Gene

KWMTBOMO14083  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011217

Annotation

PREDICTED:_putative_fatty_acyl-CoA_reductase_CG5065_isoform_X1_[Plutella_xylostella]

Location

Bomo_Chr23(-):17578346-17588897      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

PlasmaMembrane   Reliability : 2.612

CDS

ATGGAAATTGGATTAGGTCTGTCGGAAGAACACCGTGCTGTACTTATTGACAATGTTAATATTATATTTCACGTGGCTGCAAGTGTAAGGTTTGATGACCCCTTGCAATATGCGGCCAAGCTGAATCTTCGTGGTACGCGAGAGGTCGTTGAACTAGCGAAGGCTATTAAAAACTTATCAGTGATGGTACACGTGTCGACTTCATACTCCAATACCAATAGAGAACTGGTGGAAGAGGTCATGTATCCCCCCCACGCTGACTGGAGGGAGGCCCTGGAGATCTGCGAGACGGTAGACGAGCACACGTTGCGCGTGCTGACTCCTAAGTACATTGGAGAGATGCCCAACACGTACACATTCACGAAGCAGCTAGCCGAGCACGTTGTCTACGAGCAGAAGGGCGTGCTGCCGGCCACCATTATCAGACCTTCGATCGTGATATCGAGTGCTACCGAGCCTGTGCCTGGCTGGATTGAGAACTACAACGGGCCAGTGGGCTTACTTGTGGCCAGCGGTAAAGGCATAATGCGAAGTCTGTACACCAACCCGGATCTGATGGCCGACTACATCCCGGTCGACGTGGCCATCCAGACCATCATCACCGCAGCTTGGCACAGAGGAACTAAGAAGTTGAAACCAACAGACGACATACCGATCTACAACTGCTGCTCGGGGAGTCTTTTCAAGATCACCATGAACGAGGTGGTGGAAATGGGGCGGTCGCTGGCAAAGGACATGCCCCTTGACGGCATGCTGTGGAGCGTCGGAGGAAATCTCACCACGTCCAAAACTTGGCACTACTTGAAGGTGCTGATACTGCATTTACTACCAGCTGTCTTCGTGGACACGTTGCTGCGTATACTAGGCAGGAAGCCGATGCTGGTCAAAGTCCAACGCCGCATATACATAGCCAATCTCGCTCTGCAATACTATTTGATCAAGCAATGGACGTTCGTCAATAGCAACCTGGTCGCCCTCCGTAGCTCCTTGAAGGAGACCGACAGAGCTGTCTTCTACTTCGACATAGAGGCGTTTGACCACAGAAAGTTCTTCTACGACTCGCTCATCGGAGCGAAGAAGTATCTGCTCAAAGAGAACTTGGACGACTTACCGAAGGCCAGAGCGCATTCGCGGAGATTAGATATCCTGGATTTCGTCGTCAAGACAGCGTTCTATTGCTACTGCGCCAACTGGGTGATGAAGATCGAAGTTGTTAACAGCGCTATTAACAGTGTCATTAATTGTATTTTCTATTAA

Protein

MEIGLGLSEEHRAVLIDNVNIIFHVAASVRFDDPLQYAAKLNLRGTREVVELAKAIKNLSVMVHVSTSYSNTNRELVEEVMYPPHADWREALEICETVDEHTLRVLTPKYIGEMPNTYTFTKQLAEHVVYEQKGVLPATIIRPSIVISSATEPVPGWIENYNGPVGLLVASGKGIMRSLYTNPDLMADYIPVDVAIQTIITAAWHRGTKKLKPTDDIPIYNCCSGSLFKITMNEVVEMGRSLAKDMPLDGMLWSVGGNLTTSKTWHYLKVLILHLLPAVFVDTLLRILGRKPMLVKVQRRIYIANLALQYYLIKQWTFVNSNLVALRSSLKETDRAVFYFDIEAFDHRKFFYDSLIGAKKYLLKENLDDLPKARAHSRRLDILDFVVKTAFYCYCANWVMKIEVVNSAINSVINCIFY

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Uniprot

A0A3S2NWB0   A0A1L8D6J1   A0A291P0W8   A0A291P0S7   A0A2A4K2J5   D9D5H4   + More
A0A2H1VIF0   A0A194PTF8   A0A194RP84   A0A2A4K2X0   A0A2H1W7P9   A0A291P0T9   A0A212F0B3   A0A1W4WCD3   A0A182W5X8   A0A182YH19   A0A182RVQ2   D6WYQ7   A0A182T8Q8   A0A182QWR0   Q7Q2V5   A0A1B0D476   A0A1Q3FZP3   A0A182FJU1   A0A182HAJ7   A0A182H739   A0A1Q3FZV2   A0A182MZT1   A0A1S4F214   E2ANI0   A0A084VR72   A0A232EY48   A0A182PWI9   B0WYE5   A0A336M1N3   A0A2P8Y5S4   A0A2J7RI68   A0A1B6DEA6   F4WQP0   A0A336MN30   A0A067QZV4   A0A1B6CCS7   A0A151X3W7   Q17I01   A0A182M7X1   A0A2J7RI77   K7IMK8   A0A2W1BB54   E2BYG6   A0A3L8DK87   A0A2J7RI66   A0A1J1HS41   A0A193CHN5   A0A2S2Q9S1   A0A310S7P0   A0A0L7RAZ7   B4MEM2   A0A1B6EWI8   A0A026WLT8   X1WJJ1   A0A0M4FAK5   A0A0L0CAW3   A0A336KKV2   A0A034WLE4   A0A1W4UW92   A0A0C9PTE7   A0A2J7PLY4   B4MTB8   Q29H47   T1PK20   B4JM90   A0A3B0J6S2   A0A1I8NAX1   B4H0C0   A0A224XJQ7   B3NSY8   W8C494   A0A1I8PJD5   B4Q1E3   B4I0H6   D9MWM8   A0A088AU73   Q29QU3   B4R5A2   Q9W459   B4L1G7   A0A158NRZ6   B3MY80   A0A0A9Y3V1   A0A195D184   A0A1I8P540   A0A1V0M883   T1I5B7   A0A2A4J8N1   A0A182FBM8  

EC Number

1.2.1.84

Pubmed

28986331    26354079    22118469    25244985    18362917    19820115    + More
12364791    14747013    17210077    26483478    17510324    20798317    24438588    28648823    29403074    21719571    24845553    20075255    28756777    30249741    27271970    17994087    24508170    26108605    25348373    15632085    25315136    24495485    17550304    20542116    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    21347285    25401762    28349297   

EMBL

RSAL01000135    RVE46259.1    GEYN01000142    JAV01987.1    MF687600    ATJ44526.1    + More
MF687543    ATJ44469.1    NWSH01000254    PCG77993.1    GU808250    ADI82774.1    ODYU01002489    SOQ40034.1    KQ459593    KPI96258.1    KQ459875    KPJ19658.1    PCG77992.1    ODYU01006856    SOQ49078.1    MF687544    ATJ44470.1    AGBW02011124    OWR47189.1    KQ971357    EFA08449.1    AXCN02001406    AAAB01008967    EAA13114.5    AJVK01024160    GFDL01002010    JAV33035.1    JXUM01122828    KQ566648    KXJ69945.1    JXUM01115484    JXUM01115485    KQ565885    KXJ70568.1    GFDL01002009    JAV33036.1    GL441227    EFN65009.1    ATLV01015505    KE525018    KFB40466.1    NNAY01001677    OXU23253.1    DS232187    EDS37022.1    UFQS01000395    UFQT01000395    SSX03595.1    SSX23960.1    PYGN01000896    PSN39593.1    NEVH01003505    PNF40529.1    GEDC01013326    JAS23972.1    GL888275    EGI63403.1    UFQT01001371    SSX30233.1    KK852809    KDR15980.1    GEDC01026034    JAS11264.1    KQ982562    KYQ54969.1    CH477244    EAT46275.1    AXCM01002370    PNF40526.1    KZ150519    PZC70617.1    GL451478    EFN79250.1    QOIP01000007    RLU20840.1    PNF40528.1    CVRI01000020    CRK90871.1    KU963290    ANN23960.1    GGMS01005285    MBY74488.1    KQ776822    OAD52159.1    KQ414617    KOC68039.1    CH940664    EDW62997.1    GECZ01027461    JAS42308.1    KK107152    EZA57010.1    ABLF02038949    ABLF02038951    ABLF02038964    ABLF02057284    CP012528    ALC49445.1    JRES01000755    KNC28614.1    UFQS01000581    UFQT01000581    SSX05119.1    SSX25480.1    GAKP01002566    JAC56386.1    GBYB01004642    GBYB01004643    JAG74409.1    JAG74410.1    NEVH01024421    PNF17348.1    CH963851    EDW75357.2    CH379064    EAL31911.1    KA648435    AFP63064.1    CH916371    EDV91851.1    OUUW01000003    SPP77737.1    CH479200    EDW29715.1    GFTR01006368    JAW10058.1    CH954180    EDV45957.1    GAMC01005674    JAC00882.1    CM000162    EDX02432.1    CH480819    EDW53007.1    HM483392    ADJ56409.1    BT024297    ABC86359.1    CM000366    EDX17198.1    AE014298    AAF46099.1    CH933810    EDW06688.2    ADTU01024364    ADTU01024365    ADTU01024366    CH902632    EDV32574.1    GBHO01016745    GBRD01003868    JAG26859.1    JAG61953.1    KQ977041    KYN06164.1    KU755483    ARD71193.1    ACPB03003261    NWSH01002428    PCG68321.1   

Proteomes

UP000283053    UP000218220    UP000053268    UP000053240    UP000007151    UP000192223    + More
UP000075920    UP000076408    UP000075900    UP000007266    UP000075901    UP000075886    UP000007062    UP000092462    UP000069272    UP000069940    UP000249989    UP000075884    UP000000311    UP000030765    UP000215335    UP000075885    UP000002320    UP000245037    UP000235965    UP000007755    UP000027135    UP000075809    UP000008820    UP000075883    UP000002358    UP000008237    UP000279307    UP000183832    UP000053825    UP000008792    UP000053097    UP000007819    UP000092553    UP000037069    UP000192221    UP000007798    UP000001819    UP000001070    UP000268350    UP000095301    UP000008744    UP000008711    UP000095300    UP000002282    UP000001292    UP000005203    UP000000304    UP000000803    UP000009192    UP000005205    UP000007801    UP000078542    UP000015103   

PRIDE

Q29QU3    Q9W459   

Pfam

PF03015   Sterile        + More
PF07993   NAD_binding_4
PF01084   Ribosomal_S18
PF02809   UIM
PF02770   Acyl-CoA_dh_M
PF13519   VWA_2
PF02771   Acyl-CoA_dh_N
PF00441   Acyl-CoA_dh_1
PF12796   Ank_2

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR013120   Male_sterile_NAD-bd       
IPR033640   FAR_C       
IPR026055   FAR       
IPR036870   Ribosomal_S18_sf       
IPR001648   Ribosomal_S18       
IPR003903   UIM_dom       
IPR009075   AcylCo_DH/oxidase_C       
IPR036465   vWFA_dom_sf       
IPR006091   Acyl-CoA_Oxase/DH_cen-dom       
IPR009100   AcylCoA_DH/oxidase_NM_dom       
IPR037069   AcylCoA_DH/ox_N_sf       
IPR036250   AcylCo_DH-like_C       
IPR013786   AcylCoA_DH/ox_N       
IPR006089   Acyl-CoA_DH_CS       
IPR002035   VWF_A       
IPR002110   Ankyrin_rpt       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       

SUPFAM

SSF51735   SSF51735        + More
SSF46911   SSF46911       
SSF56645   SSF56645       
SSF53300   SSF53300       
SSF47203   SSF47203       
SSF48403   SSF48403       

Gene 3D

4.10.640.10     1.10.540.10     3.40.50.410     1.25.40.20    

CDD

cd09071  FAR_C
cd00204  ANK

ProteinModelPortal

A0A3S2NWB0   A0A1L8D6J1   A0A291P0W8   A0A291P0S7   A0A2A4K2J5   D9D5H4   + More
A0A2H1VIF0   A0A194PTF8   A0A194RP84   A0A2A4K2X0   A0A2H1W7P9   A0A291P0T9   A0A212F0B3   A0A1W4WCD3   A0A182W5X8   A0A182YH19   A0A182RVQ2   D6WYQ7   A0A182T8Q8   A0A182QWR0   Q7Q2V5   A0A1B0D476   A0A1Q3FZP3   A0A182FJU1   A0A182HAJ7   A0A182H739   A0A1Q3FZV2   A0A182MZT1   A0A1S4F214   E2ANI0   A0A084VR72   A0A232EY48   A0A182PWI9   B0WYE5   A0A336M1N3   A0A2P8Y5S4   A0A2J7RI68   A0A1B6DEA6   F4WQP0   A0A336MN30   A0A067QZV4   A0A1B6CCS7   A0A151X3W7   Q17I01   A0A182M7X1   A0A2J7RI77   K7IMK8   A0A2W1BB54   E2BYG6   A0A3L8DK87   A0A2J7RI66   A0A1J1HS41   A0A193CHN5   A0A2S2Q9S1   A0A310S7P0   A0A0L7RAZ7   B4MEM2   A0A1B6EWI8   A0A026WLT8   X1WJJ1   A0A0M4FAK5   A0A0L0CAW3   A0A336KKV2   A0A034WLE4   A0A1W4UW92   A0A0C9PTE7   A0A2J7PLY4   B4MTB8   Q29H47   T1PK20   B4JM90   A0A3B0J6S2   A0A1I8NAX1   B4H0C0   A0A224XJQ7   B3NSY8   W8C494   A0A1I8PJD5   B4Q1E3   B4I0H6   D9MWM8   A0A088AU73   Q29QU3   B4R5A2   Q9W459   B4L1G7   A0A158NRZ6   B3MY80   A0A0A9Y3V1   A0A195D184   A0A1I8P540   A0A1V0M883   T1I5B7   A0A2A4J8N1   A0A182FBM8  

KEGG

101739328    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0102965   GO:0016021   GO:0006629   GO:0080019   GO:0010025   GO:0005777   GO:0035336   GO:0003735   GO:0006412   GO:0005840   GO:0003995   GO:0050660  

PANTHER

PTHR11011  

Length:

418

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

5.07626

Exp number, first 60 AAs:

0.01486

Total prob of N-in:

0.00831

outside

1  -  418

 

 

Pi

190.845923

Theta

22.912682

Tajima's D

-1.63495

CLR

35.445368

CSRT

0.0418479076046198

Interpretation

Possibly Positive selection