Gene

KWMTBOMO14221

Pre Gene Modal

BGIBMGA011116

Annotation

hypothetical_protein_KGM_15059_[Danaus_plexippus]

Location

Bomo_Chr23(-):20807453-20811221      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

PlasmaMembrane   Reliability : 1.941

CDS

ATGGAGATATCCCGGGGCACGTACCGTTCCGGGTATTGCCGGGAGCGGTACGTCGTGGACTTAGTGCCGGTGGACATGGTGGTCAACTCCTGCATCCTGGCCGCTTGGAGACAAGGAGTTAAACAGCCGGGCCGCTGTCCAGTCTACAACGTGACTTCGGGGTCCATCAACCCGATCCAATGGGGCGAGTTTACCAGACTATGCGTGAAGTGGGCGAAAAAGAATCCAACGAAATACGTGATGTGGTATCCGAATTTCTCATTCACCGAATCACGGTTGATAAACACGTTTTGGGAGATTACGTGTCATTTCCTGCCGGCTTTCCTGTACGATTTGCTACTGCGAGCCCAGGGGAGGAAGGCTATCATGATGAAAATCGCCAGACGTTTCAAAATGGCCGCGGCTACAGGGGAGTACTTCGCCAACAACGAGTGGCAGTTTGGCGTGGCCGAGCTGCAGGCCTTACAGGGCGAAGCCAGTTCCACTCGAGACGCCGGTCAATTCCCCTTCTGGCCGGCGGGCTTCGATTGGGACACGTACATCGGCGCGTACATGTCCGGGATACGGAAGTTCATTCTAAAGGACACGGTCGACTCTTTACCATACGCCAGGACCAAGTTAAAAAGATTATTCTGGATACATAAATTACTGCAGGCCGCTACCGGTTATTACGTATTCAGGTTGTTAGCTGGACGTTTACGATAA

Protein

MEISRGTYRSGYCRERYVVDLVPVDMVVNSCILAAWRQGVKQPGRCPVYNVTSGSINPIQWGEFTRLCVKWAKKNPTKYVMWYPNFSFTESRLINTFWEITCHFLPAFLYDLLLRAQGRKAIMMKIARRFKMAAATGEYFANNEWQFGVAELQALQGEASSTRDAGQFPFWPAGFDWDTYIGAYMSGIRKFILKDTVDSLPYARTKLKRLFWIHKLLQAATGYYVFRLLAGRLR

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Uniprot

A0A2H1X313   I4DNF8   A0A194PUH2   A0A2A4JA51   A0A212F1L0   A0A289IR38   + More
A0A291P0U8   A0A437AUC7   H9JNL2   A0A0N1IJ49   A0A0N1INU5   B0X6W9   A0A2P8XFM8   A0A224XNZ2   A0A2R7W2J3   T1I694   A0A1B0D6L7   A0A067QNH3   A0A1B0CAH9   A0A1S4FZZ5   Q16I40   A0A084VFP2   A0A2J7PM60   E9J0F1   A0A2S2R0W4   A0A182LM94   A0A0A9ZDQ6   A0A182YK67   A0A182U4G5   A0A182WYW5   A0A182F9X2   A0A182USF7   A0A182MC99   A0A182I9E9   A0A182NVJ4   A0A182S9N3   A0A3S7L468   A0A026W6T7   A0A182QRX8   A0A195D188   A0A1S3D306   A0A151WGK7   E2BCH8   A0A182W4S6   A0A2H8TXN6   A0A195AUU5   A0A2M4CR46   Q7Q1P6   A0A182RV29   X1WIQ8   A0A182IIY2   A0A182P7M6   A0A336M7Y8   A0A195EUK6   E2ALZ3   W5JUF8   U4USD2   Q5PT81   Q5PT70   Q5PT95   Q5PT72   Q5PT67   D2A3T2   Q5PT93   Q5PT85   Q5PT69   K7J4Y9   A0A232EYL5   A0A158NHP5   A0A336MJD1   E0VZN1   A0A1B6D513   E9J213   A0A0T6AZY6   A0A2J7PLY4   D2A660   A0A067R949   A0A2J7PM67   K7J1Z7   A0A158NHJ4   A0A195D193   A0A195AV89   A0A151WGN3   G3KIJ9   A0A194PSL9   A0A437BVI2   A0A2H1W002   A0A0N1IPU7   A0A1W4WEK2   E0VLJ7   A0A1B0G7W2  

EC Number

1.2.1.84

Pubmed

22651552    26354079    22118469    28756777    28986331    19121390    + More
29403074    24845553    17510324    24438588    21282665    20966253    25401762    26823975    25244985    24508170    30249741    20798317    12364791    14747013    17210077    20920257    23761445    23537049    16076241    18362917    19820115    20075255    28648823    21347285    20566863    21918929   

EMBL

ODYU01013061    SOQ59723.1    AK402885    BAM19448.1    KQ459593    KPI96399.1    + More
NWSH01002428    PCG68320.1    AGBW02010856    OWR47616.1    MF740790    KZ150172    ASX95440.1    PZC72603.1    MF687601    ATJ44527.1    RSAL01000406    RVE41880.1    BABH01035173    BABH01035174    KQ460036    KPJ18434.1    KQ460970    KPJ10162.1    DS232427    EDS41640.1    PYGN01002310    PSN30813.1    GFTR01006707    JAW09719.1    KK854229    PTY13401.1    ACPB03003261    AJVK01012079    AJVK01012080    AJVK01012081    KK853123    KDR11037.1    AJWK01003818    CH478110    EAT33929.1    ATLV01012451    KE524793    KFB36786.1    NEVH01024421    PNF17409.1    GL767462    EFZ13694.1    GGMS01014436    MBY83639.1    GBHO01003654    GBHO01003648    GBHO01003646    GBRD01007202    GDHC01006649    JAG39950.1    JAG39956.1    JAG39958.1    JAG58619.1    JAQ11980.1    AXCM01005368    APCN01000946    MG573172    AWJ25034.1    KK107399    QOIP01000002    EZA51341.1    RLU25399.1    AXCN02002224    KQ976973    KYN06632.1    KQ983167    KYQ46961.1    GL447283    EFN86604.1    GFXV01007248    MBW19053.1    KQ976737    KYM75946.1    GGFL01003473    MBW67651.1    AAAB01008980    EAA14554.4    ABLF02031697    ABLF02031703    UFQT01000234    SSX22158.1    KQ981975    KYN31582.1    GL440703    EFN65513.1    ADMH02000052    ETN67982.1    KB632429    ERL95428.1    AY825897    AY825898    AAV70461.1    AY825909    AAV70472.1    AY825883    AY825884    AY825891    AY825892    AAV70447.1    AAV70454.1    AY825907    AY825908    AAV70470.1    AY825879    AY825880    AY825881    AY825882    AY825887    AY825888    AY825889    AY825890    AY825895    AY825896    AY825901    AY825902    AY825903    AY825904    AY825905    AY825906    AY825911    AY825912    AY825913    AY825914    AY825915    AY825916    AY825919    AY825920    AY825921    AY825922    AAV70442.1    AAV70444.1    AAV70450.1    AAV70452.1    AAV70458.1    AAV70464.1    AAV70466.1    AAV70468.1    AAV70475.1    AAV70476.1    AAV70478.1    AAV70482.1    AAV70484.1    KQ971348    EFA05564.2    AY825885    AY825886    AAV70449.1    AY825893    AY825894    AAV70457.1    AY825910    AAV70473.1    NNAY01001584    OXU23522.1    ADTU01015865    ADTU01015866    ADTU01015867    UFQS01001009    UFQT01001009    SSX08551.1    SSX28467.1    DS235853    EEB18837.1    GEDC01016507    JAS20791.1    GL767714    EFZ13141.1    LJIG01022455    KRT80507.1    PNF17348.1    KQ971346    EFA04974.1    KK852807    KDR16086.1    PNF17417.1    ADTU01015858    KYN06637.1    KYM75940.1    KYQ46967.1    JN243756    AEO89346.1    KPI96431.1    RSAL01000005    RVE54396.1    ODYU01005509    SOQ46429.1    KPJ18402.1    DS235271    EEB14253.1    CCAG010021504   

Proteomes

UP000053268    UP000218220    UP000007151    UP000283053    UP000005204    UP000053240    + More
UP000002320    UP000245037    UP000015103    UP000092462    UP000027135    UP000092461    UP000008820    UP000030765    UP000235965    UP000075882    UP000076408    UP000075902    UP000076407    UP000069272    UP000075903    UP000075883    UP000075840    UP000075884    UP000075901    UP000053097    UP000279307    UP000075886    UP000078542    UP000079169    UP000075809    UP000008237    UP000075920    UP000078540    UP000007062    UP000075900    UP000007819    UP000075880    UP000075885    UP000078541    UP000000311    UP000000673    UP000030742    UP000007266    UP000002358    UP000215335    UP000005205    UP000009046    UP000192223    UP000092444   

PRIDE

H9JNL2   

Pfam

PF03015   Sterile        + More
PF07993   NAD_binding_4
PF00066   Notch
PF17102   Stealth_CR3
PF11380   Stealth_CR2
PF17101   Stealth_CR1
PF17103   Stealth_CR4

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR013120   Male_sterile_NAD-bd       
IPR033640   FAR_C       
IPR026055   FAR       
IPR031357   Stealth_CR3       
IPR000800   Notch_dom       
IPR021520   Stealth_CR2       
IPR031358   Stealth_CR1       
IPR031356   Stealth_CR4       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

A0A2H1X313   I4DNF8   A0A194PUH2   A0A2A4JA51   A0A212F1L0   A0A289IR38   + More
A0A291P0U8   A0A437AUC7   H9JNL2   A0A0N1IJ49   A0A0N1INU5   B0X6W9   A0A2P8XFM8   A0A224XNZ2   A0A2R7W2J3   T1I694   A0A1B0D6L7   A0A067QNH3   A0A1B0CAH9   A0A1S4FZZ5   Q16I40   A0A084VFP2   A0A2J7PM60   E9J0F1   A0A2S2R0W4   A0A182LM94   A0A0A9ZDQ6   A0A182YK67   A0A182U4G5   A0A182WYW5   A0A182F9X2   A0A182USF7   A0A182MC99   A0A182I9E9   A0A182NVJ4   A0A182S9N3   A0A3S7L468   A0A026W6T7   A0A182QRX8   A0A195D188   A0A1S3D306   A0A151WGK7   E2BCH8   A0A182W4S6   A0A2H8TXN6   A0A195AUU5   A0A2M4CR46   Q7Q1P6   A0A182RV29   X1WIQ8   A0A182IIY2   A0A182P7M6   A0A336M7Y8   A0A195EUK6   E2ALZ3   W5JUF8   U4USD2   Q5PT81   Q5PT70   Q5PT95   Q5PT72   Q5PT67   D2A3T2   Q5PT93   Q5PT85   Q5PT69   K7J4Y9   A0A232EYL5   A0A158NHP5   A0A336MJD1   E0VZN1   A0A1B6D513   E9J213   A0A0T6AZY6   A0A2J7PLY4   D2A660   A0A067R949   A0A2J7PM67   K7J1Z7   A0A158NHJ4   A0A195D193   A0A195AV89   A0A151WGN3   G3KIJ9   A0A194PSL9   A0A437BVI2   A0A2H1W002   A0A0N1IPU7   A0A1W4WEK2   E0VLJ7   A0A1B0G7W2  

KEGG

101744260    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

GO

GO:0102965   GO:0080019   GO:0006629   GO:0016021   GO:0016772   GO:0005777   GO:0035336   GO:0010025  

PANTHER

PTHR11011  

Length:

234

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

10.58355

Exp number, first 60 AAs:

0.83848

Total prob of N-in:

0.30543

outside

1  -  234

 

 

Pi

5.687692

Theta

7.171621

Tajima's D

-0.897251

CLR

0.850642

CSRT

0.15729213539323

Interpretation

Uncertain