Gene

KWMTBOMO14180

Pre Gene Modal

BGIBMGA011098

Annotation

PREDICTED:_brain-specific_homeobox_protein_homolog_[Bombyx_mori]

Location

Bomo_Chr23(-):19915923-19921171      View in EpiBrowser

Full name

Brain-specific homeobox protein homolog      

Transcription factor

Homeobox

Location in the cell

Nuclear   Reliability : 3.979

CDS

ATGGAACACGAGACTCGAAGCGATTCGCCAACAACAAATTCAAATCGTCCGGAACACAATTCAAAAACTTCATTCCTCATAGAAGACATACTTTATAGAGGCGACAATCGATTTAAAGTTCCCAATGTCGAACGAAGACTCGACTACGAGCCGCGGCCTTACTTCTCCGTGGCTGGCGACGTCAGGCCTCACCAGACCAGGGAAGGGTATCTGCAGGTCGCCATGGGAGCCCTAGGCGCTTACCTGCACACCCCCAATACGTATAAAGCAGTCGAACCACCTTATTTTTTGTCGCAAGGTGTGCCGTATCACGCTTTGTTCACGCCTTCGGAGCTATCGCTGTCTGCGCTAAAGCACTGCAGACGACGGAAGGCCAGAACAGTCTTCTCGGACCCTCAACTAACAGGTCTGGAGAAACGGTTCGAGTCGCAGCGCTACCTTTCGACTCCTGAGCGAGTTGAGTTAGCAGGAGCGCTGAACCTCTCCGAAACCCAGGTGAAGACGTGGTTCCAGAACCGACGGATGAAGCACAAGAAGCTGATGAGGAAGCAACAGCAGCAGAGGAGTAAGACGTTTTGCTGGGCTATTAGAAAATCGATTTTGAAATGA

Protein

MEHETRSDSPTTNSNRPEHNSKTSFLIEDILYRGDNRFKVPNVERRLDYEPRPYFSVAGDVRPHQTREGYLQVAMGALGAYLHTPNTYKAVEPPYFLSQGVPYHALFTPSELSLSALKHCRRRKARTVFSDPQLTGLEKRFESQRYLSTPERVELAGALNLSETQVKTWFQNRRMKHKKLMRKQQQQRSKTFCWAIRKSILK

Description

DNA binding protein that function as transcriptional activator. May play a role in the determination and function of cell types in the brain.

Similarity

Belongs to the distal-less homeobox family.

Keywords

Activator   Complete proteome   DNA-binding   Homeobox   Nucleus   Reference proteome   Transcription   Transcription regulation  

Feature

chain  Brain-specific homeobox protein homolog

Uniprot

H9JNJ4   A0A2A4JLY4   A0A212F600   A0A194PTP7   D2A4M9   A0A2W1BV11   + More
A0A3S2LW32   N6T6E4   U4UAB5   A0A1W4W9T9   A0A1S3DAX0   A0A1B0GQU0   E0W139   A0A2H8TU62   J9JL05   A0A2H8TNS0   A0A384BAR2   A0A2S2NRW2   A0A3B4CSD0   A0A2Y9FRD4   A0A151NQA9   A0A1S3ELZ1   A0A2U4BVR5   G1U5N1   A0A341B3X3   A0A340XDI7   A0A2Y9MFR8   A0A2D0SP10   A0A3B3HB99   A0A3Q3JXE3   G1SI27   A0A3P9HPA4   A0A2K5DF78   E1BAF5   A0A384C0N1   G5BS01   H0UXW7   I3NDB2   G3TDR4   A0A226NEH6   A0A0L7K2K3   A0A1S3A402   L5JT80   F1S9Q4   G1PX86   A0A3B1JNL2   A0A2K5QXG3   A0A226PP52   Q6RFL5   M3W5J1   A0A3L7HS93  

Pubmed

19121390    22118469    26354079    18362917    19820115    28756777    + More
23537049    20566863    22293439    21993624    17554307    19393038    21993625    26227816    23258410    25329095    24621616    17975172    29704459   

EMBL

BABH01041266    BABH01041267    BABH01041268    NWSH01001078    PCG72728.1    AGBW02010104    + More
OWR49162.1    KQ459593    KPI96348.1    KQ971344    EFA05724.1    KZ149991    PZC75593.1    RSAL01000156    RVE45600.1    APGK01050589    KB741174    ENN73248.1    KB632260    ERL90834.1    AJVK01001901    AJVK01001902    DS235866    EEB19345.1    GFXV01005546    MBW17351.1    ABLF02020893    GFXV01003103    MBW14908.1    GGMR01007199    MBY19818.1    AKHW03002395    KYO39016.1    AAGW02009545    JH171573    EHB12062.1    AAKN02024753    AGTP01053122    MCFN01000082    OXB65760.1    JTDY01014421    KOB52031.1    KB031151    ELK01408.1    AEMK02000070    AAPE02051268    AWGT02000038    OXB81282.1    AY500594    AAR89086.1    AANG04000369    RAZU01000159    RLQ68778.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000007266    UP000283053    + More
UP000019118    UP000030742    UP000192223    UP000079169    UP000092462    UP000009046    UP000007819    UP000261681    UP000261440    UP000248484    UP000050525    UP000081671    UP000245320    UP000001811    UP000252040    UP000265300    UP000248483    UP000221080    UP000001038    UP000261600    UP000265200    UP000233020    UP000009136    UP000261680    UP000006813    UP000005447    UP000005215    UP000007646    UP000198323    UP000037510    UP000079721    UP000010552    UP000008227    UP000001074    UP000018467    UP000233040    UP000198419    UP000000539    UP000011712    UP000273346   

PRIDE

H9JNJ4    E1BAF5    F1S9Q4   

Pfam

PF00046   Homeodomain        + More
PF13855   LRR_8

Interpro

IPR001356   Homeobox_dom        + More
IPR017970   Homeobox_CS       
IPR020479   Homeobox_metazoa       
IPR009057   Homeobox-like_sf       
IPR032675   LRR_dom_sf       
IPR000483   Cys-rich_flank_reg_C       
IPR001611   Leu-rich_rpt       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR000047   HTH_motif       

SUPFAM

SSF46689   SSF46689       

Gene 3D

3.80.10.10    

CDD

cd00086  homeodomain

ProteinModelPortal

H9JNJ4   A0A2A4JLY4   A0A212F600   A0A194PTP7   D2A4M9   A0A2W1BV11   + More
A0A3S2LW32   N6T6E4   U4UAB5   A0A1W4W9T9   A0A1S3DAX0   A0A1B0GQU0   E0W139   A0A2H8TU62   J9JL05   A0A2H8TNS0   A0A384BAR2   A0A2S2NRW2   A0A3B4CSD0   A0A2Y9FRD4   A0A151NQA9   A0A1S3ELZ1   A0A2U4BVR5   G1U5N1   A0A341B3X3   A0A340XDI7   A0A2Y9MFR8   A0A2D0SP10   A0A3B3HB99   A0A3Q3JXE3   G1SI27   A0A3P9HPA4   A0A2K5DF78   E1BAF5   A0A384C0N1   G5BS01   H0UXW7   I3NDB2   G3TDR4   A0A226NEH6   A0A0L7K2K3   A0A1S3A402   L5JT80   F1S9Q4   G1PX86   A0A3B1JNL2   A0A2K5QXG3   A0A226PP52   Q6RFL5   M3W5J1   A0A3L7HS93  

PDB

2DMT     E-value=1.45325e-14,     Score=190

KEGG

101737446    no KO assigned | (RefSeq) brain-specific homeobox protein homolog

GO

GO:0005634   GO:0043565   GO:0006355   GO:0016021   GO:0000978   GO:0003700   GO:0006357   GO:0003677   GO:0021982   GO:0060056   GO:0007626   GO:0045944   GO:0042755   GO:0005667   GO:0007420   GO:0009982   GO:0005488   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

Subcellular location

Nucleus  

Length:

202

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.17792

Exp number, first 60 AAs:

0

Total prob of N-in:

0.12346

outside

1  -  202

 

 

Pi

18.804861

Theta

19.828557

Tajima's D

-0.72027

CLR

14.456008

CSRT

0.194240287985601

Interpretation

Uncertain