Gene

KWMTBOMO14301  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008141

Annotation

alpha-esterase_49_precursor_[Bombyx_mori]

Location

Bomo_Chr24(-):1211048-1214785      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

Cytoplasmic   Reliability : 2.588

CDS

ATGTCGGCTCGGAGACGTGTTCTTGTTGCTGTCCAAATTCTTTTATATTTGGTCAACGAAAGCCAAGGTTTGGCCAGAATTGACCCTCTGGTTGAGACCGAGCTGGGCCTGATCAAGGGTCTGAGGGCGAACGATGGGGACTACGCCATGTTCTTGGGTATACCCTTTGGAAAAGTCAACGCTAGCAATCCTTTTGGGGACGCAACGGCATATGGTAAATTTGATGGGGTATTAGAAGCTTACGATGATTCGGCGATATGCCCTCAAATTGACGAAGCCACTGGCGTCTACATTGGCACCATAGATTGTCTACATCTCAACGTATACGTTCCCCCTTCAGCGACATCAAAGAACCCTGTCCCGGTCATGGTTTACATCTACGGGGGCAGTTTCAGACATGGCGATTTCGGAAGACACGTCTATGGTCCCAAATTCTTGGTAAAGCACGACGTTATTTTGGTCACGTTGAATTACAGGCTTGGGCCGTACGGTTTCATGTGTCTGGACATCCCTGAGGTGCCGGGCAATCAGGGCTTCAAAGATCAGCTCCTAGCTTTGAAATGGGTCAAGGAGCACATCCATAATTTCGGGGGCGACAGCAACAAGATCACGGTTTCTGGCGAAAGCGCTGGTGCTATCGCTGTGGACTTCCACCTAATGTATAATAAAGAGAAGCTTTTCCATAAGGCCATCATACAGAGCGGGACAACACTGTCGCCAGTCTTTTACGAGCCTTCGAGAAACGCACCAATTTTGATAGCCGAAAAACTGGGGTACATCACCGACGATTTAAACGCTGCCATTGCTTTCTTAGCCCAAGTAGACCCCAGTTTGGTCATAGCTGCCGTTTTCGATTTGGGCATCGAATTGAACGTAAGGCCATGCGTCGAAAAAAGCTTCGAAGGCGTCGAAAGATTTATTGACCAGAACTGGATCACCGCGGACGTACGTAACGCTAGGGATGTGCAAGTATTGATAGGTTTCAATGAGCACGAAAGACTCATTATACACGCGAGCGGCGATAACGATTACTTCAAAAATCTCAACGTTGTCGAGACCAAGCTATTCGACGCGTTCGACGTTGACAATGACAAGTTCAACGGAATGAAAGACATTGTACAGCACTTTTACTTCGGAGACGACGAGGTGACCATCGAATCAAAACTGGACGTGGTCAATTTCGATTCCGACATTATGTACAACCATCCTTCGTACAGAAGCATCGACAGATTCATTGAAAACAATTCGGGCGATATCTTCCTTTACCTGTTTTCTTATGTCGGAGGGAGGAATTATGTCAGGGTCAGAGATAACATTACCGTGGGAGGGGCCGTGCACGCTGACGAGTTGGGTTACCTGTTCGATATATCGTATCTGAACATCGAAACTGATGATGCTGACGTCAGAATGGTCGATGTGATGACGACCTTGTGGACTAATTTCGTTAAATACGGAAACCCTACGCCGGAAGTTACAGAACTAATACCGGTAAAATGGACTCCGATTGTTGATACTAAAACGAAACCTTTCCTAAACTTGGGCAAGGAGCTCACTGTGGGCTCCAGACCTTTTAGTGAGAGAATGGCCTTCTGGGATTTATTCTACAAGGCCAACAAGGAGCTGCAAAGGGCGTATCCCGGGGAAAACATCTGA

Protein

MSARRRVLVAVQILLYLVNESQGLARIDPLVETELGLIKGLRANDGDYAMFLGIPFGKVNASNPFGDATAYGKFDGVLEAYDDSAICPQIDEATGVYIGTIDCLHLNVYVPPSATSKNPVPVMVYIYGGSFRHGDFGRHVYGPKFLVKHDVILVTLNYRLGPYGFMCLDIPEVPGNQGFKDQLLALKWVKEHIHNFGGDSNKITVSGESAGAIAVDFHLMYNKEKLFHKAIIQSGTTLSPVFYEPSRNAPILIAEKLGYITDDLNAAIAFLAQVDPSLVIAAVFDLGIELNVRPCVEKSFEGVERFIDQNWITADVRNARDVQVLIGFNEHERLIIHASGDNDYFKNLNVVETKLFDAFDVDNDKFNGMKDIVQHFYFGDDEVTIESKLDVVNFDSDIMYNHPSYRSIDRFIENNSGDIFLYLFSYVGGRNYVRVRDNITVGGAVHADELGYLFDISYLNIETDDADVRMVDVMTTLWTNFVKYGNPTPEVTELIPVKWTPIVDTKTKPFLNLGKELTVGSRPFSERMAFWDLFYKANKELQRAYPGENI

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

B3GEF6   H9JF44   H9IUA7   A0A194RIH0   A0A3S2LSF5   B1Q141   + More
A0A2A4K075   M1RGF2   A0A194PEF7   A0A0B4RXS5   A0A1U9X1V6   A0A194Q887   A0A194PDI7   A0A2A4JZ33   A0A0N1PJ90   A0A194Q254   A0A2W1BQY3   H9J1Y0   D5G3E0   A0A194PJ15   A0A2A4JR93   A0A0N1IPF0   A0A212FJ60   A0A3G1T174   A0A1U9X1V3   A0A194Q2Q8   A0A2H1WRP2   A0A2I6RJM2   B1Q137   A0A194Q249   A0A1U9X1V1   A0A0N1IGW1   A0A2H1VAJ0   A0A0L7L0K6   A0A212FJ67   A0A0L7KY57   A0A1U9X1U7   A0A0C5BXH5   A0A0L7L1R0   A0A2H1VAI9   A0A0L7LED6   A0A2H1VCP0   A0A2H1VCN6   A0A2H1VCQ9   D5G3E2   A0A2W1BTR6   D5G3E1   A0A2A4K7E9   A0A2W1BZX4   A0A2H1VCT7   A0A2A4JU91   A0A2H1VCN0   A0A2H1VEA4   H9JDS3   A0A3S2NSH9   B1Q139   D5G3E3   B8YPE7   A0A2H1VCR3   A0A1U9X1Z0   H9IZW1   H9J066   A0A1U9X1V0   A0A212FJ53   H9IWJ7   A0A0L7L3V0   A0A2H1VCT9   A0A2A4JSH8   H9J067   A0A2W1BXP7   A0A1U9X1Z4   A0A2H1WHB4   H9IWJ8   A0A2H1VH39   A0A2A4JU71   A0A2W1BNW5   A0A2A4JYV0   A0A2W1BTK5   D5G3E4   H9IUE5   A0A2W1BVP4   A0A1U9X1X9   A0A0L7LKE5   A0A2W1BJM9   A0A2A4JHL2   A4UA26   A0A1L8D6U2   A0A2H1VCP9   A0A212EY53   A0A194QYN7   A0A194PD51   A0A1L8D6M4   A0A0L7KQ39   A0A0B4RY83   A0A0L7LMD6   A0A2A4JU07   A0A1L8D6W6   A0A1U9X1U4  

EC Number

3.1.1.-

Pubmed

19121390    26354079    28756777    20005949    22118469    26227816    + More
17257210   

EMBL

EU688968    ACD80422.1    BABH01026894    BABH01001500    KQ460205    KPJ17125.1    + More
RSAL01000258    RVE43396.1    EU523536    ACB12415.1    NWSH01000356    PCG77070.1    KC200270    AGG20205.1    KQ459606    KPI91074.1    KJ023212    AIY69040.1    KY021858    AQY62747.1    KQ459564    KPI99620.1    KPI91073.1    PCG77069.1    KQ459837    KPJ19757.1    KPI99621.1    KZ150007    PZC75160.1    BABH01007753    FJ997304    ADF43469.1    KPI91075.1    NWSH01000834    PCG73942.1    KQ460400    KPJ14974.1    AGBW02008309    OWR53771.1    MG846884    AXY94736.1    KY021841    AQY62730.1    KPI99618.1    ODYU01010533    SOQ55708.1    KY304479    AUN86410.1    EU523532    ACB12411.1    KPI99616.1    KY021842    AQY62731.1    KPJ19760.1    ODYU01001525    SOQ37859.1    JTDY01003780    KOB69017.1    OWR53772.1    JTDY01004572    KOB67996.1    KY021848    AQY62737.1    KP001158    AJN91203.2    JTDY01003509    KOB69443.1    SOQ37858.1    JTDY01001549    KOB73566.1    ODYU01001845    SOQ38610.1    SOQ38609.1    SOQ38607.1    FJ997306    ADF43471.1    KZ149903    PZC78409.1    FJ997305    ADF43470.1    NWSH01000067    PCG79999.1    PZC78410.1    SOQ38611.1    SOQ38612.1    NWSH01000660    PCG74962.1    SOQ38608.1    SOQ38604.1    BABH01003066    RVE43394.1    EU523534    ACB12413.2    FJ997307    ADF43472.1    FJ556877    ACL83460.1    SOQ38605.1    KY021887    AQY62776.1    BABH01019018    BABH01018991    BABH01018992    KY021850    AQY62739.1    OWR53773.1    BABH01021273    JTDY01003106    KOB70142.1    SOQ38606.1    PCG74961.1    BABH01018995    PZC78414.1    KY021884    AQY62773.1    ODYU01008680    SOQ52463.1    ODYU01002500    SOQ40071.1    PCG74959.1    PCG74960.1    KZ149946    PZC76749.1    NWSH01000400    PCG76673.1    PZC78412.1    FJ997308    ADF43473.1    BABH01001182    KC200271    AGG20206.1    PZC78411.1    KY021873    AQY62762.1    JTDY01000777    KOB75922.1    KZ150132    PZC73036.1    NWSH01001418    PCG71299.1    DQ680829    ABH01082.1    GEYN01000065    JAV02064.1    SOQ38613.1    AGBW02011630    OWR46387.1    KQ460947    KPJ10567.1    KPI91162.1    GEYN01000027    JAV02102.1    JTDY01007420    KOB65210.1    KJ023211    AIY69039.1    JTDY01000638    KOB76381.1    PCG74963.1    GEYN01000045    JAV02084.1    KY021838    AQY62727.1   

Proteomes

UP000005204    UP000053240    UP000283053    UP000218220    UP000053268    UP000007151    + More
UP000037510   

PRIDE

B3GEF6    H9JF44    H9IUA7    B1Q141    M1RGF2    H9J1Y0    + More
B1Q137    H9JDS3    B1Q139    H9IZW1    H9J066    H9IWJ7    H9J067    H9IWJ8    H9IUE5   

Pfam

PF00135   COesterase

Interpro

IPR002018   CarbesteraseB        + More
IPR019826   Carboxylesterase_B_AS       
IPR029058   AB_hydrolase       
IPR000997   Cholinesterase       
IPR002168   Lipase_GDXG_HIS_AS       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

B3GEF6   H9JF44   H9IUA7   A0A194RIH0   A0A3S2LSF5   B1Q141   + More
A0A2A4K075   M1RGF2   A0A194PEF7   A0A0B4RXS5   A0A1U9X1V6   A0A194Q887   A0A194PDI7   A0A2A4JZ33   A0A0N1PJ90   A0A194Q254   A0A2W1BQY3   H9J1Y0   D5G3E0   A0A194PJ15   A0A2A4JR93   A0A0N1IPF0   A0A212FJ60   A0A3G1T174   A0A1U9X1V3   A0A194Q2Q8   A0A2H1WRP2   A0A2I6RJM2   B1Q137   A0A194Q249   A0A1U9X1V1   A0A0N1IGW1   A0A2H1VAJ0   A0A0L7L0K6   A0A212FJ67   A0A0L7KY57   A0A1U9X1U7   A0A0C5BXH5   A0A0L7L1R0   A0A2H1VAI9   A0A0L7LED6   A0A2H1VCP0   A0A2H1VCN6   A0A2H1VCQ9   D5G3E2   A0A2W1BTR6   D5G3E1   A0A2A4K7E9   A0A2W1BZX4   A0A2H1VCT7   A0A2A4JU91   A0A2H1VCN0   A0A2H1VEA4   H9JDS3   A0A3S2NSH9   B1Q139   D5G3E3   B8YPE7   A0A2H1VCR3   A0A1U9X1Z0   H9IZW1   H9J066   A0A1U9X1V0   A0A212FJ53   H9IWJ7   A0A0L7L3V0   A0A2H1VCT9   A0A2A4JSH8   H9J067   A0A2W1BXP7   A0A1U9X1Z4   A0A2H1WHB4   H9IWJ8   A0A2H1VH39   A0A2A4JU71   A0A2W1BNW5   A0A2A4JYV0   A0A2W1BTK5   D5G3E4   H9IUE5   A0A2W1BVP4   A0A1U9X1X9   A0A0L7LKE5   A0A2W1BJM9   A0A2A4JHL2   A4UA26   A0A1L8D6U2   A0A2H1VCP9   A0A212EY53   A0A194QYN7   A0A194PD51   A0A1L8D6M4   A0A0L7KQ39   A0A0B4RY83   A0A0L7LMD6   A0A2A4JU07   A0A1L8D6W6   A0A1U9X1U4  

PDB

5IVK     E-value=9.78053e-45,     Score=455

KEGG

100169705    no KO assigned | (RefSeq) ae49, Bmae49, Care-13; alpha-esterase 49

GO

GO:0016787   GO:0004104   GO:0080030   GO:0016021  

SignalP

Position:   1 - 23,         Likelihood:  0.844172

 

 

Length:

550

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.498280000000001

Exp number, first 60 AAs:

0.43396

Total prob of N-in:

0.02825

outside

1  -  550

 

 

Pi

226.589498

Theta

162.131438

Tajima's D

1.300571

CLR

0.179376

CSRT

0.741462926853657

Interpretation

Uncertain