Gene

KWMTBOMO14168  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011174

Annotation

PREDICTED:_sphingolipid_delta(4)-desaturase_DES1_[Papilio_xuthus]

Location

Bomo_Chr23(-):19662101-19681589      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 3.341

CDS

ATGGGTGCTAAAGTGTCTAGAACGGATTTCGAATGGGTTTATACGGAGGAGCCTCACGCTAGCCGCCGAAAAATAATTCTAGAGAAATATCCTGAGATCAAACAGTTGTTCGGCTATGATCCTCTTTTCAAATGGGTCGTGCTCAGTATGGTCCTGGCGCAGTTCGCGATGATGCCCATAGTCCAGCACCTGAGCTGGCCGATGACCCTGATTCTCGCCTACTGCTTCGGCGGAGTCATAAATCACTCTCTGATGCTTGCGATCCACGAGATAGCGCATAATCTAGCGTTCGGTCACAATCGCCCATTACACAACAGGCTATTCGGATTCTTCGCGAACCTCCCGATAGGCGTACCGATATCGATCAGCTTCAAGAAATACCATTTGGAACACCACAGGTACCAAGGAGACGAAGTTATAGATACTGATCTACCGACCCTGCTGGAAGCAAAACTGTTTTGCACGACGGGCGGGAAGCTGTGCTGGCTGTTCTTGCAGCCCTTCTTCTACGCCCTGAGGCCGCTCGTGGTCAGGCCAAAGCCGCCCACGCCCCTGGAGCTCATCAACCTGATCATTCAGCTGTTTTTCGACGCCGTCGTCGTGAAGCTGTTTGGTTGGAAGGTGCTGGGGTATTTGGTGTTTGGTTCGCTGATGGCGATGGGCGTCCATCCAGTGGCGGGTCATTTCATATCCGAGCACTACATGTTCAGGAAGGGCTTCGAAACGTATTCGTACTACGGGCCCCTGAACTGGATCACGTTCAACGTTGGCTACCACAACGAGCACCACGACTTTCCCGCGGTCCCAGGCCGGAGGCTGCCCGAGGTAAAACGCATAGCTTCGGAGTTCTATGACACGCTGCCTCAACACAATAGCTGGTCAAGCGTACTGTATGACTTCGTGATGGATCCTGAAATCGGTCCTTACGCCAGGATGAAAAGGAAGCACCACGGCCTAAAGAGCTAG

Protein

MGAKVSRTDFEWVYTEEPHASRRKIILEKYPEIKQLFGYDPLFKWVVLSMVLAQFAMMPIVQHLSWPMTLILAYCFGGVINHSLMLAIHEIAHNLAFGHNRPLHNRLFGFFANLPIGVPISISFKKYHLEHHRYQGDEVIDTDLPTLLEAKLFCTTGGKLCWLFLQPFFYALRPLVVRPKPPTPLELINLIIQLFFDAVVVKLFGWKVLGYLVFGSLMAMGVHPVAGHFISEHYMFRKGFETYSYYGPLNWITFNVGYHNEHHDFPAVPGRRLPEVKRIASEFYDTLPQHNSWSSVLYDFVMDPEIGPYARMKRKHHGLKS

Similarity

Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.

Uniprot

S4NTW3   A0A194PUI3   A0A0N1IBR5   A0A0U2F3C6   A0A1V0M859   A0A0P0EUM9   + More
A0A068FL45   A0A0M3L9M0   A0A1L8D6K0   F4WK44   A0A195C9F4   A0A151WZG4   A0A158NU25   A0A232EM57   J3JZJ8   U4UZD0   A0A195DJS5   A0A0L7QQN3   D2A4B6   A0A154PG59   K7J7E6   E2BYS5   A0A0J7L0W1   A0A026X049   A0A182LVN0   A0A1Y1N0K7   U5EVM8   A0A0C9QPJ5   A0A182Q6A3   A0A182N3S0   A0A084WI92   A0A1W4XBA7   A0A151I510   A0A2A3EA26   E2AQB5   A0A2P8ZC12   A0A182KFW3   A0A182RAH5   A0A0M4E023   A0A182YC85   A0A0L0C609   A0A1L8DYD9   W6AC26   A0A182IVI4   A0A182WD40   B4KGG4   A0A0A1X6P5   B4MUZ5   A0A0M9A5R4   Q16KB1   A0A2J7PLZ8   A0A182UQS6   A0A2M4BUA5   A0A2M4BU34   B4LR75   A0A2M3Z247   A0A182U767   A0A182KT82   A0A182X060   A0A182HPL9   A0A1Y9G890   W5JE68   A0A182P1G2   A0A2M4AE01   A0A023EQQ3   B4Q454   W8BT89   B4NZS7   Q94515   A0A1W4UBA5   B4JC21   A0A3B0JVI8   B3MMQ3   Q29PM1   A0A1Q3FHR6   B4I1N5   B3N5A3   A0A1I8N8N2   B0XIJ3   A0A0K8W533   A0A067R925   A0A023F8Z7   A0A1A9Z9E4   D3TPD7   A0A1L8EFN4   A0A1A9Y516   A0A1B0AWY5   A0A224XNM3   R4G5H9   A0A1A9UYB0   A0A1I8NTX7   A0A0V0G5D3   E0VSV1   R4WRN7   A0A1B6HT95   A0A0K8TSN4   A0A1A9VZS1   A0A1S3D9P6   A0A1B6FM57   A0A1B6LGA4  

Pubmed

23622113    26354079    28349297    26445454    26385554    21719571    + More
21347285    28648823    22516182    23537049    18362917    19820115    20075255    20798317    24508170    28004739    24438588    29403074    25244985    26108605    17994087    25830018    17510324    20966253    20920257    23761445    24945155    26483478    22936249    24495485    17550304    9003299    10731132    12537568    12537572    12537573    12537574    11937514    16110336    17569856    17569867    26109357    26109356    15632085    25315136    24845553    25474469    20353571    20566863    23691247    26369729   

EMBL

GAIX01012061    JAA80499.1    KQ459593    KPI96409.1    KQ460036    KPJ18423.1    + More
KP008127    AKU76414.1    KU755472    ARD71182.1    KT261691    ALJ30231.1    KJ622050    AID66658.1    KM366797    AIM40227.1    GEYN01000132    JAV01997.1    GL888193    EGI65416.1    KQ978143    KYM96743.1    KQ982638    KYQ53283.1    ADTU01026246    NNAY01003420    OXU19440.1    APGK01052850    BT128680    KB741216    AEE63637.1    ENN72475.1    KI207957    KI208180    ERL95766.1    ERL95809.1    KQ980794    KYN13072.1    KQ414786    KOC60938.1    KQ971348    EFA05646.1    KQ434896    KZC10777.1    AAZX01000325    GL451506    EFN79175.1    LBMM01001465    KMQ96271.1    KK107054    EZA61627.1    AXCM01006032    GEZM01021205    JAV89087.1    GANO01001808    JAB58063.1    GBYB01005544    JAG75311.1    AXCN02001100    ATLV01023923    KE525347    KFB49936.1    KQ976445    KYM86039.1    KZ288325    PBC28026.1    GL441721    EFN64373.1    PYGN01000110    PSN54010.1    CP012523    ALC38341.1    JRES01000864    KNC27686.1    GFDF01002640    JAV11444.1    KF835696    AHI54576.1    CH933807    EDW12160.1    GBXI01007882    JAD06410.1    CH963857    EDW76340.1    KQ435747    KOX76503.1    CH477969    CH477928    EAT34745.1    EAT34994.1    NEVH01024421    PNF17361.1    GGFJ01007453    MBW56594.1    GGFJ01007455    MBW56596.1    CH940649    EDW63539.1    GGFM01001851    MBW22602.1    APCN01003265    ADMH02001408    ETN62652.1    GGFK01005694    MBW39015.1    JXUM01075128    JXUM01075129    GAPW01002647    JAC10951.1    CM000361    CM002910    EDX03887.1    KMY88426.1    GAMC01001985    JAC04571.1    CM000157    EDW88861.1    AE014134    AY061196    AF466379    X94180    AAF52318.1    AAL28744.1    AAM12535.1    CAA63889.1    CH916368    EDW03034.1    OUUW01000010    SPP86084.1    CH902620    EDV31944.1    CH379058    EAL34272.1    GFDL01007992    JAV27053.1    CH480820    EDW54442.1    CH954177    EDV57933.1    DS233313    EDS29392.1    GDHF01006673    GDHF01006145    JAI45641.1    JAI46169.1    KK852807    KDR16071.1    GBBI01000790    JAC17922.1    CCAG010020379    EZ423289    ADD19565.1    GFDG01001301    JAV17498.1    JXJN01004961    GFTR01005008    JAW11418.1    ACPB03004426    GAHY01000555    JAA76955.1    GECL01003575    JAP02549.1    DS235758    EEB16457.1    AK417357    BAN20572.1    GECU01029802    JAS77904.1    GDAI01000226    JAI17377.1    GECZ01021187    GECZ01018518    JAS48582.1    JAS51251.1    GEBQ01017319    JAT22658.1   

Proteomes

UP000053268    UP000053240    UP000007755    UP000078542    UP000075809    UP000005205    + More
UP000215335    UP000019118    UP000030742    UP000078492    UP000053825    UP000007266    UP000076502    UP000002358    UP000008237    UP000036403    UP000053097    UP000075883    UP000075886    UP000075884    UP000030765    UP000192223    UP000078540    UP000242457    UP000000311    UP000245037    UP000075881    UP000075900    UP000092553    UP000076408    UP000037069    UP000075880    UP000075920    UP000009192    UP000007798    UP000053105    UP000008820    UP000235965    UP000075903    UP000008792    UP000075902    UP000075882    UP000076407    UP000075840    UP000069272    UP000000673    UP000075885    UP000069940    UP000000304    UP000002282    UP000000803    UP000192221    UP000001070    UP000268350    UP000007801    UP000001819    UP000001292    UP000008711    UP000095301    UP000002320    UP000027135    UP000092445    UP000092444    UP000092443    UP000092460    UP000015103    UP000078200    UP000095300    UP000009046    UP000091820    UP000079169   

PRIDE

Q94515   

Pfam

PF08557   Lipid_DES        + More
PF00487   FA_desaturase

Interpro

IPR013866   Sphingolipid_d4-desaturase_N        + More
IPR011388   DES1/DES2       
IPR005804   FA_desaturase_dom       

CDD

cd03508  Delta4-sphingolipid-FADS-like

ProteinModelPortal

S4NTW3   A0A194PUI3   A0A0N1IBR5   A0A0U2F3C6   A0A1V0M859   A0A0P0EUM9   + More
A0A068FL45   A0A0M3L9M0   A0A1L8D6K0   F4WK44   A0A195C9F4   A0A151WZG4   A0A158NU25   A0A232EM57   J3JZJ8   U4UZD0   A0A195DJS5   A0A0L7QQN3   D2A4B6   A0A154PG59   K7J7E6   E2BYS5   A0A0J7L0W1   A0A026X049   A0A182LVN0   A0A1Y1N0K7   U5EVM8   A0A0C9QPJ5   A0A182Q6A3   A0A182N3S0   A0A084WI92   A0A1W4XBA7   A0A151I510   A0A2A3EA26   E2AQB5   A0A2P8ZC12   A0A182KFW3   A0A182RAH5   A0A0M4E023   A0A182YC85   A0A0L0C609   A0A1L8DYD9   W6AC26   A0A182IVI4   A0A182WD40   B4KGG4   A0A0A1X6P5   B4MUZ5   A0A0M9A5R4   Q16KB1   A0A2J7PLZ8   A0A182UQS6   A0A2M4BUA5   A0A2M4BU34   B4LR75   A0A2M3Z247   A0A182U767   A0A182KT82   A0A182X060   A0A182HPL9   A0A1Y9G890   W5JE68   A0A182P1G2   A0A2M4AE01   A0A023EQQ3   B4Q454   W8BT89   B4NZS7   Q94515   A0A1W4UBA5   B4JC21   A0A3B0JVI8   B3MMQ3   Q29PM1   A0A1Q3FHR6   B4I1N5   B3N5A3   A0A1I8N8N2   B0XIJ3   A0A0K8W533   A0A067R925   A0A023F8Z7   A0A1A9Z9E4   D3TPD7   A0A1L8EFN4   A0A1A9Y516   A0A1B0AWY5   A0A224XNM3   R4G5H9   A0A1A9UYB0   A0A1I8NTX7   A0A0V0G5D3   E0VSV1   R4WRN7   A0A1B6HT95   A0A0K8TSN4   A0A1A9VZS1   A0A1S3D9P6   A0A1B6FM57   A0A1B6LGA4  

KEGG

101744040    K04712 sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5] | (RefSeq) sphingolipid

PATHWAY

00600    Sphingolipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0042284   GO:0016021   GO:0030148   GO:0046513   GO:0007053   GO:0070938   GO:0016006   GO:0005739   GO:0007283   GO:0005886   GO:0006629   GO:0005488   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

Length:

321

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

90.5259200000001

Exp number, first 60 AAs:

14.64426

Total prob of N-in:

0.56450

POSSIBLE N-term signal

sequence

inside

1  -  69

TMhelix

70  -  92

outside

93  -  106

TMhelix

107  -  124

inside

125  -  207

TMhelix

208  -  230

outside

231  -  321

 

 

Pi

2.115798

Theta

6.052841

Tajima's D

0.247518

CLR

11.763178

CSRT

0.465276736163192

Interpretation

Uncertain