Gene

KWMTBOMO14124

Pre Gene Modal

BGIBMGA011393

Annotation

putative_BR_serine/threonine-protein_kinase_[Danaus_plexippus]

Location

Bomo_Chr23(+):18283732-18306366      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 4.1

CDS

ATGCTGGGTGAGAAATACGATGGTCGGAGGGCGGACGTCTGGTCGTGCGGTGTCATCTTGTACGCACTTCTCGTCGGTGCGCTGCCTTTTGACGATGATAATTTACGTCAATTACTTGAAAAGGTGAAACGAGGAGTGTTTCACGTGCCGCACTTTGTACCACCTGACTGCCAACAACTACTGCGTGGAATGATAGAAGTGAATCCGGAGAAGAGAATGACTTTGGCAGAGATAACGAGACATCCATGGGTAACTGCCGGCGGACGAGGAGAACTCGAACAAGAGTTGCCAATGATGGAAGTTGTTCAAACTAGAGTACTGCCTTCAGCTGATGCTGTTGATCCTGATGTTTTACAGGCAATGTGCAGCTTAGGTTGTTTCAAGCAAAGAGAGAAGCTGGTGCAAGAACTGTTAAGTCCGCATCACAACACGGAGAAGGTGATATACTTTTTGCTGCTGGAGCGGAAGCGCAGGCGTCCGGCGCGCGAGGACGAGGCTCGGCCTCCGCCCCCCGCCGCGCCCCCCGCCACCGCTGCCGCCCCCGACCCCCCACGGAAACGGCTCGACACCTGTCGGGTGAACGGACAGTCTGTTCATTTCGGGCAGATTAGTGAGGGATCGCCCATCACTCCGAGAAGGTCTCAGTTGAGGTCATCATCGAGTCGACGTACTGAGGGACGAAGTTCACCGCAGCTGTCCGCCAGCCCACCAGCTGGCCACACACCACATCGCGTGTCGTCGTTGGGAGGAACGCCGGCAACACCGGGTTCGCCATTAGCGTCGCCTTCCGTCCGGGAGCACCATCACCAGAGAGCGAACTCTACTGGACCGACGATCAGCCTCAATATCGGTGGCGAGCCCGGGGAGGCGGTGATCATTGTAAACGAGACCCCGTCTGGCCCGGCCGTCGCTGCCAGGCCGCACAGCCCGACGCAGTCACACCGAGTCAGAGAGCGGTCGTCCCTCCCCGGGCCCCCGACGGCGCAGGCCCCGCCCTCACTCTTCCCCAACATAGGACAGATTGGAGGCGTCCCTAACGCTGCGGCAAGCGCATCGGCCCCATGGAGGGTGCGTTTGGCCACCATCAAGAACTCGTTCCTGGGTTCGCCGAGATTTCATAGGCGGAAAATGCAGACATCATCGGAGGAAGTTCATCTGACGCCCGAATCATCACCGGAGCTGACGAAGAGGTCCTGGTTCGGGTCCCTCCTCCTGTCCGCTGACAAGGAGGAAACGTTCACGGCCCTCGTCAAAGGGAAACCTCTGGCCACCGTCAAAGCCGATTTGATACACGCCTTTTTGAGTATAGCAGAATTGTCGCACAGCGTTATAAGTCCAATGTCGTTCCGCGTCGAGTACAAGAGAGGGTCGAACGCGCCCGCCATGTTCCAGAGGCACGTCAGGTTTCAGGTCGATATATCGACTATAACGAAGACAGCCGAGGAGAACGGGAAGGACAACTTGTTCGCGATAACGTTCACCTTACTGTCGGGCAACATCCGTCGGTTCCGTCGCGTGTGCGAGGTGGTGCAGGCGGCCGTGAGCCGGGCGTCCGGCGCCACGCGGCACGCCGTCCTGCACCCCCCCTCGCCCTGCGCGCACCGCCGACACGTGCACCCCGCAGCTTCCAACGAGATCCCGGACAGTCCGGAGGCGCTGGGCGGGGAACCGGACAGCGACTCCTCAATGTTCGACTCCAGGAGTCCGGCGCCCACGCCCACCAGCCACACCTCCATAGACCAACTCGATCAGAACGGGACACATCTTCTAGGGTCCAGCTCTTCGGTGACCAGCGGCTCAAGTGGCTACAAACAGTGCGGAAGAAGACGACCGGCGGAACCGGCCTCAGCATCACTCGACCGCGAGATCATGAGTTGTGGCCGTGATATACCCGAATGCCGGGAGGCGGCCTCCTCGCCGCGCCGGGGGCTTGAGGCCCGCGACGCGTCACTCAAGGACGCCCTCCGGAGGAACAACTCGCTGAGGGATCGGCGTGACGTCACTCCGACCACGACCATCGCGTGA

Protein

MLGEKYDGRRADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHVPHFVPPDCQQLLRGMIEVNPEKRMTLAEITRHPWVTAGGRGELEQELPMMEVVQTRVLPSADAVDPDVLQAMCSLGCFKQREKLVQELLSPHHNTEKVIYFLLLERKRRRPAREDEARPPPPAAPPATAAAPDPPRKRLDTCRVNGQSVHFGQISEGSPITPRRSQLRSSSSRRTEGRSSPQLSASPPAGHTPHRVSSLGGTPATPGSPLASPSVREHHHQRANSTGPTISLNIGGEPGEAVIIVNETPSGPAVAARPHSPTQSHRVRERSSLPGPPTAQAPPSLFPNIGQIGGVPNAAASASAPWRVRLATIKNSFLGSPRFHRRKMQTSSEEVHLTPESSPELTKRSWFGSLLLSADKEETFTALVKGKPLATVKADLIHAFLSIAELSHSVISPMSFRVEYKRGSNAPAMFQRHVRFQVDISTITKTAEENGKDNLFAITFTLLSGNIRRFRRVCEVVQAAVSRASGATRHAVLHPPSPCAHRRHVHPAASNEIPDSPEALGGEPDSDSSMFDSRSPAPTPTSHTSIDQLDQNGTHLLGSSSSVTSGSSGYKQCGRRRPAEPASASLDREIMSCGRDIPECREAASSPRRGLEARDASLKDALRRNNSLRDRRDVTPTTTIA

Similarity

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Uniprot

A0A212F6J2   A0A3S2NM17   A0A194PYL0   A0A2H1VKX8   D2A4R1   A0A067R8T2   + More
A0A1S4EY07   Q17M45   A0A182VAT9   A0A182Y1X2   A0A084WB46   A0A182QH29   W5J2F6   A0A182KST8   A0A182UL29   A0A182J379   A0A182KGZ7   A0A182TAX8   B0WEJ9   B4ITX4   A0A195BDB0   A0A195FVZ0   F4WM56   A0A151IGG1   A0A151WFE5   A0A195DCL6   A0A158P3J7   A0A182FUF5   A0A026WXE7   A0A182XDA3   A0A182HPY6   A0A182MR70   E1ZUV7   A0A3L8E0G9   A0A088ARN5   E2B6I0   A0A0A9XFJ8   K7IXS0   A0A182NPG1   A0A1B6D6G2   A0A310SSE5   A0A182W9A0   A0A194RQG2   A0A336N0U3   A0A2H8TI99   A0A2S2N893   X1WJ05   A0A2S2NLE4   A0A182PBM7   A0A1I7ZB52   A0A1I7ZBH7   A0A1I7ZBP5   F1KST4   A0A0M3HSH8   J9FHP8   A0A0H5S3S8   A0A158PRY1   A0A016UZV9   A0A016UX46   A0A016UXT6   A0A0D6M8Z6   T1JDV5   A0A1S3J078  

Pubmed

22118469    26354079    18362917    19820115    24845553    17510324    + More
25244985    24438588    20920257    23761445    20966253    17994087    17550304    21719571    21347285    24508170    20798317    30249741    25401762    20075255    26392177    21685128    17885136    25730766   

EMBL

AGBW02010004    OWR49360.1    RSAL01000005    RVE54391.1    KQ459593    KPI96240.1    + More
ODYU01003119    SOQ41475.1    KQ971344    EFA05190.2    KK852809    KDR16003.1    CH477208    EAT47800.1    ATLV01022312    KE525331    KFB47440.1    AXCN02001828    ADMH02002188    ETN57911.1    DS231910    EDS45715.1    CH891734    EDW99837.2    KQ976519    KYM82175.1    KQ981264    KYN44009.1    GL888217    EGI64700.1    KQ977726    KYN00311.1    KQ983219    KYQ46552.1    KQ980989    KYN10582.1    ADTU01001329    KK107069    EZA60730.1    APCN01003284    AXCM01000926    GL434297    EFN75049.1    QOIP01000002    RLU25983.1    GL445973    EFN88724.1    GBHO01027734    JAG15870.1    GEDC01016026    JAS21272.1    KQ760869    OAD58767.1    KQ459875    KPJ19639.1    UFQS01004145    UFQT01000829    UFQT01004145    SSX16209.1    SSX27442.1    SSX35535.1    GFXV01000996    GFXV01001317    GFXV01001936    MBW12801.1    MBW13122.1    MBW13741.1    GGMR01000824    MBY13443.1    ABLF02021666    ABLF02021669    GGMR01005329    MBY17948.1    JI165285    ADY40938.1    ADBV01000574    EJW86869.1    LN856865    CRZ23355.1    UZAD01013233    VDN92681.1    JARK01001359    EYC19993.1    EYC19994.1    EYC19995.1    KE124869    EPB76312.1    JH432114   

Proteomes

UP000007151    UP000283053    UP000053268    UP000007266    UP000027135    UP000008820    + More
UP000075903    UP000076408    UP000030765    UP000075886    UP000000673    UP000075882    UP000075902    UP000075880    UP000075881    UP000075901    UP000002320    UP000002282    UP000078540    UP000078541    UP000007755    UP000078542    UP000075809    UP000078492    UP000005205    UP000069272    UP000053097    UP000076407    UP000075840    UP000075883    UP000000311    UP000279307    UP000005203    UP000008237    UP000002358    UP000075884    UP000075920    UP000053240    UP000007819    UP000075885    UP000095287    UP000036681    UP000004810    UP000006672    UP000038020    UP000278627    UP000024635    UP000085678   

Pfam

PF00069   Pkinase        + More
PF00782   DSPc
PF00488   MutS_V
PF05192   MutS_III

Interpro

IPR011009   Kinase-like_dom_sf        + More
IPR008271   Ser/Thr_kinase_AS       
IPR000719   Prot_kinase_dom       
IPR017441   Protein_kinase_ATP_BS       
IPR015940   UBA       
IPR000387   TYR_PHOSPHATASE_dom       
IPR020422   TYR_PHOSPHATASE_DUAL_dom       
IPR000340   Dual-sp_phosphatase_cat-dom       
IPR029021   Prot-tyrosine_phosphatase-like       
IPR020417   Atypical_DUSP       
IPR036187   DNA_mismatch_repair_MutS_sf       
IPR017261   DNA_mismatch_repair_MutS/MSH       
IPR007696   DNA_mismatch_repair_MutS_core       
IPR036678   MutS_con_dom_sf       
IPR000432   DNA_mismatch_repair_MutS_C       
IPR027417   P-loop_NTPase       

SUPFAM

SSF56112   SSF56112        + More
SSF52799   SSF52799       
SSF48334   SSF48334       
SSF52540   SSF52540       

Gene 3D

3.90.190.10     3.30.420.110    

CDD

cd00127  DSPc

ProteinModelPortal

A0A212F6J2   A0A3S2NM17   A0A194PYL0   A0A2H1VKX8   D2A4R1   A0A067R8T2   + More
A0A1S4EY07   Q17M45   A0A182VAT9   A0A182Y1X2   A0A084WB46   A0A182QH29   W5J2F6   A0A182KST8   A0A182UL29   A0A182J379   A0A182KGZ7   A0A182TAX8   B0WEJ9   B4ITX4   A0A195BDB0   A0A195FVZ0   F4WM56   A0A151IGG1   A0A151WFE5   A0A195DCL6   A0A158P3J7   A0A182FUF5   A0A026WXE7   A0A182XDA3   A0A182HPY6   A0A182MR70   E1ZUV7   A0A3L8E0G9   A0A088ARN5   E2B6I0   A0A0A9XFJ8   K7IXS0   A0A182NPG1   A0A1B6D6G2   A0A310SSE5   A0A182W9A0   A0A194RQG2   A0A336N0U3   A0A2H8TI99   A0A2S2N893   X1WJ05   A0A2S2NLE4   A0A182PBM7   A0A1I7ZB52   A0A1I7ZBH7   A0A1I7ZBP5   F1KST4   A0A0M3HSH8   J9FHP8   A0A0H5S3S8   A0A158PRY1   A0A016UZV9   A0A016UX46   A0A016UXT6   A0A0D6M8Z6   T1JDV5   A0A1S3J078  

PDB

4YOM     E-value=1.04797e-58,     Score=577

KEGG

101741779    K08796 BR serine/threonine kinase [EC:2.7.11.1] | (RefSeq) serine/threonine-protein kinase BRSK2

GO

GO:0004672   GO:0005524   GO:0004674   GO:0005737   GO:0050321   GO:0000226   GO:0035556   GO:0008138   GO:0016021   GO:0006298   GO:0030983   GO:0016301   GO:0007411   GO:0008088   GO:0034613   GO:0048489   GO:0045202   GO:0030425   GO:0030424   GO:0007416   GO:0030516   GO:0018105   GO:0007163   GO:0006468   GO:0008017   GO:0016887   GO:0019829   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

Length:

674

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

15.87303

Exp number, first 60 AAs:

15.87073

Total prob of N-in:

0.87259

POSSIBLE N-term signal

sequence

inside

1  -  12

TMhelix

13  -  30

outside

31  -  674

 

 

Pi

213.65309

Theta

167.923168

Tajima's D

1.988521

CLR

0.338356

CSRT

0.88255587220639

Interpretation

Uncertain