Gene

KWMTBOMO14223

Pre Gene Modal

BGIBMGA011149

Annotation

PREDICTED:_putative_fatty_acyl-CoA_reductase_CG5065_[Bombyx_mori]

Location

Bomo_Chr23(+):20847832-20882946      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

Cytoplasmic   Reliability : 1.992 Mitochondrial   Reliability : 1.459

CDS

ATGGCGCCATCTGCTAGCGTAGCCGAATACTACGCGGGCAAATCGATTTTCATCACAGGAGCGACGGGCTTCATGGGAAAAGTATTAGTCGAGAAACTATTGAAGTCATGTCCTGGTTTGAATAAGCTCTACCTATTAATGAGGCCCAAAAAAGGGCAAAGCAGTAAAGAGAGATTAGACGACTTCCTCGGATTCAAGTTATTCGGGCCGCTACAAAAGGAAAACCCGAAGTGCTTCGAGAAACTTCACGTTGTCCCGGGCGACATACTGATGGATGACTTGGGCATATCAATAGCAGACAGAGAGCTGATACAGCGGGAGTGCCAGGTCATATTCCACTGCGCCGCCTGCGTAAGATTCGATATGTTTCTGCGTGACGCCGTCAATTTGAACACGGTAGCTACAAAGAGAGTGTTGGAGCTCGCCAAGGACTTTAATAACCTCGAGGCCTTCATCCACGTATCGACGTCCTACTGCCGCTGCGAGCTGGACCTTCTAGAAGAGAAGCTGTATCCTTCTCCACACCGTCCCGAACACATCATGGACTGCATGAGATGGATGGATGATAAGCTGGTTGCGCATATGCAGCCCAAGTTAATCGAACCCCAACCCAATACATATGCGTACACGAAGTCTCTTACGGAGGACCTAGTATCACAATACGAAGGGAGATTCCCTATTACGATCGCACGGCCATCTATCGTGACTGCAGCGTATAAGGAGCCGATACCAGGATGGGTGGACAACTTAAACGGACCAACGGGACTTCTTGTAGGAGCTGGAAAAGGGGTCATAAGAACGATGCATTGCGACGATTCGCTTCAAACTGACGTTGTGCCGGTCGATATAGCTGTCAACGCTTGCATTTTACTAGCGTATCTCACGGGCATCGAGAAACCACAAAAGATCCAAATATGCAACATAACGCAGTCAGGATTGAACCCCATCACTTGGGGCGAAGCGCTCGACATGGGTCGCGTCCACGTACGAGAGTATCCTTTCTCCGTGTGCCTCTGGTATCCCGGTGGCTCGCCAAAGAAGACGAGGATCCAGCACGAGATAGCTCTCTTCTTCACGCACCTCTTGCCGGCGTATTTCGTGGACCTATTGCTGTTTCTCTTGGGCAAGAAGACTTTCATGATCAAAGTCCAGAAACGCATCAACTACGGCCTTGAAGTCCTACAGTACTACACGACGAAGAAGTGGCTCTTTAAGAATGACAATTTCTTGGCTCTGCGCACGAAGATATCGGCTGAGGACGACAGAATATTCTATACAGACATTCAGGAGATCAACTGGAATGACTACATCAGAGAGTACATTAAGGGCGCCCGCGAATTTTGCTGCGACGAGGACCCTTCCACCTTACCGCAGGCGAGGAGACTCCAAAAACAGTAA

Protein

MAPSASVAEYYAGKSIFITGATGFMGKVLVEKLLKSCPGLNKLYLLMRPKKGQSSKERLDDFLGFKLFGPLQKENPKCFEKLHVVPGDILMDDLGISIADRELIQRECQVIFHCAACVRFDMFLRDAVNLNTVATKRVLELAKDFNNLEAFIHVSTSYCRCELDLLEEKLYPSPHRPEHIMDCMRWMDDKLVAHMQPKLIEPQPNTYAYTKSLTEDLVSQYEGRFPITIARPSIVTAAYKEPIPGWVDNLNGPTGLLVGAGKGVIRTMHCDDSLQTDVVPVDIAVNACILLAYLTGIEKPQKIQICNITQSGLNPITWGEALDMGRVHVREYPFSVCLWYPGGSPKKTRIQHEIALFFTHLLPAYFVDLLLFLLGKKTFMIKVQKRINYGLEVLQYYTTKKWLFKNDNFLALRTKISAEDDRIFYTDIQEINWNDYIREYIKGAREFCCDEDPSTLPQARRLQKQ

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Uniprot

A0A0F6Q1J2   A0A2W1BG01   A0A0F6Q309   A0A2A4JEG8   A0A2H1VMT3   A0A068FKA0   + More
A0A291P0Q5   A0A194PTU7   D9D5H7   A0A3S2TCC6   A0A212EYF9   A0A1V0M889   A0A0N0PDZ3   A0A2W1BFV3   A0A2H1V9M6   A0A2H1W4B1   D2A4K1   A0A2J7PM54   A0A1B0DP69   A0A0L0CHW4   N6TRF7   A0A067RBR1   A0A182GTG2   E9ID65   A0A3S7L465   A0A182FBM8   Q16ZP3   W5JL84   A0A151XJ37   A0A195CPE7   F4WVE2   A0A2J7PLY4   A0A0C9QJ54   A0A182R7M9   A0A1A9Z867   B4QSD5   A0A1J1INY6   Q9VCF6   A0A182KAE1   A0A195FMJ1   A0A1A9XM58   B3P8B6   A0A1B0BQB9   A0A182QRD0   A0A336L8T6   A0A182LVJ7   A0A336LBT4   A0A182W2J9   A0A336MCY8   D9MX50   A0A182NG71   A0A195EP06   A0A0K8UG05   A0A158NHJ2   A0A034WF74   A0A084W9E4   B4M0G4   A0A195AUM3   A0A088APG8   B4JT87   B4K6U4   B4PL47   B4G4B8   B3M316   A0A0A1XHC5   A0A195BV13   Q298M6   K7J200   A0A0M4EKP4   Q7QKD9   A0A1W4U818   A0A1W4ULL8   A0A232F172   A0A1B6J616   B4N9E7   A0A0C9QUP1   A0A0M9A857   A0A182VB35   A0A182XLW3   A0A1B6FF15   A0A3B0K456   A0A1W4XSR6   A0A1W4XHK8   A0A0C9RGI8   A0A0L7QMT0   A0A0F6Q4N3   W8BKK6   A0A1B6DPR8   A0A182HS11   A0A182IJC0   A0A182PEG6   A0A2W1BU73   A0A1L8DYA8   A0A0F6Q2Z9   A0A2A4JXJ6   A0A195ETK7   K7J1Z7   A0A2H8TUF0  

EC Number

1.2.1.84

Pubmed

28756777    28986331    26385554    26354079    22118469    28349297    + More
18362917    19820115    26108605    23537049    24845553    26483478    21282665    17510324    20920257    23761445    21719571    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    20542116    21347285    25348373    24438588    17550304    25830018    15632085    20075255    12364791    14747013    17210077    28648823    24495485   

EMBL

KP237921    AKD01774.1    KZ150172    PZC72604.1    KP237927    MF687599    + More
AKD01780.1    ATJ44525.1    NWSH01001668    PCG70467.1    ODYU01003164    SOQ41564.1    KJ622066    AID66654.1    MF687539    ATJ44465.1    KQ459593    KPI96398.1    GU808253    ADI82777.1    RSAL01000406    RVE41879.1    AGBW02011527    OWR46525.1    KU755488    ARD71198.1    KQ460036    KPJ18435.1    PZC72605.1    ODYU01001402    SOQ37527.1    ODYU01006217    SOQ47867.1    KQ971344    EFA05235.1    NEVH01024421    PNF17418.1    AJVK01007930    JRES01000378    KNC31840.1    APGK01054665    APGK01054666    KB741251    ENN71850.1    KK852807    KDR16085.1    JXUM01087045    JXUM01087046    KQ563607    KXJ73600.1    GL762454    EFZ21418.1    MG573169    AWJ25031.1    CH477487    EAT40115.1    ADMH02001118    ETN64063.1    KQ982080    KYQ60351.1    KQ977444    KYN02613.1    GL888387    EGI61763.1    PNF17348.1    GBYB01003579    JAG73346.1    CM000364    EDX14134.1    CVRI01000057    CRL01949.1    AE014297    AY119109    BT124991    AAF56210.1    AAM50969.1    ADI44149.1    KQ981490    KYN41164.1    CH954182    EDV53940.1    JXJN01018551    JXJN01018552    JXJN01018553    JXJN01018554    AXCN02002617    UFQS01002542    UFQT01002542    SSX14238.1    SSX33653.1    AXCM01000557    SSX14237.1    SSX33652.1    UFQS01000939    UFQT01000939    SSX07862.1    SSX28096.1    HM536634    ADI87410.1    KQ978625    KYN29624.1    GDHF01026702    JAI25612.1    ADTU01015845    ADTU01015846    ADTU01015847    ADTU01015848    ADTU01015849    GAKP01006172    GAKP01006171    JAC52780.1    ATLV01021722    KE525322    KFB46838.1    CH940650    EDW68343.1    KQ976737    KYM75938.1    CH916373    EDV94977.1    CH933806    EDW14210.1    CM000160    EDW99032.1    CH479179    EDW24466.1    CH902617    EDV42416.1    GBXI01004384    JAD09908.1    KQ976401    KYM92422.1    CM000070    EAL27929.2    CP012526    ALC47808.1    AAAB01008799    EAA03772.5    NNAY01001345    OXU24293.1    GECU01013104    JAS94602.1    CH964232    EDW80580.1    GBYB01007474    JAG77241.1    KQ435728    KOX77819.1    GECZ01020981    JAS48788.1    OUUW01000007    SPP82760.1    GBYB01007475    JAG77242.1    KQ414868    KOC59957.1    KP237930    AKD01783.1    GAMC01012744    JAB93811.1    GEDC01009624    JAS27674.1    APCN01000232    KZ149961    PZC76330.1    GFDF01002656    JAV11428.1    KP237917    AKD01770.1    NWSH01000478    PCG76112.1    KQ981975    KYN31573.1    GFXV01006098    MBW17903.1   

Proteomes

UP000218220    UP000053268    UP000283053    UP000007151    UP000053240    UP000007266    + More
UP000235965    UP000092462    UP000037069    UP000019118    UP000027135    UP000069940    UP000249989    UP000069272    UP000008820    UP000000673    UP000075809    UP000078542    UP000007755    UP000075900    UP000092445    UP000000304    UP000183832    UP000000803    UP000075881    UP000078541    UP000092443    UP000008711    UP000092460    UP000075886    UP000075883    UP000075920    UP000075884    UP000078492    UP000005205    UP000030765    UP000008792    UP000078540    UP000005203    UP000001070    UP000009192    UP000002282    UP000008744    UP000007801    UP000001819    UP000002358    UP000092553    UP000007062    UP000192221    UP000215335    UP000007798    UP000053105    UP000075903    UP000076407    UP000268350    UP000192223    UP000053825    UP000075840    UP000075880    UP000075885   

PRIDE

Q9VCF6   

Pfam

PF03015   Sterile        + More
PF07993   NAD_binding_4

Interpro

IPR026055   FAR        + More
IPR033640   FAR_C       
IPR013120   Male_sterile_NAD-bd       
IPR036291   NAD(P)-bd_dom_sf       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

A0A0F6Q1J2   A0A2W1BG01   A0A0F6Q309   A0A2A4JEG8   A0A2H1VMT3   A0A068FKA0   + More
A0A291P0Q5   A0A194PTU7   D9D5H7   A0A3S2TCC6   A0A212EYF9   A0A1V0M889   A0A0N0PDZ3   A0A2W1BFV3   A0A2H1V9M6   A0A2H1W4B1   D2A4K1   A0A2J7PM54   A0A1B0DP69   A0A0L0CHW4   N6TRF7   A0A067RBR1   A0A182GTG2   E9ID65   A0A3S7L465   A0A182FBM8   Q16ZP3   W5JL84   A0A151XJ37   A0A195CPE7   F4WVE2   A0A2J7PLY4   A0A0C9QJ54   A0A182R7M9   A0A1A9Z867   B4QSD5   A0A1J1INY6   Q9VCF6   A0A182KAE1   A0A195FMJ1   A0A1A9XM58   B3P8B6   A0A1B0BQB9   A0A182QRD0   A0A336L8T6   A0A182LVJ7   A0A336LBT4   A0A182W2J9   A0A336MCY8   D9MX50   A0A182NG71   A0A195EP06   A0A0K8UG05   A0A158NHJ2   A0A034WF74   A0A084W9E4   B4M0G4   A0A195AUM3   A0A088APG8   B4JT87   B4K6U4   B4PL47   B4G4B8   B3M316   A0A0A1XHC5   A0A195BV13   Q298M6   K7J200   A0A0M4EKP4   Q7QKD9   A0A1W4U818   A0A1W4ULL8   A0A232F172   A0A1B6J616   B4N9E7   A0A0C9QUP1   A0A0M9A857   A0A182VB35   A0A182XLW3   A0A1B6FF15   A0A3B0K456   A0A1W4XSR6   A0A1W4XHK8   A0A0C9RGI8   A0A0L7QMT0   A0A0F6Q4N3   W8BKK6   A0A1B6DPR8   A0A182HS11   A0A182IJC0   A0A182PEG6   A0A2W1BU73   A0A1L8DYA8   A0A0F6Q2Z9   A0A2A4JXJ6   A0A195ETK7   K7J1Z7   A0A2H8TUF0  

PDB

4W4T     E-value=4.83787e-06,     Score=121

KEGG

101744406    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0102965   GO:0016021   GO:0080019   GO:0006629   GO:0035336   GO:0005777   GO:0010025  

PANTHER

PTHR11011  

Length:

465

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

23.4186

Exp number, first 60 AAs:

2.4834

Total prob of N-in:

0.12812

outside

1  -  355

TMhelix

356  -  375

inside

376  -  465

 

 

Pi

16.781246

Theta

16.09732

Tajima's D

0.037391

CLR

0.758583

CSRT

0.386330683465827

Interpretation

Uncertain