SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO14083  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA011217
Annotation
PREDICTED:_putative_fatty_acyl-CoA_reductase_CG5065_isoform_X1_[Plutella_xylostella]
Full name
Fatty acyl-CoA reductase      
Location in the cell
PlasmaMembrane   Reliability : 2.612
 

Sequence

CDS
ATGGAAATTGGATTAGGTCTGTCGGAAGAACACCGTGCTGTACTTATTGACAATGTTAATATTATATTTCACGTGGCTGCAAGTGTAAGGTTTGATGACCCCTTGCAATATGCGGCCAAGCTGAATCTTCGTGGTACGCGAGAGGTCGTTGAACTAGCGAAGGCTATTAAAAACTTATCAGTGATGGTACACGTGTCGACTTCATACTCCAATACCAATAGAGAACTGGTGGAAGAGGTCATGTATCCCCCCCACGCTGACTGGAGGGAGGCCCTGGAGATCTGCGAGACGGTAGACGAGCACACGTTGCGCGTGCTGACTCCTAAGTACATTGGAGAGATGCCCAACACGTACACATTCACGAAGCAGCTAGCCGAGCACGTTGTCTACGAGCAGAAGGGCGTGCTGCCGGCCACCATTATCAGACCTTCGATCGTGATATCGAGTGCTACCGAGCCTGTGCCTGGCTGGATTGAGAACTACAACGGGCCAGTGGGCTTACTTGTGGCCAGCGGTAAAGGCATAATGCGAAGTCTGTACACCAACCCGGATCTGATGGCCGACTACATCCCGGTCGACGTGGCCATCCAGACCATCATCACCGCAGCTTGGCACAGAGGAACTAAGAAGTTGAAACCAACAGACGACATACCGATCTACAACTGCTGCTCGGGGAGTCTTTTCAAGATCACCATGAACGAGGTGGTGGAAATGGGGCGGTCGCTGGCAAAGGACATGCCCCTTGACGGCATGCTGTGGAGCGTCGGAGGAAATCTCACCACGTCCAAAACTTGGCACTACTTGAAGGTGCTGATACTGCATTTACTACCAGCTGTCTTCGTGGACACGTTGCTGCGTATACTAGGCAGGAAGCCGATGCTGGTCAAAGTCCAACGCCGCATATACATAGCCAATCTCGCTCTGCAATACTATTTGATCAAGCAATGGACGTTCGTCAATAGCAACCTGGTCGCCCTCCGTAGCTCCTTGAAGGAGACCGACAGAGCTGTCTTCTACTTCGACATAGAGGCGTTTGACCACAGAAAGTTCTTCTACGACTCGCTCATCGGAGCGAAGAAGTATCTGCTCAAAGAGAACTTGGACGACTTACCGAAGGCCAGAGCGCATTCGCGGAGATTAGATATCCTGGATTTCGTCGTCAAGACAGCGTTCTATTGCTACTGCGCCAACTGGGTGATGAAGATCGAAGTTGTTAACAGCGCTATTAACAGTGTCATTAATTGTATTTTCTATTAA
Protein
MEIGLGLSEEHRAVLIDNVNIIFHVAASVRFDDPLQYAAKLNLRGTREVVELAKAIKNLSVMVHVSTSYSNTNRELVEEVMYPPHADWREALEICETVDEHTLRVLTPKYIGEMPNTYTFTKQLAEHVVYEQKGVLPATIIRPSIVISSATEPVPGWIENYNGPVGLLVASGKGIMRSLYTNPDLMADYIPVDVAIQTIITAAWHRGTKKLKPTDDIPIYNCCSGSLFKITMNEVVEMGRSLAKDMPLDGMLWSVGGNLTTSKTWHYLKVLILHLLPAVFVDTLLRILGRKPMLVKVQRRIYIANLALQYYLIKQWTFVNSNLVALRSSLKETDRAVFYFDIEAFDHRKFFYDSLIGAKKYLLKENLDDLPKARAHSRRLDILDFVVKTAFYCYCANWVMKIEVVNSAINSVINCIFY

Summary

Description
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Catalytic Activity
a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)
Similarity
Belongs to the fatty acyl-CoA reductase family.
EC Number
1.2.1.84
EMBL
RSAL01000135    RVE46259.1    GEYN01000142    JAV01987.1    MF687600    ATJ44526.1    + More
MF687543    ATJ44469.1    NWSH01000254    PCG77993.1    GU808250    ADI82774.1    ODYU01002489    SOQ40034.1    KQ459593    KPI96258.1    KQ459875    KPJ19658.1    PCG77992.1    ODYU01006856    SOQ49078.1    MF687544    ATJ44470.1    AGBW02011124    OWR47189.1    KQ971357    EFA08449.1    AXCN02001406    AAAB01008967    EAA13114.5    AJVK01024160    GFDL01002010    JAV33035.1    JXUM01122828    KQ566648    KXJ69945.1    JXUM01115484    JXUM01115485    KQ565885    KXJ70568.1    GFDL01002009    JAV33036.1    GL441227    EFN65009.1    ATLV01015505    KE525018    KFB40466.1    NNAY01001677    OXU23253.1    DS232187    EDS37022.1    UFQS01000395    UFQT01000395    SSX03595.1    SSX23960.1    PYGN01000896    PSN39593.1    NEVH01003505    PNF40529.1    GEDC01013326    JAS23972.1    GL888275    EGI63403.1    UFQT01001371    SSX30233.1    KK852809    KDR15980.1    GEDC01026034    JAS11264.1    KQ982562    KYQ54969.1    CH477244    EAT46275.1    AXCM01002370    PNF40526.1    KZ150519    PZC70617.1    GL451478    EFN79250.1    QOIP01000007    RLU20840.1    PNF40528.1    CVRI01000020    CRK90871.1    KU963290    ANN23960.1    GGMS01005285    MBY74488.1    KQ776822    OAD52159.1    KQ414617    KOC68039.1    CH940664    EDW62997.1    GECZ01027461    JAS42308.1    KK107152    EZA57010.1    ABLF02038949    ABLF02038951    ABLF02038964    ABLF02057284    CP012528    ALC49445.1    JRES01000755    KNC28614.1    UFQS01000581    UFQT01000581    SSX05119.1    SSX25480.1    GAKP01002566    JAC56386.1    GBYB01004642    GBYB01004643    JAG74409.1    JAG74410.1    NEVH01024421    PNF17348.1    CH963851    EDW75357.2    CH379064    EAL31911.1    KA648435    AFP63064.1    CH916371    EDV91851.1    OUUW01000003    SPP77737.1    CH479200    EDW29715.1    GFTR01006368    JAW10058.1    CH954180    EDV45957.1    GAMC01005674    JAC00882.1    CM000162    EDX02432.1    CH480819    EDW53007.1    HM483392    ADJ56409.1    BT024297    ABC86359.1    CM000366    EDX17198.1    AE014298    AAF46099.1    CH933810    EDW06688.2    ADTU01024364    ADTU01024365    ADTU01024366    CH902632    EDV32574.1    GBHO01016745    GBRD01003868    JAG26859.1    JAG61953.1    KQ977041    KYN06164.1    KU755483    ARD71193.1    ACPB03003261    NWSH01002428    PCG68321.1   
Pfam
PF03015   Sterile        + More
PF07993   NAD_binding_4
PF01084   Ribosomal_S18
PF02809   UIM
PF02770   Acyl-CoA_dh_M
PF13519   VWA_2
PF02771   Acyl-CoA_dh_N
PF00441   Acyl-CoA_dh_1
PF12796   Ank_2
Interpro
IPR036291   NAD(P)-bd_dom_sf        + More
IPR013120   Male_sterile_NAD-bd       
IPR033640   FAR_C       
IPR026055   FAR       
IPR036870   Ribosomal_S18_sf       
IPR001648   Ribosomal_S18       
IPR003903   UIM_dom       
IPR009075   AcylCo_DH/oxidase_C       
IPR036465   vWFA_dom_sf       
IPR006091   Acyl-CoA_Oxase/DH_cen-dom       
IPR009100   AcylCoA_DH/oxidase_NM_dom       
IPR037069   AcylCoA_DH/ox_N_sf       
IPR036250   AcylCo_DH-like_C       
IPR013786   AcylCoA_DH/ox_N       
IPR006089   Acyl-CoA_DH_CS       
IPR002035   VWF_A       
IPR002110   Ankyrin_rpt       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       
SUPFAM
SSF51735   SSF51735        + More
SSF46911   SSF46911       
SSF56645   SSF56645       
SSF53300   SSF53300       
SSF47203   SSF47203       
SSF48403   SSF48403       

Ontologies

Topology

Length:
418
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
5.07626
Exp number, first 60 AAs:
0.01486
Total prob of N-in:
0.00831
outside
1  -  418
 
 

Population Genetic Test Statistics

Pi
190.845923
Theta
22.912682
Tajima's D
-1.63495
CLR
35.445368
CSRT
0.0418479076046198
Interpretation
Possibly Positive selection

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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