SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO14301  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA008141
Annotation
alpha-esterase_49_precursor_[Bombyx_mori]
Full name
Carboxylic ester hydrolase      
Location in the cell
Cytoplasmic   Reliability : 2.588
 

Sequence

CDS
ATGTCGGCTCGGAGACGTGTTCTTGTTGCTGTCCAAATTCTTTTATATTTGGTCAACGAAAGCCAAGGTTTGGCCAGAATTGACCCTCTGGTTGAGACCGAGCTGGGCCTGATCAAGGGTCTGAGGGCGAACGATGGGGACTACGCCATGTTCTTGGGTATACCCTTTGGAAAAGTCAACGCTAGCAATCCTTTTGGGGACGCAACGGCATATGGTAAATTTGATGGGGTATTAGAAGCTTACGATGATTCGGCGATATGCCCTCAAATTGACGAAGCCACTGGCGTCTACATTGGCACCATAGATTGTCTACATCTCAACGTATACGTTCCCCCTTCAGCGACATCAAAGAACCCTGTCCCGGTCATGGTTTACATCTACGGGGGCAGTTTCAGACATGGCGATTTCGGAAGACACGTCTATGGTCCCAAATTCTTGGTAAAGCACGACGTTATTTTGGTCACGTTGAATTACAGGCTTGGGCCGTACGGTTTCATGTGTCTGGACATCCCTGAGGTGCCGGGCAATCAGGGCTTCAAAGATCAGCTCCTAGCTTTGAAATGGGTCAAGGAGCACATCCATAATTTCGGGGGCGACAGCAACAAGATCACGGTTTCTGGCGAAAGCGCTGGTGCTATCGCTGTGGACTTCCACCTAATGTATAATAAAGAGAAGCTTTTCCATAAGGCCATCATACAGAGCGGGACAACACTGTCGCCAGTCTTTTACGAGCCTTCGAGAAACGCACCAATTTTGATAGCCGAAAAACTGGGGTACATCACCGACGATTTAAACGCTGCCATTGCTTTCTTAGCCCAAGTAGACCCCAGTTTGGTCATAGCTGCCGTTTTCGATTTGGGCATCGAATTGAACGTAAGGCCATGCGTCGAAAAAAGCTTCGAAGGCGTCGAAAGATTTATTGACCAGAACTGGATCACCGCGGACGTACGTAACGCTAGGGATGTGCAAGTATTGATAGGTTTCAATGAGCACGAAAGACTCATTATACACGCGAGCGGCGATAACGATTACTTCAAAAATCTCAACGTTGTCGAGACCAAGCTATTCGACGCGTTCGACGTTGACAATGACAAGTTCAACGGAATGAAAGACATTGTACAGCACTTTTACTTCGGAGACGACGAGGTGACCATCGAATCAAAACTGGACGTGGTCAATTTCGATTCCGACATTATGTACAACCATCCTTCGTACAGAAGCATCGACAGATTCATTGAAAACAATTCGGGCGATATCTTCCTTTACCTGTTTTCTTATGTCGGAGGGAGGAATTATGTCAGGGTCAGAGATAACATTACCGTGGGAGGGGCCGTGCACGCTGACGAGTTGGGTTACCTGTTCGATATATCGTATCTGAACATCGAAACTGATGATGCTGACGTCAGAATGGTCGATGTGATGACGACCTTGTGGACTAATTTCGTTAAATACGGAAACCCTACGCCGGAAGTTACAGAACTAATACCGGTAAAATGGACTCCGATTGTTGATACTAAAACGAAACCTTTCCTAAACTTGGGCAAGGAGCTCACTGTGGGCTCCAGACCTTTTAGTGAGAGAATGGCCTTCTGGGATTTATTCTACAAGGCCAACAAGGAGCTGCAAAGGGCGTATCCCGGGGAAAACATCTGA
Protein
MSARRRVLVAVQILLYLVNESQGLARIDPLVETELGLIKGLRANDGDYAMFLGIPFGKVNASNPFGDATAYGKFDGVLEAYDDSAICPQIDEATGVYIGTIDCLHLNVYVPPSATSKNPVPVMVYIYGGSFRHGDFGRHVYGPKFLVKHDVILVTLNYRLGPYGFMCLDIPEVPGNQGFKDQLLALKWVKEHIHNFGGDSNKITVSGESAGAIAVDFHLMYNKEKLFHKAIIQSGTTLSPVFYEPSRNAPILIAEKLGYITDDLNAAIAFLAQVDPSLVIAAVFDLGIELNVRPCVEKSFEGVERFIDQNWITADVRNARDVQVLIGFNEHERLIIHASGDNDYFKNLNVVETKLFDAFDVDNDKFNGMKDIVQHFYFGDDEVTIESKLDVVNFDSDIMYNHPSYRSIDRFIENNSGDIFLYLFSYVGGRNYVRVRDNITVGGAVHADELGYLFDISYLNIETDDADVRMVDVMTTLWTNFVKYGNPTPEVTELIPVKWTPIVDTKTKPFLNLGKELTVGSRPFSERMAFWDLFYKANKELQRAYPGENI

Summary

Similarity
Belongs to the type-B carboxylesterase/lipase family.
Feature
chain  Carboxylic ester hydrolase
EC Number
3.1.1.-
EMBL
EU688968    ACD80422.1    BABH01026894    BABH01001500    KQ460205    KPJ17125.1    + More
RSAL01000258    RVE43396.1    EU523536    ACB12415.1    NWSH01000356    PCG77070.1    KC200270    AGG20205.1    KQ459606    KPI91074.1    KJ023212    AIY69040.1    KY021858    AQY62747.1    KQ459564    KPI99620.1    KPI91073.1    PCG77069.1    KQ459837    KPJ19757.1    KPI99621.1    KZ150007    PZC75160.1    BABH01007753    FJ997304    ADF43469.1    KPI91075.1    NWSH01000834    PCG73942.1    KQ460400    KPJ14974.1    AGBW02008309    OWR53771.1    MG846884    AXY94736.1    KY021841    AQY62730.1    KPI99618.1    ODYU01010533    SOQ55708.1    KY304479    AUN86410.1    EU523532    ACB12411.1    KPI99616.1    KY021842    AQY62731.1    KPJ19760.1    ODYU01001525    SOQ37859.1    JTDY01003780    KOB69017.1    OWR53772.1    JTDY01004572    KOB67996.1    KY021848    AQY62737.1    KP001158    AJN91203.2    JTDY01003509    KOB69443.1    SOQ37858.1    JTDY01001549    KOB73566.1    ODYU01001845    SOQ38610.1    SOQ38609.1    SOQ38607.1    FJ997306    ADF43471.1    KZ149903    PZC78409.1    FJ997305    ADF43470.1    NWSH01000067    PCG79999.1    PZC78410.1    SOQ38611.1    SOQ38612.1    NWSH01000660    PCG74962.1    SOQ38608.1    SOQ38604.1    BABH01003066    RVE43394.1    EU523534    ACB12413.2    FJ997307    ADF43472.1    FJ556877    ACL83460.1    SOQ38605.1    KY021887    AQY62776.1    BABH01019018    BABH01018991    BABH01018992    KY021850    AQY62739.1    OWR53773.1    BABH01021273    JTDY01003106    KOB70142.1    SOQ38606.1    PCG74961.1    BABH01018995    PZC78414.1    KY021884    AQY62773.1    ODYU01008680    SOQ52463.1    ODYU01002500    SOQ40071.1    PCG74959.1    PCG74960.1    KZ149946    PZC76749.1    NWSH01000400    PCG76673.1    PZC78412.1    FJ997308    ADF43473.1    BABH01001182    KC200271    AGG20206.1    PZC78411.1    KY021873    AQY62762.1    JTDY01000777    KOB75922.1    KZ150132    PZC73036.1    NWSH01001418    PCG71299.1    DQ680829    ABH01082.1    GEYN01000065    JAV02064.1    SOQ38613.1    AGBW02011630    OWR46387.1    KQ460947    KPJ10567.1    KPI91162.1    GEYN01000027    JAV02102.1    JTDY01007420    KOB65210.1    KJ023211    AIY69039.1    JTDY01000638    KOB76381.1    PCG74963.1    GEYN01000045    JAV02084.1    KY021838    AQY62727.1   
Pfam
PF00135   COesterase
Interpro
IPR002018   CarbesteraseB        + More
IPR019826   Carboxylesterase_B_AS       
IPR029058   AB_hydrolase       
IPR000997   Cholinesterase       
IPR002168   Lipase_GDXG_HIS_AS       
SUPFAM
SSF53474   SSF53474       
Gene 3D
PDB
5IVK     E-value=9.78053e-45,     Score=455

Ontologies

Topology

SignalP
Position:   1 - 23,         Likelihood:  0.844172
 
 
Length:
550
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.498280000000001
Exp number, first 60 AAs:
0.43396
Total prob of N-in:
0.02825
outside
1  -  550
 
 

Population Genetic Test Statistics

Pi
226.589498
Theta
162.131438
Tajima's D
1.300571
CLR
0.179376
CSRT
0.741462926853657
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
28556443 SFEGVER 100.00 2e-06
28556443 QNFENLVHPILNK 100.00 2e-06
28556443 IDPLVETELGLIK 100.00 3e-06
28556443 YGNPTPEVTELIPVK 100.00 3e-06
28556443 AIIQSGTTLSPVFYEPSR 100.00 1e-04
28556443 AIIQSGTTLSPVFYEPSR 100.00 1e-04
28556443 YGNPTPEVTELIPVK 100.00 2e-04
28556443 NLNVVETK 100.00 2e-04
28556443 LIIHASGDNDYFK 100.00 2e-04
28556443 IDPLVETELGLIK 100.00 4e-04
28556443 LDVVNFDSDIMYNHPSYR 100.00 0.019
28556443 LFDAFDVDNDKFNGMK 100.00 0.019
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