Gene

KWMTBOMO14200

Pre Gene Modal

BGIBMGA011140

Annotation

PREDICTED:_fatty_acyl-CoA_reductase_1-like_[Bombyx_mori]

Location

Bomo_Chr23(+):20334942-20340779      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

Cytoplasmic   Reliability : 2.554

CDS

ATGGACAGCGCTCTGGCTTTGGAGATCGAGCAGGTCTCGCGTCAGAAGGCGCTGGAGGAGGAAGCGCTTCGCGGCGAGTCGGCTGTGCGGCAGTTCTACGCGGGAACCACAGCGCTGATCACTGGAGGGACGGGCTTCATCGGGAAACAACTCATAGAGAAGCTTCTAAGATCGTGCGACGTTAAGCGGCTTTACATATTGGCACGATCGAAAAAGGGACTGTCTATGGAAGAAAGGCTCCAGTTACAATTTAAAGATCCTGTATACGACAATTTACGGTCTCAACAACCAGATTTCGCTCGGAAAGTGATACCTGTCGAAGGTGACATCTCAGAACTAGGCGTCGGCTTGAACGACGAAGACAGGATGAAGCTTGAGCAAGAGGCGAATGTCATATTCCACGTGGCCGCCACGACCAGGTTCGAAGAGCCACTAAAGAAGGCCACATTCATCAACGTCAGAGGAACCAGGGAGATCCTTGAATTGGCCAAATGCTGCAAAAATCTAAGATGCTTCGTACACGTGTCAACTGCGTTCTTCAATGCCACGAAGACCAAAATAAATCACACCATTGAGGAGAAATTCTATGAAAGCCCTATCCCTCCGGAAGTCATGATACAGCTCGCGGAGACAGTCGAAGAATGCAGACTCAACGCGATCACTGCTGATTTGATAAGGGACTGGCCCAACACGTACTGCTTCACGAAGGCCATAGCGGAGGATGTCGTGCGTACAATGGGCAAGGCTTTACCTGTGGCCATAGTGAGGCCACCCGCAGGCAAGTATTCAAGGGCTCTTCTTTCCGAAATAGTATAG

Protein

MDSALALEIEQVSRQKALEEEALRGESAVRQFYAGTTALITGGTGFIGKQLIEKLLRSCDVKRLYILARSKKGLSMEERLQLQFKDPVYDNLRSQQPDFARKVIPVEGDISELGVGLNDEDRMKLEQEANVIFHVAATTRFEEPLKKATFINVRGTREILELAKCCKNLRCFVHVSTAFFNATKTKINHTIEEKFYESPIPPEVMIQLAETVEECRLNAITADLIRDWPNTYCFTKAIAEDVVRTMGKALPVAIVRPPAGKYSRALLSEIV

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Uniprot

H9JNN6   H9JNN4   H9JNM2   H9JWY2   A0A2A4JYT4   A0A2W1B8Q0   + More
A0A2A4JY42   A0A2A4K1U6   A0A2A4K1F7   A0A2H1VAJ7   A0A2H1VWV0   A0A0P0ELA9   A0A2W1BFX3   A0A2A4K2D3   A0A2A4J5Y0   A0A2A4JG81   A0A2W1BH40   A0A2A4JIF6   A0A2W1BUR6   A0A2A4JY41   A0A2W1BRZ8   A0A2H1WT26   A0A2W1BEZ6   A0A291P0Q6   A0A194PSN1   A0A194R4R4   A0A212ER01   A0A194PZ57   A0A194QZH1   A0A0N1PK47   U5KFQ5   A0A194PV95   A0A0P0EM43   A0A2W1BAL1   A0A1V0M874   A0A2W1BC59   A0A2W1BH51   A0A0F6Q1J7   A0A194PTV2   A0A0F6Q2N3   A0A068FK94   A0A2A4JS90   A0A2H1VVN7   A0A194PT03   A0A2H1VVB2   A0A212F0D5   A0A0N1I9W9   H9JNP1   B6SDB1   N6TBL5   U4UBB5   A0A0N0PFV2   A0A067R2Y2   A0A0F6NS76   A0A2J7RN95   A0A1Y1LHX9   A0A336L0D6   A0A1J1J054   K7J6N4   A0A151XFK4   A0A2J7RNB9   A0A0J7L758   A0A232EYC4   A0A1B0GID8   A0A3L8DXX4   E2AWD8   A0A195EE25   A0A158NHD8   K7J6N1   D2A5E7   A0A195BRC5   A0A1Y1K3T9   A0A158P2S4   A0A1B0CRM9   A0A2J7QR94   A0A232F2D0   K7J7I4   F4WU72   A0A0A9XGI9   A0A146LDG8   A0A068FRD3   A0A0A9WBX3   A0A0C9PMV0   F4W5T8   E2BCH8   E2AWD9   A0A195DFI7   K7J7I5   A0A0L0BW16   A0A1B6DYP0   A0A1B6DLK7   A0A151X2I2   A0A1B6CR01   A0A195C2N5   A0A195EZP6   A0A232EN92   A0A336LP21   E2AKQ3   A0A1I8P794  

EC Number

1.2.1.84

Pubmed

19121390    28756777    26445454    28986331    26354079    22118469    + More
24053512    28349297    26385554    19041942    23537049    24845553    28004739    20075255    28648823    30249741    20798317    21347285    18362917    19820115    21719571    25401762    26823975    26108605   

EMBL

BABH01035122    BABH01035123    BABH01035124    BABH01035110    BABH01035129    BABH01035130    + More
BABH01035131    BABH01035132    BABH01042202    BABH01042203    BABH01042204    NWSH01000368    PCG76936.1    KZ150217    PZC72129.1    PCG76935.1    NWSH01000263    PCG77898.1    PCG77899.1    ODYU01001262    SOQ37234.1    ODYU01004617    SOQ44684.1    KT261699    ALJ30239.1    PZC72127.1    NWSH01000230    PCG78176.1    NWSH01003107    PCG66934.1    NWSH01001490    PCG71095.1    PZC72126.1    NWSH01001446    PCG71213.1    KZ149959    PZC76396.1    PCG76937.1    PZC76395.1    ODYU01010853    SOQ56210.1    KZ150147    PZC72871.1    MF687542    ATJ44468.1    KQ459593    KPI96441.1    KQ460890    KPJ10851.1    AGBW02013183    OWR43905.1    KPI96440.1    KPJ10852.1    KQ460036    KPJ18429.1    JX989158    AGR49317.1    KPI96679.1    KT261695    ALJ30235.1    PZC72128.1    KU755476    ARD71186.1    PZC72879.1    PZC72130.1    KP237926    MF687596    AKD01779.1    ATJ44522.1    KPI96403.1    KP237913    MF687534    AKD01766.1    ATJ44460.1    KJ622061    AID66649.1    NWSH01000716    PCG74636.1    ODYU01004416    SOQ44264.1    KPI96442.1    ODYU01004649    SOQ44753.1    AGBW02011118    OWR47192.1    KPJ18430.1    BABH01035163    BABH01035164    EU817393    ACJ06508.1    APGK01044237    APGK01044238    KB741021    ENN75098.1    KB632003    ERL87876.1    LADJ01066115    KPJ21681.1    KK852740    KDR17399.1    KF805978    AIS85929.1    NEVH01002545    PNF42310.1    GEZM01061226    JAV70627.1    UFQS01001285    UFQT01001285    SSX10116.1    SSX29838.1    CVRI01000065    CRL05837.1    KQ982194    KYQ59115.1    PNF42309.1    LBMM01000418    KMQ98413.1    NNAY01001641    OXU23345.1    AJWK01013757    QOIP01000002    RLU25314.1    GL443286    EFN62238.1    KQ979039    KYN23453.1    ADTU01015701    ADTU01015702    KQ971345    EFA05090.1    KQ976417    KYM89582.1    GEZM01093770    JAV56139.1    ADTU01007436    ADTU01007437    AJWK01024997    AJWK01024998    AJWK01024999    NEVH01011924    PNF31087.1    NNAY01001243    OXU24628.1    GL888353    EGI62240.1    GBHO01025676    JAG17928.1    GDHC01012276    JAQ06353.1    KJ622062    AID66650.1    GBHO01038325    GBHO01038321    GBRD01012464    GDHC01011251    JAG05279.1    JAG05283.1    JAG53360.1    JAQ07378.1    GBYB01002483    JAG72250.1    GL887695    EGI70414.1    GL447283    EFN86604.1    EFN62239.1    KQ980903    KYN11612.1    JRES01001250    KNC24227.1    GEDC01006523    JAS30775.1    GEDC01010770    JAS26528.1    KQ982576    KYQ54647.1    GEDC01021312    JAS15986.1    KQ978379    KYM94471.1    KQ981905    KYN33349.1    NNAY01003198    OXU19820.1    UFQS01000040    UFQT01000040    SSW98155.1    SSX18541.1    GL440368    EFN65993.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000019118    + More
UP000030742    UP000027135    UP000235965    UP000183832    UP000002358    UP000075809    UP000036403    UP000215335    UP000092461    UP000279307    UP000000311    UP000078492    UP000005205    UP000007266    UP000078540    UP000007755    UP000008237    UP000037069    UP000078542    UP000078541    UP000095300   

PRIDE

H9JNN6    H9JNN4    H9JNM2    H9JWY2    H9JNP1   

Pfam

PF07993   NAD_binding_4        + More
PF03015   Sterile

Interpro

IPR026055   FAR        + More
IPR013120   Male_sterile_NAD-bd       
IPR036291   NAD(P)-bd_dom_sf       
IPR033640   FAR_C       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

H9JNN6   H9JNN4   H9JNM2   H9JWY2   A0A2A4JYT4   A0A2W1B8Q0   + More
A0A2A4JY42   A0A2A4K1U6   A0A2A4K1F7   A0A2H1VAJ7   A0A2H1VWV0   A0A0P0ELA9   A0A2W1BFX3   A0A2A4K2D3   A0A2A4J5Y0   A0A2A4JG81   A0A2W1BH40   A0A2A4JIF6   A0A2W1BUR6   A0A2A4JY41   A0A2W1BRZ8   A0A2H1WT26   A0A2W1BEZ6   A0A291P0Q6   A0A194PSN1   A0A194R4R4   A0A212ER01   A0A194PZ57   A0A194QZH1   A0A0N1PK47   U5KFQ5   A0A194PV95   A0A0P0EM43   A0A2W1BAL1   A0A1V0M874   A0A2W1BC59   A0A2W1BH51   A0A0F6Q1J7   A0A194PTV2   A0A0F6Q2N3   A0A068FK94   A0A2A4JS90   A0A2H1VVN7   A0A194PT03   A0A2H1VVB2   A0A212F0D5   A0A0N1I9W9   H9JNP1   B6SDB1   N6TBL5   U4UBB5   A0A0N0PFV2   A0A067R2Y2   A0A0F6NS76   A0A2J7RN95   A0A1Y1LHX9   A0A336L0D6   A0A1J1J054   K7J6N4   A0A151XFK4   A0A2J7RNB9   A0A0J7L758   A0A232EYC4   A0A1B0GID8   A0A3L8DXX4   E2AWD8   A0A195EE25   A0A158NHD8   K7J6N1   D2A5E7   A0A195BRC5   A0A1Y1K3T9   A0A158P2S4   A0A1B0CRM9   A0A2J7QR94   A0A232F2D0   K7J7I4   F4WU72   A0A0A9XGI9   A0A146LDG8   A0A068FRD3   A0A0A9WBX3   A0A0C9PMV0   F4W5T8   E2BCH8   E2AWD9   A0A195DFI7   K7J7I5   A0A0L0BW16   A0A1B6DYP0   A0A1B6DLK7   A0A151X2I2   A0A1B6CR01   A0A195C2N5   A0A195EZP6   A0A232EN92   A0A336LP21   E2AKQ3   A0A1I8P794  

PDB

4W4T     E-value=1.20338e-09,     Score=149

KEGG

101742447    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) fatty acyl-CoA reductase 1-

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0006629   GO:0102965   GO:0080019   GO:0016021   GO:0010025   GO:0005777   GO:0035336  

PANTHER

PTHR11011  

Length:

271

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.18086

Exp number, first 60 AAs:

0.18079

Total prob of N-in:

0.01401

outside

1  -  271

 

 

Pi

3.549399

Theta

4.484745

Tajima's D

-1.26905

CLR

1.392019

CSRT

0.0896955152242388

Interpretation

Uncertain