Silkworm Genome Informatics Database

Gene

KWMTBOMO14249 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011162

Annotation

hypothetical_protein_KGM_10995_[Danaus_plexippus]

Location

Bomo_Chr23(+):21359613-21368206 View in EpiBrowser

Location in the cell

Nuclear Reliability : 4.138

CDS

ATGTGGGTGGGCGGGGCCGGCTGGTGCTGCGGCTTGCTGGCCGCCGCCGCCGTCCTGCTGCTCGTGCTGGCGCGCTGCCGGAGACGACACAACAAGCCCACGCAACAGCTCGCGGTACACGTAGTCCGCGACTCGCTGCCACCCCGCCCCCCGCAGCCCCCTCGAGTGACACATCCCTCTCTTCCCTATCCAACACCCCCACTCCCTGCGAAACGTACCCTGGCGTCGCTCGCTGGAGCTCCCGCAGACGACCCCTCGCCTCCACAGATTATTATCGTACAGAACTCCACACAAACGACAATAGCTCAATCTAGTCAGAGTCCACAACCTCCAGGCTCCCAAATCCCCGGCACGTCGAACGAACTGAGAGGTATACCGAAGTTGCCTCTGCCCGAACAGTGGATCCACAAACGGCCCGTCGATTACAAGTTTGCAAATTCGATTCCCAGGCAATTTGCTCAGATCGTTAACGCCGATCTAGGGAGTGATTTGTCCCAGGAATCCAGAGCCAAGAAATTCAGTGCAACCCGATCTCCTTCGTTGGAGAAGGACGAGAAGTCTCCGTTCGTAACGAGCGCTAAATCTCAAAAAGTTTTCGGTTTCGATCCTGATACCCTACAAAAGTTAACAGACACAGCCGATATGAGTGATGCAATGTCTCCGAAGGACACCAGTGGCAGCCAGGAAACGTCACCCAACAACTTGAGGAGATTTAAGTCGGTTAGCACCAGATTAAACATGTGTAGCGTTAACGAAGGTCTGGAGAGTCAGCAGGAGAGAGTGGAGCTTCAGAATTCTCCCCGTGTCCTCGAATGTAGTTCGGCGAAAGAGAAATCGTCTGCTCCTAAATTTGATTTCTCTCCGAGGGTTTTCGTGGATGCCATTAGTTCTCCAAGATTCTTTACGCCTCCAGAAACTGTATCTCCTATGTTCTTCGCGGAACCGTCACCGAAATCAGTATATTACGACAGTGTCAGATCACCGAAATTCTTTCCGGAGACTCCTCGTGAACCAGAAGTGCCACAGTCTCCCAGGACGCTCGGAGACCATATTAATAGGAACGGCCTAGCCGACAAGCCTAGTTCACCAAAGATTCTGAGTTCGAGGCCAAGTCCCAAAGTGCTAATGTACAATAAAGAAAACTATTTTACCTTCGATCAGTCGGGTGGGGCAGAAGAAGGATCTAGAATGTCACCCAGACCCAAGAAATATGGAGGAAGAAATTCTATAGAACGCGAAAGATTCACTCCTCCCGCTGACAAGGACGCGAGAAAGTACAGACGGCATAATAGCTGCGATACAAACTACAAAATGATTGAATTGAACGTAAAGGAAGAAAACAATGAGACCAAAGAGAAGGACGTGGTAGATTGCTGCATGAAGCTAGAATCTGTAAAGCTTGATAGTAAAATCGACGAGAAACCGAACGAATTAACGCCCAGCCCTTCGAACTCTGCGCATGCGAGAAGACAGAGGCTAAAGTCTATATCTTTAGACTCTGAAAACGCTAAGATCATAGAACAGAACCTTGGGCTTCCGATAGCGAAACAGATAAAGGATCAAATGAACGAAGCATACAAGAACCATGACATCAGCACTTCCTATGAGAGTATGGAACGCCACCAAAAAACTCCAAGCTCTGAACGTCCCGTCTTTAAGTTTGAAGATGAACAGGAGAAACAGGAACCCAAATCTCCAGTTAAGCAAAAAAAGAGCTTGAGACAGAGTTCTGATACCCAATCTTTTATTGACATGCCGAGGTTCTCGCCCAAGGAGTTCGAGATTACTGTAACCTCCGAGGAAGGAGCGACCACATCAGCTGACACCCAGATGAAACCTAAAAGCAAGAATCTAAGAAATCTAACAATCGATTTGACAAAGCGCGACACAGAACTTGAAAAGGAATTATTAGAATTCGAAAAGTTATACACTAATGCCGAAGAGAAGAAAGTGAAAACGCCCACATTAAAAGTTAAAGCCACTTCTCTGGACTCCTCGGAGACCGTCAATTTGTCTTTACCCCAGAAGAAGTCTTTGGACGTTCCCCAAAATTCGATTTCGGTACCGAATACCCCGAAGAGACAGTTGAAAAGGATACTAGCACAGAAATCGTTAAAACACGATTTTTCTGGTGGAAAATTAGGGTATAGTTCCATTCAGCCAAACGCAGACCAACGGCGTTTGCTTATGAAGGCTCAAGACAGCGGGATTTACTTGAGGGAAAACCACGCTAGTTTAATGTTATACCAGCCGAGCACATCCCGAGCCGGGTCTCGTACCATGGGCTCGTTTGACGAAAACATGTCCGACTTCGCTGAAAATGCACCAGAAATTAACATATGCGGAACCGACAATAGATTCCAACTCGACACCGGACCGAGTTTGGGCTCAAATCTGTTAAATTACAAACAGAATTTAAGCGTTTCGAGCACTAACTTGAAGACTCTTCCCGAAGGAGTTCCGTCCGACGATTTCGAACCTAGCGCGGACGACGAAAAACTTGTAAAGAAATTACACAGAAGGAATTCAAACCAAAGTTTAATGTTAAGCACTCACAGTCTCCAGGGCTCAAACTGCTCTCTCAGCAGCGCGGGCGCGTCTTGTCACAACCTGGCCACAGTGCGGACCAGCGTTTCGAACTTCAGCCTAAATTCGGATAGACAAAAGAAGTTTTCTCTAGAACGACGAGATTCTAACGTTTCTTTAATGAACACGGAACACTTGACGCCCACAACGCGGGTGATATGTTCTTCGAACACCAATTTATCCGGTGAGAGCTCGAAAAATTGTTTGCTCCAGCGCCGCGGCTCCAACAATAGCTTGACTTTAAACATTAATTCGAGTGTGCCGCTAAGTAGGCATTCTAGCAACACGTCTCTAAACAAAGAAGCTAAAGCGGGACAGAAGAAGGGTTTATTAGAGAGACGAAGCTCCAATACGTCCTTGACTTTAAACATTAATAATTCGAACCCTCAGTTGACTGTTGGGAATCGAGGATTGAGCATCTCAAATTACAACCTAAACGGTTCTAGTTGCAATTTGAGTAGGTACAATAGTAACCACAGCATCGATGCCGAACCTAGGAAGGGTATTTTAGAACGACGCAATTCCAACACCTCTCTTACCTTGAACATTCAGCCTCAAGAACCAAGAGATATTGAGATTGACGAAACCCTGCTGGAGCCGAGCCTCAAAGACCTACCGCACAGAGACAAACATCGGAAATCTTTGAGCACTGAGAACTTAATACCAAAGTCTTATAAGAATAGAACACGATTGAGATCGAACGAGAAAGGACTTGGTTTTGGATCTCACGATAATCTCTGGTCCTCTTCGTACGTGGAGTCGTCGGACTATCCTCAGAACTTGACTTACATCTGCGGGGATCAAGATAACGAAATCATATATGCCTTTGGACGTCAAGATGACCAGTTCCAACCTGGCTTTGTGAGGAATATCACAACGAAACCTTTGAGTCCTCAGAGCACTTCAGAAGACTTTAGAATGTACTTAGCGAATATGCAGCATCTTCAAAATGCGTCCAGTGTTTTGACCAGAAAACAGCTGAAAGATTTGAATGAAGTTTTCCAAAATGGCTATTCTAAAGTAAAATGCCACAACAGTTCAGAAGGTCAAAATTGCTGTTCCGGTCGAGTGGAGGAAGTCGGCCTGGAAAACCCACAAACAGTCATACCAGAGTTGGTATCGTCCCAGCCGTGCTCCGAGTATCAAAAGTCACTCCTGAGGAACTTGCACAAGGAATTTTGGGACATGCCGACGAATTTTCAGGAGAAGCCCATAGTTTCCGGGTCTCATACCAAGAACAGATACAAGACGATCCTCCCTAACGAACATTCCCGATTCATCTTGAGGAATGAGAGCGGAACTACTGAGGGTTACATCAATGCCAACTTTATAAAGGGGCATGAATACACCAAAAATACATACATAGCAACCCAGGGTCCTCTACAGAACACTATGTACGACTTCTGGTCCATGGTCTACCAGAACACCCTGGACTTCCGCAGCCGTCTCCGAGACCCTGACCCGGAACAAAACGTCCAGAAAGTAGTGATGCTCACGAATTTTATAGAGAACAACCGACAGAAATGTGAAAAATACTTTCCTTTAGAACTTAACGATGAACTTTTAGTGGACAGTGGCGAGGACAACTCTACATTTAGCGTCAAGAACTGTGGAATAGTAAAAAAATCAGGATATACAATTAGGAAATTAAGCGTAAAGTATATTCATAGTGATTGTGATAAAACACTAGACAGTGAAAGTTTAAGTGCCGTTCGCTCAGCGCAGAGCGATGTGATCGTTTACCACTATTGGTTCCACAACTGGGCGGATCATAAATGCCCTAAGGACGTTAACGCCCTGCTGAATTTAAGTCTGGACGTTCTCAAAGAGACCGCGCACAACTTCAGCTGTGAGGCCGACGGCCCTAGTGAACCCTGCAGGCGCGACAGCCCCAAGCAGAGCTCGAAATTCGTTTTTCCTCCAATAGACAACCCAGTACCCTGCGAAATGGTCGTTGATGCCTCTACCCCTTTAGACTTGAAAGGGGAGTGCCTATCGCCTCCCACTATAATACACTGTTCTGCCGGTATTGGCAGAACGGGCTGCTTAATTGCCATCTTGAATGGTATAAAACAGCTGACGACGGAGCAGAAAGTTGACGTTTTGGGCATAGTTTGTAACATGCGGTTGAACAGAGGTGGAATGGTGCAAAATTCTGAACAGTATGAGTTGATTCATAAAGTGCTGTGTCTTTACGAAAAGGCTTGTTTGCCAGATTTATAG

Protein

MWVGGAGWCCGLLAAAAVLLLVLARCRRRHNKPTQQLAVHVVRDSLPPRPPQPPRVTHPSLPYPTPPLPAKRTLASLAGAPADDPSPPQIIIVQNSTQTTIAQSSQSPQPPGSQIPGTSNELRGIPKLPLPEQWIHKRPVDYKFANSIPRQFAQIVNADLGSDLSQESRAKKFSATRSPSLEKDEKSPFVTSAKSQKVFGFDPDTLQKLTDTADMSDAMSPKDTSGSQETSPNNLRRFKSVSTRLNMCSVNEGLESQQERVELQNSPRVLECSSAKEKSSAPKFDFSPRVFVDAISSPRFFTPPETVSPMFFAEPSPKSVYYDSVRSPKFFPETPREPEVPQSPRTLGDHINRNGLADKPSSPKILSSRPSPKVLMYNKENYFTFDQSGGAEEGSRMSPRPKKYGGRNSIERERFTPPADKDARKYRRHNSCDTNYKMIELNVKEENNETKEKDVVDCCMKLESVKLDSKIDEKPNELTPSPSNSAHARRQRLKSISLDSENAKIIEQNLGLPIAKQIKDQMNEAYKNHDISTSYESMERHQKTPSSERPVFKFEDEQEKQEPKSPVKQKKSLRQSSDTQSFIDMPRFSPKEFEITVTSEEGATTSADTQMKPKSKNLRNLTIDLTKRDTELEKELLEFEKLYTNAEEKKVKTPTLKVKATSLDSSETVNLSLPQKKSLDVPQNSISVPNTPKRQLKRILAQKSLKHDFSGGKLGYSSIQPNADQRRLLMKAQDSGIYLRENHASLMLYQPSTSRAGSRTMGSFDENMSDFAENAPEINICGTDNRFQLDTGPSLGSNLLNYKQNLSVSSTNLKTLPEGVPSDDFEPSADDEKLVKKLHRRNSNQSLMLSTHSLQGSNCSLSSAGASCHNLATVRTSVSNFSLNSDRQKKFSLERRDSNVSLMNTEHLTPTTRVICSSNTNLSGESSKNCLLQRRGSNNSLTLNINSSVPLSRHSSNTSLNKEAKAGQKKGLLERRSSNTSLTLNINNSNPQLTVGNRGLSISNYNLNGSSCNLSRYNSNHSIDAEPRKGILERRNSNTSLTLNIQPQEPRDIEIDETLLEPSLKDLPHRDKHRKSLSTENLIPKSYKNRTRLRSNEKGLGFGSHDNLWSSSYVESSDYPQNLTYICGDQDNEIIYAFGRQDDQFQPGFVRNITTKPLSPQSTSEDFRMYLANMQHLQNASSVLTRKQLKDLNEVFQNGYSKVKCHNSSEGQNCCSGRVEEVGLENPQTVIPELVSSQPCSEYQKSLLRNLHKEFWDMPTNFQEKPIVSGSHTKNRYKTILPNEHSRFILRNESGTTEGYINANFIKGHEYTKNTYIATQGPLQNTMYDFWSMVYQNTLDFRSRLRDPDPEQNVQKVVMLTNFIENNRQKCEKYFPLELNDELLVDSGEDNSTFSVKNCGIVKKSGYTIRKLSVKYIHSDCDKTLDSESLSAVRSAQSDVIVYHYWFHNWADHKCPKDVNALLNLSLDVLKETAHNFSCEADGPSEPCRRDSPKQSSKFVFPPIDNPVPCEMVVDASTPLDLKGECLSPPTIIHCSAGIGRTGCLIAILNGIKQLTTEQKVDVLGIVCNMRLNRGGMVQNSEQYELIHKVLCLYEKACLPDL

Catalytic Activity

H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate

Uniprot

H9JNQ8 A0A3S2NLR1 A0A2W1BDA0 A0A2A4JIV5 A0A212F5T0 A0A194PUC2 + More
A0A194RIV7 A0A2H1VEE1 A0A1E1WBE6

Pubmed

19121390 28756777 22118469 26354079

EMBL

BABH01035233 RSAL01000287 RVE42945.1 KZ150434 PZC70880.1 NWSH01001370 + More
PCG71504.1 AGBW02010130 OWR49101.1 KQ459593 KPI96354.1 KQ460152 KPJ17374.1 ODYU01002106 SOQ39189.1 GDQN01006797 JAT84257.1

Proteomes

UP000005204 UP000283053 UP000218220 UP000007151 UP000053268 UP000053240 + More

PRIDE

H9JNQ8

Pfam

PF00102 Y_phosphatase

Interpro

IPR016130   Tyr_Pase_AS        + More
IPR029021   Prot-tyrosine_phosphatase-like
IPR003595   Tyr_Pase_cat
IPR000242   PTPase_domain
IPR000387   TYR_PHOSPHATASE_dom
IPR008356   Tyr_Pase_KIM-con

SUPFAM

SSF52799 SSF52799

Gene 3D

3.90.190.10

ProteinModelPortal

H9JNQ8 A0A3S2NLR1 A0A2W1BDA0 A0A2A4JIV5 A0A212F5T0 A0A194PUC2 + More
A0A194RIV7 A0A2H1VEE1 A0A1E1WBE6

PDB

1JLN E-value=2.31321e-43, Score=448

KEGG

101736712 K20220 tyrosine-protein phosphatase ERK [EC:3.1.3.48] | (RefSeq) uncharacterized LOC101736712

PATHWAY

04013 MAPK signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0004725 GO:0016021 GO:0006470 GO:0016311 GO:0016791 GO:0005488 GO:0005507 GO:0004713 GO:0016491 GO:0015930

PANTHER

PTHR46198

Length:

1602

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.8811

Exp number, first 60 AAs:

21.76823

Total prob of N-in:

0.99392

POSSIBLE N-term signal

sequence

inside

1 - 1

TMhelix

2 - 24

outside

25 - 1602

Pi

3.435395

Theta

4.958547

Tajima's D

1.478072

CLR

0.639225

CSRT

0.804109794510275

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics