Gene

KWMTBOMO14203

Pre Gene Modal

BGIBMGA011140

Annotation

PREDICTED:_fatty_acyl-CoA_reductase_1-like_[Bombyx_mori]

Location

Bomo_Chr23(-):20397192-20408532      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

Cytoplasmic   Reliability : 1.432 Mitochondrial   Reliability : 1.705

CDS

ATGGACAGCGCTTTGGCTTTGGAGATCGAGCAGGTCTCGCGTCAGAAGGCGCTGGAGGAGGAAGCGCTTCGCGGCGAGTCGGCTGTGCGGCAGTTCTACGCGGGAACCACAGCGCTGATCACTGGAGGGACGGGCTTCATCGGGAAACAACTCATAGAGAAGCTTCTAAGGTCGTGCGACGTTAAACGAATTTACCTGTTGATTAGGTCGAAGAAAGGGAAATCGATGCAAGAGAGACTAAAGTCACAATTAAATGATCCAGTATACGACAATTTACGGTCTCAACAACCAGATTTCACTCGGAAAGTTATACCGGTGGAAGGCGACATCTCAGAACTAGGCGTCGGCCTGAACAACGAAGACAGGATGAAGCTTGCGCAAGAGGTGAATGTGATATTCCATGTGGCTGCCACGACCAGGTTCGAAGAGCCACTGAAGAAGGCCACATTCATCAACGTCAGAGGAACCAGGGAGATCATGGAATTGGCCAAATGCTGCAAAGATCTAAGGTCCTTCGTACACGTGTCAACTGCGTTCTCTAATGCAACCAAGAGCAGAATAAATCACGATTTGGAAGAGAAAATCTATGAAAGCCCTGTCCCTCCGGAAGTCATGATACATCTCGCGGAGACAGTCGAAGAATGCAGACTCAACGCGATCACTGCTGATTTGATAAGGGACTGGCCCAACACGTACTGTTTCACGAAGGCCATAGCCGAGGATGTCGTGCGTACAATGGGCAAGGATTTACCTGTGGCCATAGTGAGGCCACCCGTAGTTATCTGCACGCTCAATGAACCCACTCCTGGATGGGTGGATATGAGCTCGGTGATCGGTCCTAGTGGGGTAAGTGCAAATCAAAGTTGGGACTTGTTAATAGCGGTTCGCACAGTGTACATAGTTGGGGTTTATTTTAAGATTTTTAAGCACACCCATGGTAACACCTTACTGCCCAATTCTCAAGCGAAGTAA

Protein

MDSALALEIEQVSRQKALEEEALRGESAVRQFYAGTTALITGGTGFIGKQLIEKLLRSCDVKRIYLLIRSKKGKSMQERLKSQLNDPVYDNLRSQQPDFTRKVIPVEGDISELGVGLNNEDRMKLAQEVNVIFHVAATTRFEEPLKKATFINVRGTREIMELAKCCKDLRSFVHVSTAFSNATKSRINHDLEEKIYESPVPPEVMIHLAETVEECRLNAITADLIRDWPNTYCFTKAIAEDVVRTMGKDLPVAIVRPPVVICTLNEPTPGWVDMSSVIGPSGVSANQSWDLLIAVRTVYIVGVYFKIFKHTHGNTLLPNSQAK

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Uniprot

H9JNN6   H9JNM2   H9JWY2   H9JNN4   A0A2A4K1U6   A0A2A4JYT4   + More
A0A2A4K1F7   A0A2A4JY42   A0A2H1VWV0   A0A2W1B8Q0   A0A2A4K2D3   A0A2W1BH40   A0A2H1VAJ7   A0A2A4JY41   A0A2A4J5Y0   A0A2W1BUR6   A0A2W1BRZ8   A0A0P0ELA9   A0A2A4JIF6   A0A2W1BEZ6   A0A291P0Q6   A0A212ER01   A0A2W1BFX3   A0A2H1WT26   A0A194R4R4   A0A194PZ57   A0A194PSN1   A0A0N1PK47   A0A2A4JG81   A0A194PT03   A0A2H1VVN7   U5KFQ5   A0A194PV95   A0A0P0EM43   A0A1V0M874   A0A0F6Q1J7   A0A2W1BH51   A0A0F6Q2N3   A0A194PTV2   A0A194QZH1   A0A068FK94   A0A2A4JS90   A0A2H1VVB2   H9JNP1   A0A0N1I9W9   A0A2J7RN95   A0A212F0D5   A0A067R2Y2   U4UBB5   N6TBL5   A0A2J7RNB9   A0A195BRC5   A0A158P2S4   K7J6N4   A0A3L8DXX4   A0A232EYC4   A0A195DFI7   A0A151X2I2   A0A193CHN6   A0A1J1J054   K7J6N1   F4W5T8   A0A195C2N5   A0A232F2D0   A0A1Y1LHX9   A0A336L0D6   A0A1B0GID8   A0A195EZP6   E2AWD8   A0A1B6DYP0   E9I8G2   A0A310S4M5   E2BCH8   A0A069DU52   E2AKQ3   A0A0L0BW16   A0A0M9ABB1   A0A3Q8FLY7   A0A0A9WBX3   A0A2D0T2W8   A0A0C9PMV0   A0A1B0CRM9   A0A2D0T371   T1HHV9   A0A1I8P794   A0A2J7QR94   A0A1B6EEG7   W5U6W2   A0A0L7RAS9   A0A0A9XGI9   A0A158NHD8   D2A5T7   A0A146LDG8   E2AWD9   K7J7I4  

EC Number

1.2.1.84

Pubmed

19121390    28756777    26445454    28986331    22118469    26354079    + More
24053512    28349297    26385554    24845553    23537049    21347285    20075255    30249741    28648823    27271970    21719571    28004739    20798317    21282665    26334808    26108605    25401762    26823975    23127152    18362917    19820115   

EMBL

BABH01035122    BABH01035123    BABH01035124    BABH01035129    BABH01035130    BABH01035131    + More
BABH01035132    BABH01042202    BABH01042203    BABH01042204    BABH01035110    NWSH01000263    PCG77898.1    NWSH01000368    PCG76936.1    PCG77899.1    PCG76935.1    ODYU01004617    SOQ44684.1    KZ150217    PZC72129.1    NWSH01000230    PCG78176.1    PZC72126.1    ODYU01001262    SOQ37234.1    PCG76937.1    NWSH01003107    PCG66934.1    KZ149959    PZC76396.1    PZC76395.1    KT261699    ALJ30239.1    NWSH01001446    PCG71213.1    KZ150147    PZC72871.1    MF687542    ATJ44468.1    AGBW02013183    OWR43905.1    PZC72127.1    ODYU01010853    SOQ56210.1    KQ460890    KPJ10851.1    KQ459593    KPI96440.1    KPI96441.1    KQ460036    KPJ18429.1    NWSH01001490    PCG71095.1    KPI96442.1    ODYU01004416    SOQ44264.1    JX989158    AGR49317.1    KPI96679.1    KT261695    ALJ30235.1    KU755476    ARD71186.1    KP237926    MF687596    AKD01779.1    ATJ44522.1    PZC72130.1    KP237913    MF687534    AKD01766.1    ATJ44460.1    KPI96403.1    KPJ10852.1    KJ622061    AID66649.1    NWSH01000716    PCG74636.1    ODYU01004649    SOQ44753.1    BABH01035163    BABH01035164    KPJ18430.1    NEVH01002545    PNF42310.1    AGBW02011118    OWR47192.1    KK852740    KDR17399.1    KB632003    ERL87876.1    APGK01044237    APGK01044238    KB741021    ENN75098.1    PNF42309.1    KQ976417    KYM89582.1    ADTU01007436    ADTU01007437    QOIP01000002    RLU25314.1    NNAY01001641    OXU23345.1    KQ980903    KYN11612.1    KQ982576    KYQ54647.1    KU963289    ANN23959.1    CVRI01000065    CRL05837.1    GL887695    EGI70414.1    KQ978379    KYM94471.1    NNAY01001243    OXU24628.1    GEZM01061226    JAV70627.1    UFQS01001285    UFQT01001285    SSX10116.1    SSX29838.1    AJWK01013757    KQ981905    KYN33349.1    GL443286    EFN62238.1    GEDC01006523    JAS30775.1    GL761538    EFZ23139.1    KQ776822    OAD52165.1    GL447283    EFN86604.1    GBGD01001246    JAC87643.1    GL440368    EFN65993.1    JRES01001250    KNC24227.1    KQ435694    KOX80980.1    MG573160    AWJ25022.1    GBHO01038325    GBHO01038321    GBRD01012464    GDHC01011251    JAG05279.1    JAG05283.1    JAG53360.1    JAQ07378.1    GBYB01002483    JAG72250.1    AJWK01024997    AJWK01024998    AJWK01024999    ACPB03001017    NEVH01011924    PNF31087.1    GEDC01000976    JAS36322.1    JT406763    AHH37716.1    KQ414617    KOC68027.1    GBHO01025676    JAG17928.1    ADTU01015701    ADTU01015702    KQ971345    EFA05024.1    GDHC01012276    JAQ06353.1    EFN62239.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000053268    UP000235965    + More
UP000027135    UP000030742    UP000019118    UP000078540    UP000005205    UP000002358    UP000279307    UP000215335    UP000078492    UP000075809    UP000183832    UP000007755    UP000078542    UP000092461    UP000078541    UP000000311    UP000008237    UP000037069    UP000053105    UP000221080    UP000015103    UP000095300    UP000053825    UP000007266   

PRIDE

H9JNN6    H9JNM2    H9JWY2    H9JNN4    H9JNP1   

Pfam

PF07993   NAD_binding_4        + More
PF03015   Sterile

Interpro

IPR026055   FAR        + More
IPR013120   Male_sterile_NAD-bd       
IPR036291   NAD(P)-bd_dom_sf       
IPR033640   FAR_C       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

H9JNN6   H9JNM2   H9JWY2   H9JNN4   A0A2A4K1U6   A0A2A4JYT4   + More
A0A2A4K1F7   A0A2A4JY42   A0A2H1VWV0   A0A2W1B8Q0   A0A2A4K2D3   A0A2W1BH40   A0A2H1VAJ7   A0A2A4JY41   A0A2A4J5Y0   A0A2W1BUR6   A0A2W1BRZ8   A0A0P0ELA9   A0A2A4JIF6   A0A2W1BEZ6   A0A291P0Q6   A0A212ER01   A0A2W1BFX3   A0A2H1WT26   A0A194R4R4   A0A194PZ57   A0A194PSN1   A0A0N1PK47   A0A2A4JG81   A0A194PT03   A0A2H1VVN7   U5KFQ5   A0A194PV95   A0A0P0EM43   A0A1V0M874   A0A0F6Q1J7   A0A2W1BH51   A0A0F6Q2N3   A0A194PTV2   A0A194QZH1   A0A068FK94   A0A2A4JS90   A0A2H1VVB2   H9JNP1   A0A0N1I9W9   A0A2J7RN95   A0A212F0D5   A0A067R2Y2   U4UBB5   N6TBL5   A0A2J7RNB9   A0A195BRC5   A0A158P2S4   K7J6N4   A0A3L8DXX4   A0A232EYC4   A0A195DFI7   A0A151X2I2   A0A193CHN6   A0A1J1J054   K7J6N1   F4W5T8   A0A195C2N5   A0A232F2D0   A0A1Y1LHX9   A0A336L0D6   A0A1B0GID8   A0A195EZP6   E2AWD8   A0A1B6DYP0   E9I8G2   A0A310S4M5   E2BCH8   A0A069DU52   E2AKQ3   A0A0L0BW16   A0A0M9ABB1   A0A3Q8FLY7   A0A0A9WBX3   A0A2D0T2W8   A0A0C9PMV0   A0A1B0CRM9   A0A2D0T371   T1HHV9   A0A1I8P794   A0A2J7QR94   A0A1B6EEG7   W5U6W2   A0A0L7RAS9   A0A0A9XGI9   A0A158NHD8   D2A5T7   A0A146LDG8   E2AWD9   K7J7I4  

PDB

4W4T     E-value=8.37677e-11,     Score=160

KEGG

105841245    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0006629   GO:0102965   GO:0080019   GO:0016021   GO:0035336   GO:0005777   GO:0010025  

PANTHER

PTHR11011  

Length:

323

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.51029

Exp number, first 60 AAs:

0.14347

Total prob of N-in:

0.01033

outside

1  -  323

 

 

Pi

19.340922

Theta

22.526961

Tajima's D

-0.503088

CLR

0.272552

CSRT

0.24058797060147

Interpretation

Uncertain