Gene

KWMTBOMO14175

Annotation

PREDICTED:_tRNA_pseudouridine(38/39)_synthase_[Bombyx_mori]

Location

Bomo_Chr23(+):19797160-19803161      View in EpiBrowser

Full name

tRNA pseudouridine synthase      

Location in the cell

Nuclear   Reliability : 3.074

CDS

ATGGAAAAACTGCCACCAAAACAGAAGATTAACCGGAACGCAACAAGAGAGGAACTTTTAAAGTTGGACAAAAATGATCTCGTCGAGAAAATAATACAGTTGCAAGCCCATAATACACAGCTGAAAAACATCATAAATAAAACTACACCTTGCGATGGCCAAAAGCAGAAAAAAGTAGACCAAAGAGAATTTATGTTTGAAAAATGCCATTATCGTCATGTCCTCCTAAGGGTATCGTACCTTGGCTGGGAATATCAAGGTCTGGCTGTACAGGAGAATACAACACAAACAGTAGAATATCATCTTTTTGAAGCCTTGAAAAGGGCCTGTTTGATACAAAGCCGTGAAACCTCTAATTATCACCGATGTGGTCGTACAGACAAGGGAGTTAGCTCATTTGGGCAGGTCATATCGATATGCCTAAGGAGTAAACATTCACCGGAGGAACAAAACAAACCGAGCTGCATTAGAAATGAGATTCCGTATAGTAAATTGTTGAATCGTCTGTTGCCCAAACATATAAAGGTTATTGCTTGGATGCCAATACCGCAGGACAGACCGGATTTCAGTGCACGATTCGATTGTAAAAAACGTTCCTACAAATATTATTTCCCACACTCCGGGCTGAACCTGCCCGCCATGCTGGAAGCGTGCCGTCACATGATCGGGTCGCACGATTTCCGCCATCTCTGTAAAATGGACGTCGGTAATGGTGTATTGGAATTTATAAGAAGAATAATGAATGTTGACATCGTACCTGTCGATGTTAATGATGTTGACAAACCAACATCAATGTACTATCTGCTGATAGAAGGAAACGCATTTCTGTGGCATCAGATACGTTGCATTATGGGTGTCTTACTGCTGATAGGAGAAGAAAAAGAAAGACCTGACGTGGTGTTAGAATTGTTGGACGTTGAGAAGAATCGGGGAAAACCGCAATACAGCATGGCGTCTGACCTCCCGTTGAATTTGTTCAAATGTGCGTACGAGATAGAAGATACCAATCGATGGGTGTACGAAAGAGAAGCACTGATCACTCTCATATCTGATCTGAGAACGGAATGGACTATGCACGCCGTCAAGACAACGATGATTCAAGATTACATACGCGAGCTAGAAAAGGTCCCTCTGGCGAGCGAGACGGAAGACAGGGCCAATGACGAGTGCGAGCAAGATGAAATCGCATCGTACGCGGCGTGCTTGCTGCAAGGGGTGAAACCGAAAAATTACACTCCATTGATGAAAAGACCCACATGTTCAACGCTACACGAGAAGATTGCGCATTACAAGAAGAGACGGAAGATAATAACAAGCTAA

Protein

MEKLPPKQKINRNATREELLKLDKNDLVEKIIQLQAHNTQLKNIINKTTPCDGQKQKKVDQREFMFEKCHYRHVLLRVSYLGWEYQGLAVQENTTQTVEYHLFEALKRACLIQSRETSNYHRCGRTDKGVSSFGQVISICLRSKHSPEEQNKPSCIRNEIPYSKLLNRLLPKHIKVIAWMPIPQDRPDFSARFDCKKRSYKYYFPHSGLNLPAMLEACRHMIGSHDFRHLCKMDVGNGVLEFIRRIMNVDIVPVDVNDVDKPTSMYYLLIEGNAFLWHQIRCIMGVLLLIGEEKERPDVVLELLDVEKNRGKPQYSMASDLPLNLFKCAYEIEDTNRWVYEREALITLISDLRTEWTMHAVKTTMIQDYIRELEKVPLASETEDRANDECEQDEIASYAACLLQGVKPKNYTPLMKRPTCSTLHEKIAHYKKRRKIITS

Catalytic Activity

tRNA uridine(38-40) = tRNA pseudouridine(38-40)

Similarity

Belongs to the tRNA pseudouridine synthase TruA family.

Uniprot

A0A3S2NK40   A0A194PSU4   A0A2A4K4U0   A0A2H1VPP1   A0A212FF28   A0A194RHN8   + More
Q17C60   A0A182H2W5   A0A1S4F8E1   K7ILU7   A0A1B0CKV8   W5JGD2   Q7Q242   A0A182X0G3   A0A182YIY5   B0XGH8   U5EYI7   A0A182FV58   A0A182Q2G0   A0A232F1G6   A0A182NV92   A0A182RQS9   A0A2J7PY20   A0A182TUH6   A0A1Q3F0W6   A0A182W9I4   F4WM06   A0A182MGW1   A0A1B6CQ65   A0A2J7PY35   A0A2J7PY36   A0A182JRV9   A0A182U7Z7   A0A067R7W5   A0A182I5Q3   A0A182JE61   A0A182KVC2   A0A182TAS2   A0A158N9D1   A0A1J1HII5   A0A0C9RNL3   A0A3B0IYD2   A0A1Y1MER1   E9J363   B3MIG8   A0A1I8N500   A0A195C649   A0A151XA63   A0A1I8QEN3   A0A182P1V9   A0A088AAQ4   A0A0K8TKH5   A0A195DDZ6   A0A195FW48   D2A375   Q28WM9   N6UJE4   B4P7E9   A0A182V7T2   A0A0C9QVE6   A0A0L7QYD6   B4KMH4   A0A084VE99   B4NSM9   B4LNF7   A0A0A1WJ33   A0A1A9WIV0   A0A0M4ELH1   W8C3R7   A0A1A9V687   A0A034WV69   A0A1B0G7L7   A0A1W4UMH0   Q9W282   N6TMX4   B3NND9   A0A0K8V9W7   A0A0K8V5I5   A0A195BD54   A0A1B6L6E9   E9GYG4   A0A162CYX9   A0A0P5TAS3   B4MNT4   A0A0N8E7F6   A0A1B6I341   A0A1B6EJJ1   A0A1A9ZPL9   A0A0P4ZD64   A0A0C9Q1B3   E2B8R8   A0A1S3JIJ6   A0A0N0BJU6   A0A1B0B7B8   A0A293MEK8   A0A1A9YCV4   A0A1S3JHR2   A0A0P6BIR9   A0A0P5XP54   A0A0A9WL21  

EC Number

5.4.99.-

Pubmed

26354079    22118469    17510324    26483478    20075255    20920257    + More
23761445    12364791    25244985    28648823    21719571    24845553    20966253    21347285    28004739    21282665    17994087    25315136    26369729    18362917    19820115    15632085    23537049    17550304    24438588    22936249    25830018    24495485    25348373    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18057021    21292972    20798317    25401762   

EMBL

RSAL01000062    RVE49578.1    KQ459593    KPI96382.1    NWSH01000181    PCG78682.1    + More
ODYU01003699    SOQ42793.1    AGBW02008879    OWR52307.1    KQ460152    KPJ17343.1    CH477311    EAT43931.1    JXUM01106247    JXUM01106248    KQ565036    KXJ71421.1    AJWK01016666    ADMH02001590    ETN61945.1    AAAB01008979    EAA13705.4    DS233032    EDS27642.1    GANO01001979    JAB57892.1    AXCN02001809    NNAY01001317    OXU24382.1    NEVH01020851    PNF21233.1    GFDL01013842    JAV21203.1    GL888217    EGI64650.1    AXCM01004473    GEDC01021642    JAS15656.1    PNF21236.1    PNF21234.1    KK852819    KDR15609.1    APCN01003485    ADTU01001377    CVRI01000004    CRK87715.1    GBYB01015102    JAG84869.1    OUUW01000001    SPP72757.1    GEZM01033276    JAV84292.1    GL768058    EFZ12740.1    CH902619    EDV37016.1    KQ978220    KYM96339.1    KQ982353    KYQ57168.1    GDAI01002746    JAI14857.1    KQ980989    KYN10639.1    KQ981264    KYN44064.1    KQ971338    EFA02961.2    CM000071    EAL26638.1    APGK01017607    KB740045    KB631729    ENN81865.1    ERL85628.1    CM000158    EDW92094.1    GBYB01007694    JAG77461.1    KQ414691    KOC63618.1    CH933808    EDW09862.1    ATLV01012262    KE524775    KFB36293.1    CH982367    CM002911    EDX15607.1    KMY95733.1    CH940648    EDW61109.1    GBXI01015899    JAC98392.1    CP012524    ALC42430.1    GAMC01005944    JAC00612.1    GAKP01001284    JAC57668.1    CCAG010016883    AE013599    AY058376    AAF46811.1    AAL13605.1    ENN81864.1    ERL85627.1    CH954179    EDV55563.1    GDHF01016628    JAI35686.1    GDHF01018127    JAI34187.1    KQ976519    KYM82120.1    GEBQ01020731    JAT19246.1    GL732575    EFX75483.1    LRGB01000024    KZS21369.1    GDIP01134849    JAL68865.1    CH963848    EDW73773.1    GDIQ01054420    JAN40317.1    GECU01026358    JAS81348.1    GECZ01031685    JAS38084.1    GDIP01214389    JAJ09013.1    GBYB01007693    JAG77460.1    GL446371    EFN87913.1    KQ435711    KOX79464.1    JXJN01009514    GFWV01013669    MAA38398.1    GDIP01028498    JAM75217.1    GDIP01081600    GDIQ01072416    JAM22115.1    JAN22321.1    GBHO01036397    GBHO01036396    JAG07207.1    JAG07208.1   

Proteomes

UP000283053    UP000053268    UP000218220    UP000007151    UP000053240    UP000008820    + More
UP000069940    UP000249989    UP000002358    UP000092461    UP000000673    UP000007062    UP000076407    UP000076408    UP000002320    UP000069272    UP000075886    UP000215335    UP000075884    UP000075900    UP000235965    UP000075902    UP000075920    UP000007755    UP000075883    UP000075881    UP000027135    UP000075840    UP000075880    UP000075882    UP000075901    UP000005205    UP000183832    UP000268350    UP000007801    UP000095301    UP000078542    UP000075809    UP000095300    UP000075885    UP000005203    UP000078492    UP000078541    UP000007266    UP000001819    UP000019118    UP000030742    UP000002282    UP000075903    UP000053825    UP000009192    UP000030765    UP000000304    UP000008792    UP000091820    UP000092553    UP000078200    UP000092444    UP000192221    UP000000803    UP000008711    UP000078540    UP000000305    UP000076858    UP000007798    UP000092445    UP000008237    UP000085678    UP000053105    UP000092460    UP000092443   

PRIDE

Q9W282   

Pfam

PF01416   PseudoU_synth_1        + More
PF00147   Fibrinogen_C
PF07776   zf-AD
PF00096   zf-C2H2
PF01694   Rhomboid

Interpro

IPR001406   PsdUridine_synth_TruA        + More
IPR020103   PsdUridine_synth_cat_dom_sf       
IPR020097   PsdUridine_synth_TruA_a/b_dom       
IPR041707   Pus3-like       
IPR020095   PsdUridine_synth_TruA_C       
IPR020837   Fibrinogen_CS       
IPR002181   Fibrinogen_a/b/g_C_dom       
IPR036056   Fibrinogen-like_C       
IPR013087   Znf_C2H2_type       
IPR036236   Znf_C2H2_sf       
IPR012934   Znf_AD       
IPR022764   Peptidase_S54_rhomboid_dom       
IPR035952   Rhomboid-like_sf       

SUPFAM

SSF55120   SSF55120        + More
SSF56496   SSF56496       
SSF57667   SSF57667       

Gene 3D

3.30.70.660     1.20.1540.10    

CDD

cd02569  PseudoU_synth_ScPus3
cd00087  FReD

ProteinModelPortal

A0A3S2NK40   A0A194PSU4   A0A2A4K4U0   A0A2H1VPP1   A0A212FF28   A0A194RHN8   + More
Q17C60   A0A182H2W5   A0A1S4F8E1   K7ILU7   A0A1B0CKV8   W5JGD2   Q7Q242   A0A182X0G3   A0A182YIY5   B0XGH8   U5EYI7   A0A182FV58   A0A182Q2G0   A0A232F1G6   A0A182NV92   A0A182RQS9   A0A2J7PY20   A0A182TUH6   A0A1Q3F0W6   A0A182W9I4   F4WM06   A0A182MGW1   A0A1B6CQ65   A0A2J7PY35   A0A2J7PY36   A0A182JRV9   A0A182U7Z7   A0A067R7W5   A0A182I5Q3   A0A182JE61   A0A182KVC2   A0A182TAS2   A0A158N9D1   A0A1J1HII5   A0A0C9RNL3   A0A3B0IYD2   A0A1Y1MER1   E9J363   B3MIG8   A0A1I8N500   A0A195C649   A0A151XA63   A0A1I8QEN3   A0A182P1V9   A0A088AAQ4   A0A0K8TKH5   A0A195DDZ6   A0A195FW48   D2A375   Q28WM9   N6UJE4   B4P7E9   A0A182V7T2   A0A0C9QVE6   A0A0L7QYD6   B4KMH4   A0A084VE99   B4NSM9   B4LNF7   A0A0A1WJ33   A0A1A9WIV0   A0A0M4ELH1   W8C3R7   A0A1A9V687   A0A034WV69   A0A1B0G7L7   A0A1W4UMH0   Q9W282   N6TMX4   B3NND9   A0A0K8V9W7   A0A0K8V5I5   A0A195BD54   A0A1B6L6E9   E9GYG4   A0A162CYX9   A0A0P5TAS3   B4MNT4   A0A0N8E7F6   A0A1B6I341   A0A1B6EJJ1   A0A1A9ZPL9   A0A0P4ZD64   A0A0C9Q1B3   E2B8R8   A0A1S3JIJ6   A0A0N0BJU6   A0A1B0B7B8   A0A293MEK8   A0A1A9YCV4   A0A1S3JHR2   A0A0P6BIR9   A0A0P5XP54   A0A0A9WL21  

PDB

1VS3     E-value=5.08412e-09,     Score=146

KEGG

101743948    K01855 tRNA pseudouridine38/39 synthase [EC:5.4.99.45] | (RefSeq) tRNA pseudouridine(38/39) synthase

GO

GO:0106029   GO:0008033   GO:0001522   GO:0003723   GO:0009982   GO:0005737   GO:0005634   GO:0031119   GO:1990481   GO:0008270   GO:0004252   GO:0016021   GO:0009451   GO:0005488   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

PANTHER

PTHR11142  

Length:

439

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03725

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01172

outside

1  -  439

 

 

Pi

29.039913

Theta

21.636458

Tajima's D

0.783962

CLR

0.544572

CSRT

0.608919554022299

Interpretation

Uncertain