Gene

KWMTBOMO14160  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011412

Annotation

isocitrate_dehydrogenase_[Bombyx_mori]

Location

Bomo_Chr23(+):19518680-19525754      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 2.561

CDS

ATGGCTGTGCGTTTGTTAACTAAATTGAAGGTTTTGCCTGATGTGCGCGGGTCTGTGAATCTCAGCTCGAAAGCAGCGCCCGCTACATTATCGGATTTCGATGTCCAGCACAAGACTCCCGTTATCAGGAAACAGAAGCTGATTCCTAAGGCGCAATACGGCGGTCGTCACGCGGTGACCATGCTCCCTGGAGGCGGTATCGGTCCTGAGTGCATGGGATACGTTCGCGACATATTCAAATACATCGGTGCTCCTATTGACTTCGAAGTGGTGGACATTGACCCAACGATGGACAATGATGATGATGTCCAATATGCTATAACGACCATTAAGAGGAACGGTGTGGGGCTAAAGGGCAACATTGAAACCAAAAGTGAGGCAGCCTATGTGACGTCACGCAATGTGGCTCTCAGAAACGAACTGGACATGTATGCTTACATACTGAACTGTAAATCTTACCCTGGCGTTGCGACCAGACATAAGGACATTGATGTTGTTATTATCAGACAGAACACAGAAGGTGAATACGCTATGTTGGAACACGAATCCGTGAATGGTGTGGTCGAGTCAATGAAAGTGGTGACAGCTGACAACTCGGAGAGGGTGGCCAGGTTCGCCTTCGAATTCGCCAAGAAAAACGGCAGGAAGAAGGTAACAACGGTTCACAAAGCCAACATCATGAAGTTATCCGATGGCTTATTCTTGGAGACGTCACGTCGGCTCGCCAAGGAGTACCCGGACATAGAACACAACGATATGATCATTGACAACTGTTGCATGCAGCTCGTCGCAAAGCCACACCAGTTTGATGTTATGCTGATGACTAATCTGTACGGGTCCATTGTCTCGAACGTGGTCTGCGGGCTGTTGGGCGGAGCCGGCCTGCTCTCCGGTAGGAACTACGGCGACCACTACGCTGTATTCGAACCTGGCACTAGGAACACAGGTACCGCCATCGCCGGGAAGAACATTGCCAATCCGATCGCCATGATCAACGCCTCCATAGACATGCTGGAGCATTTGGGCCATCAGTTCCACGCGTCGCTACTCCGCCGCGCCATAAACAAGACGATCAATGTGGACCGCGTACTCACCCCGGATTTGGGCGGATCTAATACCTCCACAGATGTCGTGGGCGCCATCTTACAAAATGTCGGGCGCTGCTAG

Protein

MAVRLLTKLKVLPDVRGSVNLSSKAAPATLSDFDVQHKTPVIRKQKLIPKAQYGGRHAVTMLPGGGIGPECMGYVRDIFKYIGAPIDFEVVDIDPTMDNDDDVQYAITTIKRNGVGLKGNIETKSEAAYVTSRNVALRNELDMYAYILNCKSYPGVATRHKDIDVVIIRQNTEGEYAMLEHESVNGVVESMKVVTADNSERVARFAFEFAKKNGRKKVTTVHKANIMKLSDGLFLETSRRLAKEYPDIEHNDMIIDNCCMQLVAKPHQFDVMLMTNLYGSIVSNVVCGLLGGAGLLSGRNYGDHYAVFEPGTRNTGTAIAGKNIANPIAMINASIDMLEHLGHQFHASLLRRAINKTINVDRVLTPDLGGSNTSTDVVGAILQNVGRC

Uniprot

H9JPF8   D2Y061   A0A3S2PKZ9   A0A2A4IXR8   A0A212FD56   A0A2W1BDA7   + More
A0A0N1IPU9   A0A194PUI8   J3JXV8   A0A2J7QPR1   A0A2J7QPP0   V5G5L5   V5GMP4   D6WKK8   A0A1B6EP28   A0A1W4XJK9   A0A1B6M9F3   A0A1B6LLX4   A0A1B6GER4   A0A0A9Z381   A0A0A9XEF1   A0A0K8SEL1   A0A0T6B0Y2   A0A1Y1LHK1   A0A224XRA7   A0A023F9I4   A0A069DSX8   A0A182XWJ8   A0A182M7F3   A0A0J7KFU7   A0A182RFW2   A0A182JY75   A0A182VYC3   A0A084VR08   U5EIY4   A0A182TTJ8   A0A182IYP5   A0A182LQM4   A0A182NMU7   A0A182HZL9   A0A1B6CXN1   Q7QK78   F5HIU6   A0A182WZH2   A0A182V8Y5   A0A182P4G8   A0A2M4A980   A0A2M4BR48   A0A182Q0M5   A0A2M3ZGD6   W5J9R2   A0A182F8A8   A0A1B6DSN8   A0A2M4A8S1   A0A2M4BQN4   A0A195C7W4   A0A336MPM4   A0A0P4VIG3   A0A336MYW2   A0A336MNC9   R4G839   A0A158NU28   A0A336MM72   Q0IEC9   A0A151WZF3   T1DPW9   Q0IED1   Q0IED0   Q0IEC8   A0A195DJK4   A0A182H9M6   A0A195FJX2   E2BYS0   A0A023ER54   E1ZZ09   A0A3L8DW09   B0WQY4   A0A151I4K5   A0A088AKC5   A0A1L8E0A2   A0A1L8E034   A0A1Q3FJE5   A0A1Q3FJS5   A0A0C9Q5R0   A0A0K8TU98   A0A1L8E0A5   E9IRS5   A0A0Q9XCE3   B4K4V5   K7J3R3   I3RSE2   B4M4N6   A0A0Q9WC52   A8JRC1   A0A0N0BH85   A8JRB8   A0A0R1EBV6   Q8MT18   B3P6G3   B4PTH6  

Pubmed

19121390    22118469    28756777    26354079    22516182    23537049    + More
18362917    19820115    25401762    26823975    28004739    25474469    26334808    25244985    24438588    20966253    12364791    14747013    17210077    20920257    23761445    27129103    21347285    17510324    26483478    20798317    24945155    30249741    26369729    21282665    17994087    20075255    22328714    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304   

EMBL

BABH01010020    GU270852    ADB27114.1    RSAL01000005    RVE54421.1    NWSH01004998    + More
PCG64511.1    AGBW02009108    OWR51660.1    KZ150337    PZC71317.1    KQ460036    KPJ18417.1    KQ459593    KPI96414.1    APGK01024794    BT128080    KB740562    KB632399    AEE63041.1    ENN80293.1    ERL94805.1    NEVH01012088    PNF30553.1    PNF30552.1    GALX01003096    JAB65370.1    GALX01003097    JAB65369.1    KQ971342    EFA04017.1    GECZ01030088    JAS39681.1    GEBQ01007429    JAT32548.1    GEBQ01015311    JAT24666.1    GECZ01025032    GECZ01008976    JAS44737.1    JAS60793.1    GBHO01017690    GBHO01005273    GBRD01014477    GDHC01008502    JAG25914.1    JAG38331.1    JAG51349.1    JAQ10127.1    GBHO01025220    JAG18384.1    GBRD01014094    JAG51732.1    LJIG01016290    KRT81046.1    GEZM01055140    GEZM01055139    JAV73114.1    GFTR01005885    JAW10541.1    GBBI01001134    JAC17578.1    GBGD01001691    JAC87198.1    AXCM01009352    LBMM01008125    KMQ89124.1    ATLV01015393    KE525011    KFB40402.1    GANO01002447    JAB57424.1    APCN01001986    GEDC01019213    JAS18085.1    AAAB01008799    EAA03807.5    EGK96207.1    GGFK01003971    MBW37292.1    GGFJ01006333    MBW55474.1    AXCN02001558    GGFM01006828    MBW27579.1    ADMH02001967    ETN60148.1    GEDC01018701    GEDC01009311    GEDC01008620    JAS18597.1    JAS27987.1    JAS28678.1    GGFK01003848    MBW37169.1    GGFJ01006228    MBW55369.1    KQ978143    KYM96740.1    UFQT01001589    SSX31079.1    GDKW01002010    JAI54585.1    SSX31078.1    SSX31081.1    ACPB03011537    GAHY01001642    JAA75868.1    ADTU01026248    SSX31080.1    CH477695    EAT37170.1    KQ982638    KYQ53280.1    GAMD01002964    JAA98626.1    EAT37169.1    EAT37171.1    EAT37168.1    KQ980794    KYN13075.1    JXUM01121172    KQ566470    KXJ70107.1    KQ981522    KYN40656.1    GL451506    EFN79170.1    GAPW01001963    JAC11635.1    GL435250    EFN73576.1    QOIP01000004    RLU23958.1    DS232047    EDS33071.1    KQ976445    KYM86036.1    GFDF01001980    JAV12104.1    GFDF01001981    JAV12103.1    GFDL01007305    JAV27740.1    GFDL01007302    JAV27743.1    GBYB01009433    JAG79200.1    GDAI01000083    JAI17520.1    GFDF01001975    JAV12109.1    GL765283    EFZ16684.1    CH933806    KRG01943.1    EDW16108.2    JQ611724    AFK29227.1    CH940652    EDW59597.2    KRF78948.1    AE014297    ABW08764.1    KQ435759    KOX75664.1    BT082126    ABW08763.1    ACQ57833.1    CM000160    KRK04455.1    AY118436    AAF56494.2    AAM48465.1    CH954182    EDV53633.1    EDW98716.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000053240    UP000053268    + More
UP000019118    UP000030742    UP000235965    UP000007266    UP000192223    UP000076408    UP000075883    UP000036403    UP000075900    UP000075881    UP000075920    UP000030765    UP000075902    UP000075880    UP000075882    UP000075884    UP000075840    UP000007062    UP000076407    UP000075903    UP000075885    UP000075886    UP000000673    UP000069272    UP000078542    UP000015103    UP000005205    UP000008820    UP000075809    UP000078492    UP000069940    UP000249989    UP000078541    UP000008237    UP000000311    UP000279307    UP000002320    UP000078540    UP000005203    UP000009192    UP000002358    UP000008792    UP000000803    UP000053105    UP000002282    UP000008711   

PRIDE

H9JPF8    D2Y061    A0A088AKC5    A8JRC1    A8JRB8    Q8MT18    + More

Pfam

PF00180   Iso_dh

Interpro

IPR024084   IsoPropMal-DH-like_dom        + More
IPR004434   Isocitrate_DH_NAD       

ProteinModelPortal

H9JPF8   D2Y061   A0A3S2PKZ9   A0A2A4IXR8   A0A212FD56   A0A2W1BDA7   + More
A0A0N1IPU9   A0A194PUI8   J3JXV8   A0A2J7QPR1   A0A2J7QPP0   V5G5L5   V5GMP4   D6WKK8   A0A1B6EP28   A0A1W4XJK9   A0A1B6M9F3   A0A1B6LLX4   A0A1B6GER4   A0A0A9Z381   A0A0A9XEF1   A0A0K8SEL1   A0A0T6B0Y2   A0A1Y1LHK1   A0A224XRA7   A0A023F9I4   A0A069DSX8   A0A182XWJ8   A0A182M7F3   A0A0J7KFU7   A0A182RFW2   A0A182JY75   A0A182VYC3   A0A084VR08   U5EIY4   A0A182TTJ8   A0A182IYP5   A0A182LQM4   A0A182NMU7   A0A182HZL9   A0A1B6CXN1   Q7QK78   F5HIU6   A0A182WZH2   A0A182V8Y5   A0A182P4G8   A0A2M4A980   A0A2M4BR48   A0A182Q0M5   A0A2M3ZGD6   W5J9R2   A0A182F8A8   A0A1B6DSN8   A0A2M4A8S1   A0A2M4BQN4   A0A195C7W4   A0A336MPM4   A0A0P4VIG3   A0A336MYW2   A0A336MNC9   R4G839   A0A158NU28   A0A336MM72   Q0IEC9   A0A151WZF3   T1DPW9   Q0IED1   Q0IED0   Q0IEC8   A0A195DJK4   A0A182H9M6   A0A195FJX2   E2BYS0   A0A023ER54   E1ZZ09   A0A3L8DW09   B0WQY4   A0A151I4K5   A0A088AKC5   A0A1L8E0A2   A0A1L8E034   A0A1Q3FJE5   A0A1Q3FJS5   A0A0C9Q5R0   A0A0K8TU98   A0A1L8E0A5   E9IRS5   A0A0Q9XCE3   B4K4V5   K7J3R3   I3RSE2   B4M4N6   A0A0Q9WC52   A8JRC1   A0A0N0BH85   A8JRB8   A0A0R1EBV6   Q8MT18   B3P6G3   B4PTH6  

PDB

5YVT     E-value=2.69676e-96,     Score=898

KEGG

100329146    K00030 isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] | (RefSeq) isocitrate dehydrogenase

PATHWAY

00020    Citrate cycle (TCA cycle) - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01210    2-Oxocarboxylic acid metabolism - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0004449   GO:0006099   GO:0016616   GO:0006102   GO:0005739   GO:0005198   GO:0030126   GO:0005488   GO:0005507   GO:0004713   GO:0016491   GO:0015930   GO:0055114  

Length:

388

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

8.31627999999998

Exp number, first 60 AAs:

0.01306

Total prob of N-in:

0.06480

outside

1  -  388

 

 

Pi

17.558935

Theta

15.763533

Tajima's D

-0.572176

CLR

1.274129

CSRT

0.224438778061097

Interpretation

Uncertain