Gene

KWMTBOMO14197

Pre Gene Modal

BGIBMGA011140

Annotation

PREDICTED:_fatty_acyl-CoA_reductase_1-like_[Bombyx_mori]

Location

Bomo_Chr23(+):20278702-20288420      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

PlasmaMembrane   Reliability : 3.085

CDS

ATGGACAGCGCTTTGGCTTTGGAGATCGAGCAGGTCTCGCGCCAGAAGGCGCTGGAGGAGGAAGCGCTCCGCGGCGAGTCGGCTGTGCGGCAGTTCTACGCGGGAACCACAGCGCTGATCACTGGAGGGACGGGCTTCATCGGGAAACAACTCATAGAGAAGCTTCTAAGATCGTGCGACGTTAAGCGGATTTACATATTGGCACGATCGAAAAAGGGACTGTCTATGGAAGAAAGGCTCCAGTTACAATTTAAAGATCCTGTATACGACAATTTACGGTCTCAACAACCAGATTTCGCTCAGAAAGTGATACCGGTCGAAGGTGACATCTCAGAACTAGGCGTCGGCTTGAACGACGAAGACAGGATGAAGCTTGAGCAAGAGGTGAATGTGATATTCCACGTGGCCGCCACGACCAGGTTCGTAGAGCCACTGAAGAAGGCCACATTCATCAACGTCAGAGGAACCAGAGAGATCCTTGAACTGGCCAAATGCTGTAAAAATCTAAGATGCTTCGTACACGTATCAACTGCGTTCTTCAATGCAACAAAGAGCAAAATAAATCACACCATCGAGGAGAAATTCTATGAAAGCCCTGTCCCTCCGGAAGTCATGATACAACTCGCGGAGACAGTTGAAGAATGCAGACTCAACGCGATCACTGCTGATTTGATAAGGGACTGGCCCAACACGTACTGCTTCACGAAGGCCATAGCCGAGGATGTCGTGCGTACAATGGGCAAGGATTTACCTGTGGCCATAGTGAGGCCACCCATAGTTATCTGCACGCTCAATGAACCCACACCTGGATGGGTGGATATAAGCTCAGTGTTCGGTCCCAGCGGGATTCTTTTAGGCATAGGCCTTGGCGTGACGCATGTGGTTTTAATAGGTGACATAACGATAGCGCTAGCTCCTGTGGACTACGTCAACAACACTGTATTGGCGACAGCGTGGGAAACCGATAAACGTTTTAAAAATAATGAAAAAGACTCTAAGATTTACAATATAAGCAACTCCAGATGCACACTTGAGAAAAATCTCGTGGGTGATCTCCTGCAGAATCCTAACACACAACAGTACGCTACGCCGAAAGCGGTTTGGTACTGTTATGGTTTTGAGACCGGAAGCGATGTTGTATTCTGGTTGTCAACGTGGCTGCTGCATTACATACCTGCGTATGTAGCCGACTTCGTGTTTAATGTGACCTCCATGAAGCGACCTGAGGGTATTAAGTCATTCGTTAAAATGTATGAAAAGATATACAAAATGTCTTTGTTGTACGGCTATTTCCTGAGGAACCAGTGGAATCTTGTCGATGACAACACCGTGGCCATGCTGAACCAAATGTCAAAAACTGACAGGATATTGTTCAATTTTGACATTTCGAAGATCGATTGGCCGCGCTATATGCTGATCTGGTGCATCGGCTTGAGAAAGTTCATCGTGAAAGACGGACTCAAAGACAGCGAGTATGGAATGAAGAAACAGAGATGGCTGAAGATAGCTCACATTAGTTTTTATACGCTGTTCTTTGGAGTCGTATTTTCTTTGTTATATCTCGCCTGTAGAATTTTTATGTACTTATGTAATTTGAATACGATCGCCGCTCAAACACTTAAAATATAA

Protein

MDSALALEIEQVSRQKALEEEALRGESAVRQFYAGTTALITGGTGFIGKQLIEKLLRSCDVKRIYILARSKKGLSMEERLQLQFKDPVYDNLRSQQPDFAQKVIPVEGDISELGVGLNDEDRMKLEQEVNVIFHVAATTRFVEPLKKATFINVRGTREILELAKCCKNLRCFVHVSTAFFNATKSKINHTIEEKFYESPVPPEVMIQLAETVEECRLNAITADLIRDWPNTYCFTKAIAEDVVRTMGKDLPVAIVRPPIVICTLNEPTPGWVDISSVFGPSGILLGIGLGVTHVVLIGDITIALAPVDYVNNTVLATAWETDKRFKNNEKDSKIYNISNSRCTLEKNLVGDLLQNPNTQQYATPKAVWYCYGFETGSDVVFWLSTWLLHYIPAYVADFVFNVTSMKRPEGIKSFVKMYEKIYKMSLLYGYFLRNQWNLVDDNTVAMLNQMSKTDRILFNFDISKIDWPRYMLIWCIGLRKFIVKDGLKDSEYGMKKQRWLKIAHISFYTLFFGVVFSLLYLACRIFMYLCNLNTIAAQTLKI

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Feature

chain  Fatty acyl-CoA reductase

Uniprot

H9JWY2   H9JNM2   A0A2A4JYT4   A0A2A4K1F7   A0A2W1BUR6   A0A291P0Q6   + More
A0A2W1BEZ6   A0A2H1VWV0   A0A2W1B8Q0   A0A2W1BRZ8   A0A2W1BFX3   A0A0P0ELA9   A0A2A4JY41   A0A0N1PK47   A0A2A4J5Y0   A0A2W1BH40   A0A212ER01   A0A2H1WT26   A0A194PSN1   A0A194PV95   A0A194PZ57   A0A194R4R4   A0A2W1BAL1   A0A2A4K1U6   A0A2A4JY42   A0A2A4K2D3   A0A2A4JG81   A0A0P0EM43   A0A1V0M874   H9JNP1   A0A212F0D5   A0A2W1BH51   A0A0F6Q2N3   A0A0F6Q1J7   A0A068FK94   A0A194PTV2   A0A067R2Y2   A0A194PT03   A0A068FRD3   K7J6N4   A0A2J7RNB9   U4UBB5   A0A232EYC4   N6TBL5   D9D5H5   A0A0N1I9W9   A0A0C9PMV0   A0A146LDG8   A0A0A9XGI9   A0A1J1J054   A0A1V0M882   A0A2S2QSR0   A0A193CHN6   A0A2A4K2M9   A0A2W1BMW7   A0A2J7QR94   A0A195BRC5   A0A2H8U048   A0A3Q8FLY7   A0A0F6Q2Q6   A0A0P0EGI7   A0A194RHP3   A0A1B0CRM9   D2A5E7   A0A2S2QPP2   A0A1B6DLK7   A0A1B6KC16   A0A1B6CR01   A0A1B6I9B4   A0A195D4N2   J9K0H2   A0A151XFK4   A0A336L0D6   A0A0M9ABB1   A0A2S2PN15   K7J7I5   A0A1B6IV08   A0A158NHD8   A0A1B6EVR8   J9JN47   A0A1B6EEG7   A0A0L0BW16   A0A2H8TIW3   T1HHV9   A0A067QQS7   A0A3M7QWY4   A0A1Y1K3T9   D2A5T7   A0A1B6KTN1   F4WU72   A0A1J1IJD8  

EC Number

1.2.1.84

Pubmed

19121390    28756777    28986331    26445454    26354079    22118469    + More
28349297    26385554    24845553    20075255    23537049    28648823    26823975    25401762    27271970    18362917    19820115    21347285    26108605    30375419    28004739    21719571   

EMBL

BABH01042202    BABH01042203    BABH01042204    BABH01035129    BABH01035130    BABH01035131    + More
BABH01035132    NWSH01000368    PCG76936.1    NWSH01000263    PCG77899.1    KZ149959    PZC76396.1    MF687542    ATJ44468.1    KZ150147    PZC72871.1    ODYU01004617    SOQ44684.1    KZ150217    PZC72129.1    PZC76395.1    PZC72127.1    KT261699    ALJ30239.1    PCG76937.1    KQ460036    KPJ18429.1    NWSH01003107    PCG66934.1    PZC72126.1    AGBW02013183    OWR43905.1    ODYU01010853    SOQ56210.1    KQ459593    KPI96441.1    KPI96679.1    KPI96440.1    KQ460890    KPJ10851.1    PZC72128.1    PCG77898.1    PCG76935.1    NWSH01000230    PCG78176.1    NWSH01001490    PCG71095.1    KT261695    ALJ30235.1    KU755476    ARD71186.1    BABH01035163    BABH01035164    AGBW02011118    OWR47192.1    PZC72130.1    KP237913    MF687534    AKD01766.1    ATJ44460.1    KP237926    MF687596    AKD01779.1    ATJ44522.1    KJ622061    AID66649.1    KPI96403.1    KK852740    KDR17399.1    KPI96442.1    KJ622062    AID66650.1    NEVH01002545    PNF42309.1    KB632003    ERL87876.1    NNAY01001641    OXU23345.1    APGK01044237    APGK01044238    KB741021    ENN75098.1    GU808251    ADI82775.1    KPJ18430.1    GBYB01002483    JAG72250.1    GDHC01012276    JAQ06353.1    GBHO01025676    JAG17928.1    CVRI01000065    CRL05837.1    KU755485    ARD71195.1    GGMS01011572    MBY80775.1    KU963289    ANN23959.1    PCG77902.1    PZC76399.1    NEVH01011924    PNF31087.1    KQ976417    KYM89582.1    GFXV01007576    MBW19381.1    MG573160    AWJ25022.1    KP237938    MF687591    AKD01791.1    ATJ44517.1    KT261704    ALJ30244.1    KQ460152    KPJ17348.1    AJWK01024997    AJWK01024998    AJWK01024999    KQ971345    EFA05090.1    GGMS01010440    MBY79643.1    GEDC01010770    JAS26528.1    GEBQ01030984    JAT08993.1    GEDC01021312    JAS15986.1    GECU01024246    JAS83460.1    KQ976870    KYN07801.1    ABLF02017921    KQ982194    KYQ59115.1    UFQS01001285    UFQT01001285    SSX10116.1    SSX29838.1    KQ435694    KOX80980.1    GGMR01018223    MBY30842.1    GECU01016929    JAS90777.1    ADTU01015701    ADTU01015702    GECZ01027740    JAS42029.1    ABLF02012968    GEDC01000976    JAS36322.1    JRES01001250    KNC24227.1    GFXV01002241    MBW14046.1    ACPB03001017    KK853504    KDR07123.1    REGN01004851    RNA15897.1    GEZM01093770    JAV56139.1    EFA05024.1    GEBQ01025216    JAT14761.1    GL888353    EGI62240.1    CVRI01000054    CRL00357.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000027135    + More
UP000002358    UP000235965    UP000030742    UP000215335    UP000019118    UP000183832    UP000078540    UP000092461    UP000007266    UP000078542    UP000007819    UP000075809    UP000053105    UP000005205    UP000037069    UP000015103    UP000276133    UP000007755   

PRIDE

H9JWY2    H9JNM2    H9JNP1   

Pfam

PF03015   Sterile        + More
PF07993   NAD_binding_4

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR013120   Male_sterile_NAD-bd       
IPR033640   FAR_C       
IPR026055   FAR       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

H9JWY2   H9JNM2   A0A2A4JYT4   A0A2A4K1F7   A0A2W1BUR6   A0A291P0Q6   + More
A0A2W1BEZ6   A0A2H1VWV0   A0A2W1B8Q0   A0A2W1BRZ8   A0A2W1BFX3   A0A0P0ELA9   A0A2A4JY41   A0A0N1PK47   A0A2A4J5Y0   A0A2W1BH40   A0A212ER01   A0A2H1WT26   A0A194PSN1   A0A194PV95   A0A194PZ57   A0A194R4R4   A0A2W1BAL1   A0A2A4K1U6   A0A2A4JY42   A0A2A4K2D3   A0A2A4JG81   A0A0P0EM43   A0A1V0M874   H9JNP1   A0A212F0D5   A0A2W1BH51   A0A0F6Q2N3   A0A0F6Q1J7   A0A068FK94   A0A194PTV2   A0A067R2Y2   A0A194PT03   A0A068FRD3   K7J6N4   A0A2J7RNB9   U4UBB5   A0A232EYC4   N6TBL5   D9D5H5   A0A0N1I9W9   A0A0C9PMV0   A0A146LDG8   A0A0A9XGI9   A0A1J1J054   A0A1V0M882   A0A2S2QSR0   A0A193CHN6   A0A2A4K2M9   A0A2W1BMW7   A0A2J7QR94   A0A195BRC5   A0A2H8U048   A0A3Q8FLY7   A0A0F6Q2Q6   A0A0P0EGI7   A0A194RHP3   A0A1B0CRM9   D2A5E7   A0A2S2QPP2   A0A1B6DLK7   A0A1B6KC16   A0A1B6CR01   A0A1B6I9B4   A0A195D4N2   J9K0H2   A0A151XFK4   A0A336L0D6   A0A0M9ABB1   A0A2S2PN15   K7J7I5   A0A1B6IV08   A0A158NHD8   A0A1B6EVR8   J9JN47   A0A1B6EEG7   A0A0L0BW16   A0A2H8TIW3   T1HHV9   A0A067QQS7   A0A3M7QWY4   A0A1Y1K3T9   D2A5T7   A0A1B6KTN1   F4WU72   A0A1J1IJD8  

PDB

4W4T     E-value=2.07191e-10,     Score=159

KEGG

101742447    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) fatty acyl-CoA reductase 1-

GO

GO:0102965   GO:0080019   GO:0006629   GO:0016021   GO:0010025   GO:0005777   GO:0035336  

PANTHER

PTHR11011  

Length:

542

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

47.3686

Exp number, first 60 AAs:

1.53592

Total prob of N-in:

0.14370

outside

1  -  503

TMhelix

504  -  526

inside

527  -  542

 

 

Pi

3.939364

Theta

16.745876

Tajima's D

-1.623655

CLR

0.077277

CSRT

0.0442977851107445

Interpretation

Uncertain