809.1    JXJN01022146    KB632345    ERL93064.1    GFDL01013164    JAV21881.1    CVRI01000043    CRK96299.1    CRK96298.1    GFDL01013165    JAV21880.1    CCAG010006435    EF592538    ABQ95984.1    KQ971312    EEZ98597.1    CH964154    EDW79791.2    JRES01000960    KNC26699.1    JXUM01097258    JXUM01097259    JXUM01097260    JXUM01097261    DS232017    EDS32008.1    CP012524    ALC40696.1    GDUN01000092    JAN95827.1    CM000158    KRJ99443.1    EDW90752.2    KRJ99444.1    CM002911    KMY93226.1    CM000362    EDX06787.1    KMY93230.1    KMY93227.1   

Proteomes

UP000005204    UP000053240    UP000037510    UP000218220    UP000007151    UP000053268    + More
UP000283053    UP000076502    UP000215335    UP000002358    UP000007266    UP000053825    UP000242457    UP000005203    UP000030742    UP000053097    UP000007755    UP000279307    UP000000311    UP000245037    UP000092461    UP000078540    UP000078541    UP000005205    UP000078542    UP000075809    UP000192223    UP000092460    UP000008237    UP000036403    UP000092445    UP000235965    UP000027135    UP000008744    UP000001819    UP000078492    UP000007801    UP000009192    UP000268350    UP000078200    UP000092443    UP000183832    UP000092444    UP000091820    UP000007798    UP000037069    UP000069940    UP000002320    UP000092553    UP000002282    UP000000304   

PRIDE

H9JF91    D3GGI7    E1CG96    D3GGI8    D3GGI9    H9J3A9    + More

Pfam

PF00728   Glyco_hydro_20        + More
PF14845   Glycohydro_20b2
PF01490   Aa_trans

Interpro

IPR029018   Hex-like_dom2        + More
IPR017853   Glycoside_hydrolase_SF       
IPR025705   Beta_hexosaminidase_sua/sub       
IPR029019   HEX_eukaryotic_N       
IPR015883   Glyco_hydro_20_cat       
IPR013057   AA_transpt_TM       

SUPFAM

SSF51445   SSF51445        + More
SSF55545   SSF55545       

Gene 3D

3.30.379.10    

ProteinModelPortal

H9JF91   A0A2W1BL71   A0A0N1IH43   A0A0L7LDX4   A0A2A4ITA1   A0A212FFS2   + More
A0A2H1WLD1   A0A194QCN4   B1P868   D6PW84   A0A194QCU8   A0A3S2NQV5   A0A212FNK4   A0A0L7LFG8   A0A0L7KQB6   D3GGI7   E1CG96   D3GGI8   D3GGI9   H9J3A9   A0A2A4JAM6   A0A212F886   A0A0L7LKV0   A0A194QZT5   A0A2A4JIQ5   A0A194QE79   A0A0G2RLW6   A0A194QYW8   A0A2H1VA55   A0A1Y1MUX2   A0A154PQQ9   A0A232F8H7   K7INU6   A0A0A7NXB7   A5YVX6   A0A0L7QN95   A0A2A3ES46   A0A088ANY0   A0A1L8E264   J3JWB4   U4UHA8   A0A026VXS5   F4WC87   A0A3L8D4R7   E2AN60   A0A2P8Y7F7   A0A1B0CI79   A0A195BK61   A0A195FQK5   A0A158N9Y2   A0A195C5C4   A0A151XJZ2   A0A1W4WN94   A0A1W4WN20   A0A1W4WM34   A0A1W4WC04   A0A1B0AU39   E2BWS6   A0A0T6BB39   A0A0J7LBD6   A0A1A9ZAJ7   A0A2J7REG4   A0A067QJM1   B4H544   A0A0R3NQ30   A0A0R3NWB6   A0A0R3NVQ4   Q28X77   A0A195EKI6   B3MEN3   A0A310SG90   A0A0Q9XGJ7   B4KPZ8   A0A3B0JFG0   A0A3B0JKP9   A0A1B1TKD7   A0A1A9V255   A0A1A9XPJ4   A0A1B0BXA1   U4UGG0   A0A1Q3F2V3   A0A1J1I7Y3   A0A1J1I989   A0A1Q3F2U8   A0A1B0FDX0   A5YVX5   D6WA88   A0A1A9X4S7   B4N602   A0A0L0C5J2   A0A182GY98   B0WNY9   A0A0M4E7X0   A0A0P6IVH7   A0A0R1DWG8   B4P590   A0A0R1DQK7   A0A0J9RB23   B4QCX6   A0A0J9RB31  

PDB

3S6T     E-value=1.65282e-45,     Score=461

KEGG

101745656    K20730 beta-hexosaminidase Fdl [EC:3.2.1.52] | (RefSeq) probable beta-hexosaminidase fdl

PATHWAY

00511    Other glycan degradation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005975   GO:0004563   GO:0016021   GO:0102148   GO:0008152   GO:0004553   GO:0008270   GO:0005488   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

Length:

482

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.19274

Exp number, first 60 AAs:

0.17515

Total prob of N-in:

0.00862

outside

1  -  482

 

 

Pi

138.105854

Theta

170.974785

Tajima's D

-0.506269

CLR

3.09089

CSRT

0.24348782560872

Interpretation

Uncertain