Gene

KWMTBOMO14222

Pre Gene Modal

BGIBMGA011116

Annotation

PREDICTED:_putative_fatty_acyl-CoA_reductase_CG5065_[Papilio_machaon]

Location

Bomo_Chr23(-):20813213-20834891      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

Cytoplasmic   Reliability : 1.395 Nuclear   Reliability : 1.216

CDS

ATGGACGACATTACATTATTAACGACGACAGACAAAATGGAAGCTTTTCAGAAACAGATGGAATTCCTGAATGGAAACGATCCCAATATGGTGAATCGCAACCAAGAATGTCTCCCAAACTATCAACTCCTGAGTTCATGTCCAGCGGAAGCCGTGGCTGACTTCTACGACGGTTCCGTGATCCTCGTGACCGGAGGAACAGGATTTGTGGGTAAAGCCCTATTGGAGAAGCTTTTGCGGAGTTGTCCAGGTATTGAGACAGTTTATATCCTGATGAGGCCGAAGAGAGGCCTCACGGTCGAGCAGAGATACAAAGAGCTTTTGAAGAACCAAGTATTTGACCACATCAGGACTCGTTGGCCCGAGCGCTTGAGTAAGCTTCACCCCATCACGGGCGACGTTTCGGTCCAGAATCTCGGAGTTAGCGTCGACCAAAGAGAACTGCTGCGGCGTGTGACCACAGTGTTCCACTCGGCGGCCACGGTCAGGTTCACGGAGCCTCTCCACGTCGCCACCACGCTCAACGTTCAAGGCACCGCTTCGCTGCTGAAGTTGGCTGAAGACATGCCCAAGCTGAAGGCTCTAGTCCACGTCTCCACAGCGTATAGCAACGCTCCGAGGTCTTATATTGAAGAGCGCGTGTATCCCCCTCCCCATGATCCGGACAACATCGTCAGATGCACCCGGATGCTACCTCCGGAGACGGTTGAAGTTATCGCCGATAGCTTACAGGGAGATCATCCTAACCCCTACACCCTGACTAAGGCGTTGGCTGAGTCCATAGTGTATAGTCACACGGAGCTGCCGGTCTGCATTGTGAGACCTTCGATAGTGACTGCGGCTTCACAGGAGCCGTATCCGGGCTGGATCGACAATATCTACGGAGTCACCGGTGAGTAA

Protein

MDDITLLTTTDKMEAFQKQMEFLNGNDPNMVNRNQECLPNYQLLSSCPAEAVADFYDGSVILVTGGTGFVGKALLEKLLRSCPGIETVYILMRPKRGLTVEQRYKELLKNQVFDHIRTRWPERLSKLHPITGDVSVQNLGVSVDQRELLRRVTTVFHSAATVRFTEPLHVATTLNVQGTASLLKLAEDMPKLKALVHVSTAYSNAPRSYIEERVYPPPHDPDNIVRCTRMLPPETVEVIADSLQGDHPNPYTLTKALAESIVYSHTELPVCIVRPSIVTAASQEPYPGWIDNIYGVTGE

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Uniprot

H9JNL2   A0A2H1X313   A0A291P0U8   A0A289IR38   A0A2H1W4A9   A0A2A4JA51   + More
A0A437AUC7   A0A0N1IJ49   A0A212F1L0   A0A182P7M6   A0A182W4S6   A0A182RV29   A0A182MC99   A0A182S9N3   A0A182QRX8   A0A182I9E9   A0A182WYW5   A0A182USF7   Q7Q1P6   A0A182YK67   A0A084VFP2   A0A182IIY2   A0A182U4G5   A0A182NVJ4   A0A0A9Z9C6   A0A2S2P5Z2   A0A0A9ZDQ6   D2A3T2   A0A067QNH3   A0A182F9X2   Q16I40   A0A1S4FZZ5   A0A158NHP5   W5JUF8   A0A2M4CR46   A0A2J7PM60   F4WVR9   A0A151WGK7   X1WIQ8   A0A3S7L468   A0A2H8TXN6   A0A336M7Y8   A0A026W6T7   A0A224XNZ2   E2BCH8   T1I694   A0A1B0CAH9   A0A195D188   A0A195AUU5   A0A1B6CVV4   T1KB77   E9J213   E9J0F1   A0A232EYL5   A0A0L0CK11   A0A182GUG1   E0VZN1   A0A2J7PLY4   V5IE64   A0A336LRW3   A0A336MZZ9   T1PAL6   A0A067RBR1   A0A1I8M522   A0A1B6LNP5   A0A226E5U8   Q172Q7   A0A1I8PNE0   A0A023ETM2   A0A0L7RAB4   Q172Q8   B4NGD1   E0VSV6   A0A1B6J484   T1E2J9   K7J1Z7   A0A3B0JSH1   A0A1B6EM21   A0A1E1X4I5   A0A1B6G8A3   E2ALZ3   A0A131YLS0   A0A034WCC7   A0A1J1IBH8   A0A023GNB8   A0A0L0BVZ6   A0A0C9QJE0   A0A2W1BHN0   A0A2J7PM67   A0A1I8P215   A0A023F1N4   A0A1I8NID6   A0A0K8V7R7   E0VLJ7   A0A1B6CB27   B4K0W5   A0A3S7L467   N6UIA6   A0A1B6GUZ4  

EC Number

1.2.1.84

Pubmed

19121390    28986331    28756777    26354079    22118469    12364791    + More
14747013    17210077    25244985    24438588    25401762    26823975    18362917    19820115    24845553    17510324    21347285    20920257    23761445    21719571    24508170    30249741    20798317    21282665    28648823    26108605    26483478    20566863    25765539    25315136    24945155    17994087    24330624    20075255    28503490    26830274    25348373    25474469    23537049   

EMBL

BABH01035173    BABH01035174    ODYU01013061    SOQ59723.1    MF687601    ATJ44527.1    + More
MF740790    KZ150172    ASX95440.1    PZC72603.1    ODYU01006114    SOQ47672.1    NWSH01002428    PCG68320.1    RSAL01000406    RVE41880.1    KQ460036    KPJ18434.1    AGBW02010856    OWR47616.1    AXCM01005368    AXCN02002224    APCN01000946    AAAB01008980    EAA14554.4    ATLV01012451    KE524793    KFB36786.1    GBHO01021663    GBHO01003652    GBHO01003651    GBRD01007201    GDHC01010207    JAG21941.1    JAG39952.1    JAG39953.1    JAG58620.1    JAQ08422.1    GGMR01012185    MBY24804.1    GBHO01003654    GBHO01003648    GBHO01003646    GBRD01007202    GDHC01006649    JAG39950.1    JAG39956.1    JAG39958.1    JAG58619.1    JAQ11980.1    KQ971348    EFA05564.2    KK853123    KDR11037.1    CH478110    EAT33929.1    ADTU01015865    ADTU01015866    ADTU01015867    ADMH02000052    ETN67982.1    GGFL01003473    MBW67651.1    NEVH01024421    PNF17409.1    GL888393    EGI61739.1    KQ983167    KYQ46961.1    ABLF02031697    ABLF02031703    MG573172    AWJ25034.1    GFXV01007248    MBW19053.1    UFQT01000234    SSX22158.1    KK107399    QOIP01000002    EZA51341.1    RLU25399.1    GFTR01006707    JAW09719.1    GL447283    EFN86604.1    ACPB03003261    AJWK01003818    KQ976973    KYN06632.1    KQ976737    KYM75946.1    GEDC01019666    JAS17632.1    CAEY01001946    GL767714    EFZ13141.1    GL767462    EFZ13694.1    NNAY01001584    OXU23522.1    JRES01000301    KNC32585.1    JXUM01089176    KQ563750    KXJ73387.1    DS235853    EEB18837.1    PNF17348.1    GANP01010732    JAB73736.1    UFQT01000095    SSX19701.1    UFQT01004920    SSX35816.1    KA645200    AFP59829.1    KK852807    KDR16085.1    GEBQ01014616    JAT25361.1    LNIX01000006    OXA53032.1    CH477432    EAT41040.1    GAPW01000903    JAC12695.1    KQ414620    KOC67691.1    EAT41039.1    CH964251    EDW83348.1    DS235758    EEB16462.1    GECU01013738    JAS93968.1    GALA01001195    JAA93657.1    OUUW01000008    SPP83953.1    GECZ01030782    JAS38987.1    GFAC01005008    JAT94180.1    GECZ01011099    JAS58670.1    GL440703    EFN65513.1    GEDV01009049    JAP79508.1    GAKP01005761    JAC53191.1    CVRI01000047    CRK97592.1    GBBM01000775    JAC34643.1    JRES01001254    KNC24212.1    GBYB01014923    GBYB01014924    JAG84690.1    JAG84691.1    KZ150366    PZC71173.1    PNF17417.1    GBBI01003791    JAC14921.1    GDHF01017335    JAI34979.1    DS235271    EEB14253.1    GEDC01026600    JAS10698.1    CH916606    EDV90840.1    MG573165    AWJ25027.1    APGK01019136    KB740092    ENN81465.1    GECZ01003528    JAS66241.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000007151    UP000075885    + More
UP000075920    UP000075900    UP000075883    UP000075901    UP000075886    UP000075840    UP000076407    UP000075903    UP000007062    UP000076408    UP000030765    UP000075880    UP000075902    UP000075884    UP000007266    UP000027135    UP000069272    UP000008820    UP000005205    UP000000673    UP000235965    UP000007755    UP000075809    UP000007819    UP000053097    UP000279307    UP000008237    UP000015103    UP000092461    UP000078542    UP000078540    UP000015104    UP000215335    UP000037069    UP000069940    UP000249989    UP000009046    UP000095301    UP000198287    UP000095300    UP000053825    UP000007798    UP000002358    UP000268350    UP000000311    UP000183832    UP000001070    UP000019118   

PRIDE

H9JNL2    V5IE64   

Pfam

PF07993   NAD_binding_4        + More
PF03015   Sterile
PF00066   Notch
PF17102   Stealth_CR3
PF11380   Stealth_CR2
PF17101   Stealth_CR1
PF17103   Stealth_CR4

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR013120   Male_sterile_NAD-bd       
IPR033640   FAR_C       
IPR026055   FAR       
IPR031357   Stealth_CR3       
IPR000800   Notch_dom       
IPR021520   Stealth_CR2       
IPR031358   Stealth_CR1       
IPR031356   Stealth_CR4       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

H9JNL2   A0A2H1X313   A0A291P0U8   A0A289IR38   A0A2H1W4A9   A0A2A4JA51   + More
A0A437AUC7   A0A0N1IJ49   A0A212F1L0   A0A182P7M6   A0A182W4S6   A0A182RV29   A0A182MC99   A0A182S9N3   A0A182QRX8   A0A182I9E9   A0A182WYW5   A0A182USF7   Q7Q1P6   A0A182YK67   A0A084VFP2   A0A182IIY2   A0A182U4G5   A0A182NVJ4   A0A0A9Z9C6   A0A2S2P5Z2   A0A0A9ZDQ6   D2A3T2   A0A067QNH3   A0A182F9X2   Q16I40   A0A1S4FZZ5   A0A158NHP5   W5JUF8   A0A2M4CR46   A0A2J7PM60   F4WVR9   A0A151WGK7   X1WIQ8   A0A3S7L468   A0A2H8TXN6   A0A336M7Y8   A0A026W6T7   A0A224XNZ2   E2BCH8   T1I694   A0A1B0CAH9   A0A195D188   A0A195AUU5   A0A1B6CVV4   T1KB77   E9J213   E9J0F1   A0A232EYL5   A0A0L0CK11   A0A182GUG1   E0VZN1   A0A2J7PLY4   V5IE64   A0A336LRW3   A0A336MZZ9   T1PAL6   A0A067RBR1   A0A1I8M522   A0A1B6LNP5   A0A226E5U8   Q172Q7   A0A1I8PNE0   A0A023ETM2   A0A0L7RAB4   Q172Q8   B4NGD1   E0VSV6   A0A1B6J484   T1E2J9   K7J1Z7   A0A3B0JSH1   A0A1B6EM21   A0A1E1X4I5   A0A1B6G8A3   E2ALZ3   A0A131YLS0   A0A034WCC7   A0A1J1IBH8   A0A023GNB8   A0A0L0BVZ6   A0A0C9QJE0   A0A2W1BHN0   A0A2J7PM67   A0A1I8P215   A0A023F1N4   A0A1I8NID6   A0A0K8V7R7   E0VLJ7   A0A1B6CB27   B4K0W5   A0A3S7L467   N6UIA6   A0A1B6GUZ4  

PDB

4W4T     E-value=2.20227e-09,     Score=147

KEGG

101744260    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0006629   GO:0102965   GO:0080019   GO:0016021   GO:0005777   GO:0035336   GO:0010025   GO:0016772  

PANTHER

PTHR11011  

Length:

299

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0509400000000001

Exp number, first 60 AAs:

0.01707

Total prob of N-in:

0.03041

outside

1  -  299

 

 

Pi

16.289448

Theta

16.092714

Tajima's D

0.038059

CLR

1.453748

CSRT

0.387730613469327

Interpretation

Uncertain